JP2020533373A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020533373A5 JP2020533373A5 JP2020515070A JP2020515070A JP2020533373A5 JP 2020533373 A5 JP2020533373 A5 JP 2020533373A5 JP 2020515070 A JP2020515070 A JP 2020515070A JP 2020515070 A JP2020515070 A JP 2020515070A JP 2020533373 A5 JP2020533373 A5 JP 2020533373A5
- Authority
- JP
- Japan
- Prior art keywords
- mca
- msc
- subject
- asthma
- mir
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000006673 asthma Diseases 0.000 claims 7
- 229940125388 beta agonist Drugs 0.000 claims 3
- 239000003246 corticosteroid Substances 0.000 claims 3
- 229960001334 corticosteroids Drugs 0.000 claims 3
- 208000023504 respiratory system disease Diseases 0.000 claims 3
- 102000008186 Collagen Human genes 0.000 claims 2
- 108010035532 Collagen Proteins 0.000 claims 2
- 102000009618 Transforming Growth Factors Human genes 0.000 claims 2
- 108010009583 Transforming Growth Factors Proteins 0.000 claims 2
- 229920001436 collagen Polymers 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 claims 2
- 230000002685 pulmonary effect Effects 0.000 claims 2
- 102100022464 5'-nucleotidase Human genes 0.000 claims 1
- 102100032912 CD44 antigen Human genes 0.000 claims 1
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 1
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 101000678236 Homo sapiens 5'-nucleotidase Proteins 0.000 claims 1
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 claims 1
- 101000738771 Homo sapiens Receptor-type tyrosine-protein phosphatase C Proteins 0.000 claims 1
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 102000002274 Matrix Metalloproteinases Human genes 0.000 claims 1
- 102000003729 Neprilysin Human genes 0.000 claims 1
- 108090000028 Neprilysin Proteins 0.000 claims 1
- 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 1
- 102100037422 Receptor-type tyrosine-protein phosphatase C Human genes 0.000 claims 1
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 claims 1
- 208000028004 allergic respiratory disease Diseases 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000001332 colony forming effect Effects 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 210000002175 goblet cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 210000001704 mesoblast Anatomy 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 108091091207 miR-127 stem-loop Proteins 0.000 claims 1
- 108091074194 miR-181b-1 stem-loop Proteins 0.000 claims 1
- 108091038599 miR-181b-2 stem-loop Proteins 0.000 claims 1
- 108091061809 miR-181b-3 stem-loop Proteins 0.000 claims 1
- 108091026331 miR-214 stem-loop Proteins 0.000 claims 1
- 108091048888 miR-214-1 stem-loop Proteins 0.000 claims 1
- 108091078347 miR-214-2 stem-loop Proteins 0.000 claims 1
- 108091035552 miR-214-3 stem-loop Proteins 0.000 claims 1
- 108091070501 miRNA Proteins 0.000 claims 1
- 210000000651 myofibroblast Anatomy 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 208000005069 pulmonary fibrosis Diseases 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 230000008719 thickening Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2017903758A AU2017903758A0 (en) | 2017-09-15 | Method | |
| AU2017903758 | 2017-09-15 | ||
| PCT/AU2018/050937 WO2019051536A1 (en) | 2017-09-15 | 2018-08-31 | METHOD OF TREATING ALLERGIC RESPIRATORY TRACT DISEASE (DAA) / ASTHMA |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020533373A JP2020533373A (ja) | 2020-11-19 |
| JP2020533373A5 true JP2020533373A5 (enExample) | 2021-10-14 |
Family
ID=65722228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020515070A Pending JP2020533373A (ja) | 2017-09-15 | 2018-08-31 | アレルギー性気道疾患（ａａｄ）／喘息の処置方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11471493B2 (enExample) |
| EP (1) | EP3681519B1 (enExample) |
| JP (1) | JP2020533373A (enExample) |
| KR (1) | KR20200053501A (enExample) |
| CN (1) | CN111093680A (enExample) |
| AR (1) | AR112802A1 (enExample) |
| AU (1) | AU2018333272B2 (enExample) |
| BR (1) | BR112020004856A2 (enExample) |
| CA (1) | CA3074470C (enExample) |
| ES (1) | ES2996339T3 (enExample) |
| MX (1) | MX2020002760A (enExample) |
| SG (1) | SG11202001909TA (enExample) |
| TW (1) | TWI806896B (enExample) |
| WO (1) | WO2019051536A1 (enExample) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100785969B1 (ko) * | 2004-05-12 | 2007-12-14 | 동아제약주식회사 | Ｆｇｆ2를 유효성분으로 포함하는 천식 및 만성폐쇄성폐질환 예방 또는 치료제 |
