JP2021500013A - B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 - Google Patents
B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 Download PDFInfo
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- JP2021500013A JP2021500013A JP2020518675A JP2020518675A JP2021500013A JP 2021500013 A JP2021500013 A JP 2021500013A JP 2020518675 A JP2020518675 A JP 2020518675A JP 2020518675 A JP2020518675 A JP 2020518675A JP 2021500013 A JP2021500013 A JP 2021500013A
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
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- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021020438A JP7348922B2 (ja) | 2017-10-16 | 2021-02-12 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
| JP2023129333A JP2023138687A (ja) | 2017-10-16 | 2023-08-08 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17196554 | 2017-10-16 | ||
| EP17196554.4 | 2017-10-16 | ||
| EP17208056 | 2017-12-18 | ||
| EP17208056.6 | 2017-12-18 | ||
| PCT/EP2018/078136 WO2019076842A1 (en) | 2017-10-16 | 2018-10-16 | NUCLEIC ACID MOLECULE FOR THE REDUCTION OF PAPD5 AND PAPD7 MRNA FOR THE TREATMENT OF HEPATITIS B INFECTION |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021020438A Division JP7348922B2 (ja) | 2017-10-16 | 2021-02-12 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2021500013A true JP2021500013A (ja) | 2021-01-07 |
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020518675A Ceased JP2021500013A (ja) | 2017-10-16 | 2018-10-16 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
| JP2021020438A Active JP7348922B2 (ja) | 2017-10-16 | 2021-02-12 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
| JP2023129333A Pending JP2023138687A (ja) | 2017-10-16 | 2023-08-08 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021020438A Active JP7348922B2 (ja) | 2017-10-16 | 2021-02-12 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
| JP2023129333A Pending JP2023138687A (ja) | 2017-10-16 | 2023-08-08 | B型肝炎感染の治療用のPAPD5及びPAPD7 mRNAを低減させるための核酸分子 |
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| US (4) | US10953034B2 (enExample) |
| EP (1) | EP3645723A1 (enExample) |
| JP (3) | JP2021500013A (enExample) |
| KR (5) | KR102585898B1 (enExample) |
| CN (2) | CN111511914B (enExample) |
| AU (3) | AU2018350693B2 (enExample) |
| BR (2) | BR112020007417A2 (enExample) |
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| CL (1) | CL2020000945A1 (enExample) |
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| IL (2) | IL272566B2 (enExample) |
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| PH (1) | PH12020550436A1 (enExample) |
| RU (1) | RU2766360C2 (enExample) |
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Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA45496A (fr) | 2016-06-17 | 2019-04-24 | Hoffmann La Roche | Molécules d'acide nucléique pour la réduction de l'arnm de padd5 ou pad7 pour le traitement d'une infection par l'hépatite b |
| EP3645723A1 (en) | 2017-10-16 | 2020-05-06 | H. Hoffnabb-La Roche Ag | NUCLEIC ACID MOLECULE FOR REDUCTION OF PAPD5 AND PAPD7 mRNA FOR TREATING HEPATITIS B INFECTION |
| US11332733B2 (en) * | 2018-02-12 | 2022-05-17 | lonis Pharmaceuticals, Inc. | Modified compounds and uses thereof |
| CR20210178A (es) | 2018-07-03 | 2021-05-11 | Hoffmann La Roche | OLIGONUCLEÓTIDOS PARA MODULAR LA EXPRESIÓN DE TAU (Divisional 2021-0058) |
| AU2019300324A1 (en) | 2018-07-13 | 2021-01-21 | F. Hoffmann-La Roche Ag | Oligonucleotides for modulating RTEL1 expression |
| JP7403777B2 (ja) * | 2019-05-30 | 2023-12-25 | ソウル大学校産学協力団 | ウイルス感染及び活性抑制方法 |
| CN113905744A (zh) * | 2019-05-31 | 2022-01-07 | 阿利戈斯治疗公司 | 经修饰的间隙子寡核苷酸及其使用方法 |
| EP4081217A1 (en) * | 2019-12-24 | 2022-11-02 | F. Hoffmann-La Roche AG | Pharmaceutical combination of antiviral agents targeting hbv and/or an immune modulator for treatment of hbv |
| US20220160748A1 (en) * | 2020-11-20 | 2022-05-26 | Aligos Therapeutics, Inc. | Conjugates of s-antigen transport inhibiting oligonucleotide polymers having enhanced liver targeting |
| WO2025199466A1 (en) | 2024-03-22 | 2025-09-25 | Purdue Research Foundation | Liver-specific asialoglycoprotein receptor targeting ligands, conjugates comprising same, and related compositions and methods of use |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016051116A1 (fr) * | 2014-10-02 | 2016-04-07 | Dav | Dispositif et procédé de commande pour véhicule automobile |
| JP2017515862A (ja) * | 2014-05-15 | 2017-06-15 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | オリゴマーおよびオリゴマー・コンジュゲート |
Family Cites Families (98)
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