JP2015521598A5 - - Google Patents
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- Publication number
- JP2015521598A5 JP2015521598A5 JP2015517321A JP2015517321A JP2015521598A5 JP 2015521598 A5 JP2015521598 A5 JP 2015521598A5 JP 2015517321 A JP2015517321 A JP 2015517321A JP 2015517321 A JP2015517321 A JP 2015517321A JP 2015521598 A5 JP2015521598 A5 JP 2015521598A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- compound according
- pharmaceutically acceptable
- acceptable salt
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 12
- 150000003839 salts Chemical class 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940124597 therapeutic agent Drugs 0.000 claims 2
- 206010003119 arrhythmia Diseases 0.000 claims 1
- 230000006793 arrhythmia Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261657913P | 2012-06-11 | 2012-06-11 | |
| US61/657,913 | 2012-06-11 | ||
| PCT/US2013/044882 WO2013188254A1 (en) | 2012-06-11 | 2013-06-10 | Phosphoramidic acid prodrugs of 5 - [5 - phenyl- 4 - (pyridin- 2 - ylmethylamino) quinazolin- 2 - yl] pyridine- 3 - sulfonamide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015521598A JP2015521598A (ja) | 2015-07-30 |
| JP2015521598A5 true JP2015521598A5 (enExample) | 2016-06-30 |
| JP6234450B2 JP6234450B2 (ja) | 2017-11-22 |
Family
ID=48670111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015517321A Active JP6234450B2 (ja) | 2012-06-11 | 2013-06-10 | ５−［５−フェニル−４−（ピリジン−２−イルメチルアミノ）キナゾリン−２−イル］ピリジン−３−スルホンアミドのホスホロアミド酸プロドラッグ |
Country Status (34)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105008366B (zh) * | 2013-03-11 | 2017-11-14 | 百时美施贵宝公司 | 作为钾离子通道抑制剂的吡咯并哒嗪类化合物 |
| US9050345B2 (en) * | 2013-03-11 | 2015-06-09 | Bristol-Myers Squibb Company | Pyrrolotriazines as potassium ion channel inhibitors |
| JP6395798B2 (ja) * | 2013-03-11 | 2018-09-26 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | カリウムイオンチャネル阻害剤としてのピロロトリアジン |
| ES2969792T3 (es) * | 2015-11-19 | 2024-05-22 | Biohaven Therapeutics Ltd | Profármacos de amina de compuestos farmacéuticos |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5612359A (en) | 1994-08-26 | 1997-03-18 | Bristol-Myers Squibb Company | Substituted biphenyl isoxazole sulfonamides |
| GB9514380D0 (en) * | 1995-07-13 | 1995-09-13 | Knoll Ag | Therapeutic agents |
| TW536540B (en) | 1997-01-30 | 2003-06-11 | Bristol Myers Squibb Co | Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe |
| KR20010083092A (ko) | 1998-07-06 | 2001-08-31 | 스티븐 비. 데이비스 | 이중 안지오텐신 엔도텔린 수용체 길항제로서의 비페닐술폰아미드 |
| ES2215474B1 (es) | 2002-12-24 | 2005-12-16 | J. URIACH & CIA S.A. | Nuevos derivados de fosforamida. |
| AR049847A1 (es) | 2004-07-29 | 2006-09-06 | Merck & Co Inc | Inhibidores de los canales de potasio |
| WO2006066879A2 (en) * | 2004-12-21 | 2006-06-29 | Devgen N.V. | Compounds with kv4 ion channel activity |
| EP3575288B1 (en) | 2009-09-03 | 2021-10-27 | Bristol-Myers Squibb Company | Quinazolines as potassium ion channel inhibitors |
| WO2011029054A1 (en) | 2009-09-04 | 2011-03-10 | The Regents Of The University Of Michigan | Compositions and methods for treatment of leukemia |
