JP2021073291A5 - - Google Patents
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- JP2021073291A5 JP2021073291A5 JP2021017236A JP2021017236A JP2021073291A5 JP 2021073291 A5 JP2021073291 A5 JP 2021073291A5 JP 2021017236 A JP2021017236 A JP 2021017236A JP 2021017236 A JP2021017236 A JP 2021017236A JP 2021073291 A5 JP2021073291 A5 JP 2021073291A5
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- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- conjugation
- antibody
- asgpr
- seq
- Prior art date
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023014370A JP7663616B2 (ja) | 2014-05-16 | 2023-02-02 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461994239P | 2014-05-16 | 2014-05-16 | |
| US61/994,239 | 2014-05-16 | ||
| US201462014504P | 2014-06-19 | 2014-06-19 | |
| US62/014,504 | 2014-06-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017512873A Division JP6836500B2 (ja) | 2014-05-16 | 2015-05-15 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023014370A Division JP7663616B2 (ja) | 2014-05-16 | 2023-02-02 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021073291A JP2021073291A (ja) | 2021-05-13 |
| JP2021073291A5 true JP2021073291A5 (enExample) | 2021-10-28 |
| JP7222004B2 JP7222004B2 (ja) | 2023-02-14 |
Family
ID=54480787
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017512873A Active JP6836500B2 (ja) | 2014-05-16 | 2015-05-15 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
| JP2021017236A Active JP7222004B2 (ja) | 2014-05-16 | 2021-02-05 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
| JP2023014370A Active JP7663616B2 (ja) | 2014-05-16 | 2023-02-02 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017512873A Active JP6836500B2 (ja) | 2014-05-16 | 2015-05-15 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023014370A Active JP7663616B2 (ja) | 2014-05-16 | 2023-02-02 | 自己免疫状態および炎症状態を治療するための方法および組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US10993990B2 (enExample) |
| EP (1) | EP3142691A4 (enExample) |
| JP (3) | JP6836500B2 (enExample) |
| CN (1) | CN106659774A (enExample) |
| AU (3) | AU2015258875B2 (enExample) |
| CA (2) | CA3185180A1 (enExample) |
| IL (2) | IL300029A (enExample) |
| WO (1) | WO2015175957A1 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6017422B2 (ja) | 2010-08-10 | 2016-11-02 | エコール・ポリテクニーク・フェデラル・ドゥ・ローザンヌ(ウペエフエル)Ecole Polytechnique Federale de Lausanne (EPFL) | 赤血球結合療法 |
| US9517257B2 (en) | 2010-08-10 | 2016-12-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| US9850296B2 (en) | 2010-08-10 | 2017-12-26 | Ecole Polytechnique Federale De Lausanne (Epfl) | Erythrocyte-binding therapeutics |
| KR20240154672A (ko) | 2014-02-21 | 2024-10-25 | 에꼴 뽈리떼끄닉 뻬데랄 드 로잔느 (으뻬에프엘) | 글리코타겟팅 치료제 |
| US10046056B2 (en) | 2014-02-21 | 2018-08-14 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| US10946079B2 (en) | 2014-02-21 | 2021-03-16 | Ecole Polytechnique Federale De Lausanne | Glycotargeting therapeutics |
| US10953101B2 (en) | 2014-02-21 | 2021-03-23 | École Polytechnique Fédérale De Lausanne (Epfl) | Glycotargeting therapeutics |
| KR20200031571A (ko) * | 2017-05-29 | 2020-03-24 | 가마맵스 파마 | 암 연관 면역억제의 억제제 |
| EP3638296A1 (en) | 2017-06-16 | 2020-04-22 | The University Of Chicago | Compositions and methods for inducing immune tolerance |
| SG11202011078VA (en) | 2018-05-09 | 2020-12-30 | Univ Chicago | Compositions and methods concerning immune tolerance |
