JP2020530464A5 - - Google Patents
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- JP2020530464A5 JP2020530464A5 JP2020507088A JP2020507088A JP2020530464A5 JP 2020530464 A5 JP2020530464 A5 JP 2020530464A5 JP 2020507088 A JP2020507088 A JP 2020507088A JP 2020507088 A JP2020507088 A JP 2020507088A JP 2020530464 A5 JP2020530464 A5 JP 2020530464A5
- Authority
- JP
- Japan
- Prior art keywords
- emulsion composition
- composition according
- emulsion
- fish oil
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 73
- 239000000839 emulsion Substances 0.000 claims 66
- 229940057917 medium chain triglycerides Drugs 0.000 claims 20
- 235000021323 fish oil Nutrition 0.000 claims 16
- 235000014113 dietary fatty acids Nutrition 0.000 claims 13
- 239000000194 fatty acid Substances 0.000 claims 13
- 229930195729 fatty acid Natural products 0.000 claims 13
- 150000004665 fatty acids Chemical class 0.000 claims 13
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 12
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 12
- 229940012843 omega-3 fatty acid Drugs 0.000 claims 11
- 239000006014 omega-3 oil Substances 0.000 claims 8
- 239000000654 additive Substances 0.000 claims 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 6
- 229940087168 alpha tocopherol Drugs 0.000 claims 6
- 235000016236 parenteral nutrition Nutrition 0.000 claims 6
- 229960000984 tocofersolan Drugs 0.000 claims 6
- 239000002076 α-tocopherol Substances 0.000 claims 6
- 235000004835 α-tocopherol Nutrition 0.000 claims 6
- 230000000996 additive effect Effects 0.000 claims 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims 4
- 206010061218 Inflammation Diseases 0.000 claims 3
- 206010033645 Pancreatitis Diseases 0.000 claims 3
- 229930003427 Vitamin E Natural products 0.000 claims 3
- CYQFCXCEBYINGO-IAGOWNOFSA-N delta1-THC Chemical compound C1=C(C)CC[C@H]2C(C)(C)OC3=CC(CCCCC)=CC(O)=C3[C@@H]21 CYQFCXCEBYINGO-IAGOWNOFSA-N 0.000 claims 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims 3
- 230000004054 inflammatory process Effects 0.000 claims 3
- 235000016709 nutrition Nutrition 0.000 claims 3
- 238000007911 parenteral administration Methods 0.000 claims 3
- 239000011709 vitamin E Substances 0.000 claims 3
- 235000019165 vitamin E Nutrition 0.000 claims 3
- 229940046009 vitamin E Drugs 0.000 claims 3
- 206010016260 Fatty acid deficiency Diseases 0.000 claims 2
- 206010019708 Hepatic steatosis Diseases 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 208000037112 Intestinal Failure Diseases 0.000 claims 2
- 201000004681 Psoriasis Diseases 0.000 claims 2
- BCKXLBQYZLBQEK-KVVVOXFISA-M Sodium oleate Chemical compound [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O BCKXLBQYZLBQEK-KVVVOXFISA-M 0.000 claims 2
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 claims 2
- 230000007815 allergy Effects 0.000 claims 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims 2
- 206010003246 arthritis Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 235000004626 essential fatty acids Nutrition 0.000 claims 2
- 235000011187 glycerol Nutrition 0.000 claims 2
- 208000006575 hypertriglyceridemia Diseases 0.000 claims 2
- 208000019423 liver disease Diseases 0.000 claims 2
- 235000015097 nutrients Nutrition 0.000 claims 2
- 235000021542 oral nutrition Nutrition 0.000 claims 2
- 150000003904 phospholipids Chemical class 0.000 claims 2
- 238000009097 single-agent therapy Methods 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 2
- 208000003918 Acute Kidney Tubular Necrosis Diseases 0.000 claims 1
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims 1
