JP2020517665A5 - - Google Patents
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- Publication number
- JP2020517665A5 JP2020517665A5 JP2019557488A JP2019557488A JP2020517665A5 JP 2020517665 A5 JP2020517665 A5 JP 2020517665A5 JP 2019557488 A JP2019557488 A JP 2019557488A JP 2019557488 A JP2019557488 A JP 2019557488A JP 2020517665 A5 JP2020517665 A5 JP 2020517665A5
- Authority
- JP
- Japan
- Prior art keywords
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- refitrimod
- sclc
- tlr
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010041067 Small cell lung cancer Diseases 0.000 claims 3
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 3
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 102100024222 B-lymphocyte antigen CD19 Human genes 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 claims 1
- 235000019796 monopotassium phosphate Nutrition 0.000 claims 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 claims 1
- 239000011574 phosphorus Substances 0.000 claims 1
- 229910052698 phosphorus Inorganic materials 0.000 claims 1
- 239000001103 potassium chloride Substances 0.000 claims 1
- 235000011164 potassium chloride Nutrition 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17000678.7 | 2017-04-22 | ||
| EP17000678.7A EP3392345A1 (en) | 2017-04-22 | 2017-04-22 | Biomarker for small cell lung cancer therapy |
| PCT/EP2018/060377 WO2018193137A1 (en) | 2017-04-22 | 2018-04-23 | Biomarker for small cell lung cancer therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020517665A JP2020517665A (ja) | 2020-06-18 |
| JP2020517665A5 true JP2020517665A5 (enExample) | 2021-05-27 |
Family
ID=58668698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019557488A Pending JP2020517665A (ja) | 2017-04-22 | 2018-04-23 | 小細胞肺がん治療のためのバイオマーカー |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200385732A1 (enExample) |
| EP (2) | EP3392345A1 (enExample) |
| JP (1) | JP2020517665A (enExample) |
| CN (1) | CN110914428A (enExample) |
| TW (1) | TW201843451A (enExample) |
| WO (1) | WO2018193137A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU92821B1 (en) | 2015-09-09 | 2017-03-20 | Mologen Ag | Combination comprising immunostimulatory oligonucleotides |
| GB2542425A (en) | 2015-09-21 | 2017-03-22 | Mologen Ag | Means for the treatment of HIV |
| WO2018039629A2 (en) | 2016-08-25 | 2018-03-01 | Northwestern University | Micellar spherical nucleic acids from thermoresponsive, traceless templates |
| WO2018209270A1 (en) | 2017-05-11 | 2018-11-15 | Northwestern University | Adoptive cell therapy using spherical nucleic acids (snas) |
| EP4104830A1 (en) * | 2021-06-16 | 2022-12-21 | Burghardt Wittig | Sequential innate and adaptive immune modulation for cancer treatment |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19935756A1 (de) | 1999-07-27 | 2001-02-08 | Mologen Forschungs Entwicklung | Kovalent geschlossenes Nukleinsäuremolekül zur Immunstimulation |
| WO2004041183A2 (en) * | 2002-11-01 | 2004-05-21 | The Regents Of The University Of California | Methods of treating pulmonary fibrotic disorders |
| WO2006015560A1 (de) | 2004-08-09 | 2006-02-16 | Mologen Ag | Immunmodulierendes mittel in verbindung mit chemotherapeutischen massnahmen |
| CN103260415A (zh) * | 2010-03-05 | 2013-08-21 | 铂雅制药公司 | 治疗小细胞肺癌的方法 |
| GB201021867D0 (en) | 2010-12-23 | 2011-02-02 | Mologen Ag | Non-coding immunomodulatory DNA construct |
| GB2514591A (en) | 2013-05-30 | 2014-12-03 | Mologen Ag | Predictive biomarker for cancer therapy |
| WO2016040167A1 (en) * | 2014-09-08 | 2016-03-17 | Brandon Higgs | Compositions and methods for detecting and treating small cell lung cancer |
| LU92821B1 (en) | 2015-09-09 | 2017-03-20 | Mologen Ag | Combination comprising immunostimulatory oligonucleotides |
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2017
- 2017-04-22 EP EP17000678.7A patent/EP3392345A1/en not_active Ceased
-
2018
- 2018-04-20 TW TW107113560A patent/TW201843451A/zh unknown
- 2018-04-23 JP JP2019557488A patent/JP2020517665A/ja active Pending
- 2018-04-23 US US16/606,969 patent/US20200385732A1/en not_active Abandoned
- 2018-04-23 EP EP18721720.3A patent/EP3612639A1/en not_active Withdrawn
- 2018-04-23 CN CN201880033928.6A patent/CN110914428A/zh active Pending
- 2018-04-23 WO PCT/EP2018/060377 patent/WO2018193137A1/en not_active Ceased