JP2020531531A5 - - Google Patents
Info
- Publication number
- JP2020531531A5 JP2020531531A5 JP2020511371A JP2020511371A JP2020531531A5 JP 2020531531 A5 JP2020531531 A5 JP 2020531531A5 JP 2020511371 A JP2020511371 A JP 2020511371A JP 2020511371 A JP2020511371 A JP 2020511371A JP 2020531531 A5 JP2020531531 A5 JP 2020531531A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- alkyl
- group
- trisubstituted
- disubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17187101.5 | 2017-08-21 | ||
| EP17187101 | 2017-08-21 | ||
| PCT/EP2018/072398 WO2019038215A1 (en) | 2017-08-21 | 2018-08-20 | BENZIMIDAZOLE DERIVATIVES AS ADENOSINE RECEPTOR ANTAGONISTS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020531531A JP2020531531A (ja) | 2020-11-05 |
| JP2020531531A5 true JP2020531531A5 (enExample) | 2023-02-02 |
| JP7287952B2 JP7287952B2 (ja) | 2023-06-06 |
Family
ID=59677148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020511371A Active JP7287952B2 (ja) | 2017-08-21 | 2018-08-20 | アデノシン受容体アンタゴニストとしてのベンズイミダゾール誘導体 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11453647B2 (enExample) |
| EP (1) | EP3672952B1 (enExample) |
| JP (1) | JP7287952B2 (enExample) |
| KR (1) | KR20200043433A (enExample) |
| CN (1) | CN110997662B (enExample) |
| AU (1) | AU2018320673B2 (enExample) |
| BR (1) | BR112020003594A2 (enExample) |
| CA (1) | CA3073333A1 (enExample) |
| ES (1) | ES2940408T3 (enExample) |
| IL (1) | IL272637B2 (enExample) |
| SG (1) | SG11202001337XA (enExample) |
| TW (1) | TWI791593B (enExample) |
| WO (1) | WO2019038215A1 (enExample) |
| ZA (1) | ZA202001780B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11497752B2 (en) | 2018-01-30 | 2022-11-15 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| US12509453B2 (en) | 2019-01-29 | 2025-12-30 | Foghorn Therapeutics Inc. | BRM/BRG1 inhibitors and uses thereof |
| WO2021155264A1 (en) * | 2020-01-29 | 2021-08-05 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| AU2021213811A1 (en) | 2020-01-29 | 2022-07-28 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| US11618751B1 (en) | 2022-03-25 | 2023-04-04 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives |
| US20240116897A1 (en) * | 2021-01-29 | 2024-04-11 | Korea Research Institute Of Chemical Technology | Benzothiazole and benzimidazole derivatives, pharmaceutically acceptable salt thereof, preparation method therefor, and pharmaceutical composition comprising same as active ingredient |
| US12606553B2 (en) | 2021-03-09 | 2026-04-21 | Foghorn Therapeutics Inc. | Crystalline forms, compositions containing same, and methods of their use |
| US11319319B1 (en) | 2021-04-07 | 2022-05-03 | Ventus Therapeutics U.S., Inc. | Compounds for inhibiting NLRP3 and uses thereof |
| EP4351640A1 (en) | 2021-06-07 | 2024-04-17 | Ares Trading S.A. | Combination treatment of cancer |
| US12331048B2 (en) | 2022-10-31 | 2025-06-17 | Ventus Therapeutics U.S., Inc. | Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors |
| AU2024271907A1 (en) * | 2023-05-15 | 2025-12-11 | Wigen Biomedicine Technology (shanghai) Co., Ltd. | Hdac1/2 selective inhibitor and use thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4207554A (en) | 1972-08-04 | 1980-06-10 | Med-El Inc. | Method and apparatus for automated classification and analysis of cells |
| US4125828A (en) | 1972-08-04 | 1978-11-14 | Med-El Inc. | Method and apparatus for automated classification and analysis of cells |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| DE69720965T2 (de) | 1996-02-13 | 2004-02-05 | Astrazeneca Ab | Chinazolinderivate und deren verwendung als vegf hemmer |
