JP2020516258A5 - - Google Patents
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- JP2020516258A5 JP2020516258A5 JP2019555112A JP2019555112A JP2020516258A5 JP 2020516258 A5 JP2020516258 A5 JP 2020516258A5 JP 2019555112 A JP2019555112 A JP 2019555112A JP 2019555112 A JP2019555112 A JP 2019555112A JP 2020516258 A5 JP2020516258 A5 JP 2020516258A5
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- JP
- Japan
- Prior art keywords
- compound
- target
- cells
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- combination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023052030A JP7795493B2 (ja) | 2017-04-10 | 2023-03-28 | ゲノム編集効率を増大させるための化合物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17165784.4A EP3388517A1 (en) | 2017-04-10 | 2017-04-10 | Compounds for increasing genome editing efficiency |
| EP17165784.4 | 2017-04-10 | ||
| EP17203591.7 | 2017-11-24 | ||
| EP17203591.7A EP3489357A1 (en) | 2017-11-24 | 2017-11-24 | Compounds for increasing genome editing efficiency |
| PCT/EP2018/059173 WO2018189186A1 (en) | 2017-04-10 | 2018-04-10 | Compounds for increasing genome editing efficiency |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023052030A Division JP7795493B2 (ja) | 2017-04-10 | 2023-03-28 | ゲノム編集効率を増大させるための化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020516258A JP2020516258A (ja) | 2020-06-11 |
| JP2020516258A5 true JP2020516258A5 (https=) | 2021-05-20 |
| JP7319194B2 JP7319194B2 (ja) | 2023-08-01 |
Family
ID=62116381
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019555112A Active JP7319194B2 (ja) | 2017-04-10 | 2018-04-10 | ゲノム編集効率を増大させるための化合物 |
| JP2023052030A Active JP7795493B2 (ja) | 2017-04-10 | 2023-03-28 | ゲノム編集効率を増大させるための化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023052030A Active JP7795493B2 (ja) | 2017-04-10 | 2023-03-28 | ゲノム編集効率を増大させるための化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12173309B2 (https=) |
| EP (1) | EP3610008A1 (https=) |
| JP (2) | JP7319194B2 (https=) |
| KR (2) | KR102537447B1 (https=) |
| CN (1) | CN110691848B (https=) |
| CA (1) | CA3058697A1 (https=) |
| IL (1) | IL269887B2 (https=) |
| SG (1) | SG11201909432SA (https=) |
| WO (1) | WO2018189186A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200299729A1 (en) * | 2017-09-08 | 2020-09-24 | Life Technologies Corporation | Methods for improved homologous recombination and compositions thereof |
| JP7235153B2 (ja) * | 2017-12-29 | 2023-03-08 | 株式会社三洋物産 | 遊技機 |
| JP7483612B2 (ja) | 2018-01-17 | 2024-05-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | ゲノム編集効率を増加するためのキノキサリノン化合物、組成物、方法、およびキット |
| CA3088788A1 (en) * | 2018-01-17 | 2019-07-25 | Vertex Pharmaceuticals Incorporated | Dna-pk inhibitors |
| JP7235154B2 (ja) * | 2018-02-15 | 2023-03-08 | 株式会社三洋物産 | 遊技機 |
| JP7231076B2 (ja) * | 2018-03-08 | 2023-03-01 | 株式会社三洋物産 | 遊技機 |
| WO2020127738A1 (en) | 2018-12-21 | 2020-06-25 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Dna-pkcs inhibitors for increasing genome editing efficiency |
| JP2020103418A (ja) * | 2018-12-26 | 2020-07-09 | 株式会社三洋物産 | 遊技機 |
| JP2020130466A (ja) * | 2019-02-15 | 2020-08-31 | 株式会社三洋物産 | 遊技機 |
| JP7234740B2 (ja) * | 2019-03-28 | 2023-03-08 | 株式会社三洋物産 | 遊技機 |
| JP7234741B2 (ja) * | 2019-03-28 | 2023-03-08 | 株式会社三洋物産 | 遊技機 |
| JP7234761B2 (ja) * | 2019-04-11 | 2023-03-08 | 株式会社三洋物産 | 遊技機 |
| JP7234760B2 (ja) * | 2019-04-11 | 2023-03-08 | 株式会社三洋物産 | 遊技機 |