| AR079814A1 (es) | 2009-12-31 | 2012-02-22 | Otsuka Pharma Co Ltd | Compuestos heterociclicos, composiciones farmaceuticas que los contienen y sus usos |
| JP5848761B2 (ja) * | 2010-06-24 | 2016-01-27 | アルカーメス ファーマ アイルランド リミテッド | Ｎｈ酸性化合物のプロドラッグ：エステル、カルボネート、カルバメートおよびホスホネートの誘導体 |
| JP2016516691A (ja) * | 2013-03-11 | 2016-06-09 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | カリウムイオンチャネル阻害剤としてのイソキノリン |
| US9242966B2 (en) * | 2013-03-11 | 2016-01-26 | Bristol-Myers Squibb Company | Phthalazines as potassium ion channel inhibitors |
| US9050345B2 (en) * | 2013-03-11 | 2015-06-09 | Bristol-Myers Squibb Company | Pyrrolotriazines as potassium ion channel inhibitors |
-
2013
- 2013-06-10 ES ES13730444.0T patent/ES2675314T3/es active Active
- 2013-06-10 BR BR112014030629-0A patent/BR112014030629B1/pt active IP Right Grant
- 2013-06-10 HU HUE13730444A patent/HUE039210T2/hu unknown
- 2013-06-10 JP JP2015517321A patent/JP6234450B2/ja active Active
- 2013-06-10 EP EP13730444.0A patent/EP2858987B1/en active Active
- 2013-06-10 MY MYPI2014703715A patent/MY169219A/en unknown
- 2013-06-10 DK DK13730444.0T patent/DK2858987T3/en active
- 2013-06-10 AR ARP130102043 patent/AR091402A1/es not_active Application Discontinuation
- 2013-06-10 HR HRP20180815TT patent/HRP20180815T8/hr unknown
- 2013-06-10 SM SM20180369T patent/SMT201800369T1/it unknown
- 2013-06-10 WO PCT/US2013/044882 patent/WO2013188254A1/en not_active Ceased
- 2013-06-10 EA EA201492256A patent/EA024692B1/ru not_active IP Right Cessation
- 2013-06-10 CN CN201380030478.2A patent/CN104350048B/zh active Active
- 2013-06-10 MX MX2014014525A patent/MX356699B/es active IP Right Grant
- 2013-06-10 NZ NZ703632A patent/NZ703632A/en unknown
- 2013-06-10 KR KR1020157000330A patent/KR102092984B1/ko active Active
- 2013-06-10 LT LTEP13730444.0T patent/LT2858987T/lt unknown
- 2013-06-10 PE PE2014002405A patent/PE20150228A1/es active IP Right Grant
- 2013-06-10 SG SG11201408076WA patent/SG11201408076WA/en unknown
- 2013-06-10 RS RS20180738A patent/RS57376B1/sr unknown
- 2013-06-10 CA CA2876359A patent/CA2876359C/en active Active
- 2013-06-10 SI SI201331033T patent/SI2858987T1/en unknown
- 2013-06-10 TW TW102120593A patent/TWI571470B/zh active
- 2013-06-10 US US14/406,543 patent/US9238666B2/en active Active
- 2013-06-10 PT PT137304440T patent/PT2858987T/pt unknown
- 2013-06-10 PL PL13730444T patent/PL2858987T3/pl unknown
- 2013-06-10 AU AU2013274619A patent/AU2013274619B2/en active Active
-
2014
- 2014-11-28 TN TN2014000499A patent/TN2014000499A1/fr unknown
- 2014-12-04 IL IL236074A patent/IL236074A/en active IP Right Grant
- 2014-12-09 PH PH12014502747A patent/PH12014502747B1/en unknown
- 2014-12-10 CL CL2014003361A patent/CL2014003361A1/es unknown
-
2015
- 2015-01-08 CO CO15003999A patent/CO7160032A2/es unknown
- 2015-01-09 ZA ZA2015/00161A patent/ZA201500161B/en unknown
-
2018
- 2018-07-13 CY CY20181100733T patent/CY1120432T1/el unknown
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