JP2020524993A5 - - Google Patents
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- Publication number
- JP2020524993A5 JP2020524993A5 JP2019568601A JP2019568601A JP2020524993A5 JP 2020524993 A5 JP2020524993 A5 JP 2020524993A5 JP 2019568601 A JP2019568601 A JP 2019568601A JP 2019568601 A JP2019568601 A JP 2019568601A JP 2020524993 A5 JP2020524993 A5 JP 2020524993A5
- Authority
- JP
- Japan
- Prior art keywords
- synthetic
- cron
- existent
- nucleic acid
- orf1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022187239A JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
| JP2024069618A JP2024087003A (ja) | 2017-06-13 | 2024-04-23 | クロンを含む組成物及びその使用 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762518898P | 2017-06-13 | 2017-06-13 | |
| US62/518,898 | 2017-06-13 | ||
| US201762597387P | 2017-12-11 | 2017-12-11 | |
| US62/597,387 | 2017-12-11 | ||
| US201862676730P | 2018-05-25 | 2018-05-25 | |
| US62/676,730 | 2018-05-25 | ||
| PCT/US2018/037379 WO2018232017A1 (en) | 2017-06-13 | 2018-06-13 | Compositions comprising curons and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022187239A Division JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020524993A JP2020524993A (ja) | 2020-08-27 |
| JP2020524993A5 true JP2020524993A5 (https=) | 2021-07-26 |
Family
ID=62846247
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019568601A Withdrawn JP2020524993A (ja) | 2017-06-13 | 2018-06-13 | クロンを含む組成物及びその使用 |
| JP2022187239A Withdrawn JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
| JP2024069618A Pending JP2024087003A (ja) | 2017-06-13 | 2024-04-23 | クロンを含む組成物及びその使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022187239A Withdrawn JP2023010961A (ja) | 2017-06-13 | 2022-11-24 | クロンを含む組成物及びその使用 |
| JP2024069618A Pending JP2024087003A (ja) | 2017-06-13 | 2024-04-23 | クロンを含む組成物及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US20200123203A1 (https=) |
| EP (1) | EP3638797A1 (https=) |
| JP (3) | JP2020524993A (https=) |
| KR (2) | KR20250028508A (https=) |
| CN (1) | CN111108208A (https=) |
| AU (2) | AU2018285860A1 (https=) |
| BR (1) | BR112019026226A2 (https=) |
| CA (1) | CA3066750A1 (https=) |
| IL (1) | IL271275B1 (https=) |
| MX (2) | MX2019015018A (https=) |
| WO (1) | WO2018232017A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| CN114127302A (zh) * | 2018-12-12 | 2022-03-01 | 旗舰先锋创新V股份有限公司 | 用于递送细胞内治疗方式的指环体 |
| CA3119814A1 (en) * | 2018-12-12 | 2020-06-18 | Flagship Pioneering Innovations V, Inc. | Anellosomes for delivering protein replacement therapeutic modalities |
| AU2019396520A1 (en) * | 2018-12-12 | 2021-05-27 | Flagship Pioneering Innovations V, Inc. | Anellosomes for delivering secreted therapeutic modalities |
| MX2021006977A (es) * | 2018-12-12 | 2021-10-13 | Flagship Pioneering Innovations V Inc | Anellosomas y metodos de uso. |
| US11166996B2 (en) | 2018-12-12 | 2021-11-09 | Flagship Pioneering Innovations V, Inc. | Anellovirus compositions and methods of use |
| WO2020252455A1 (en) | 2019-06-13 | 2020-12-17 | The General Hospital Corporation | Engineered human-endogenous virus-like particles and methods of use thereof for delivery to cells |
| JP7759311B2 (ja) | 2019-07-19 | 2025-10-23 | フラッグシップ パイオニアリング イノベーションズ シックス，エルエルシー | リコンビナーゼ組成物及び使用方法 |
| KR20230036109A (ko) * | 2020-06-12 | 2023-03-14 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 바큘로바이러스 발현 시스템 |