| JP2021186294A (ja) * | 2020-05-29 | 2021-12-13 | 株式会社三洋物産 | 遊技機 |
| CN112359065B (zh) * | 2020-09-21 | 2023-04-07 | 中国医学科学院血液病医院(中国医学科学院血液学研究所) | 一种提高基因敲入效率的小分子组合物 |
| KR102545913B1 (ko) * | 2021-02-02 | 2023-06-22 | 재단법인 아산사회복지재단 | 히스톤 탈아세틸화 억제제를 포함하는 염기교정 기술의 효율성 및 정확도 향상용 조성물 및 이의 용도 |
| EP4347815A2 (en) * | 2021-05-24 | 2024-04-10 | New York Genome Center, Inc. | Compositions and methods for increasing efficiency of precise editing repair |
| CN113403309B (zh) * | 2021-05-24 | 2022-08-16 | 珠海舒桐医疗科技有限公司 | 非同源双链寡聚核苷酸片段在基因敲除系统中的应用 |
| EP4095246A1 (en) | 2021-05-27 | 2022-11-30 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Novel crispr grnas |
| US20230070047A1 (en) * | 2021-07-06 | 2023-03-09 | Regents Of The University Of Minnesota | Method to enhance gene editing |
| JP2023105111A (ja) * | 2021-10-27 | 2023-07-28 | 株式会社三洋物産 | 遊技機 |
| JP2023105108A (ja) * | 2021-10-27 | 2023-07-28 | 株式会社三洋物産 | 遊技機 |
| JP2023105110A (ja) * | 2021-10-27 | 2023-07-28 | 株式会社三洋物産 | 遊技機 |
| JP2023063369A (ja) * | 2022-01-07 | 2023-05-09 | 株式会社三洋物産 | 遊技機 |
| JP2023053387A (ja) * | 2022-02-04 | 2023-04-12 | 株式会社三洋物産 | 遊技機 |
| JP2023060269A (ja) * | 2022-04-01 | 2023-04-27 | 株式会社三洋物産 | 遊技機 |
| JP2023060270A (ja) * | 2022-04-01 | 2023-04-27 | 株式会社三洋物産 | 遊技機 |
| CN114717207B (zh) * | 2022-04-25 | 2023-03-07 | 苏州泓迅生物科技股份有限公司 | 一种酵母细胞同源重组酶系、dna体外组装试剂及其应用 |
| WO2025212548A1 (en) | 2024-04-02 | 2025-10-09 | Sigma-Aldrich Co. Llc | Methods and compositions for improvement of base editor and homology directed repair genome editing outcomes |
| WO2026005012A1 (ja) * | 2024-06-28 | 2026-01-02 | 学校法人自治医科大学 | インビトロ及びインビボのゲノム編集における相同組換えの効率を高める方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013188881A1 (en) | 2012-06-15 | 2013-12-19 | President And Fellows Of Harvard College | Compounds, compositions and methods for treating or preventing neurodegenerative disorders |
| US10227610B2 (en) * | 2013-02-25 | 2019-03-12 | Sangamo Therapeutics, Inc. | Methods and compositions for enhancing nuclease-mediated gene disruption |
| MX2015017312A (es) * | 2013-06-17 | 2017-04-10 | Broad Inst Inc | Suministro y uso de composiciones, vectores y sistemas crispr-cas para la modificación dirigida y terapia hepáticas. |
| ES2730378T3 (es) * | 2014-08-27 | 2019-11-11 | Caribou Biosciences Inc | Procedimientos para incrementar la eficiencia de la modificación mediada por Cas9 |
| CA2963820A1 (en) * | 2014-11-07 | 2016-05-12 | Editas Medicine, Inc. | Methods for improving crispr/cas-mediated genome-editing |
-
2018
- 2018-04-10 SG SG11201909432S patent/SG11201909432SA/en unknown
- 2018-04-10 CN CN201880035645.5A patent/CN110691848B/zh active Active
- 2018-04-10 US US16/603,377 patent/US12173309B2/en active Active
- 2018-04-10 EP EP18722407.6A patent/EP3610008A1/en active Pending
- 2018-04-10 CA CA3058697A patent/CA3058697A1/en active Pending
- 2018-04-10 JP JP2019555112A patent/JP7319194B2/ja active Active
- 2018-04-10 IL IL269887A patent/IL269887B2/en unknown
- 2018-04-10 KR KR1020197032518A patent/KR102537447B1/ko active Active
- 2018-04-10 KR KR1020237017487A patent/KR102778328B1/ko active Active
- 2018-04-10 WO PCT/EP2018/059173 patent/WO2018189186A1/en not_active Ceased
-
2023
- 2023-03-28 JP JP2023052030A patent/JP7795493B2/ja active Active
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| JP2020516258A5 (https=) | ||
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