JP2020510436A5 - - Google Patents
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- Publication number
- JP2020510436A5 JP2020510436A5 JP2019548614A JP2019548614A JP2020510436A5 JP 2020510436 A5 JP2020510436 A5 JP 2020510436A5 JP 2019548614 A JP2019548614 A JP 2019548614A JP 2019548614 A JP2019548614 A JP 2019548614A JP 2020510436 A5 JP2020510436 A5 JP 2020510436A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleic acid
- malodor
- receptor
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 claims description 22
- 108020004707 nucleic acids Proteins 0.000 claims description 16
- 102000039446 nucleic acids Human genes 0.000 claims description 16
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 12
- 230000000295 complement effect Effects 0.000 claims description 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims description 6
- 239000013604 expression vector Substances 0.000 claims description 5
- YWHLKYXPLRWGSE-UHFFFAOYSA-N Dimethyl trisulfide Chemical group CSSSC YWHLKYXPLRWGSE-UHFFFAOYSA-N 0.000 claims 22
- WQOXQRCZOLPYPM-UHFFFAOYSA-N dimethyl disulfide Chemical compound CSSC WQOXQRCZOLPYPM-UHFFFAOYSA-N 0.000 claims 20
- 239000000126 substance Substances 0.000 claims 20
- 229920001184 polypeptide Polymers 0.000 claims 13
- 102000004196 processed proteins & peptides Human genes 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 13
- 102000012547 Olfactory receptors Human genes 0.000 claims 12
- 108050002069 Olfactory receptors Proteins 0.000 claims 12
- 210000004027 cell Anatomy 0.000 claims 12
- 150000001875 compounds Chemical class 0.000 claims 10
- 102000005962 receptors Human genes 0.000 claims 10
- 108020003175 receptors Proteins 0.000 claims 10
- 238000000034 method Methods 0.000 claims 8
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 230000000694 effects Effects 0.000 claims 5
- 101000990753 Homo sapiens Olfactory receptor 52N5 Proteins 0.000 claims 4
- 102100030578 Olfactory receptor 52N5 Human genes 0.000 claims 4
- 101001121144 Homo sapiens Olfactory receptor 2L13 Proteins 0.000 claims 3
- 102100026579 Olfactory receptor 2L13 Human genes 0.000 claims 3
- 101000594462 Homo sapiens Olfactory receptor 2AJ1 Proteins 0.000 claims 2
- -1 OR2OR Proteins 0.000 claims 2
- 102100035516 Olfactory receptor 2AJ1 Human genes 0.000 claims 2
- 101000614009 Homo sapiens Olfactory receptor 4S2 Proteins 0.000 claims 1
- 101000992264 Homo sapiens Olfactory receptor 5T1 Proteins 0.000 claims 1
- 102100040567 Olfactory receptor 4S2 Human genes 0.000 claims 1
- 102100031852 Olfactory receptor 5T1 Human genes 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 210000003527 eukaryotic cell Anatomy 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 235000019645 odor Nutrition 0.000 claims 1
- 210000001236 prokaryotic cell Anatomy 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023010950A JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
| JP2025061793A JP2025106387A (ja) | 2017-03-09 | 2025-04-03 | 悪臭調節化合物の同定方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762469256P | 2017-03-09 | 2017-03-09 | |
| US62/469,256 | 2017-03-09 | ||
| PCT/EP2018/055753 WO2018162638A1 (en) | 2017-03-09 | 2018-03-08 | Method of identifying malodor modulating compounds |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023010950A Division JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020510436A JP2020510436A (ja) | 2020-04-09 |
| JP2020510436A5 true JP2020510436A5 (https=) | 2021-03-25 |
| JP7606816B2 JP7606816B2 (ja) | 2024-12-26 |
Family
ID=61911520
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548614A Active JP7606816B2 (ja) | 2017-03-09 | 2018-03-08 | 悪臭調節化合物の同定方法 |
| JP2023010950A Active JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
| JP2025061793A Pending JP2025106387A (ja) | 2017-03-09 | 2025-04-03 | 悪臭調節化合物の同定方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023010950A Active JP7662685B2 (ja) | 2017-03-09 | 2023-01-27 | 悪臭調節化合物の同定方法 |
