JP2020521470A5 - - Google Patents

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JP2020521470A5
JP2020521470A5 JP2019565334A JP2019565334A JP2020521470A5 JP 2020521470 A5 JP2020521470 A5 JP 2020521470A5 JP 2019565334 A JP2019565334 A JP 2019565334A JP 2019565334 A JP2019565334 A JP 2019565334A JP 2020521470 A5 JP2020521470 A5 JP 2020521470A5
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JP
Japan
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cancer
seq
deletion
recombinant adenovirus
optionally
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JP2019565334A
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English (en)
Japanese (ja)
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JP7245175B2 (ja
JP2020521470A (ja
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Priority claimed from PCT/US2018/034487 external-priority patent/WO2018218083A1/en
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Publication of JP2020521470A5 publication Critical patent/JP2020521470A5/ja
Priority to JP2023037694A priority Critical patent/JP2023063392A/ja
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Publication of JP7245175B2 publication Critical patent/JP7245175B2/ja
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JP2019565334A 2017-05-24 2018-05-24 抗脈管形成アデノウイルス Active JP7245175B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023037694A JP2023063392A (ja) 2017-05-24 2023-03-10 抗脈管形成アデノウイルス

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762510647P 2017-05-24 2017-05-24
US62/510,647 2017-05-24
US201762514351P 2017-06-02 2017-06-02
US62/514,351 2017-06-02
PCT/US2018/034487 WO2018218083A1 (en) 2017-05-24 2018-05-24 Anti-angiogenic adenovirus

Related Child Applications (1)

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JP2023037694A Division JP2023063392A (ja) 2017-05-24 2023-03-10 抗脈管形成アデノウイルス

Publications (3)

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JP2020521470A JP2020521470A (ja) 2020-07-27
JP2020521470A5 true JP2020521470A5 (https=) 2021-07-26
JP7245175B2 JP7245175B2 (ja) 2023-03-23

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JP2019565334A Active JP7245175B2 (ja) 2017-05-24 2018-05-24 抗脈管形成アデノウイルス
JP2023037694A Pending JP2023063392A (ja) 2017-05-24 2023-03-10 抗脈管形成アデノウイルス

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JP2023037694A Pending JP2023063392A (ja) 2017-05-24 2023-03-10 抗脈管形成アデノウイルス

Country Status (9)

Country Link
US (1) US20200155625A1 (https=)
EP (1) EP3630959A4 (https=)
JP (2) JP7245175B2 (https=)
KR (1) KR20200020723A (https=)
CN (1) CN111448309A (https=)
AU (1) AU2018271999A1 (https=)
CA (1) CA3064892A1 (https=)
MX (1) MX2019014059A (https=)
WO (1) WO2018218083A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
KR102608590B1 (ko) 2014-09-24 2023-12-01 솔크 인스티튜트 포 바이올로지칼 스터디즈 종양 살상 바이러스 및 이의 사용방법
WO2017147269A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3532082A4 (en) 2016-12-12 2020-08-26 Salk Institute for Biological Studies SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES
EA201990822A1 (ru) 2017-04-12 2020-01-09 Эписентарикс, Инк. Иммуномодулирующие слитые белки
CN112292449A (zh) 2018-04-09 2021-01-29 萨克生物研究学院 具有增强的复制特性的溶瘤腺病毒组合物
CN110295195A (zh) * 2019-06-26 2019-10-01 浙江理工大学 靶向肝癌的溶瘤腺病毒gd55-gsdme的构建和应用
WO2021248101A1 (en) * 2020-06-05 2021-12-09 Epicentrx, Inc. Mono- and multi-valent sars-cov-2 adenoviral vector vaccines and sars-cov-2 immune globulin and methods of use
CN115120744B (zh) * 2021-03-24 2025-01-28 四川大学 重组人内皮抑素腺病毒与抗pd-1抗体或抗pd-l1抗体在制备抗肿瘤药物中的用途
CN114931634B (zh) * 2022-03-18 2023-03-17 广州达博生物制品有限公司 E10a与pd1单抗对肿瘤的联合治疗方法和制药用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1183250C (zh) * 2000-12-01 2005-01-05 卫健生物科技有限公司 高效表达肿瘤血管生成抑制因子的肿瘤细胞内特异性增殖的病毒及其构建方法
AU2002256388A1 (en) * 2001-04-30 2002-11-11 Cell Genesys, Inc. Viral-mediated delivery and in vivo expression of polynucleotides encoding anti-angiogenic proteins
US20050136035A1 (en) * 2003-06-03 2005-06-23 Derek Ko Cell specific replication-competent viral vectors comprising a self processing peptide cleavage site
SG158133A1 (en) * 2004-12-31 2010-01-29 Sonne Holm Method for reversing multiple resistance in animal cells
KR100896483B1 (ko) * 2007-07-13 2009-05-08 연세대학교 산학협력단 Il-12 및 4-1bbl을 발현하는 종양 선택적 살상 재조합아데노바이러스 및 수지상 세포를 유효성분으로 포함하는항종양용 약제학적 조성물
HUE026386T2 (en) * 2009-03-02 2016-06-28 Univ California Tumor-selective adenovirus e1a and e1b mutants
CA3052090A1 (en) * 2017-01-30 2018-08-02 Epicentrx, Inc. Multiple transgene recombinant adenovirus

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