| CN119613548A (zh) * | 2018-06-13 | 2025-03-14 | 鸿运华宁(杭州)生物医药有限公司 | APJ抗体及其与Elabela的融合蛋白质,以及其药物组合物和应用 |
| CN109620952A (zh) * | 2019-01-04 | 2019-04-16 | 北京中台恒基生物技术有限公司 | 一种肿瘤疫苗及其制备方法 |
| CN121971599A (zh) | 2019-02-25 | 2026-05-05 | 芝加哥大学 | 用与抗炎剂连接的ecm亲和肽治疗炎症性和自身免疫性病症的方法和组合物 |
| JP7546924B2 (ja) * | 2019-03-01 | 2024-09-09 | 国立大学法人 筑波大学 | アレルギー疾患を処置することに用いるための組成物 |
| CA3141327A1 (en) * | 2019-05-20 | 2020-11-26 | Pandion Operations, Inc. | Madcam targeted immunotolerance |
| US12448440B2 (en) * | 2019-08-23 | 2025-10-21 | Loyota University Of Chicago | Compositions comprising antibodies or antibody fragments which bind the P2X4 receptor |
| CN111544592B (zh) * | 2020-03-13 | 2022-05-03 | 中山大学附属第一医院 | 模式识别受体Dectin-1抑制剂对受体移植物的免疫保护及诱导免疫耐受的应用 |
| EP4181957A4 (en) | 2020-07-20 | 2024-08-07 | Deka Biosciences, Inc. | TWO-CYTOKINE FUSION PROTEIN COMPRISING IL-10 |
| US11859001B2 (en) | 2020-08-05 | 2024-01-02 | Synthekine, Inc. | IL12RB1-Binding molecules and methods of use |
| WO2022031870A1 (en) | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | IL27Rα BINDING MOLECULES AND METHODS OF USE |
| WO2022031890A1 (en) | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Ifngr2 binding molecules and methods of use |
| US12012457B1 (en) | 2020-08-05 | 2024-06-18 | Synthekine, Inc. | IL23R binding molecules and methods of use |
| BR112023001723A2 (pt) | 2020-08-05 | 2023-05-02 | Synthekine Inc | Moléculas de ligação à gp130 e métodos de uso |
| US12077594B2 (en) | 2020-08-05 | 2024-09-03 | Synthekine, Inc. | IL2RG binding molecules and methods of use |
| US12234291B2 (en) | 2020-08-05 | 2025-02-25 | Synthekine, Inc. | IL2RB binding molecules and methods of use |
| US12540188B2 (en) | 2020-08-05 | 2026-02-03 | Synthekine, Inc. | IL10Rα/IL2Rγ synthetic cytokines |
| EP4192880A4 (en) | 2020-08-05 | 2025-04-30 | Synthekine, Inc. | IL10 receptor-binding molecules and methods of use |
| US12291572B2 (en) | 2020-08-05 | 2025-05-06 | Synthekine, Inc. | IL12 receptor synthetic cytokines and methods of use |
| WO2022031885A2 (en) | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Il10ra binding molecules and methods of use |
| US12122839B2 (en) | 2020-08-05 | 2024-10-22 | Synthekine, Inc. | IFNGR binding synthetic cytokines and methods of use |
| CN116829585A (zh) | 2020-08-05 | 2023-09-29 | 辛德凯因股份有限公司 | Il27受体结合相关的组合物和方法 |
| WO2022032025A1 (en) * | 2020-08-05 | 2022-02-10 | Synthekine, Inc. | Ifngr binding synthetic cytokines and methods of use |
| JP7819178B2 (ja) | 2020-08-05 | 2026-02-24 | シンセカイン インコーポレイテッド | IL10Rb結合分子および使用方法 |
| WO2022067334A1 (en) * | 2020-09-25 | 2022-03-31 | The University Of Chicago | Anti-inflammatory cytokines and methods of use |
| CN112694532B (zh) * | 2021-01-12 | 2023-04-18 | 倍而达药业(苏州)有限公司 | 抗Siglec-15的抗体或其抗原结合片段及应用 |
| CN114316060B (zh) * | 2021-12-15 | 2023-06-13 | 北京市肿瘤防治研究所 | 抗人cd19与cd206双特异性抗体及其制备方法和应用 |
| FR3139339B1 (fr) * | 2022-09-01 | 2025-10-24 | Asfalia Biologics | Conjugués peptidiques et leur utilisation pour promouvoir l’immunotolérance aux nucleases cas dans une thérapie génique par ingenierie du genome |
| WO2024233853A2 (en) * | 2023-05-11 | 2024-11-14 | Elixiron Immunotherapeutics (hong Kong) Limited | A combination comprising lag-3 targeting moiety and interleukin-10 |
| WO2024249898A2 (en) * | 2023-06-02 | 2024-12-05 | Synthekine, Inc. | Fused il10 polypeptides |
