JP2020530844A5 - - Google Patents
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- JP2020530844A5 JP2020530844A5 JP2020508022A JP2020508022A JP2020530844A5 JP 2020530844 A5 JP2020530844 A5 JP 2020530844A5 JP 2020508022 A JP2020508022 A JP 2020508022A JP 2020508022 A JP2020508022 A JP 2020508022A JP 2020530844 A5 JP2020530844 A5 JP 2020530844A5
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023042770A JP2023082028A (ja) | 2017-08-14 | 2023-03-17 | Setd2を阻害することにより癌を処置する方法 |
| JP2025050879A JP2025094223A (ja) | 2017-08-14 | 2025-03-26 | Setd2を阻害することにより癌を処置する方法 |
Applications Claiming Priority (3)
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| US201762545353P | 2017-08-14 | 2017-08-14 | |
| US62/545,353 | 2017-08-14 | ||
| PCT/US2018/046698 WO2019036466A1 (en) | 2017-08-14 | 2018-08-14 | METHODS OF TREATING CANCER BY INHIBITING SETD2 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023042770A Division JP2023082028A (ja) | 2017-08-14 | 2023-03-17 | Setd2を阻害することにより癌を処置する方法 |
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| Publication Number | Publication Date |
|---|---|
| JP2020530844A JP2020530844A (ja) | 2020-10-29 |
| JP2020530844A5 true JP2020530844A5 (https=) | 2021-09-16 |
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020508022A Pending JP2020530844A (ja) | 2017-08-14 | 2018-08-14 | Setd2を阻害することにより癌を処置する方法 |
| JP2023042770A Pending JP2023082028A (ja) | 2017-08-14 | 2023-03-17 | Setd2を阻害することにより癌を処置する方法 |
| JP2025050879A Pending JP2025094223A (ja) | 2017-08-14 | 2025-03-26 | Setd2を阻害することにより癌を処置する方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023042770A Pending JP2023082028A (ja) | 2017-08-14 | 2023-03-17 | Setd2を阻害することにより癌を処置する方法 |
| JP2025050879A Pending JP2025094223A (ja) | 2017-08-14 | 2025-03-26 | Setd2を阻害することにより癌を処置する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US11952572B2 (https=) |
| EP (1) | EP3669279A4 (https=) |
| JP (3) | JP2020530844A (https=) |
| KR (1) | KR20200052294A (https=) |
| CN (2) | CN119405809A (https=) |
| AU (2) | AU2018318988A1 (https=) |
| CA (1) | CA3072746A1 (https=) |
| EA (1) | EA202090485A1 (https=) |
| IL (1) | IL272379B2 (https=) |
| MX (1) | MX2020001759A (https=) |
| SG (1) | SG11202000839TA (https=) |
| WO (1) | WO2019036466A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020530844A (ja) | 2017-08-14 | 2020-10-29 | エピザイム,インコーポレイティド | Setd2を阻害することにより癌を処置する方法 |
| CN112585119A (zh) | 2018-08-14 | 2021-03-30 | Epizyme股份有限公司 | 经取代的吲哚及其使用方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL63907A0 (en) | 1980-09-24 | 1981-12-31 | Cetus Corp | Diagnostic method and antibody probe for use therein |
| US4582788A (en) | 1982-01-22 | 1986-04-15 | Cetus Corporation | HLA typing method and cDNA probes used therein |
| ATE53862T1 (de) | 1982-01-22 | 1990-06-15 | Cetus Corp | Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel. |
| US4683194A (en) | 1984-05-29 | 1987-07-28 | Cetus Corporation | Method for detection of polymorphic restriction sites and nucleic acid sequences |
| US4595766A (en) | 1984-10-26 | 1986-06-17 | Ciba-Geigy Corporation | Process for the preparation of an indoline carboxylic acid |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| CA1284931C (en) | 1986-03-13 | 1991-06-18 | Henry A. Erlich | Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids |
| CA1338457C (en) | 1986-08-22 | 1996-07-16 | Henry A. Erlich | Purified thermostable enzyme |
| US6921763B2 (en) | 1999-09-17 | 2005-07-26 | Abbott Laboratories | Pyrazolopyrimidines as therapeutic agents |
| US20040265929A1 (en) * | 2001-11-15 | 2004-12-30 | The Regents Of The University Of Michigan | Humoral response to HIP1 in cancer |
| US20040110802A1 (en) | 2002-08-23 | 2004-06-10 | Atli Thorarensen | Antibacterial benzoic acid derivatives |
| AU2003265382A1 (en) | 2002-08-23 | 2004-03-11 | Pharmacia & Upjohn Company Llc | Antibacterial benzoic acid derivatives |
| KR20080007649A (ko) | 2005-05-11 | 2008-01-22 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 피페리딘환을 가지는 인돌 유도체의 결정 및 그의 제조방법 |
| RU2416603C9 (ru) | 2005-10-25 | 2012-06-20 | Сионоги Энд Ко., Лтд. | Производные аминодигидротиазина |