- 206010002383 Angina Pectoris Diseases 0.000 claims 1
- 206010006803 Burns third degree Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010010317 Congenital absence of bile ducts Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 208000004232 Enteritis Diseases 0.000 claims 1
- 208000022555 Genital disease Diseases 0.000 claims 1
- 235000010469 Glycine max Nutrition 0.000 claims 1
- 244000068988 Glycine max Species 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 208000034486 Multi-organ failure Diseases 0.000 claims 1
- 206010033647 Pancreatitis acute Diseases 0.000 claims 1
- 208000033147 Parenteral nutrition-associated cholestasis Diseases 0.000 claims 1
- 206010063837 Reperfusion injury Diseases 0.000 claims 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 claims 1
- 208000017442 Retinal disease Diseases 0.000 claims 1
- 206010038923 Retinopathy Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 208000030886 Traumatic Brain injury Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 206010000891 acute myocardial infarction Diseases 0.000 claims 1
- 201000003229 acute pancreatitis Diseases 0.000 claims 1
- 230000006978 adaptation Effects 0.000 claims 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 229940114079 arachidonic acid Drugs 0.000 claims 1
- 235000021342 arachidonic acid Nutrition 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 210000000013 bile duct Anatomy 0.000 claims 1
- 201000005271 biliary atresia Diseases 0.000 claims 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 claims 1
- 229940090949 docosahexaenoic acid Drugs 0.000 claims 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims 1
- 206010015037 epilepsy Diseases 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000004968 inflammatory condition Effects 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 208000012947 ischemia reperfusion injury Diseases 0.000 claims 1
- 208000017169 kidney disease Diseases 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 235000006180 nutrition needs Nutrition 0.000 claims 1
- 239000007764 o/w emulsion Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 235000019198 oils Nutrition 0.000 claims 1
- 230000002085 persistent effect Effects 0.000 claims 1
- 230000002028 premature Effects 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 230000009529 traumatic brain injury Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762543437P | 2017-08-10 | 2017-08-10 | |
| US62/543,437 | 2017-08-10 | ||
| PCT/US2018/046206 WO2019032959A1 (en) | 2017-08-10 | 2018-08-10 | METHODS AND COMPOSITIONS RELATING TO EMULSIONS COMPRISING FISH OIL AND / OR OMEGA-3 FATTY ACIDS |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2020530464A JP2020530464A (ja) | 2020-10-22 |
| JP2020530464A5 true JP2020530464A5 (enExample) | 2021-09-16 |
| JPWO2019032959A5 JPWO2019032959A5 (enExample) | 2023-08-02 |
| JP7370317B2 JP7370317B2 (ja) | 2023-10-27 |
Family
ID=65271269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020507088A Active JP7370317B2 (ja) | 2017-08-10 | 2018-08-10 | 魚油および／またはオメガ３脂肪酸を含むエマルジョンに関する方法および組成物 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11324697B2 (enExample) |
| EP (2) | EP3664628B1 (enExample) |
| JP (1) | JP7370317B2 (enExample) |
| KR (2) | KR102677006B1 (enExample) |
| CN (3) | CN118000419A (enExample) |
| AU (1) | AU2018313260B2 (enExample) |
| CA (1) | CA3070481A1 (enExample) |
| DK (1) | DK3664628T3 (enExample) |
| ES (1) | ES3012510T3 (enExample) |
| FI (1) | FI3664628T3 (enExample) |
| HR (1) | HRP20250125T1 (enExample) |
| PH (1) | PH12020500267A1 (enExample) |
| PL (1) | PL3664628T3 (enExample) |