| WO2025049885A1 (en) * | 2023-09-01 | 2025-03-06 | The Regents Of The University Of Michigan | Long-lived brain delivery of anti-inflammatory agents |
Family Cites Families (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| US3949064A (en) | 1973-10-26 | 1976-04-06 | Baxter Laboratories, Inc. | Method of detecting antigens or antibodies |
| US4174384A (en) | 1975-06-30 | 1979-11-13 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4554101A (en) | 1981-01-09 | 1985-11-19 | New York Blood Center, Inc. | Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity |
| CA2159639A1 (en) | 1993-04-02 | 1994-10-13 | Vincent J. Miles | Method for selective inactivation of viral replication |
| US20040258688A1 (en) | 1995-01-31 | 2004-12-23 | Daniel Hawiger | Enhanced antigen delivery and modulation of the immune response therefrom |
| AU726108B2 (en) | 1995-10-17 | 2000-11-02 | Genencor International, Inc. | Enzymatic array and process of making same |
| WO1997034634A1 (en) | 1996-03-20 | 1997-09-25 | Sloan-Kettering Institute For Cancer Research | Single chain fv constructs of anti-ganglioside gd2 antibodies |
| FR2748479A1 (fr) | 1996-05-10 | 1997-11-14 | Pasteur Institut | Polypeptide comportant un nouveau domaine cohesine de type ii, composition enzymatique en comportant et fragments d'adn codant pour ces polypeptides |
| US6046158A (en) | 1996-12-20 | 2000-04-04 | Board Of Regents The University Of Texas Systems | Unique dendritic cell-associated C-type lectins, dectin-1 and dectin-2; compositions and uses thereof |
| BR9811675A (pt) | 1997-07-09 | 2000-09-19 | Schering Corp | Genes isolados para proteìna da membrana de célula dentrìtica |
| US6777546B2 (en) | 1997-10-07 | 2004-08-17 | Loma Linda University | Methods and substances for preventing and treating autoimmune disease |
| US6541011B2 (en) | 1998-02-11 | 2003-04-01 | Maxygen, Inc. | Antigen library immunization |
| US5945308A (en) | 1998-04-03 | 1999-08-31 | Incyte Pharmaceuticals, Inc. | Human oxidized LDL receptor |
| JP2000157282A (ja) | 1998-11-30 | 2000-06-13 | Toyota Central Res & Dev Lab Inc | 酵素配列複合体及び固定化酵素配列複合体とそれらの製造方法、担体分子及び酵素 |
| CA2365981A1 (en) | 1999-03-24 | 2000-09-28 | Board Of Regents, The University Of Texas System | Linear and circular expression elements |
| EP1046651A1 (en) | 1999-04-19 | 2000-10-25 | Koninklijke Universiteit Nijmegen | Composition and method for modulating dendritic cell-T interaction |
| AU778207B2 (en) | 1999-04-21 | 2004-11-25 | Basf Aktiengesellschaft | Mixture of adipic or phthalic acid diesters and isomeric nonanols |
| JP5007007B2 (ja) * | 1999-11-15 | 2012-08-22 | ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング | 樹状細胞に特異的な抗原結合フラグメント、その組成物および使用方法、それによって認識される抗原およびそれによって得られる細胞 |
| AU784677B2 (en) | 2000-03-02 | 2006-05-25 | Abgenix, Inc. | Human monoclonal antibodies against oxidized LDL receptor and pharmaceutical uses thereof |
| US20060222633A1 (en) * | 2000-05-11 | 2006-10-05 | Yale University | Prevention, decrease, and/or treatment of immunoreactivity by depleting and/or inactivating antigen presenting cells in the host |
| FR2816060A1 (fr) | 2000-10-27 | 2002-05-03 | Pf Medicament | Procede d'identification de nouvelles molecules se liant au recepteur lox et utilisation de ces molecules |
