JP2021054763A - 赤血球減少抑制剤、食品添加物及び飲食品 - Google Patents
赤血球減少抑制剤、食品添加物及び飲食品 Download PDFInfo
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- XRHHDQSPFPQKMS-UHFFFAOYSA-N Sudachitin Chemical compound C1=C(O)C(OC)=CC(C=2OC3=C(OC)C(O)=C(OC)C(O)=C3C(=O)C=2)=C1 XRHHDQSPFPQKMS-UHFFFAOYSA-N 0.000 claims abstract description 68
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- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 description 1
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Landscapes
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Non-Alcoholic Beverages (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
項1
スダチチンを含む、赤血球減少抑制剤。
項2
項1に記載の赤血球減少抑制剤を含む、食品添加物。
項3
項2に記載の食品添加物を含む、飲食品。
反応容器に、スダチ果皮3kg及び70質量%エタノール水溶液5Lを入れ、85℃で3時間攪拌したあと、ろ過および遠心分離を行うことにより残渣を取り除いて溶液を得た。続いて、溶液が1Lになるまで濃縮した後、スプレー乾燥を行なうことにより、スダチチンを1質量%含むスダチ果皮エキス末(残部はスダチチン以外のスダチ由来成分)を得た。
シクロデキストリン350mgをカプセルに封入することにより、スダチ果皮エキス末を含まないカプセルを得た。
実施例1で得られたスダチ果皮エキス末含有カプセル(試験品群)および比較例1で得られたスダチ果皮エキス末を含まないカプセル(対照品群)それぞれを摂取した場合において、摂取開始前から摂取4週後、8週後、及び摂取終了後(摂取12週間後)までの赤血球数(RBC)の変化を群内比較した。この試験において、摂取量は試験品又は対照品を1日1回3カプセルとし、摂取タイミングは、朝食時、昼食時、夕食時のうちいつでもよいとした。また、摂取方法は、1回3カプセル(3カプセル/包)を、そのままもしくは水又は湯と一緒に飲むこととした。試験品群はn=20、対照品群はn=18とした。
Claims (3)
- スダチチンを含む、赤血球減少抑制剤。
- 請求項1に記載の赤血球減少抑制剤を含む、食品添加物。
- 請求項2に記載の食品添加物を含む、飲食品。
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Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007077139A (ja) * | 2005-08-18 | 2007-03-29 | Univ Of Tokushima | スダチ由来の組成物、並びに当該組成物を含有する医薬組成物、健康飲食品及びサプリメント |
JP2009126799A (ja) * | 2007-11-21 | 2009-06-11 | Univ Of Tokushima | 新規nad依存性脱アセチル化酵素活性化剤 |
JP2013173718A (ja) * | 2012-02-27 | 2013-09-05 | Univ Of Tokushima | スダチチンを有効成分とする、エネルギー代謝改善剤 |
JP2017043581A (ja) * | 2015-08-28 | 2017-03-02 | 株式会社ファンケル | 神経細胞死抑制剤 |
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007077139A (ja) * | 2005-08-18 | 2007-03-29 | Univ Of Tokushima | スダチ由来の組成物、並びに当該組成物を含有する医薬組成物、健康飲食品及びサプリメント |
JP2009126799A (ja) * | 2007-11-21 | 2009-06-11 | Univ Of Tokushima | 新規nad依存性脱アセチル化酵素活性化剤 |
JP2013173718A (ja) * | 2012-02-27 | 2013-09-05 | Univ Of Tokushima | スダチチンを有効成分とする、エネルギー代謝改善剤 |
JP2017043581A (ja) * | 2015-08-28 | 2017-03-02 | 株式会社ファンケル | 神経細胞死抑制剤 |
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