| PT (1) | PT3664628T (enExample) |
| SG (2) | SG11202000592WA (enExample) |
| WO (1) | WO2019032959A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230113738A1 (en) * | 2020-03-06 | 2023-04-13 | Optimega Llc | Fatty acid compositions for enteral use |
| WO2021243526A1 (zh) * | 2020-06-01 | 2021-12-09 | 苏州大学附属儿童医院 | 新生儿肠外营养相关性肝病特异性标志物lncRNA的应用 |
| US20230241124A1 (en) * | 2020-07-14 | 2023-08-03 | Nutrition Lipid Developments | Isotonic lipid emulsion |
| KR20230010404A (ko) | 2021-07-12 | 2023-01-19 | 에이치케이이노엔 주식회사 | 오메가 지방산을 포함하는 약학 조성물 및 이를 포함하는 수액제제 |
| CN116754711B (zh) * | 2023-08-17 | 2023-11-07 | 蓝星安迪苏南京有限公司 | 饲料用乳化剂的乳化能力评估方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2738253A1 (de) | 1977-08-25 | 1979-03-01 | Dabisch Tipp Ex Tech | Koerper mit reversibel temperaturabhaengiger transparenz |
| DE2749265A1 (de) | 1977-11-03 | 1979-05-10 | Linde Ag | Verfahren zur biologischen reinigung von abwasser |
| US4703062A (en) * | 1984-01-16 | 1987-10-27 | Baxter Travenol Laboratories, Inc. | Parenteral nutrition with medium and long chain triglycerides |
| JPS61501558A (ja) * | 1984-01-16 | 1986-07-31 | バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテッド | 中および長鎖トリグリセライドの非経口栄養補給 |
| US4752618A (en) | 1984-07-12 | 1988-06-21 | New England Deaconess Hospital | Method of minimizing efects of infection through diet |
| DE3722540A1 (de) | 1987-07-08 | 1989-01-19 | Fresenius Ag | Fettemulsion, verfahren zu ihrer herstellung und ihre verwendung |
| DE3734147C2 (de) * | 1987-10-09 | 1998-10-29 | Braun Melsungen Ag | Isotone omega-3-fettsäurenhaltige Fettemulsion und ihre Verwendung |
| DE3903056A1 (de) * | 1989-02-02 | 1990-08-09 | Braun Melsungen Ag | Fettemulsion zur intraperitonealen applikation, ihre herstellung und anwendung |
| SE9101642D0 (sv) | 1991-05-30 | 1991-05-30 | Kabi Pharmacia Ab | Phospholipids |
| WO1993009772A1 (fr) | 1991-11-14 | 1993-05-27 | Sagami Chemical Research Center | Medicament contre des maladies hepatiques |
| US5728385A (en) | 1993-08-12 | 1998-03-17 | Classen Immunotherapies, Inc. | Method and composition for an early vaccine to protect against both common infectious diseases and chronic immune mediated disorders or their sequelae |
| US5574065A (en) * | 1994-04-21 | 1996-11-12 | Clintec Nutrition Co. | Method and composition for normalizing injury response |
| JP2000501131A (ja) * | 1995-11-24 | 2000-02-02 | ロダース・クロックラーン・ビー・ブイ | 魚油をベースとする組成物 |
| ATE230262T1 (de) * | 1995-11-28 | 2003-01-15 | Braun Melsungen Ag | Lipidemulsionen mit optimierter hydrolyse sowie deren verwendung |
| US20030068385A1 (en) | 2001-03-23 | 2003-04-10 | Moyer Mary Pat | Accelerated action fatty acid (AAFA) promotes health of normal tissues and minimizes the toxic side effects of chemotherapy |
| CA2452401C (en) * | 2001-07-02 | 2013-02-26 | Suntory Limited | Process for producing fat comprising triglyceride containing highly unsaturated fatty acid |
| EP1279400A1 (en) * | 2001-07-25 | 2003-01-29 | Target Hit sa | Modifying the fatty acid composition of cell membranes of organs and tissues |
| FI114894B (fi) | 2002-05-02 | 2005-01-31 | Omecol Finland Oy | Elintarvikekoostumus |
| DE10254584A1 (de) * | 2002-11-22 | 2004-06-09 | HORST HEIRLER PROJEKTE für Ernährung, Medizin, Ökologie | Verwendung von mittelkettigen Triglyceriden (MCT) zur ernährungsphysiologischen Optimierung des Fettsäurenspektrums in einem diätetischen Lebensmittel für Diabetiker |
| CA2545752C (en) * | 2003-11-12 | 2013-03-26 | Children's Medical Center Corporation | Treatment and prevention of liver disease associated with parenteral nutrition (pn) |
