JP2020519293A5 - - Google Patents
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- Publication number
- JP2020519293A5 JP2020519293A5 JP2019562424A JP2019562424A JP2020519293A5 JP 2020519293 A5 JP2020519293 A5 JP 2020519293A5 JP 2019562424 A JP2019562424 A JP 2019562424A JP 2019562424 A JP2019562424 A JP 2019562424A JP 2020519293 A5 JP2020519293 A5 JP 2020519293A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence identity
- mtcr
- cell receptor
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762505406P | 2017-05-12 | 2017-05-12 | |
| US62/505,406 | 2017-05-12 | ||
| US201762609614P | 2017-12-22 | 2017-12-22 | |
| US62/609,614 | 2017-12-22 | ||
| US201862625051P | 2018-02-01 | 2018-02-01 | |
| US62/625,051 | 2018-02-01 | ||
| PCT/US2018/030637 WO2018208553A1 (en) | 2017-05-12 | 2018-05-02 | Human alpha fetoprotein-specific t cell receptors and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020519293A JP2020519293A (ja) | 2020-07-02 |
| JP2020519293A5 true JP2020519293A5 (enExample) | 2021-06-10 |
| JP7169298B2 JP7169298B2 (ja) | 2022-11-10 |
Family
ID=64095949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019562424A Expired - Fee Related JP7169298B2 (ja) | 2017-05-12 | 2018-05-02 | ヒトアルファフェトタンパク質特異的ｔ細胞受容体およびその使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11041011B2 (enExample) |
| EP (1) | EP3622074A4 (enExample) |
| JP (1) | JP7169298B2 (enExample) |
| KR (1) | KR20200006985A (enExample) |
| CN (1) | CN110662760A (enExample) |
| AU (1) | AU2018266562A1 (enExample) |
| SG (1) | SG11201909751TA (enExample) |
| WO (1) | WO2018208553A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3622074A4 (en) | 2017-05-12 | 2021-01-13 | Augusta University Research Institute, Inc. | HUMAN ALPHA FETOPROTEIN SPECIFIC T CELL RECEPTORS AND THEIR USES |
| CN110776562B (zh) * | 2018-07-30 | 2022-06-17 | 香雪生命科学技术（广东）有限公司 | 一种识别afp抗原的t细胞受体 |
| CN113072636B (zh) * | 2020-01-06 | 2024-05-28 | 香雪生命科学技术（广东）有限公司 | 一种识别afp的t细胞受体及其编码序列 |
| CN113321725B (zh) * | 2020-02-28 | 2024-06-11 | 香雪生命科学技术（广东）有限公司 | 一种识别afp的t细胞受体 |
| CN113684258B (zh) * | 2020-05-18 | 2024-08-20 | 上海赛比曼生物科技有限公司 | 用于检测鼠源tcr转基因拷贝数的试剂盒及方法 |
| CN115181177A (zh) * | 2021-04-02 | 2022-10-14 | 香雪生命科学技术（广东）有限公司 | 针对afp的t细胞受体 |
| EP4347644A4 (en) * | 2021-05-31 | 2026-01-14 | Nanjing Legend Biotech Co Ltd | ANTIBODIES TARGETTING AFP/MHC PEPTIDE COMPLEXES AND THEIR USES |
| CN114121142B (zh) * | 2021-09-02 | 2023-10-31 | 四川大学华西医院 | 一种新型基因修饰增强型ny-eso-1特异型tcr-t模型构建方法及应用 |
| CN114853880B (zh) * | 2022-04-24 | 2023-11-10 | 中国科学院微生物研究所 | Wt1抗原特异性t细胞受体及其抗肿瘤用途 |
| US20260226184A1 (en) * | 2023-01-26 | 2026-08-06 | Dana-Farber Cancer Institute, Inc. | Developing a car-engager platform to enhance the functionality and/or persistence of car t cells |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2975607B2 (ja) | 1989-03-16 | 1999-11-10 | 三洋電機株式会社 | Ａｆｃ回路 |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| DE69334275D1 (de) | 1992-08-21 | 2009-05-20 | Univ Bruxelles | Immunoglobuline ohne Leichtkette |