| AU2002332598A1 (en) | 2001-08-22 | 2003-03-10 | Shengfeng Li | Compositions and methods for generating antigen-binding units |
| US20050106700A1 (en) | 2001-10-11 | 2005-05-19 | Tsuyoshi Nomura | Method of purifying recombinant fused protein and method of producing protein using the same |
| WO2003036895A1 (en) | 2001-10-25 | 2003-05-01 | Renesas Technology Corp. | Semiconductor integrated circuit for communication, modulating/demodulating device, and communication diagnosing method |
| AU2002363861A1 (en) | 2001-11-30 | 2003-06-10 | Crucell Holland B.V. | Antigen presenting cell targeting conjugate, an intigen presenting cell contacted with such conjugate, their use for vaccination or as medicament, and methods for their production or generation |
| AU2003213640A1 (en) | 2002-02-28 | 2003-09-16 | Corixa Corporation | Methods of modulating dendritic cells using adjuvants |
| US6738985B2 (en) | 2002-05-14 | 2004-05-25 | David S. Hahn | Disposable sweatband liner |
| US20040091503A1 (en) | 2002-08-20 | 2004-05-13 | Genitrix, Llc | Lectin compositions and methods for modulating an immune response to an antigen |
| JP2004236504A (ja) | 2003-02-03 | 2004-08-26 | Toyota Central Res & Dev Lab Inc | 酵素配列複合体及び固定化酵素配列複合体とそれらの製造方法、担体分子及び酵素 |
| EP1605974B1 (en) * | 2003-03-04 | 2014-11-12 | Alexion Pharmaceuticals, Inc. | Method of treating autoimmune disease by inducing antigen presentation by tolerance inducing antigen presenting cells |
| US20050064509A1 (en) | 2003-09-23 | 2005-03-24 | The Regents Of The University Of California | Use of templated self assembly to create novel multifunctional species |
| US20060019342A1 (en) | 2004-06-25 | 2006-01-26 | Medimmune, Inc. | Increasing the production of recombinant antibodies in mammalian cells by site-directed mutagenesis |
| CA2604032C (en) | 2005-04-06 | 2017-08-22 | Ibc Pharmaceuticals, Inc. | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses |
| US7666596B2 (en) | 2005-05-23 | 2010-02-23 | University Of Alberta | Tissue rejection |
| US7592003B2 (en) | 2005-09-30 | 2009-09-22 | Oklahoma Medical Research Foundation | Regulation of toll-like receptors on stem cells |
| GB0605735D0 (en) | 2006-03-22 | 2006-05-03 | Immunobiology Ltd | Composition and method for mediating an immune response |
| KR20090008467A (ko) | 2006-05-08 | 2009-01-21 | 필로겐 에스.피.에이. | 치료용의 항체표적 사이토카인 |
| TWI422594B (zh) * | 2007-02-02 | 2014-01-11 | Baylor Res Inst | 經由樹狀細胞去唾液酸糖蛋白受體(dc-asgpr)接合抗原呈現細胞之藥劑 |
| MX2009008140A (es) | 2007-02-02 | 2009-10-26 | Baylor Res Inst | Vacunas a base de antigeno dirigido a dcir expresado en celulas que presentan antigeno. |
| NZ578657A (en) | 2007-02-02 | 2012-02-24 | Baylor Res Inst | Multivariable antigens complexed with targeting humanized monoclonal antibody |
| EP2132226B1 (en) | 2007-02-23 | 2019-03-27 | Baylor Research Institute | Activation of human antigen-presenting cells through dendritic cell lectin-like oxidized ldl receptor-1 (lox-1) |
| CN101679949B (zh) | 2007-02-23 | 2015-08-19 | 贝勒研究院 | 通过dectin-1激活人抗原呈递细胞的治疗性应用 |
| FR2933816B1 (fr) * | 2008-07-10 | 2015-08-21 | Commissariat Energie Atomique | Dispositif a coupleur selectif en longueur d'onde pour collection de la lumiere emise par une source laser. |
| EP3281955A1 (en) | 2008-10-02 | 2018-02-14 | Aptevo Research and Development LLC | Cd86 antagonist multi-target binding proteins |