| EP1723096A4 (en) * | 2004-03-04 | 2008-03-05 | Htl High Tech Lipids Ltd | TRIGLYCERIDES STRUCTURES AND EMULSIONS CONTAINING THESE TRIGLYCERIDES |
| CA2573054C (en) * | 2004-07-02 | 2012-10-09 | Baylor Research Institute | Glycogen or polysaccharide storage disease treatment method |
| WO2008036353A2 (en) | 2006-09-19 | 2008-03-27 | The Trustees Of Columbia University In The City Of New York | Omega-3 diglyceride emulsions |
| CN1965806A (zh) * | 2006-11-09 | 2007-05-23 | 华瑞制药有限公司 | 一种含大豆油、中链甘油三酯、橄榄油和鱼油的脂肪乳注射液及其制造方法 |
| US7666828B2 (en) * | 2008-01-22 | 2010-02-23 | Stepan Company | Sulfonated estolides and other derivatives of fatty acids, methods of making them, and compositions and processes employing them |
| US8241672B2 (en) | 2009-03-11 | 2012-08-14 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| US9034389B2 (en) * | 2009-03-11 | 2015-05-19 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
| US20120277316A1 (en) | 2010-01-19 | 2012-11-01 | University of Tennesse Research Foundation a university | Methods and compositions for treating and preventing parenteral nutrition associated liver disease |
| WO2011133841A2 (en) * | 2010-04-23 | 2011-10-27 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Intravenous omega-3 fatty acid compositions & method of use |
| US10052352B2 (en) * | 2011-06-15 | 2018-08-21 | Stable Solutions Llc | Therapeutic application of parenteral krill oil |
| JP5864735B2 (ja) | 2011-06-15 | 2016-02-17 | ステイブル ソリューションズ エルエルシーＳｔａｂｌｅ Ｓｏｌｕｔｉｏｎｓ Ｌｌｃ | 非経口オキアミ油の治療用途 |
| WO2013063067A1 (en) | 2011-10-24 | 2013-05-02 | Stable Solutions Llc | Enriched injectable emulsion containing selected fatty acid triglycerides |
| WO2013127727A1 (en) * | 2012-02-29 | 2013-09-06 | B. Braun Melsungen Ag | Hormone containing emulsion comprising krill phospholipids |
| WO2016040570A2 (en) * | 2014-09-12 | 2016-03-17 | Children's Medical Center Corporation | Dietary emulsion formulations and methods for using the same |
| JP6814148B2 (ja) | 2015-03-31 | 2021-01-13 | フレゼニウス カービ ドイチュラント ゲーエムベーハー | 非経口投与用のエマルション |
-
2018
- 2018-08-10 CN CN202311628291.4A patent/CN118000419A/zh active Pending
- 2018-08-10 WO PCT/US2018/046206 patent/WO2019032959A1/en not_active Ceased
- 2018-08-10 CN CN202311633119.8A patent/CN117918525A/zh active Pending
- 2018-08-10 HR HRP20250125TT patent/HRP20250125T1/hr unknown
- 2018-08-10 EP EP18844969.8A patent/EP3664628B1/en active Active
- 2018-08-10 AU AU2018313260A patent/AU2018313260B2/en active Active
- 2018-08-10 SG SG11202000592WA patent/SG11202000592WA/en unknown
- 2018-08-10 CA CA3070481A patent/CA3070481A1/en active Pending
- 2018-08-10 KR KR1020207003868A patent/KR102677006B1/ko active Active
- 2018-08-10 SG SG10202108769WA patent/SG10202108769WA/en unknown
- 2018-08-10 CN CN201880058296.9A patent/CN111093399A/zh active Pending
- 2018-08-10 PT PT188449698T patent/PT3664628T/pt unknown
- 2018-08-10 EP EP24198450.9A patent/EP4450090A3/en active Pending
- 2018-08-10 PL PL18844969.8T patent/PL3664628T3/pl unknown
- 2018-08-10 KR KR1020247020091A patent/KR20240101693A/ko active Pending
- 2018-08-10 JP JP2020507088A patent/JP7370317B2/ja active Active
- 2018-08-10 ES ES18844969T patent/ES3012510T3/es active Active
- 2018-08-10 FI FIEP18844969.8T patent/FI3664628T3/fi active
- 2018-08-10 US US16/634,194 patent/US11324697B2/en active Active
- 2018-08-10 DK DK18844969.8T patent/DK3664628T3/da active
-
2020
- 2020-02-05 PH PH12020500267A patent/PH12020500267A1/en unknown
-
2022
- 2022-04-07 US US17/715,612 patent/US20220226238A1/en active Pending
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