CN111247253A - 作为用于鉴定免疫细胞尤其是非典型单核细胞的表观遗传标记的扩增子区 - Google Patents

作为用于鉴定免疫细胞尤其是非典型单核细胞的表观遗传标记的扩增子区 Download PDF

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Publication number
CN111247253A
CN111247253A CN201880068476.5A CN201880068476A CN111247253A CN 111247253 A CN111247253 A CN 111247253A CN 201880068476 A CN201880068476 A CN 201880068476A CN 111247253 A CN111247253 A CN 111247253A
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monocytes
cells
amplicon
methylation
seq
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CN201880068476.5A
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Chinese (zh)
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斯文·欧莱克
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Precision for Medicine GmbH
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Epiontis GmbH
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201880068476.5A 2017-10-27 2018-10-26 作为用于鉴定免疫细胞尤其是非典型单核细胞的表观遗传标记的扩增子区 Withdrawn CN111247253A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102017125335.1A DE102017125335B4 (de) 2017-10-27 2017-10-27 Amplikon-Region als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere nicht-klassischer Monozyten
DE102017125335.1 2017-10-27
PCT/EP2018/079406 WO2019081707A1 (en) 2017-10-27 2018-10-26 AMPLICON REGION AS AN EPIGENETIC MARKER FOR THE IDENTIFICATION OF NON-CLASSIC MONOCYTES

Publications (1)

Publication Number Publication Date
CN111247253A true CN111247253A (zh) 2020-06-05

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CN201880068476.5A Withdrawn CN111247253A (zh) 2017-10-27 2018-10-26 作为用于鉴定免疫细胞尤其是非典型单核细胞的表观遗传标记的扩增子区

Country Status (8)

Country Link
US (1) US11680294B2 (enExample)
EP (1) EP3669001B1 (enExample)
JP (1) JP2021502806A (enExample)
CN (1) CN111247253A (enExample)
AU (1) AU2018356572A1 (enExample)
CA (1) CA3079477A1 (enExample)
DE (1) DE102017125335B4 (enExample)
WO (1) WO2019081707A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022191293A1 (ja) * 2021-03-12 2022-09-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 全単球及びｃｄ１６陽性単球の割合の測定方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2714933A4 (en) 2011-05-25 2014-12-31 Univ Brown METHODIZED METHOD FOR IDENTIFYING A CELL OR MIXING CELLS FOR THE PROGNOSIS AND DIAGNOSIS OF ILLNESSES AND FOR CELL HEALING THERAPIES
CN107941681B (zh) * 2013-04-19 2021-07-30 艾皮恩蒂斯有限公司 鉴定生物样品中定量细胞组成的方法
BR112015029299A2 (pt) * 2013-05-22 2017-07-25 Yeda Res & Dev subpopulação de monócitos humanos para tratamento de doenças e distúrbios oculares
GB201516975D0 (en) * 2015-09-25 2015-11-11 Epiontis Gmbh PARK2 as epigenetic marker for the identification of immune cells, in particular monocytes

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Publication number Publication date
CA3079477A1 (en) 2019-05-02
US20200340053A1 (en) 2020-10-29
AU2018356572A1 (en) 2020-04-23
JP2021502806A (ja) 2021-02-04
EP3669001B1 (en) 2024-07-17
US11680294B2 (en) 2023-06-20
DE102017125335B4 (de) 2019-10-17
DE102017125335A1 (de) 2019-05-02
WO2019081707A1 (en) 2019-05-02
EP3669001A1 (en) 2020-06-24

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Legal Events

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PB01 Publication
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Address after: Berlin, Germany

Applicant after: Precision medical Co.,Ltd.

Address before: Berlin, Germany

Applicant before: EPIONTIS GmbH

WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20200605