AR112802A1 - Método para tratar enfermedades alérgicas de las vías aéreas (aad) / asma - Google Patents
Método para tratar enfermedades alérgicas de las vías aéreas (aad) / asmaInfo
- Publication number
- AR112802A1 AR112802A1 ARP180102599A ARP180102599A AR112802A1 AR 112802 A1 AR112802 A1 AR 112802A1 AR P180102599 A ARP180102599 A AR P180102599A AR P180102599 A ARP180102599 A AR P180102599A AR 112802 A1 AR112802 A1 AR 112802A1
- Authority
- AR
- Argentina
- Prior art keywords
- mir
- mca
- msc
- mesenchymal
- daa
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 208000028004 allergic respiratory disease Diseases 0.000 title abstract 3
- 208000006673 asthma Diseases 0.000 title abstract 3
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 abstract 2
- 210000002901 mesenchymal stem cell Anatomy 0.000 abstract 2
- 108091091207 miR-127 stem-loop Proteins 0.000 abstract 2
- 108091053592 miR-145-1 stem-loop Proteins 0.000 abstract 2
- 108091056559 miR-145-2 stem-loop Proteins 0.000 abstract 2
- 108091074194 miR-181b-1 stem-loop Proteins 0.000 abstract 2
- 108091038599 miR-181b-2 stem-loop Proteins 0.000 abstract 2
- 108091061809 miR-181b-3 stem-loop Proteins 0.000 abstract 2
- 108091026331 miR-214 stem-loop Proteins 0.000 abstract 2
- 108091048888 miR-214-1 stem-loop Proteins 0.000 abstract 2
- 108091078347 miR-214-2 stem-loop Proteins 0.000 abstract 2
- 108091035552 miR-214-3 stem-loop Proteins 0.000 abstract 2
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 abstract 1
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000005757 colony formation Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0668—Mesenchymal stem cells from other natural sources
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/069—Vascular Endothelial cells
- C12N5/0692—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2511/00—Cells for large scale production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2017903758A AU2017903758A0 (en) | 2017-09-15 | Method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR112802A1 true AR112802A1 (es) | 2019-12-11 |
Family
ID=65722228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180102599A AR112802A1 (es) | 2017-09-15 | 2018-09-13 | Método para tratar enfermedades alérgicas de las vías aéreas (aad) / asma |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11471493B2 (enExample) |
| EP (1) | EP3681519B1 (enExample) |
| JP (1) | JP2020533373A (enExample) |
| KR (1) | KR20200053501A (enExample) |
| CN (1) | CN111093680A (enExample) |
| AR (1) | AR112802A1 (enExample) |
| AU (1) | AU2018333272B2 (enExample) |
| BR (1) | BR112020004856A2 (enExample) |
| CA (1) | CA3074470C (enExample) |
| ES (1) | ES2996339T3 (enExample) |
| MX (1) | MX2020002760A (enExample) |
| SG (1) | SG11202001909TA (enExample) |
| TW (1) | TWI806896B (enExample) |
| WO (1) | WO2019051536A1 (enExample) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100785969B1 (ko) * | 2004-05-12 | 2007-12-14 | 동아제약주식회사 | Ｆｇｆ2를 유효성분으로 포함하는 천식 및 만성폐쇄성폐질환 예방 또는 치료제 |
| US20120164114A1 (en) * | 2010-12-17 | 2012-06-28 | Abbot Stewart | Treatment of immune-related diseases and disorders using amnion derived adherent cells |