| AU2011343736A1 (en) * | 2010-12-17 | 2013-05-02 | Anthrogenesis Corporation | Treatment of immune-related diseases and disorders using amnion derived adherent cells |
| RU2018128383A (ru) * | 2012-03-07 | 2019-03-14 | Янссен Байотек, Инк. | Среда определенного состава для размножения и обновления плюрипотентных стволовых клеток |
| US20150064141A1 (en) * | 2012-04-05 | 2015-03-05 | The Regents Of The University Of California | Regenerative sera cells and mesenchymal stem cells |
| WO2013159091A2 (en) * | 2012-04-20 | 2013-10-24 | Aptamir Therapeutics, Inc. | Mirna modulators of thermogenesis |
| CN104471059B (zh) * | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| ES2813407T3 (es) * | 2012-08-06 | 2021-03-23 | Brainstorm Cell Therapeutics Ltd | Métodos para generar células madre mesenquimales que secretan factores neurotróficos |
| EP2931373B1 (en) * | 2012-12-12 | 2019-08-21 | Mesoblast, Inc. | Methods of treating or preventing respiratory conditions |
| CA3141731A1 (en) | 2013-03-13 | 2014-10-09 | Wisconsin Alumni Research Foundation | Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions |
| EP3233097A4 (en) * | 2014-12-19 | 2018-08-08 | Cell Ideas Pty Ltd. | Improved cell therapies |
| CA3017772C (en) | 2016-03-16 | 2023-02-21 | Cynata Therapeutics Limited | Colony forming medium and use thereof |
| WO2018023170A1 (en) * | 2016-08-04 | 2018-02-08 | Hudson Institute of Medical Research | A method of treatment |
| AU2018285953A1 (en) | 2017-06-16 | 2020-01-16 | Cynata Therapeutics Limited | Method for treating a side effect of immunotherapy |
-
2018
- 2018-08-31 BR BR112020004856-9A patent/BR112020004856A2/pt unknown
- 2018-08-31 JP JP2020515070A patent/JP2020533373A/ja active Pending
- 2018-08-31 KR KR1020207007796A patent/KR20200053501A/ko not_active Ceased
- 2018-08-31 WO PCT/AU2018/050937 patent/WO2019051536A1/en not_active Ceased
- 2018-08-31 ES ES18855341T patent/ES2996339T3/es active Active
- 2018-08-31 MX MX2020002760A patent/MX2020002760A/es unknown
- 2018-08-31 CN CN201880059290.3A patent/CN111093680A/zh active Pending
- 2018-08-31 EP EP18855341.6A patent/EP3681519B1/en active Active
- 2018-08-31 US US16/646,041 patent/US11471493B2/en active Active
- 2018-08-31 AU AU2018333272A patent/AU2018333272B2/en active Active
- 2018-08-31 CA CA3074470A patent/CA3074470C/en active Active
- 2018-08-31 SG SG11202001909TA patent/SG11202001909TA/en unknown
- 2018-09-10 TW TW107131786A patent/TWI806896B/zh active
- 2018-09-13 AR ARP180102599A patent/AR112802A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104781394B (zh) | 用于培养间充质干细胞的方法 | |
| RU2014150508A (ru) | МОДУЛЯЦИЯ hUTC ПРОВОСПАЛИТЕЛЬНЫХ МЕДИАТОРОВ ЛЕГОЧНЫХ И ПУЛЬМОНАЛЬНЫХ ЗАБОЛЕВАНИЙ И РАССТРОЙСТВ | |
| JP2014522833A5 (enExample) | ||
| JP2023090901A (ja) | 免疫疾患の治療 | |
| RU2015143254A (ru) | Лечение заболеваний, расстройств или патологических состояний легких с использованием плацентарных клеток | |
| WO2014075593A1 (zh) | 间充质干细胞注射液及其制备方法和在制备治疗溃疡性结肠炎药物中的应用 | |
| JP2010527988A5 (enExample) | ||
| RU2017124983A (ru) | Лечение дегенерации сетчатки с использованием клеток-предшественников | |
| Li et al. | Hepatocyte growth factor gene-modified mesenchymal stem cells augment sinonasal wound healing | |
| JP2023520233A (ja) | 間葉系統前駆細胞又は幹細胞を使用する過炎症の治療方法 | |
| JP2019532081A (ja) | ヒストン脱アセチル化阻害剤及びプライミング因子を有効成分として含む幹細胞活性促進用組成物 | |
| Coppolino et al. | Role of stem cells in the pathogenesis of chronic obstructive pulmonary disease and pulmonary emphysema | |
| Ee et al. | The therapeutic potential of stem cells for bronchopulmonary dysplasia:“it’s about time” or “not so fast”? | |
| US20220273725A1 (en) | Therapeutic drugs for fibrosis, inflammation, and/or aging diseases | |
| JP2020533373A5 (enExample) | ||
| Murphy et al. | Cell therapy for cystic fibrosis | |
| JP2011015609A (ja) | 内皮前駆細胞（ｅｐｃ）の増殖・分化誘導方法 | |
| Chen et al. | Current state of heart failure treatment: are mesenchymal stem cells and their exosomes a future therapy? | |
| EP2931876B1 (en) | Treatment of diseases of endothelial dysfunction and inflammation | |
| RU2020111190A (ru) | Способ лечения аллергического заболевания дыхательных путей (AAD)/астмы | |
| Alphonse et al. | Growth factors, stem cells and bronchopulmonary dysplasia | |
| CN113025563B (zh) | 诱导气道基底干细胞分化为支气管肺泡干细胞的培养基和方法 | |
| WO2020014594A8 (en) | Compositions for the treatment of copper deficiency and methods of use | |
| Wang et al. | The Mechanism of MSCs Therapy in Acute Respiratory Distress Syndrome | |
| Ishii | Stem Cell Therapy and Regenerative |