KR20200060404A - 신규한 염 - Google Patents

신규한 염 Download PDF

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Publication number
KR20200060404A
KR20200060404A KR1020207009445A KR20207009445A KR20200060404A KR 20200060404 A KR20200060404 A KR 20200060404A KR 1020207009445 A KR1020207009445 A KR 1020207009445A KR 20207009445 A KR20207009445 A KR 20207009445A KR 20200060404 A KR20200060404 A KR 20200060404A
Authority
KR
South Korea
Prior art keywords
compound
methyl
salt
formula
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020207009445A
Other languages
English (en)
Korean (ko)
Inventor
제랄드 엠.피. 기블린
데이비드 티. 맥퍼슨
마이클 윌리엄스
데이비드 알. 위티
줄리안 노르덴
칼리안 바수데반
Original Assignee
바이오젠 인크.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 바이오젠 인크. filed Critical 바이오젠 인크.
Publication of KR20200060404A publication Critical patent/KR20200060404A/ko
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020207009445A 2017-09-28 2018-09-28 신규한 염 Withdrawn KR20200060404A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762564744P 2017-09-28 2017-09-28
US62/564,744 2017-09-28
PCT/US2018/053520 WO2019067961A1 (en) 2017-09-28 2018-09-28 NEW SALTS

Publications (1)

Publication Number Publication Date
KR20200060404A true KR20200060404A (ko) 2020-05-29

Family

ID=65902742

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207009445A Withdrawn KR20200060404A (ko) 2017-09-28 2018-09-28 신규한 염

Country Status (14)

Country Link
US (1) US20200255438A1 (enExample)
EP (1) EP3687533A4 (enExample)
JP (1) JP2020536070A (enExample)
KR (1) KR20200060404A (enExample)
CN (1) CN111343978A (enExample)
AU (2) AU2018338884A1 (enExample)
BR (1) BR112020005992A2 (enExample)
CA (1) CA3074923A1 (enExample)
EA (1) EA202090853A1 (enExample)
IL (1) IL273520A (enExample)
MA (1) MA50669A (enExample)
MX (1) MX2020003741A (enExample)
SG (1) SG11202002200UA (enExample)
WO (1) WO2019067961A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020536898A (ja) 2017-10-10 2020-12-17 バイオジェン インコーポレイテッド スピロ誘導体を調製するためのプロセス

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011103196A1 (en) * 2010-02-17 2011-08-25 Amgen Inc. Aryl carboxamide derivatives as sodium channel inhibitors for treatment of pain
EA201491990A1 (ru) * 2012-05-03 2015-02-27 Новартис Аг L-малатная соль 2,7-диазаспиро[4.5]дец-7-иловых производных и их кристаллические формы в качестве агонистов грелиновых рецепторов
GB201209015D0 (en) * 2012-05-22 2012-07-04 Convergence Pharmaceuticals Novel compounds

Also Published As

Publication number Publication date
CA3074923A1 (en) 2019-04-04
BR112020005992A2 (pt) 2020-09-29
IL273520A (en) 2020-05-31
US20200255438A1 (en) 2020-08-13
EP3687533A1 (en) 2020-08-05
CN111343978A (zh) 2020-06-26
MA50669A (fr) 2020-08-05
AU2023202293A1 (en) 2023-05-11
SG11202002200UA (en) 2020-04-29
JP2020536070A (ja) 2020-12-10
EP3687533A4 (en) 2021-01-20
EA202090853A1 (ru) 2020-08-27
MX2020003741A (es) 2021-01-08
WO2019067961A1 (en) 2019-04-04
AU2018338884A1 (en) 2020-04-16

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A201 Request for examination
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St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

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PC1202 Submission of document of withdrawal before decision of registration

St.27 status event code: N-1-6-B10-B11-nap-PC1202