| US6005079A (en) | 1992-08-21 | 1999-12-21 | Vrije Universiteit Brussels | Immunoglobulins devoid of light chains |
| WO1994025591A1 (en) | 1993-04-29 | 1994-11-10 | Unilever N.V. | PRODUCTION OF ANTIBODIES OR (FUNCTIONALIZED) FRAGMENTS THEREOF DERIVED FROM HEAVY CHAIN IMMUNOGLOBULINS OF $i(CAMELIDAE) |
| GB9325182D0 (en) | 1993-12-08 | 1994-02-09 | T Cell Sciences Inc | Humanized antibodies or binding proteins thereof specific for t cell subpopulations exhibiting select beta chain variable regions |
| US20090304657A1 (en) | 2006-05-03 | 2009-12-10 | The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services | Chimeric t cell receptors and related materials and methods of use |
| EP1878744A1 (en) | 2006-07-13 | 2008-01-16 | Max-Delbrück-Centrum für Molekulare Medizin (MDC) | Epitope-tag for surface-expressed T-cell receptor proteins, uses thereof and method of selecting host cells expressing them |
| US8105831B2 (en) * | 2007-03-09 | 2012-01-31 | University Of Washington | Parvoviral production of HLA homozygous cells |
| EP2504358B1 (en) | 2009-11-24 | 2016-10-19 | ChronTech Pharma AB | T cell receptors specific for immunodominant ctl epitopes of hcv |
| ES2635335T3 (es) * | 2010-09-20 | 2017-10-03 | Biontech Cell & Gene Therapies Gmbh | Receptores de células T específicos de antígeno y epítopos de células T |
| GB201313377D0 (en) | 2013-07-26 | 2013-09-11 | Adaptimmune Ltd | T cell receptors |
| EP3043641B1 (en) * | 2013-09-12 | 2019-09-11 | Icahn School of Medicine at Mount Sinai | Methods of making transgenic animals with t cell receptors that are specific to a flourescent protein |
| CN104087592B (zh) * | 2014-05-13 | 2016-01-27 | 天津医科大学总医院 | Afp158-166特异性tcr基因及其转基因t细胞及体外增殖方法及用途 |
| SG10201913978RA (en) * | 2014-11-26 | 2020-03-30 | The United States Of America As Represented By The Secretary | Anti-mutated kras t cell receptors |
| CN105802909B (zh) * | 2014-12-31 | 2021-01-01 | 中国医学科学院基础医学研究所 | 具有her2特异性tcr的t细胞制备物及其用途 |
| EP3622074A4 (en) | 2017-05-12 | 2021-01-13 | Augusta University Research Institute, Inc. | HUMAN ALPHA FETOPROTEIN SPECIFIC T CELL RECEPTORS AND THEIR USES |
-
2018
- 2018-05-02 EP EP18799369.6A patent/EP3622074A4/en not_active Withdrawn
- 2018-05-02 WO PCT/US2018/030637 patent/WO2018208553A1/en not_active Ceased
- 2018-05-02 AU AU2018266562A patent/AU2018266562A1/en not_active Abandoned
- 2018-05-02 JP JP2019562424A patent/JP7169298B2/ja not_active Expired - Fee Related
- 2018-05-02 US US15/969,211 patent/US11041011B2/en active Active
- 2018-05-02 SG SG11201909751T patent/SG11201909751TA/en unknown
- 2018-05-02 KR KR1020197035091A patent/KR20200006985A/ko not_active Ceased
- 2018-05-02 CN CN201880030341.XA patent/CN110662760A/zh active Pending
-
2021
- 2021-06-21 US US17/353,409 patent/US12173045B2/en active Active
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