JP2020536070A - 新規な塩 - Google Patents

新規な塩 Download PDF

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Publication number
JP2020536070A
JP2020536070A JP2020518078A JP2020518078A JP2020536070A JP 2020536070 A JP2020536070 A JP 2020536070A JP 2020518078 A JP2020518078 A JP 2020518078A JP 2020518078 A JP2020518078 A JP 2020518078A JP 2020536070 A JP2020536070 A JP 2020536070A
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JP
Japan
Prior art keywords
methyl
compound
formula
disorders
xrpd pattern
Prior art date
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JP2020518078A
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English (en)
Japanese (ja)
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JP2020536070A5 (enExample
Inventor
エム．ピー．ギブリン ジェラルド
エム．ピー．ギブリン ジェラルド
ティー．マクファーソン デイビッド
ティー．マクファーソン デイビッド
ウィリアムス マイケル
ウィリアムス マイケル
アール．ウィッティ デイビッド
アール．ウィッティ デイビッド
ノーザン ジュリアン
ノーザン ジュリアン
バスデバン カルヤン
バスデバン カルヤン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biogen Inc
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of JP2020536070A publication Critical patent/JP2020536070A/ja
Publication of JP2020536070A5 publication Critical patent/JP2020536070A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2020518078A 2017-09-28 2018-09-28 新規な塩 Withdrawn JP2020536070A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762564744P 2017-09-28 2017-09-28
US62/564,744 2017-09-28
PCT/US2018/053520 WO2019067961A1 (en) 2017-09-28 2018-09-28 NEW SALTS

Publications (2)

Publication Number Publication Date
JP2020536070A true JP2020536070A (ja) 2020-12-10
JP2020536070A5 JP2020536070A5 (enExample) 2021-11-25

Family

ID=65902742

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020518078A Withdrawn JP2020536070A (ja) 2017-09-28 2018-09-28 新規な塩

Country Status (14)

Country Link
US (1) US20200255438A1 (enExample)
EP (1) EP3687533A4 (enExample)
JP (1) JP2020536070A (enExample)
KR (1) KR20200060404A (enExample)
CN (1) CN111343978A (enExample)
AU (2) AU2018338884A1 (enExample)
BR (1) BR112020005992A2 (enExample)
CA (1) CA3074923A1 (enExample)
EA (1) EA202090853A1 (enExample)
IL (1) IL273520A (enExample)
MA (1) MA50669A (enExample)
MX (1) MX2020003741A (enExample)
SG (1) SG11202002200UA (enExample)
WO (1) WO2019067961A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3077088A1 (en) 2017-10-10 2019-04-18 Biogen Inc. Process for preparing spiro derivatives

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015517561A (ja) * 2012-05-22 2015-06-22 クオンベルゲンセ プハルマセウトイカルス リミテッド 新規化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2789711C (en) * 2010-02-17 2014-08-05 Amgen Inc. Aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain
EA201491990A1 (ru) * 2012-05-03 2015-02-27 Новартис Аг L-малатная соль 2,7-диазаспиро[4.5]дец-7-иловых производных и их кристаллические формы в качестве агонистов грелиновых рецепторов

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015517561A (ja) * 2012-05-22 2015-06-22 クオンベルゲンセ プハルマセウトイカルス リミテッド 新規化合物

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
川口洋子ら: "医薬品と結晶多形", 生活工学研究, vol. 4, no. 2, JPN6014015069, 2002, pages 310 - 317, ISSN: 0004854402 *
平山令明, 有機化合物結晶作製ハンドブック, JPN6014035600, 2008, pages 17 - 23, ISSN: 0004854401 *
芦澤一英, 医薬品の多形現象と晶析の化学, JPN6015027444, 2002, pages 273 - 278, ISSN: 0005038718 *

Also Published As

Publication number Publication date
AU2023202293A1 (en) 2023-05-11
EP3687533A4 (en) 2021-01-20
MA50669A (fr) 2020-08-05
AU2018338884A1 (en) 2020-04-16
IL273520A (en) 2020-05-31
KR20200060404A (ko) 2020-05-29
SG11202002200UA (en) 2020-04-29
MX2020003741A (es) 2021-01-08
CA3074923A1 (en) 2019-04-04
BR112020005992A2 (pt) 2020-09-29
US20200255438A1 (en) 2020-08-13
EA202090853A1 (ru) 2020-08-27
CN111343978A (zh) 2020-06-26
WO2019067961A1 (en) 2019-04-04
EP3687533A1 (en) 2020-08-05

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