| US7838542B2 (en) | 2006-06-29 | 2010-11-23 | Kinex Pharmaceuticals, Llc | Bicyclic compositions and methods for modulating a kinase cascade |
| US20100035862A1 (en) | 2008-06-25 | 2010-02-11 | Abbott Laboratories | Novel aza-cyclic indole-2-carboxamides and methods of use thereof |
| EP2330894B8 (en) | 2008-09-03 | 2017-04-19 | BioMarin Pharmaceutical Inc. | Compositions including 6-aminohexanoic acid derivatives as hdac inhibitors |
| US20110021362A1 (en) | 2009-07-20 | 2011-01-27 | Constellation Pharmaceuticals | Agents for stimulating activity of methyl modifying enzymes and methods of use thereof |
| CA2784894A1 (en) | 2009-12-23 | 2011-06-30 | Sanofi | Indolyl-piperidinyl benzylamines as beta-tryptase inhibitors |
| US20130137748A1 (en) | 2010-02-03 | 2013-05-30 | Oncotherapy Science, Inc. | Whsc1 and whsc1l1 for target genes of cancer therapy and diagnosis |
| JP2012107001A (ja) | 2010-10-22 | 2012-06-07 | Shionogi & Co Ltd | インドールアミド化合物を含有する医薬 |
| WO2013063417A1 (en) * | 2011-10-27 | 2013-05-02 | Memorial Sloan-Kettering Cancer Center | Methyltransferase inhibitors for treating cancer |
| EP3119390A4 (en) | 2014-03-21 | 2017-09-20 | Glaxosmithkline Intellectual Property (No. 2) Limited | Methods of treating cancer |
| NZ725860A (en) | 2014-04-04 | 2019-08-30 | Iomet Pharma Ltd | Indole derivatives for use in medicine |
| WO2015164482A1 (en) | 2014-04-22 | 2015-10-29 | The Johns Hopkins University | Inhibitors of drug-resistant mycobacterium tuberculosis |
| US9902702B2 (en) | 2014-07-15 | 2018-02-27 | Bristol-Myers Squibb Company | Spirocycloheptanes as inhibitors of rock |
| WO2016040505A1 (en) | 2014-09-10 | 2016-03-17 | Epizyme, Inc. | Smyd inhibitors |
| WO2016079321A1 (en) * | 2014-11-20 | 2016-05-26 | Cemm Forschungszentrum Für Molekulare Medizin Gmbh | Antagonists of setdb2 for use in the therapy of infectious diseases |
| WO2017106259A1 (en) * | 2015-12-17 | 2017-06-22 | Albert Einstein College Of Medicine, Inc. | Nuclear receptor set domain containing protein 2 transition state and uses thereof |
| CN106317043B (zh) | 2016-08-19 | 2018-11-02 | 成都理工大学 | 一种大麻素受体2激动剂 |
| JP2020530844A (ja) | 2017-08-14 | 2020-10-29 | エピザイム,インコーポレイティド | Setd2を阻害することにより癌を処置する方法 |
| CN112585119A (zh) | 2018-08-14 | 2021-03-30 | Epizyme股份有限公司 | 经取代的吲哚及其使用方法 |
| SG11202105325QA (en) | 2018-11-30 | 2021-06-29 | Epizyme Inc | Methods of treating whsc1-overexpressing cancers by inhibiting setd2 |
| WO2021168313A1 (en) | 2020-02-19 | 2021-08-26 | Epizyme, Inc. | Setd2 inhibitors and related methods and uses, including combination therapies |
| US20240299352A1 (en) | 2021-06-09 | 2024-09-12 | Epizyme, Inc. | Combination therapies with setd2 inhibitors |
| JP2024539726A (ja) | 2021-11-01 | 2024-10-29 | エピザイム,インコーポレイティド | N-((1r,3s)-3-(4-アセチルピペラジン-1-イル)シクロヘキシル)-4-フルオロ-7-メチル-1h-インドール-2-カルボキサミドの結晶形態 |
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2018
- 2018-08-14 JP JP2020508022A patent/JP2020530844A/ja active Pending
- 2018-08-14 IL IL272379A patent/IL272379B2/en unknown
- 2018-08-14 CN CN202411561316.8A patent/CN119405809A/zh active Pending
- 2018-08-14 CA CA3072746A patent/CA3072746A1/en active Pending
- 2018-08-14 MX MX2020001759A patent/MX2020001759A/es unknown
- 2018-08-14 EA EA202090485A patent/EA202090485A1/ru unknown
- 2018-08-14 CN CN201880059329.1A patent/CN111094568A/zh active Pending
- 2018-08-14 KR KR1020207007131A patent/KR20200052294A/ko not_active Ceased
- 2018-08-14 WO PCT/US2018/046698 patent/WO2019036466A1/en not_active Ceased
- 2018-08-14 SG SG11202000839TA patent/SG11202000839TA/en unknown
- 2018-08-14 US US16/639,424 patent/US11952572B2/en active Active
- 2018-08-14 AU AU2018318988A patent/AU2018318988A1/en not_active Abandoned
- 2018-08-14 EP EP18846764.1A patent/EP3669279A4/en active Pending
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2023
- 2023-03-17 JP JP2023042770A patent/JP2023082028A/ja active Pending
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2025
- 2025-02-14 AU AU2025201027A patent/AU2025201027A1/en active Pending
- 2025-03-26 JP JP2025050879A patent/JP2025094223A/ja active Pending
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