JP2021118906A5 - - Google Patents
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- Publication number
- JP2021118906A5 JP2021118906A5 JP2021077751A JP2021077751A JP2021118906A5 JP 2021118906 A5 JP2021118906 A5 JP 2021118906A5 JP 2021077751 A JP2021077751 A JP 2021077751A JP 2021077751 A JP2021077751 A JP 2021077751A JP 2021118906 A5 JP2021118906 A5 JP 2021118906A5
- Authority
- JP
- Japan
- Prior art keywords
- hap
- cap
- hydroxyapatite
- calcium phosphate
- biphasic calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000316 bone substitute Substances 0.000 claims 11
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 11
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 11
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 10
- 230000002051 biphasic effect Effects 0.000 claims 9
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 9
- 239000001506 calcium phosphate Substances 0.000 claims 9
- 235000011010 calcium phosphates Nutrition 0.000 claims 9
- 239000000463 material Substances 0.000 claims 9
- 239000011162 core material Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 238000004630 atomic force microscopy Methods 0.000 claims 6
- 239000002159 nanocrystal Substances 0.000 claims 6
- 239000008187 granular material Substances 0.000 claims 4
- 238000006243 chemical reaction Methods 0.000 claims 3
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 150000002191 fatty alcohols Chemical class 0.000 claims 2
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 2
- 239000011707 mineral Substances 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 claims 1
- 229910052753 mercury Inorganic materials 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000008055 phosphate buffer solution Substances 0.000 claims 1
- 238000002459 porosimetry Methods 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 239000011343 solid material Substances 0.000 claims 1
- 230000001954 sterilising effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17207235.7 | 2017-12-14 | ||
| EP17207235 | 2017-12-14 | ||
| JP2020532744A JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532744A Division JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021118906A JP2021118906A (ja) | 2021-08-12 |
| JP2021118906A5 true JP2021118906A5 (cg-RX-API-DMAC10.html) | 2021-12-02 |
| JP7249376B2 JP7249376B2 (ja) | 2023-03-30 |
Family
ID=60781527
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532744A Active JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
| JP2021077751A Active JP7249376B2 (ja) | 2017-12-14 | 2021-04-30 | 骨代替材料 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532744A Active JP6880330B2 (ja) | 2017-12-14 | 2018-12-13 | 骨代替材料 |
Country Status (18)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3083852A1 (en) | 2017-12-14 | 2019-06-20 | Geistlich Pharma Ag | Biphasic calcium phosphate/hydroxyapatite bone substitute material |
| CN114761048B (zh) | 2019-06-14 | 2023-05-02 | 盖斯特里希医药公司 | 骨替代材料的胶原基质或颗粒共混物 |
| US12539350B2 (en) | 2020-05-25 | 2026-02-03 | Dhawan Shrey | Ion-substituted bovine hydroxyapatite for bone regeneration |
| DE202021004032U1 (de) | 2020-08-29 | 2022-10-10 | BioScientific Designs d.o.o | Ein steriles Medizinprodukt als Knochenersatz, Zubereitung und Verwendung |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60220056A (ja) * | 1984-04-18 | 1985-11-02 | 三菱マテリアル株式会社 | 人工歯 |
| US4865602A (en) | 1986-11-06 | 1989-09-12 | Collagen Corporation | Gamma irradiation of collagen/mineral mixtures |
| DE3711426A1 (de) | 1987-04-04 | 1988-10-13 | Mtu Muenchen Gmbh | Implantat mit bioaktivem ueberzug |
| GB8813033D0 (en) | 1988-06-02 | 1988-07-06 | Geistlich Soehne Ag | Chemical compound |
| JPH07504106A (ja) | 1992-02-28 | 1995-05-11 | コラーゲン コーポレイション | 注射可能なセラミック組成物及びそれらの製造及び使用のための方法 |