| AU2021288320A1 (en) * | 2020-06-12 | 2023-01-19 | Flagship Pioneering Innovations V, Inc. | Tandem anellovirus constructs |
| MX2022016475A (es) * | 2020-06-17 | 2023-04-11 | Flagship Pioneering Innovations V Inc | Metodos de identificacion y caracterizacion de anellovirus y usos de los mismos. |
| CA3189601A1 (en) | 2020-07-24 | 2022-01-27 | The General Hospital Corporation | Enhanced virus-like particles and methods of use thereof for delivery to cells |
| EP4189084A1 (en) * | 2020-07-27 | 2023-06-07 | Wisconsin Alumni Research Foundation | Methods of making unbiased phage libraries |
| TW202235622A (zh) * | 2020-12-23 | 2022-09-16 | 美商旗艦先鋒創新公司 | 包裹rna之指環病毒(anellovirus)蛋白殼之活體外組裝 |
| EP4288115A4 (en) * | 2021-02-08 | 2025-06-18 | Flagship Pioneering Innovations V, Inc. | Hybrid aav-anellovectors |
| WO2023069948A1 (en) * | 2021-10-18 | 2023-04-27 | Flagship Pioneering Innovations Vii, Llc | Dna compositions and related methods |
| TW202430215A (zh) | 2022-12-14 | 2024-08-01 | 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 | 用於將治療劑遞送至骨之組成物和方法 |
| WO2025194138A1 (en) | 2024-03-14 | 2025-09-18 | Tessera Therapeutics, Inc. | St1cas9 compositions and methods for modulating a genome |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR751473A (fr) * | 1932-06-01 | 1933-09-04 | Poste d'incendie | |
| EP0931158A1 (en) | 1996-09-06 | 1999-07-28 | The Trustees Of The University Of Pennsylvania | An inducible method for production of recombinant adeno-associated viruses utilizing t7 polymerase |
| US6693086B1 (en) | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
| US6395472B1 (en) * | 1999-02-05 | 2002-05-28 | Abbott Laboratories | Methods of utilizing the TT virus |
| EP1519714B1 (en) | 2002-06-28 | 2010-10-20 | Protiva Biotherapeutics Inc. | Method and apparatus for producing liposomes |
| CA2532228C (en) | 2003-07-16 | 2017-02-14 | Protiva Biotherapeutics, Inc. | Lipid encapsulated interfering rna |
| EP1664316B1 (en) | 2003-09-15 | 2012-08-29 | Protiva Biotherapeutics Inc. | Polyethyleneglycol-modified lipid compounds and uses thereof |
| CA2559955C (en) | 2004-03-15 | 2016-02-16 | City Of Hope | Methods and compositions for the specific inhibition of gene expression by double-stranded rna |
| JP4764426B2 (ja) | 2004-06-07 | 2011-09-07 | プロチバ バイオセラピューティクス インコーポレイティッド | カチオン性脂質および使用方法 |
| CA2569664C (en) | 2004-06-07 | 2013-07-16 | Protiva Biotherapeutics, Inc. | Lipid encapsulated interfering rna |
| WO2006080951A2 (en) | 2004-07-01 | 2006-08-03 | Yale University | Targeted and high density drug loaded polymeric materials |
| WO2007048046A2 (en) | 2005-10-20 | 2007-04-26 | Protiva Biotherapeutics, Inc. | Sirna silencing of filovirus gene expression |
| CN101346393B (zh) | 2005-11-02 | 2015-07-22 | 普洛体维生物治疗公司 | 修饰的siRNA分子及其应用 |
| US7915399B2 (en) | 2006-06-09 | 2011-03-29 | Protiva Biotherapeutics, Inc. | Modified siRNA molecules and uses thereof |
| CA2721333C (en) | 2008-04-15 | 2020-12-01 | Protiva Biotherapeutics, Inc. | Novel lipid formulations for nucleic acid delivery |
| US20100249214A1 (en) | 2009-02-11 | 2010-09-30 | Dicerna Pharmaceuticals | Multiplex dicer substrate rna interference molecules having joining sequences |
| KR101728655B1 (ko) | 2008-12-18 | 2017-04-19 | 다이서나 파마수이티컬, 인크. | 유전자 발현의 특이적 억제를 위한 연장된 다이서 기질 제제 및 방법 |
