JP2020516293A5 - - Google Patents
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- JP2020516293A5 JP2020516293A5 JP2019555915A JP2019555915A JP2020516293A5 JP 2020516293 A5 JP2020516293 A5 JP 2020516293A5 JP 2019555915 A JP2019555915 A JP 2019555915A JP 2019555915 A JP2019555915 A JP 2019555915A JP 2020516293 A5 JP2020516293 A5 JP 2020516293A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- optionally
- deletion
- nucleotides
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762484841P | 2017-04-12 | 2017-04-12 | |
| US62/484,841 | 2017-04-12 | ||
| PCT/US2018/027375 WO2018191545A1 (en) | 2017-04-12 | 2018-04-12 | Multiple transgene recombinant adenovirus |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020516293A JP2020516293A (ja) | 2020-06-11 |
| JP2020516293A5 true JP2020516293A5 (https=) | 2021-05-27 |
| JP7301748B2 JP7301748B2 (ja) | 2023-07-03 |
Family
ID=63792941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019555915A Active JP7301748B2 (ja) | 2017-04-12 | 2018-04-12 | 複数トランスジーン組み換えアデノウイルス |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12036247B2 (https=) |
| EP (1) | EP3610025A4 (https=) |
| JP (1) | JP7301748B2 (https=) |
| KR (1) | KR20200006058A (https=) |
| CN (1) | CN110914440A (https=) |
| EA (1) | EA201990822A1 (https=) |
| WO (1) | WO2018191545A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201507393TA (en) | 2013-03-14 | 2015-10-29 | Salk Inst For Biological Studi | Oncolytic adenovirus compositions |
| KR102608590B1 (ko) | 2014-09-24 | 2023-12-01 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| WO2017147269A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| EP3532082A4 (en) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES |
| CN112292449A (zh) | 2018-04-09 | 2021-01-29 | 萨克生物研究学院 | 具有增强的复制特性的溶瘤腺病毒组合物 |
| WO2022007800A1 (zh) * | 2020-07-06 | 2022-01-13 | 嘉兴安宇生物科技有限公司 | 一种非洲猪瘟的重组腺病毒疫苗及其构建方法 |
| CN116621965A (zh) * | 2022-05-06 | 2023-08-22 | 珠海丽凡达生物技术有限公司 | 治疗性核酸分子、混合物、药物及在治疗实体瘤中的应用 |
| WO2024015876A1 (en) | 2022-07-13 | 2024-01-18 | Epicentrx, Inc. | Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5670488A (en) * | 1992-12-03 | 1997-09-23 | Genzyme Corporation | Adenovirus vector for gene therapy |
| AUPN477695A0 (en) | 1995-08-14 | 1995-09-07 | Commonwealth Scientific And Industrial Research Organisation | Gene therapy |
| GB9626029D0 (en) | 1996-12-14 | 1997-01-29 | Univ Leeds | EVH-1 vectors |
| US20040234505A1 (en) | 1998-09-23 | 2004-11-25 | Stuart Naylor | Polynucleotide constructs and uses thereof |
| CN1183250C (zh) | 2000-12-01 | 2005-01-05 | 卫健生物科技有限公司 | 高效表达肿瘤血管生成抑制因子的肿瘤细胞内特异性增殖的病毒及其构建方法 |
| AU2002256388A1 (en) | 2001-04-30 | 2002-11-11 | Cell Genesys, Inc. | Viral-mediated delivery and in vivo expression of polynucleotides encoding anti-angiogenic proteins |
| WO2005017149A1 (en) | 2003-06-03 | 2005-02-24 | Cell Genesys, Inc. | Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site |
| US20050136035A1 (en) | 2003-06-03 | 2005-06-23 | Derek Ko | Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site |
| US7473418B2 (en) | 2004-03-25 | 2009-01-06 | Cell Genesys, Inc. | Pan cancer oncolytic vectors and methods of use thereof |
| SG158133A1 (en) | 2004-12-31 | 2010-01-29 | Sonne Holm | Method for reversing multiple resistance in animal cells |
| KR100911624B1 (ko) | 2007-05-14 | 2009-08-12 | 연세대학교 산학협력단 | Ｉｌ－１２ 및 ｉｌ－２３의 효율적인 공동발현 방법 |
| KR100896483B1 (ko) | 2007-07-13 | 2009-05-08 | 연세대학교 산학협력단 | Ｉｌ-12 및 4-1ｂｂｌ을 발현하는 종양 선택적 살상 재조합아데노바이러스 및 수지상 세포를 유효성분으로 포함하는항종양용 약제학적 조성물 |
| HUE026386T2 (en) | 2009-03-02 | 2016-06-28 | Univ California | Tumor-selective adenovirus e1a and e1b mutants |
| KR20130010121A (ko) | 2010-03-23 | 2013-01-25 | 인트렉손 코포레이션 | 치료적 단백질을 조건부로 발현하는 벡터，상기 벡터를 포함하는 숙주 세포 및 이의 용도 |
| KR101253276B1 (ko) | 2010-07-27 | 2013-04-10 | 윤채옥 | 복합 유전자 치료용 항종양 조성물 |
| US20130243731A1 (en) | 2010-09-24 | 2013-09-19 | Oncos Therapeutics Oy | Oncolytic adenoviral vectors coding for monoclonal anti-ctla-4 antibodies |
| WO2013116778A2 (en) | 2012-02-02 | 2013-08-08 | Board Of Regents | Immunogenic adenovirus |
| DK2986311T3 (en) | 2013-04-18 | 2019-02-25 | Tilt Biotherapeutics Oy | IMPROVED ADOPTIVE CELL THERAPY |
| CN103614416B (zh) | 2013-09-30 | 2016-09-07 | 中国人民解放军第二军医大学东方肝胆外科医院 | 一种携带人穿膜肽p53与GM-CSF基因的重组溶瘤腺病毒及其用途 |
| JP6566214B2 (ja) | 2014-05-28 | 2019-08-28 | 国立大学法人 岡山大学 | Ｒｅｉｃ遺伝子を発現する制限増殖型アデノウイルス |
| KR102608590B1 (ko) | 2014-09-24 | 2023-12-01 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| WO2018083259A1 (en) * | 2016-11-03 | 2018-05-11 | Psioxus Therapeutics Limited | Oncolytic adenovirus encoding transgenes |
| US10232053B2 (en) | 2016-12-30 | 2019-03-19 | Trieza Therapeutics, Inc. | Immunomodulatory oncolytic adenoviral vectors, and methods of production and use thereof for treatment of cancer |
| CA3052090A1 (en) | 2017-01-30 | 2018-08-02 | Epicentrx, Inc. | Multiple transgene recombinant adenovirus |
| US20200155625A1 (en) | 2017-05-24 | 2020-05-21 | Epicentrx, Inc. | Anti-angiogenic adenovirus |
-
2017
- 2017-09-27 EA EA201990822A patent/EA201990822A1/ru unknown
-
2018
- 2018-04-12 CN CN201880038592.2A patent/CN110914440A/zh active Pending
- 2018-04-12 US US16/604,675 patent/US12036247B2/en active Active
- 2018-04-12 WO PCT/US2018/027375 patent/WO2018191545A1/en not_active Ceased
- 2018-04-12 KR KR1020197033395A patent/KR20200006058A/ko active Pending
- 2018-04-12 EP EP18784495.6A patent/EP3610025A4/en not_active Withdrawn
- 2018-04-12 JP JP2019555915A patent/JP7301748B2/ja active Active
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