| CA2813494A1 (en) * | 2009-10-08 | 2011-04-14 | President And Fellows Of Harvard College | Methods and compositions for amelioration of autoimmune disease using fusion proteins of anti-dendritic cell receptor antibody to peptide sequences |
| CA2794499A1 (en) * | 2010-04-01 | 2011-10-06 | Immumomedics, Inc. | Antibody-based depletion of antigen-presenting cells and dendritic cells |
| MX2012012833A (es) | 2010-05-07 | 2012-11-30 | Baylor Res Inst | Cebado cruzado de celulas t cd8 positivas humanos moderada por inmunoreceptores de celulas dendriticas (dcir). |
| RU2013110889A (ru) | 2010-08-13 | 2014-09-20 | Бейлор Рисёч Инститьют | Новые вакцинные адъюванты на основе адъювантов-антител, нацеливающих непосредственно на антигенпрезентирующие клетки |
| AR083400A1 (es) * | 2010-10-13 | 2013-02-21 | Baylor Res Inst | Direccionamiento de los antigenos a las celulas dendriticas humanas a traves del receptor de asialoglicoproteinas dc para producir celulas t reguladoras con il-10 |
| US20120121592A1 (en) * | 2010-10-13 | 2012-05-17 | Baylor Research Institute | Targeting Antigens to Human Dendritic Cells Via DC-Asialoglycoprotein Receptor to Produce IL-10 Regulatory T-Cells |
| AU2011316777A1 (en) | 2010-10-22 | 2013-06-13 | University Of Florida Research Foundation, Inc. | Antigen-specific, tolerance-inducing microparticles and uses thereof |
| WO2012122396A1 (en) | 2011-03-08 | 2012-09-13 | Baylor Research Institute | Novel vaccine adjuvants based on targeting adjuvants to antibodies directly to antigen-presenting cells |
| WO2012129227A1 (en) | 2011-03-22 | 2012-09-27 | Baylor Research Institute | Dendritic cells (dcs) targeting for tuberculosis (tb) vaccine |
| TW201300418A (zh) | 2011-03-25 | 2013-01-01 | Baylor Res Inst | 用於抗c型肝炎病毒免疫之組合物及方法 |
| AR086287A1 (es) | 2011-05-05 | 2013-12-04 | Baylor Res Inst | Composicion inmunoestimulante, metodo |
| BR112015002085A2 (pt) | 2012-08-08 | 2017-12-19 | Roche Glycart Ag | proteína, polinucleotídeo, vetor, célula hospedeira, método para produzir a proteína, composição farmacêutica, uso da proteína, método de tratamento e invenção |
| US9771427B2 (en) * | 2012-08-09 | 2017-09-26 | Roche Glycart Ag | ASGPR antibodies and uses thereof |
| CA2916694C (en) * | 2013-06-28 | 2023-01-17 | Baylor Research Institute | Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis |
-
2015
- 2015-05-15 JP JP2017512873A patent/JP6836500B2/ja active Active
- 2015-05-15 US US15/311,572 patent/US10993990B2/en active Active
- 2015-05-15 CA CA3185180A patent/CA3185180A1/en active Pending
- 2015-05-15 AU AU2015258875A patent/AU2015258875B2/en active Active
- 2015-05-15 CA CA2949081A patent/CA2949081C/en active Active
- 2015-05-15 CN CN201580038844.8A patent/CN106659774A/zh active Pending
- 2015-05-15 WO PCT/US2015/031117 patent/WO2015175957A1/en not_active Ceased
- 2015-05-15 IL IL300029A patent/IL300029A/en unknown
- 2015-05-15 EP EP15792154.5A patent/EP3142691A4/en active Pending
-
2016
- 2016-11-08 IL IL248837A patent/IL248837B2/en unknown
-
2021
- 2021-02-05 JP JP2021017236A patent/JP7222004B2/ja active Active
- 2021-03-22 AU AU2021201773A patent/AU2021201773B2/en active Active
- 2021-03-25 US US17/301,123 patent/US11957734B2/en active Active
-
2023
- 2023-02-02 JP JP2023014370A patent/JP7663616B2/ja active Active
- 2023-12-14 AU AU2023282255A patent/AU2023282255B2/en active Active
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