| US8603966B2 (en) | 2009-02-27 | 2013-12-10 | The Administrators Of The Tulane Educational Fund | Amino acid-based compounds, their methods of use, and methods of screening |
| WO2011000107A1 (en) | 2009-07-01 | 2011-01-06 | Protiva Biotherapeutics, Inc. | Novel lipid formulations for delivery of therapeutic agents to solid tumors |
| EP2449106B1 (en) | 2009-07-01 | 2015-04-08 | Protiva Biotherapeutics Inc. | Compositions and methods for silencing apolipoprotein b |
| US9676828B2 (en) * | 2010-06-23 | 2017-06-13 | Deutsches Krebsforschungszentrum | Rearranged TT virus molecules for use in diagnosis, prevention and treatment of cancer and autoimmunity |
| NZ713461A (en) * | 2011-04-15 | 2017-02-24 | Compugen Ltd | Polypeptides and polynucleotides, and uses thereof for treatment of immune related disorders and cancer |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| AU2013335451C1 (en) | 2012-10-23 | 2024-07-04 | Toolgen Incorporated | Composition for cleaving a target DNA comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein, and use thereof |
| CN113355357B (zh) | 2012-12-12 | 2024-12-03 | 布罗德研究所有限公司 | 对用于序列操纵的改进的系统、方法和酶组合物进行的工程化和优化 |
| WO2014093655A2 (en) | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Engineering and optimization of systems, methods and compositions for sequence manipulation with functional domains |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| IL239344B2 (en) | 2012-12-12 | 2024-06-01 | Broad Inst Inc | Systems engineering, methods and optimal guiding components for sequence manipulation |
| US20140310830A1 (en) | 2012-12-12 | 2014-10-16 | Feng Zhang | CRISPR-Cas Nickase Systems, Methods And Compositions For Sequence Manipulation in Eukaryotes |
| EP2840140B2 (en) | 2012-12-12 | 2023-02-22 | The Broad Institute, Inc. | Crispr-Cas based method for mutation of prokaryotic cells |
| EP3470089A1 (en) * | 2013-12-12 | 2019-04-17 | The Broad Institute Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
-
2018
- 2018-06-12 IL IL271275A patent/IL271275B1/en unknown
- 2018-06-13 KR KR1020257004957A patent/KR20250028508A/ko active Pending
- 2018-06-13 AU AU2018285860A patent/AU2018285860A1/en not_active Abandoned
- 2018-06-13 CN CN201880051296.6A patent/CN111108208A/zh active Pending
- 2018-06-13 MX MX2019015018A patent/MX2019015018A/es unknown
- 2018-06-13 US US16/622,146 patent/US20200123203A1/en not_active Abandoned
- 2018-06-13 BR BR112019026226-1A patent/BR112019026226A2/pt unknown
- 2018-06-13 CA CA3066750A patent/CA3066750A1/en active Pending
- 2018-06-13 EP EP18738411.0A patent/EP3638797A1/en active Pending
- 2018-06-13 WO PCT/US2018/037379 patent/WO2018232017A1/en not_active Ceased
- 2018-06-13 KR KR1020207000972A patent/KR20200038236A/ko not_active Ceased
- 2018-06-13 JP JP2019568601A patent/JP2020524993A/ja not_active Withdrawn
-
2019
- 2019-03-27 US US16/366,571 patent/US20190211361A1/en not_active Abandoned
- 2019-12-11 MX MX2023011657A patent/MX2023011657A/es unknown
-
2020
- 2020-01-16 US US16/744,363 patent/US20200385757A1/en not_active Abandoned
-
2022
- 2022-07-15 US US17/812,896 patent/US20230279423A1/en not_active Abandoned
- 2022-11-24 JP JP2022187239A patent/JP2023010961A/ja not_active Withdrawn
-
2024
- 2024-04-23 JP JP2024069618A patent/JP2024087003A/ja active Pending
-
2025
- 2025-01-24 AU AU2025200497A patent/AU2025200497A1/en active Pending
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