JP2020513794A5 - - Google Patents

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JP2020513794A5
JP2020513794A5 JP2019546831A JP2019546831A JP2020513794A5 JP 2020513794 A5 JP2020513794 A5 JP 2020513794A5 JP 2019546831 A JP2019546831 A JP 2019546831A JP 2019546831 A JP2019546831 A JP 2019546831A JP 2020513794 A5 JP2020513794 A5 JP 2020513794A5
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JP2020513794A (ja
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Priority claimed from PCT/US2018/019763 external-priority patent/WO2018160496A1/en
Publication of JP2020513794A publication Critical patent/JP2020513794A/ja
Publication of JP2020513794A5 publication Critical patent/JP2020513794A5/ja
Priority to JP2023020284A priority Critical patent/JP7668551B2/ja
Priority to JP2023144942A priority patent/JP2023182587A/ja
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JP2019546831A 2017-02-28 2018-02-26 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用 Withdrawn JP2020513794A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023020284A JP7668551B2 (ja) 2017-02-28 2023-02-13 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用
JP2023144942A JP2023182587A (ja) 2017-02-28 2023-09-07 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762464925P 2017-02-28 2017-02-28
US62/464,925 2017-02-28
PCT/US2018/019763 WO2018160496A1 (en) 2017-02-28 2018-02-26 Differentiation and use of human microglia-like cells from pluripotent stem cells and hematopoietic progenitors

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JP2023020284A Division JP7668551B2 (ja) 2017-02-28 2023-02-13 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用

Publications (2)

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JP2020513794A JP2020513794A (ja) 2020-05-21
JP2020513794A5 true JP2020513794A5 (https=) 2021-04-08

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JP2019546831A Withdrawn JP2020513794A (ja) 2017-02-28 2018-02-26 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用
JP2023020284A Active JP7668551B2 (ja) 2017-02-28 2023-02-13 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用
JP2023144942A Pending JP2023182587A (ja) 2017-02-28 2023-09-07 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用

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JP2023020284A Active JP7668551B2 (ja) 2017-02-28 2023-02-13 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用
JP2023144942A Pending JP2023182587A (ja) 2017-02-28 2023-09-07 多能性幹細胞および造血始原細胞からのヒトミクログリア様細胞の分化と使用

Country Status (5)

Country Link
US (2) US20200239844A1 (https=)
EP (2) EP4272551A3 (https=)
JP (3) JP2020513794A (https=)
CA (1) CA3054730A1 (https=)
WO (1) WO2018160496A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201619876D0 (en) 2016-11-24 2017-01-11 Cambridge Entpr Ltd Controllable transcription
JOP20190248A1 (ar) 2017-04-21 2019-10-20 Amgen Inc بروتينات ربط مولد ضد trem2 واستخداماته
CA3114651A1 (en) * 2018-09-28 2020-04-02 Memorial Sloan-Kettering Cancer Center Stem cell-derived human microglial cells, methods of making and methods of use
US12577531B2 (en) 2019-03-29 2026-03-17 Agency For Science, Technology And Research Microglia-sufficient brain organoids
WO2020243657A1 (en) * 2019-05-30 2020-12-03 President And Fellows Of Harvard College Reproducible brain organoids and methods of making
GB2584664B (en) * 2019-06-10 2023-05-24 Newcells Biotech Ltd Improved retinal organoids and methods of making the same
CN110205295B (zh) * 2019-06-25 2021-10-29 中国科学院动物研究所 一种多能干细胞诱导产生小胶质细胞的方法及试剂盒
KR20210077634A (ko) * 2019-12-17 2021-06-25 코아스템(주) 인간 만능 줄기세포로부터 3d 오가노이드를 이용하여 미세교세포를 다량 확보하는 미세교세포의 분화방법
CN112011509A (zh) * 2020-09-25 2020-12-01 南京中医药大学 脊髓损伤大鼠原代小胶质细胞分离方法及应用
CN114426951B (zh) * 2020-10-29 2024-05-14 北京赛尔湃腾科技咨询合伙企业(有限合伙) 利用多能干细胞制备小胶质细胞样细胞的方法
DE202022002866U1 (de) 2021-04-01 2024-03-20 The Regents Of The University Of California Genetische Modifikation von Säugetierzellen zur Verleihung von Resistenz gegen CSF1R-Antagonisten
US20260108560A1 (en) * 2022-07-13 2026-04-23 The Regents Of The University Of California Transplanting stem cell-derived microglia to treat leukodystrophies
US20240269189A1 (en) 2022-12-19 2024-08-15 FUJIFILM Holdings America Corporation Extracellular vesicle-enriched secretome composition derived from induced pluripotent stem cell derived-microglia and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2759978C (en) * 2009-04-28 2020-06-02 Life & Brain Gmbh Method for obtaining human microglial precursor cells from pluripotent stem cells
CA2972598C (en) * 2014-12-31 2024-03-12 Wisconsin Alumni Research Foundation Human pluripotent stem cell-based models for predictive developmental neural toxicity
US10081792B2 (en) * 2014-12-31 2018-09-25 Wisconsin Alumni Research Foundation Derivation of human microglia from pluripotent stem cells
AU2016211671B2 (en) * 2015-01-26 2022-05-26 Fate Therapeutics, Inc. Methods and compositions for inducing hematopoietic cell differentiation
US11136548B2 (en) * 2015-06-24 2021-10-05 Whitehead Institute For Biomedical Research Culture medium for generating microglia from pluripotent stem cells and related methods
EP3423564A4 (en) * 2016-03-03 2019-08-21 New York Stem Cell Foundation, Inc. MICROGLIA DERIVED FROM PLURIPOTENTIAL STEM CELLS AND METHOD FOR THE PRODUCTION AND USE THEREOF

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