| EP2823037A4 (en) * | 2012-03-07 | 2015-09-16 | Janssen Biotech Inc | DEFINED MEDIA FOR THE EXPANSION AND CARE OF PLURIPOTENTAL STEM CELLS |
| US20150064141A1 (en) * | 2012-04-05 | 2015-03-05 | The Regents Of The University Of California | Regenerative sera cells and mesenchymal stem cells |
| JP2015518485A (ja) * | 2012-04-20 | 2015-07-02 | アプタミアール セラピューティクス インコーポレイテッド | 熱発生のｍｉＲＮＡ調節剤 |
| WO2014011407A2 (en) * | 2012-07-12 | 2014-01-16 | Imstem Biotechnology, Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| US10046010B2 (en) * | 2012-08-06 | 2018-08-14 | Brainstorm Cell Therapeutics Ltd. | Methods of generating mesenchymal stem cells which secrete neurotrophic factors |
| ES2759281T3 (es) * | 2012-12-12 | 2020-05-08 | Mesoblast Inc | Métodos de tratamiento o prevención de afecciones respiratorias |
| PT2970912T (pt) | 2013-03-13 | 2019-05-31 | Wisconsin Alumni Res Found | Métodos e materiais para a diferenciação hematoendotelial de células estaminais pluripotentes humanas em condições definidas |
| AU2015367275B2 (en) * | 2014-12-19 | 2021-11-18 | Cell Ideas Pty Ltd | Improved cell therapies |
| RU2756561C2 (ru) * | 2016-03-16 | 2021-10-01 | Сината Терапьютикс Лимитед | Среда для формирования колоний и её применение |
| EP3493821A4 (en) * | 2016-08-04 | 2020-04-08 | Hudson Institute of Medical Research | METHOD OF TREATING THE RESPIRATORY TRACT |
| JP2020523400A (ja) | 2017-06-16 | 2020-08-06 | サイナータ セラピューティクス リミテッド | 免疫療法の副作用を治療するための方法 |
-
2018
- 2018-08-31 CA CA3074470A patent/CA3074470C/en active Active
- 2018-08-31 CN CN201880059290.3A patent/CN111093680A/zh active Pending
- 2018-08-31 SG SG11202001909TA patent/SG11202001909TA/en unknown
- 2018-08-31 MX MX2020002760A patent/MX2020002760A/es unknown
- 2018-08-31 BR BR112020004856-9A patent/BR112020004856A2/pt unknown
- 2018-08-31 KR KR1020207007796A patent/KR20200053501A/ko not_active Ceased
- 2018-08-31 WO PCT/AU2018/050937 patent/WO2019051536A1/en not_active Ceased
- 2018-08-31 AU AU2018333272A patent/AU2018333272B2/en active Active
- 2018-08-31 JP JP2020515070A patent/JP2020533373A/ja active Pending
- 2018-08-31 ES ES18855341T patent/ES2996339T3/es active Active
- 2018-08-31 EP EP18855341.6A patent/EP3681519B1/en active Active
- 2018-08-31 US US16/646,041 patent/US11471493B2/en active Active
- 2018-09-10 TW TW107131786A patent/TWI806896B/zh active
- 2018-09-13 AR ARP180102599A patent/AR112802A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW201919666A (zh) | 2019-06-01 |
| US11471493B2 (en) | 2022-10-18 |
| MX2020002760A (es) | 2020-07-20 |
| ES2996339T3 (en) | 2025-02-12 |
| JP2020533373A (ja) | 2020-11-19 |
| WO2019051536A1 (en) | 2019-03-21 |
| BR112020004856A2 (pt) | 2020-09-15 |
| RU2020111190A (ru) | 2021-10-15 |
| CN111093680A (zh) | 2020-05-01 |
| EP3681519A4 (en) | 2021-04-28 |
| KR20200053501A (ko) | 2020-05-18 |
| TWI806896B (zh) | 2023-07-01 |
| RU2020111190A3 (enExample) | 2022-03-30 |
| US20200276243A1 (en) | 2020-09-03 |
| CA3074470A1 (en) | 2019-03-21 |
| SG11202001909TA (en) | 2020-04-29 |
| AU2018333272B2 (en) | 2022-12-08 |
| EP3681519A1 (en) | 2020-07-22 |
| CA3074470C (en) | 2024-01-16 |
| EP3681519B1 (en) | 2024-10-30 |
| AU2018333272A1 (en) | 2020-03-05 |
| EP3681519C0 (en) | 2024-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |