JP2020522508A5 - - Google Patents
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- JP2020522508A5 JP2020522508A5 JP2019566619A JP2019566619A JP2020522508A5 JP 2020522508 A5 JP2020522508 A5 JP 2020522508A5 JP 2019566619 A JP2019566619 A JP 2019566619A JP 2019566619 A JP2019566619 A JP 2019566619A JP 2020522508 A5 JP2020522508 A5 JP 2020522508A5
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- antibody
- tumor
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023127759A JP2023159179A (ja) | 2017-06-01 | 2023-08-04 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
| JP2025281525A JP2026053613A (ja) | 2017-06-01 | 2025-12-25 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762513831P | 2017-06-01 | 2017-06-01 | |
| US62/513,831 | 2017-06-01 | ||
| PCT/US2018/035670 WO2018223040A1 (en) | 2017-06-01 | 2018-06-01 | Methods of treating a tumor using an anti-pd-1 antibody |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023127759A Division JP2023159179A (ja) | 2017-06-01 | 2023-08-04 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020522508A JP2020522508A (ja) | 2020-07-30 |
| JP2020522508A5 true JP2020522508A5 (https=) | 2021-07-26 |
| JP7780857B2 JP7780857B2 (ja) | 2025-12-05 |
Family
ID=62685228
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019566619A Active JP7780857B2 (ja) | 2017-06-01 | 2018-06-01 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
| JP2023127759A Pending JP2023159179A (ja) | 2017-06-01 | 2023-08-04 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
| JP2025281525A Pending JP2026053613A (ja) | 2017-06-01 | 2025-12-25 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023127759A Pending JP2023159179A (ja) | 2017-06-01 | 2023-08-04 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
| JP2025281525A Pending JP2026053613A (ja) | 2017-06-01 | 2025-12-25 | 抗ｐｄ－１抗体を用いる腫瘍の治療方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US11566073B2 (https=) |
| EP (1) | EP3630840A1 (https=) |
| JP (3) | JP7780857B2 (https=) |
| KR (2) | KR102714702B1 (https=) |
| CN (2) | CN117462668A (https=) |
| WO (1) | WO2018223040A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113967253A (zh) * | 2012-05-15 | 2022-01-25 | 百时美施贵宝公司 | 通过破坏pd-1/pd-l1信号传输的免疫治疗 |
| EP3288982A1 (en) | 2015-04-28 | 2018-03-07 | Bristol-Myers Squibb Company | Treatment of pd-l1-negative melanoma using an anti-pd-1 antibody and an anti-ctla-4 antibody |
| KR102055396B1 (ko) | 2015-08-11 | 2019-12-12 | 우시 바이올로직스 (케이만) 인코포레이티드 | 신규한 항-pd-1 항체 |
| US11566073B2 (en) | 2017-06-01 | 2023-01-31 | Bristol-Myers Squibb Company | Methods of treating a tumor using an anti-PD-1 antibody |
| MA52789A (fr) * | 2018-02-13 | 2021-04-14 | Merck Sharp & Dohme | Méthodes de traitement du cancer avec des anticorps anti-pd-1 |
| CN111821434A (zh) * | 2019-04-17 | 2020-10-27 | 上海君实生物医药科技股份有限公司 | 抗pd-1抗体在制备治疗实体瘤的药物中的用途 |
| AU2019403339A1 (en) * | 2018-12-19 | 2021-07-08 | Strata Oncology, Inc. | Methods of detecting and treating subjects with checkpoint inhibitor-responsive cancer |
| CN114269376A (zh) * | 2019-05-03 | 2022-04-01 | 豪夫迈·罗氏有限公司 | 用抗pd-l1抗体治疗癌症的方法 |
| US12275986B2 (en) * | 2020-01-06 | 2025-04-15 | Duke University | Biomarkers associated with checkpoint immune therapy and methods of using same |
| CN110923329B (zh) * | 2020-02-06 | 2020-05-12 | 至本医疗科技（上海）有限公司 | Fgfr4点突变在预测非小细胞肺癌患者对免疫检查点抑制剂疗法敏感性中的应用 |
| CN111440822A (zh) * | 2020-04-16 | 2020-07-24 | 苏州大学附属第二医院 | 一种突变lats1质粒的构建与应用 |
| WO2022087402A1 (en) | 2020-10-23 | 2022-04-28 | Bristol-Myers Squibb Company | Lag-3 antagonist therapy for lung cancer |
| CN112961920A (zh) * | 2021-03-24 | 2021-06-15 | 臻和(北京)生物科技有限公司 | 一种预测肝胆肿瘤患者免疫检查点抑制剂联合靶向治疗疗效的方法及产品 |
| JP7806990B2 (ja) * | 2021-08-10 | 2026-01-27 | 国立大学法人 新潟大学 | 内胚葉嚢胞の悪性化に関連する遺伝子の検出方法 |
| CN113943806A (zh) * | 2021-11-04 | 2022-01-18 | 至本医疗科技（上海）有限公司 | 预测肺腺癌患者对免疫疗法敏感性的生物标志物、应用和装置 |
| WO2023209035A1 (en) * | 2022-04-26 | 2023-11-02 | F. Hoffmann-La Roche Ag | Methods and systems for predicting cancer therapy response |
| CN114931637B (zh) * | 2022-06-27 | 2025-02-18 | 中山大学中山眼科中心 | Pdl1抗体在角膜新生血管疾病中的应用 |
| CN116449009A (zh) * | 2023-01-30 | 2023-07-18 | 上海秤信生物科技有限公司 | 预测肺癌三期患者的免疫新辅助疗效的自身抗体标志物 |
| WO2025085707A1 (en) * | 2023-10-19 | 2025-04-24 | Tesaro, Inc. | Methods of treating cancer with anti-pd-1 agents |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1210428B1 (en) | 1999-08-23 | 2015-03-18 | Dana-Farber Cancer Institute, Inc. | Pd-1, a receptor for b7-4, and uses therefor |
| CN1753912B (zh) | 2002-12-23 | 2011-11-02 | 惠氏公司 | 抗pd-1抗体及其用途 |
| RU2494107C2 (ru) | 2005-05-09 | 2013-09-27 | Оно Фармасьютикал Ко., Лтд. | Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами |
| CN104356236B (zh) | 2005-07-01 | 2020-07-03 | E.R.施贵宝&圣斯有限责任公司 | 抗程序性死亡配体1(pd-l1)的人单克隆抗体 |
| HRP20131167T1 (hr) | 2007-06-18 | 2014-01-03 | Merck Sharp & Dohme B.V. | Antitijela za humani receptor programirane smrti pd-1 |
| WO2009114335A2 (en) | 2008-03-12 | 2009-09-17 | Merck & Co., Inc. | Pd-1 binding proteins |
| AU2009333580B2 (en) | 2008-12-09 | 2016-07-07 | Genentech, Inc. | Anti-PD-L1 antibodies and their use to enhance T-cell function |
| NZ628923A (en) | 2009-11-24 | 2016-02-26 | Medimmune Ltd | Targeted binding agents against b7-h1 |
| KR101970025B1 (ko) | 2011-04-20 | 2019-04-17 | 메디뮨 엘엘씨 | Ｂ7-ｈ1 및 ｐｄ-1과 결합하는 항체 및 다른 분자들 |
| HRP20201595T1 (hr) | 2011-11-28 | 2020-12-11 | Merck Patent Gmbh | Anti-pd-l1 protutijela i njihova uporaba |
| CN113967253A (zh) | 2012-05-15 | 2022-01-25 | 百时美施贵宝公司 | 通过破坏pd-1/pd-l1信号传输的免疫治疗 |
| HK1204557A1 (en) | 2012-05-31 | 2015-11-27 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind pd-l1 |
| JP6742903B2 (ja) | 2013-05-02 | 2020-08-19 | アナプティスバイオ インコーポレイティッド | プログラム死−１（ｐｄ−１）に対する抗体 |
| US9676853B2 (en) | 2013-05-31 | 2017-06-13 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind PD-1 |
| CN104250302B (zh) | 2013-06-26 | 2017-11-14 | 上海君实生物医药科技股份有限公司 | 抗pd‑1抗体及其应用 |
| EA034666B1 (ru) | 2013-09-13 | 2020-03-04 | Бейджин Свитзерланд Гмбх | Антитело против pd-1 и его применение для лечения рака или вирусной инфекции и фрагмент антитела |
| MY184154A (en) | 2013-12-12 | 2021-03-23 | Shanghai hengrui pharmaceutical co ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| DE112014005975T5 (de) * | 2013-12-17 | 2016-09-15 | Kymab Limited | Menschliche Ziele |
| TWI681969B (zh) | 2014-01-23 | 2020-01-11 | 美商再生元醫藥公司 | 針對ｐｄ-１的人類抗體 |
| SG10201900002QA (en) | 2014-01-24 | 2019-02-27 | Dana Farber Cancer Institue Inc | Antibody molecules to pd-1 and uses thereof |
| WO2015116868A2 (en) * | 2014-01-29 | 2015-08-06 | Caris Mpi, Inc. | Molecular profiling of immune modulators |
| CA2944903A1 (en) * | 2014-04-24 | 2015-10-29 | Dana-Farber Cancer Institute, Inc. | Tumor suppressor and oncogene biomarkers predictive of anti-immune checkpoint inhibitor response |
| EP3916017A1 (en) | 2014-12-22 | 2021-12-01 | PD-1 Acquisition Group, LLC | Anti-pd-1 antibodies |
| CN108112254B (zh) | 2015-03-13 | 2022-01-28 | 西托姆克斯治疗公司 | 抗-pdl1抗体、可活化的抗-pdl1抗体、及其使用方法 |
| WO2016191751A1 (en) * | 2015-05-28 | 2016-12-01 | Bristol-Myers Squibb Company | Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody |
| WO2016197367A1 (en) | 2015-06-11 | 2016-12-15 | Wuxi Biologics (Shanghai) Co. Ltd. | Novel anti-pd-l1 antibodies |
| WO2017019846A1 (en) | 2015-07-30 | 2017-02-02 | Macrogenics, Inc. | Pd-1-binding molecules and methods use thereof |
| WO2017020291A1 (en) | 2015-08-06 | 2017-02-09 | Wuxi Biologics (Shanghai) Co. Ltd. | Novel anti-pd-l1 antibodies |
| WO2017024465A1 (en) | 2015-08-10 | 2017-02-16 | Innovent Biologics (Suzhou) Co., Ltd. | Pd-1 antibodies |
| WO2017024515A1 (en) | 2015-08-11 | 2017-02-16 | Wuxi Biologics (Cayman) Inc. | Novel anti-pd-1 antibodies |
| KR102055396B1 (ko) | 2015-08-11 | 2019-12-12 | 우시 바이올로직스 (케이만) 인코포레이티드 | 신규한 항-pd-1 항체 |
| AR105654A1 (es) | 2015-08-24 | 2017-10-25 | Lilly Co Eli | Anticuerpos pd-l1 (ligando 1 de muerte celular programada) |
| CN114605548A (zh) | 2015-09-01 | 2022-06-10 | 艾吉纳斯公司 | 抗-pd-1抗体及其使用方法 |
| WO2017040990A1 (en) * | 2015-09-03 | 2017-03-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| US10954301B2 (en) | 2015-12-14 | 2021-03-23 | Macrogenics, Inc. | Bispecific molecules having immunoreactivity with PD-1 and CTLA-4, and methods of use thereof |
| MX2018007295A (es) | 2016-01-11 | 2019-03-28 | Armo Biosciences Inc | Interleucina 10 en la produccion de linfocitos t cd8+especificos para el antigeno y metodos de uso de estos. |
| WO2017132827A1 (en) | 2016-02-02 | 2017-08-10 | Innovent Biologics (Suzhou) Co., Ltd. | Pd-1 antibodies |
| CN111491361B (zh) | 2016-02-02 | 2023-10-24 | 华为技术有限公司 | 确定发射功率的方法、用户设备和基站 |
| WO2017210624A1 (en) | 2016-06-03 | 2017-12-07 | Bristol-Myers Squibb Company | Anti-pd-1 antibody for use in a method of treating a tumor |
| US11566073B2 (en) | 2017-06-01 | 2023-01-31 | Bristol-Myers Squibb Company | Methods of treating a tumor using an anti-PD-1 antibody |
| CN113249483B (zh) * | 2021-06-10 | 2021-10-08 | 北京泛生子基因科技有限公司 | 一种检测肿瘤突变负荷的基因组合、系统及应用 |
-
2018
- 2018-06-01 US US16/617,725 patent/US11566073B2/en active Active
- 2018-06-01 WO PCT/US2018/035670 patent/WO2018223040A1/en not_active Ceased
- 2018-06-01 EP EP18733121.0A patent/EP3630840A1/en active Pending
- 2018-06-01 KR KR1020197038639A patent/KR102714702B1/ko active Active
- 2018-06-01 JP JP2019566619A patent/JP7780857B2/ja active Active
- 2018-06-01 KR KR1020247032911A patent/KR20240149982A/ko active Pending
- 2018-06-01 CN CN202311104154.0A patent/CN117462668A/zh active Pending
- 2018-06-01 CN CN201880035434.1A patent/CN110678483B/zh active Active
-
2023
- 2023-01-30 US US18/161,713 patent/US12227576B2/en active Active
- 2023-08-04 JP JP2023127759A patent/JP2023159179A/ja active Pending
-
2025
- 2025-01-09 US US19/015,341 patent/US20250145713A1/en active Pending
- 2025-12-25 JP JP2025281525A patent/JP2026053613A/ja active Pending
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