JP2021500013A - B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 - Google Patents

B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 Download PDF

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JP2021500013A
JP2021500013A JP2020518675A JP2020518675A JP2021500013A JP 2021500013 A JP2021500013 A JP 2021500013A JP 2020518675 A JP2020518675 A JP 2020518675A JP 2020518675 A JP2020518675 A JP 2020518675A JP 2021500013 A JP2021500013 A JP 2021500013A
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oligonucleotide
nucleosides
nucleoside
oligonucleotides
antisense oligonucleotide
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Inventor
カムラー スサネ
カムラー スサネ
ロペス アナイス
ロペス アナイス
ミュラー ヘンリック
ミュラー ヘンリック
オトスン セーアン
オトスン セーアン
ピーダスン ルゲ
ピーダスン ルゲ
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of JP2021500013A publication Critical patent/JP2021500013A/ja
Priority to JP2021020438A priority Critical patent/JP7348922B2/ja
Priority to JP2023129333A priority patent/JP2023138687A/ja
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JP2020518675A 2017-10-16 2018-10-16 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 Ceased JP2021500013A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2021020438A JP7348922B2 (ja) 2017-10-16 2021-02-12 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子
JP2023129333A JP2023138687A (ja) 2017-10-16 2023-08-08 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP17196554 2017-10-16
EP17196554.4 2017-10-16
EP17208056 2017-12-18
EP17208056.6 2017-12-18
PCT/EP2018/078136 WO2019076842A1 (en) 2017-10-16 2018-10-16 NUCLEIC ACID MOLECULE FOR THE REDUCTION OF PAPD5 AND PAPD7 MRNA FOR THE TREATMENT OF HEPATITIS B INFECTION

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JP2021020438A Division JP7348922B2 (ja) 2017-10-16 2021-02-12 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子

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JP2021500013A true JP2021500013A (ja) 2021-01-07

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JP2020518675A Ceased JP2021500013A (ja) 2017-10-16 2018-10-16 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子
JP2021020438A Active JP7348922B2 (ja) 2017-10-16 2021-02-12 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子
JP2023129333A Pending JP2023138687A (ja) 2017-10-16 2023-08-08 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子

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JP2021020438A Active JP7348922B2 (ja) 2017-10-16 2021-02-12 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子
JP2023129333A Pending JP2023138687A (ja) 2017-10-16 2023-08-08 B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子

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US (4) US10953034B2 (enExample)
EP (1) EP3645723A1 (enExample)
JP (3) JP2021500013A (enExample)
KR (5) KR102585898B1 (enExample)
CN (2) CN111511914B (enExample)
AU (3) AU2018350693B2 (enExample)
BR (2) BR112020007417A2 (enExample)
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TW (3) TW202424191A (enExample)
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MA45496A (fr) 2016-06-17 2019-04-24 Hoffmann La Roche Molécules d'acide nucléique pour la réduction de l'arnm de padd5 ou pad7 pour le traitement d'une infection par l'hépatite b
EP3645723A1 (en) 2017-10-16 2020-05-06 H. Hoffnabb-La Roche Ag NUCLEIC ACID MOLECULE FOR REDUCTION OF PAPD5 AND PAPD7 mRNA FOR TREATING HEPATITIS B INFECTION
US11332733B2 (en) * 2018-02-12 2022-05-17 lonis Pharmaceuticals, Inc. Modified compounds and uses thereof
CR20210178A (es) 2018-07-03 2021-05-11 Hoffmann La Roche OLIGONUCLEÓTIDOS PARA MODULAR LA EXPRESIÓN DE TAU (Divisional 2021-0058)
AU2019300324A1 (en) 2018-07-13 2021-01-21 F. Hoffmann-La Roche Ag Oligonucleotides for modulating RTEL1 expression
JP7403777B2 (ja) * 2019-05-30 2023-12-25 ソウル大学校産学協力団 ウイルス感染及び活性抑制方法
CN113905744A (zh) * 2019-05-31 2022-01-07 阿利戈斯治疗公司 经修饰的间隙子寡核苷酸及其使用方法
EP4081217A1 (en) * 2019-12-24 2022-11-02 F. Hoffmann-La Roche AG Pharmaceutical combination of antiviral agents targeting hbv and/or an immune modulator for treatment of hbv
US20220160748A1 (en) * 2020-11-20 2022-05-26 Aligos Therapeutics, Inc. Conjugates of s-antigen transport inhibiting oligonucleotide polymers having enhanced liver targeting
WO2025199466A1 (en) 2024-03-22 2025-09-25 Purdue Research Foundation Liver-specific asialoglycoprotein receptor targeting ligands, conjugates comprising same, and related compositions and methods of use

Citations (2)

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