| NZ331191A (en) | 1996-03-05 | 2000-03-27 | Zeneca Ltd | 4-anilinoquinazoline derivatives and pharmaceutical compositions thereof |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| AU1688599A (en) | 1998-01-05 | 1999-07-26 | Eisai Co. Ltd. | Purine derivatives and adenosine a2 receptor antagonists serving as preventives/remedies for diabetes |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| US6841549B1 (en) | 1999-07-02 | 2005-01-11 | Eisai Co., Ltd. | Condensed imidazole compounds and a therapeutic agent for diabetes mellitus |
| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| MXPA02012905A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como agentes de dano vascular.. |
| MXPA02012903A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como inhibidores de angiogenesis. |
| WO2004089942A2 (en) | 2001-10-02 | 2004-10-21 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| EP1465634B1 (en) | 2001-12-12 | 2014-10-22 | The Government of the United States of America, as represented by the Secretary Department of Health and Human Services | Methods for using adenosine receptor inhibitors to enhance immune response and inflammation |
| US20080070932A1 (en) | 2003-04-09 | 2008-03-20 | Chi Vu | Triazolo[ 1,5-A] Pyrimidines And Pyrazolo[ 1,5-A] Pyrimidines And Methods Of Making And Using The Same |
| KR100710453B1 (ko) | 2003-05-13 | 2007-04-24 | 에프. 호프만-라 로슈 아게 | 아데노신 수용체 리간드로서의 2-이미다조-벤조싸이아졸 |
| PT1636223E (pt) | 2003-05-19 | 2008-05-06 | F Hoffmann-La Roche Ag | Derivados de benzotiazole como ligandos de receptores da adenosina |
| MXPA05012369A (es) | 2003-05-21 | 2006-02-02 | Hoffmann La Roche | Derivados de benzotiazol y uso de los mismos en el tratamiento de enfermedades relacionadas con el receptor a2a de adenosina. |
| RU2006112847A (ru) | 2003-09-19 | 2007-11-10 | Ф. Хоффманн-Ля Рош Аг (Ch) | Производные тиазолопиридина в качестве лигандов аденозинового рецептора |
| RS50574B (sr) | 2004-05-24 | 2010-05-07 | F. Hoffmann-La Roche Ag. | (4-metoksi-7-morfolin-4-il-benzotiazol-2-il)-amid 4-hidroksi-4-metil-piperidin-1-karboksilne kiseline |
| JP5202946B2 (ja) | 2004-07-22 | 2013-06-05 | エフ．ホフマン−ラ ロシュ アーゲー | ベンゾチアゾール誘導体 |
| US20060223849A1 (en) * | 2005-03-14 | 2006-10-05 | Mjalli Adnan M | Benzazole derivatives, compositions, and methods of use as beta-secretase inhibitors |
| CN102731488A (zh) * | 2011-04-02 | 2012-10-17 | 中国医学科学院药物研究所 | 苯并咪唑类衍生物、及其制法和药物组合物与用途 |
-
2018
- 2018-08-20 TW TW107128915A patent/TWI791593B/zh not_active IP Right Cessation
- 2018-08-20 KR KR1020207007994A patent/KR20200043433A/ko not_active Ceased
- 2018-08-20 EP EP18753209.8A patent/EP3672952B1/en active Active
- 2018-08-20 AU AU2018320673A patent/AU2018320673B2/en not_active Ceased
- 2018-08-20 IL IL272637A patent/IL272637B2/en unknown
- 2018-08-20 CN CN201880054520.7A patent/CN110997662B/zh active Active
- 2018-08-20 BR BR112020003594-7A patent/BR112020003594A2/pt not_active Application Discontinuation
- 2018-08-20 SG SG11202001337XA patent/SG11202001337XA/en unknown
- 2018-08-20 WO PCT/EP2018/072398 patent/WO2019038215A1/en not_active Ceased
- 2018-08-20 CA CA3073333A patent/CA3073333A1/en active Pending
- 2018-08-20 JP JP2020511371A patent/JP7287952B2/ja active Active
- 2018-08-20 ES ES18753209T patent/ES2940408T3/es active Active
- 2018-08-20 US US16/640,490 patent/US11453647B2/en active Active
-
2020
- 2020-03-20 ZA ZA2020/01780A patent/ZA202001780B/en unknown
-
2022
- 2022-03-14 US US17/693,527 patent/US20220306588A1/en active Pending
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