CA3079477A1 - Amplicon region as epigenetic marker for the identification of non-classical monocytes - Google Patents

Amplicon region as epigenetic marker for the identification of non-classical monocytes Download PDF

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Publication number
CA3079477A1
CA3079477A1 CA3079477A CA3079477A CA3079477A1 CA 3079477 A1 CA3079477 A1 CA 3079477A1 CA 3079477 A CA3079477 A CA 3079477A CA 3079477 A CA3079477 A CA 3079477A CA 3079477 A1 CA3079477 A1 CA 3079477A1
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CA
Canada
Prior art keywords
amplicon
cells
seq
classical
methylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3079477A
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English (en)
French (fr)
Inventor
Sven Olek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Precision for Medicine GmbH
Original Assignee
Epiontis GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Epiontis GmbH filed Critical Epiontis GmbH
Publication of CA3079477A1 publication Critical patent/CA3079477A1/en
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA3079477A 2017-10-27 2018-10-26 Amplicon region as epigenetic marker for the identification of non-classical monocytes Pending CA3079477A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102017125335.1A DE102017125335B4 (de) 2017-10-27 2017-10-27 Amplikon-Region als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere nicht-klassischer Monozyten
DE102017125335.1 2017-10-27
PCT/EP2018/079406 WO2019081707A1 (en) 2017-10-27 2018-10-26 AMPLICON REGION AS AN EPIGENETIC MARKER FOR THE IDENTIFICATION OF NON-CLASSIC MONOCYTES

Publications (1)

Publication Number Publication Date
CA3079477A1 true CA3079477A1 (en) 2019-05-02

Family

ID=64024040

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3079477A Pending CA3079477A1 (en) 2017-10-27 2018-10-26 Amplicon region as epigenetic marker for the identification of non-classical monocytes

Country Status (8)

Country Link
US (1) US11680294B2 (enExample)
EP (1) EP3669001B1 (enExample)
JP (1) JP2021502806A (enExample)
CN (1) CN111247253A (enExample)
AU (1) AU2018356572A1 (enExample)
CA (1) CA3079477A1 (enExample)
DE (1) DE102017125335B4 (enExample)
WO (1) WO2019081707A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022191293A1 (ja) * 2021-03-12 2022-09-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 全単球及びcd16陽性単球の割合の測定方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2714933A4 (en) 2011-05-25 2014-12-31 Univ Brown METHODIZED METHOD FOR IDENTIFYING A CELL OR MIXING CELLS FOR THE PROGNOSIS AND DIAGNOSIS OF ILLNESSES AND FOR CELL HEALING THERAPIES
CN107941681B (zh) * 2013-04-19 2021-07-30 艾皮恩蒂斯有限公司 鉴定生物样品中定量细胞组成的方法
BR112015029299A2 (pt) * 2013-05-22 2017-07-25 Yeda Res & Dev subpopulação de monócitos humanos para tratamento de doenças e distúrbios oculares
GB201516975D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh PARK2 as epigenetic marker for the identification of immune cells, in particular monocytes

Also Published As

Publication number Publication date
US20200340053A1 (en) 2020-10-29
AU2018356572A1 (en) 2020-04-23
CN111247253A (zh) 2020-06-05
JP2021502806A (ja) 2021-02-04
EP3669001B1 (en) 2024-07-17
US11680294B2 (en) 2023-06-20
DE102017125335B4 (de) 2019-10-17
DE102017125335A1 (de) 2019-05-02
WO2019081707A1 (en) 2019-05-02
EP3669001A1 (en) 2020-06-24

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