| JP2025061793A Pending JP2025106387A (ja) | 2017-03-09 | 2025-04-03 | 悪臭調節化合物の同定方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11787847B2 (https=) |
| EP (1) | EP3592766A1 (https=) |
| JP (3) | JP7606816B2 (https=) |
| CN (2) | CN117330756A (https=) |
| BR (1) | BR112019018196A2 (https=) |
| SG (1) | SG11201907884XA (https=) |
| WO (1) | WO2018162638A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018162638A1 (en) * | 2017-03-09 | 2018-09-13 | Firmenich Sa | Method of identifying malodor modulating compounds |
| BR112022003088A2 (pt) * | 2019-10-04 | 2022-06-21 | Firmenich & Cie | Método para atribuir tonalidades olfativas à ativação de receptores olfativos e métodos para identificar compostos que têm as tonalidades atribuídas |
| JP7658911B2 (ja) * | 2019-11-01 | 2025-04-08 | 高砂香料工業株式会社 | 悪臭抑制素材のスクリーニング方法 |
| US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
| US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
| US12251991B2 (en) | 2020-08-20 | 2025-03-18 | Denso International America, Inc. | Humidity control for olfaction sensors |
| US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
| US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
| US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
| US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
| US12269315B2 (en) | 2020-08-20 | 2025-04-08 | Denso International America, Inc. | Systems and methods for measuring and managing odor brought into rental vehicles |
| US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
| US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
| US12377711B2 (en) | 2020-08-20 | 2025-08-05 | Denso International America, Inc. | Vehicle feature control systems and methods based on smoking |
| WO2022270481A1 (ja) | 2021-06-22 | 2022-12-29 | 花王株式会社 | 嗅覚受容体の発現方法及び応答測定方法 |
| JP2023084475A (ja) * | 2021-12-07 | 2023-06-19 | 花王株式会社 | カルボン酸を原因とするにおいの抑制剤の評価及び／又は選択方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002331062A1 (en) * | 2001-08-09 | 2003-11-17 | The Trustees Of Columbia University In The City Of New York | Mouse olfactory receptor gene superfamily specification |
| BR112015032700B1 (pt) | 2013-06-29 | 2022-12-20 | Firmenich Sa | Métodos de identificação, isolamento e uso de receptores de aroma e odorizante |
| WO2015020158A1 (ja) | 2013-08-09 | 2015-02-12 | 国立大学法人東京大学 | ムスク系香料のスクリーニング方法 |
| AU2016274783B2 (en) | 2015-06-10 | 2021-08-05 | Firmenich Sa | Method of identifying musk compounds |
| EP3308168B1 (en) | 2015-06-10 | 2020-04-01 | Firmenich SA | Cell lines for screening odorant and aroma receptors |
| JP6371336B2 (ja) * | 2015-06-17 | 2018-08-08 | 花王株式会社 | ポリスルフィド化合物の臭いの抑制剤 |
| WO2016204211A1 (ja) | 2015-06-17 | 2016-12-22 | 花王株式会社 | スルフィド化合物の臭いの抑制剤の評価又は選択方法 |
| JP6920786B2 (ja) | 2015-08-26 | 2021-08-18 | ドイチェス クレブスフォルシュンクスツェントルム | 免疫ウイルス療法のためのｒｎａウイルス |
| WO2018162638A1 (en) | 2017-03-09 | 2018-09-13 | Firmenich Sa | Method of identifying malodor modulating compounds |
-
2018
- 2018-03-08 WO PCT/EP2018/055753 patent/WO2018162638A1/en not_active Ceased
- 2018-03-08 US US16/492,115 patent/US11787847B2/en active Active
- 2018-03-08 SG SG11201907884XA patent/SG11201907884XA/en unknown
- 2018-03-08 EP EP18716115.3A patent/EP3592766A1/en active Pending
- 2018-03-08 BR BR112019018196-2A patent/BR112019018196A2/pt not_active Application Discontinuation
- 2018-03-08 CN CN202311093055.7A patent/CN117330756A/zh active Pending
- 2018-03-08 CN CN201880016397.XA patent/CN110418801B/zh active Active
- 2018-03-08 JP JP2019548614A patent/JP7606816B2/ja active Active
-
2023
- 2023-01-27 JP JP2023010950A patent/JP7662685B2/ja active Active
- 2023-10-13 US US18/486,417 patent/US20240117001A1/en not_active Abandoned
-
2025
- 2025-04-03 JP JP2025061793A patent/JP2025106387A/ja active Pending
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