| US5763092A (en) | 1993-09-15 | 1998-06-09 | Etex Corporation | Hydroxyapatite coatings and a method of their manufacture |
| IT1288038B1 (it) | 1996-04-30 | 1998-09-10 | Flametal S P A | Procedimento per la preparazione di rivestimenti di idrossiapatite |
| US6338752B1 (en) | 2000-04-20 | 2002-01-15 | Purzer Pharmaceutical Co., Ltd. | α-TCP/HAP biphasic cement and its preparing process |
| US20030026770A1 (en) | 2001-07-25 | 2003-02-06 | Szymaitis Dennis W. | Periodontal regeneration composition and method of using same |
| US20070026030A1 (en) | 2005-07-27 | 2007-02-01 | Berkeley Advanced Biomaterials, Inc. | Method of preparing rheological materials for bone and cartilage repair |
| ES2729425T3 (es) * | 2006-10-24 | 2019-11-04 | Biomet 3I Llc | Deposición de nanopartículas discretas sobre una superficie nanoestructurada de un implante |
| CN1974876B (zh) * | 2006-11-02 | 2010-07-07 | 华南理工大学 | 钛金属表面生物活性膜层及其喷砂-微弧氧化复合工艺 |
| CN102497891B (zh) | 2009-06-23 | 2015-05-27 | 盖斯特里希医药公司 | 骨替代材料 |
| US20130045360A1 (en) | 2010-01-29 | 2013-02-21 | Georgia Tech Research Corporation | Surface modification of implant devices |
| CN101850131A (zh) * | 2010-04-30 | 2010-10-06 | 武汉理工大学 | 晶核引导骨性结合的金属植入体表面改性的方法 |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| WO2012084214A1 (en) | 2010-12-22 | 2012-06-28 | Geistlich Pharma Ag | Bone substitute material |
| DE102011050183A1 (de) * | 2011-05-06 | 2012-11-08 | Aesculap Ag | Oberflächenprofilierter Gitterkörper |
| GB201122405D0 (en) * | 2011-12-23 | 2012-02-08 | Univ Aberdeen | Calcium phosphate material |
| EP2997077B1 (en) * | 2013-05-15 | 2018-11-07 | EURORESEARCH S.r.L. | Collagen powder, composition and use |
| NL2011195C2 (en) | 2013-07-18 | 2015-01-21 | Xpand Biotechnology B V | Method for producing an osteoinductive calcium phosphate and products thus obtained. |
| EP2826495A1 (en) | 2013-07-19 | 2015-01-21 | Geistlich Pharma AG | Biomimetic collagen-hydroxyapatite composite material |
| JP6813716B1 (ja) | 2017-12-14 | 2021-01-13 | ガイストリッヒ ファーマ アーゲー | 骨代替材料 |
| WO2019115795A1 (en) | 2017-12-14 | 2019-06-20 | Geistlich Pharma Ag | Dried implant composition and injectable aqueous implant formulation |
| CA3083852A1 (en) | 2017-12-14 | 2019-06-20 | Geistlich Pharma Ag | Biphasic calcium phosphate/hydroxyapatite bone substitute material |
-
2018
- 2018-12-13 CA CA3083852A patent/CA3083852A1/en active Pending
- 2018-12-13 AU AU2018382557A patent/AU2018382557B2/en active Active
- 2018-12-13 IL IL275203A patent/IL275203B2/en unknown
- 2018-12-13 MX MX2020005846A patent/MX2020005846A/es unknown
- 2018-12-13 TW TW107145009A patent/TWI852918B/zh not_active IP Right Cessation
- 2018-12-13 ES ES18816063T patent/ES2803976T3/es active Active
- 2018-12-13 SG SG11202004726YA patent/SG11202004726YA/en unknown
- 2018-12-13 HU HUE18816063A patent/HUE050062T2/hu unknown
- 2018-12-13 JP JP2020532744A patent/JP6880330B2/ja active Active
- 2018-12-13 DK DK18816063.4T patent/DK3544643T3/da active
- 2018-12-13 KR KR1020207016840A patent/KR102233325B1/ko active Active
- 2018-12-13 WO PCT/EP2018/084783 patent/WO2019115704A1/en not_active Ceased
- 2018-12-13 PL PL18816063T patent/PL3544643T3/pl unknown
- 2018-12-13 CN CN201880080248.XA patent/CN111465418B/zh active Active
- 2018-12-13 BR BR112020010213-0A patent/BR112020010213B1/pt active IP Right Grant
- 2018-12-13 EP EP18816063.4A patent/EP3544643B1/en active Active
- 2018-12-13 PT PT188160634T patent/PT3544643T/pt unknown
- 2018-12-14 US US16/220,331 patent/US11351287B2/en active Active
-
2019
- 2019-09-25 US US16/582,301 patent/US10646615B2/en active Active
-
2021
- 2021-04-30 JP JP2021077751A patent/JP7249376B2/ja active Active
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