JP2020530459A5 - - Google Patents
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- Publication number
- JP2020530459A5 JP2020530459A5 JP2020506984A JP2020506984A JP2020530459A5 JP 2020530459 A5 JP2020530459 A5 JP 2020530459A5 JP 2020506984 A JP2020506984 A JP 2020506984A JP 2020506984 A JP2020506984 A JP 2020506984A JP 2020530459 A5 JP2020530459 A5 JP 2020530459A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- retinal
- use according
- retina
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 18
- 210000001525 retina Anatomy 0.000 claims 10
- 208000002780 macular degeneration Diseases 0.000 claims 7
- 208000017442 Retinal disease Diseases 0.000 claims 5
- 238000000034 method Methods 0.000 claims 5
- 201000007737 Retinal degeneration Diseases 0.000 claims 4
- 201000006321 fundus dystrophy Diseases 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 206010012601 diabetes mellitus Diseases 0.000 claims 3
- 230000014509 gene expression Effects 0.000 claims 3
- 238000002347 injection Methods 0.000 claims 3
- 239000007924 injection Substances 0.000 claims 3
- 238000007910 systemic administration Methods 0.000 claims 3
- 208000032578 Inherited retinal disease Diseases 0.000 claims 2
- 208000032430 Retinal dystrophy Diseases 0.000 claims 2
- 206010057430 Retinal injury Diseases 0.000 claims 2
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 2
- 206010064930 age-related macular degeneration Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000017532 inherited retinal dystrophy Diseases 0.000 claims 2
- 208000028867 ischemia Diseases 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 230000004258 retinal degeneration Effects 0.000 claims 2
- NCYCYZXNIZJOKI-IOUUIBBYSA-N 11-cis-retinal Chemical compound O=C/C=C(\C)/C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-IOUUIBBYSA-N 0.000 claims 1
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 1
- 206010025421 Macule Diseases 0.000 claims 1
- 208000035719 Maculopathy Diseases 0.000 claims 1
- 101100393190 Mus musculus Gnat1 gene Proteins 0.000 claims 1
- 206010038933 Retinopathy of prematurity Diseases 0.000 claims 1
- 102000004330 Rhodopsin Human genes 0.000 claims 1
- 108090000820 Rhodopsin Proteins 0.000 claims 1
- 230000002028 premature Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762543782P | 2017-08-10 | 2017-08-10 | |
| US62/543,782 | 2017-08-10 | ||
| PCT/US2018/046272 WO2019032999A1 (en) | 2017-08-10 | 2018-08-10 | PHOTORECEPTOR GENE MODULATOR PHOTOREGULIN 3 FOR THE TREATMENT OF RETINAL DISEASE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020530459A JP2020530459A (ja) | 2020-10-22 |
| JP2020530459A5 true JP2020530459A5 (enExample) | 2021-09-16 |
Family
ID=65272549
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020506984A Pending JP2020530459A (ja) | 2017-08-10 | 2018-08-10 | 網膜の疾患を処置するための光受容体遺伝子のモジュレーターであるフォトレギュリン３ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20200368234A1 (enExample) |
| EP (1) | EP3664801A4 (enExample) |
| JP (1) | JP2020530459A (enExample) |
| CN (1) | CN111093657A (enExample) |
| AU (1) | AU2018313990A1 (enExample) |
| CA (1) | CA3072175A1 (enExample) |
| MX (1) | MX2020001274A (enExample) |
| WO (1) | WO2019032999A1 (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11241460B2 (en) | 2013-03-15 | 2022-02-08 | Astellas Institute For Regenerative Medicine | Photoreceptors and photoreceptor progenitors produced from pluripotent stem cells |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9855314B2 (en) * | 2013-03-01 | 2018-01-02 | The Schepens Eye Research Insititute, Inc. | Methods for modulating development and function of photoreceptor cells |
| WO2016160718A1 (en) * | 2015-03-27 | 2016-10-06 | University Of Washington | Methods for treatment of retinal disease by photoreceptor gene expression modulation |
| CN105343107A (zh) * | 2015-12-03 | 2016-02-24 | 上海中医药大学附属岳阳中西医结合医院 | 雷公藤红素在制备防治视网膜退行性改变相关疾病药物中的应用 |
-
2018
- 2018-08-10 EP EP18844100.0A patent/EP3664801A4/en not_active Withdrawn
- 2018-08-10 MX MX2020001274A patent/MX2020001274A/es unknown
- 2018-08-10 WO PCT/US2018/046272 patent/WO2019032999A1/en not_active Ceased
- 2018-08-10 US US16/637,174 patent/US20200368234A1/en not_active Abandoned
- 2018-08-10 JP JP2020506984A patent/JP2020530459A/ja active Pending
- 2018-08-10 AU AU2018313990A patent/AU2018313990A1/en not_active Abandoned
- 2018-08-10 CA CA3072175A patent/CA3072175A1/en not_active Abandoned
- 2018-08-10 CN CN201880051862.3A patent/CN111093657A/zh active Pending
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