JP2020509780A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020509780A5 JP2020509780A5 JP2019552206A JP2019552206A JP2020509780A5 JP 2020509780 A5 JP2020509780 A5 JP 2020509780A5 JP 2019552206 A JP2019552206 A JP 2019552206A JP 2019552206 A JP2019552206 A JP 2019552206A JP 2020509780 A5 JP2020509780 A5 JP 2020509780A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- stem cell
- genetically engineered
- hla
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022160907A JP7731579B2 (ja) | 2017-03-20 | 2022-10-05 | 細胞並びにその使用方法及び製造方法 |
| JP2025134751A JP2025169335A (ja) | 2017-03-20 | 2025-08-13 | 細胞並びにその使用方法及び製造方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762473564P | 2017-03-20 | 2017-03-20 | |
| US62/473,564 | 2017-03-20 | ||
| PCT/US2018/023288 WO2018175390A1 (en) | 2017-03-20 | 2018-03-20 | Cells and methods of uses and making the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022160907A Division JP7731579B2 (ja) | 2017-03-20 | 2022-10-05 | 細胞並びにその使用方法及び製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020509780A JP2020509780A (ja) | 2020-04-02 |
| JP2020509780A5 true JP2020509780A5 (https=) | 2021-04-30 |
Family
ID=63585747
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019552206A Pending JP2020509780A (ja) | 2017-03-20 | 2018-03-20 | 細胞並びにその使用方法及び製造方法 |
| JP2022160907A Active JP7731579B2 (ja) | 2017-03-20 | 2022-10-05 | 細胞並びにその使用方法及び製造方法 |
| JP2025134751A Pending JP2025169335A (ja) | 2017-03-20 | 2025-08-13 | 細胞並びにその使用方法及び製造方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022160907A Active JP7731579B2 (ja) | 2017-03-20 | 2022-10-05 | 細胞並びにその使用方法及び製造方法 |
| JP2025134751A Pending JP2025169335A (ja) | 2017-03-20 | 2025-08-13 | 細胞並びにその使用方法及び製造方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20200095543A1 (https=) |
| EP (1) | EP3601528A4 (https=) |
| JP (3) | JP2020509780A (https=) |
| CN (2) | CN119120363A (https=) |
| AU (2) | AU2018239320B2 (https=) |
| CA (1) | CA3094322A1 (https=) |
| WO (1) | WO2018175390A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11793833B2 (en) | 2016-12-02 | 2023-10-24 | Juno Therapeutics, Inc. | Engineered B cells and related compositions and methods |
| CN109234232A (zh) * | 2018-09-30 | 2019-01-18 | 杭州华安单抗生物技术有限公司 | 兔外周血b细胞的培养体系及培养方法、抗体的制备方法和应用 |
| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
| US20220267732A1 (en) | 2019-08-01 | 2022-08-25 | Sana Biotechnology, Inc. | Dux4 expressing cells and uses thereof |
| JP7728747B2 (ja) | 2019-08-23 | 2025-08-25 | サナ バイオテクノロジー,インコーポレイテッド | Cd24発現細胞およびそれらの用途 |
| AU2020364139A1 (en) * | 2019-10-10 | 2022-05-26 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Modified stem cells and methods of use thereof |
| WO2021102324A1 (en) * | 2019-11-20 | 2021-05-27 | Vita Therapeutics, Inc. | Method of engineering hypoimmunogenic muscle precursor cells |
| KR20220158046A (ko) * | 2020-03-25 | 2022-11-29 | 사나 바이오테크놀로지, 인크. | 신경계 장애 및 병태의 치료를 위한 면역저하성 신경 세포 |
| CN111548998B (zh) * | 2020-04-23 | 2022-08-05 | 中山大学 | 一种分泌pd-1抗体的长寿浆细胞及其制备方法与应用 |
| AU2021262766A1 (en) * | 2020-04-27 | 2022-11-24 | Sana Biotechnology, Inc. | Repeat dosing of hypoimmunogenic cells |
| CN111849909A (zh) * | 2020-06-03 | 2020-10-30 | 暨南大学 | 一种用于快速高效扩增人b淋巴细胞体外扩增的细胞及其构建方法 |
| WO2021251271A1 (ja) * | 2020-06-09 | 2021-12-16 | 帝人株式会社 | Mhc-クラスi発現が抑制された細胞 |
| CN114015656A (zh) * | 2020-07-15 | 2022-02-08 | 南京北恒生物科技有限公司 | 用于同种异体移植的工程化免疫细胞 |
| US20230248768A1 (en) * | 2020-07-15 | 2023-08-10 | Nanjing Bioheng Biotech Co., Ltd | Engineered immune cell for allotransplantation |
| CN114457024A (zh) * | 2020-10-30 | 2022-05-10 | 未来智人再生医学研究院(广州)有限公司 | 一种表达IL-4Rα阻断物的多能干细胞或其衍生物及应用 |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| KR20230118887A (ko) | 2020-12-03 | 2023-08-14 | 센츄리 쎄라퓨틱스 인코포레이티드 | 유전자 조작 세포 및 이의 용도 |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| AR124414A1 (es) | 2020-12-18 | 2023-03-22 | Century Therapeutics Inc | Sistema de receptor de antígeno quimérico con especificidad de receptor adaptable |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| JP2024501971A (ja) | 2020-12-31 | 2024-01-17 | サナ バイオテクノロジー,インコーポレイテッド | Car-t活性を調節するための方法及び組成物 |
| WO2022242359A1 (zh) * | 2021-05-20 | 2022-11-24 | 中国科学院广州生物医药与健康研究院 | 一种体液免疫系统再生的方法及其应用 |
| CN114181968B (zh) * | 2022-02-11 | 2022-07-19 | 北京干细胞与再生医学研究院 | 一种具备b谱系分化潜能的人造血祖细胞的制备方法及其应用 |
| US20250302953A1 (en) | 2022-02-14 | 2025-10-02 | Sana Biotechnology, Inc. | Methods of treating patients exhibiting a prior failed therapy with hypoimmunogenic cells |
| US20260002124A1 (en) | 2022-07-01 | 2026-01-01 | Novo Nordisk A/S | Enhancing neuronal differentiation of ventral midbrain neural progenitor cells |
| CN116008564B (zh) * | 2023-01-09 | 2025-07-22 | 中南大学湘雅二医院 | 检测2-nbdg阳性b细胞的试剂在制备诊断和/或预后自身免疫糖尿病制剂中的应用 |
| WO2024169917A1 (zh) * | 2023-02-16 | 2024-08-22 | 士泽生物医药(苏州)有限公司 | 通用型细胞及其制备方法 |
| KR20260010740A (ko) * | 2023-05-12 | 2026-01-21 | 주식회사 엔케이젠바이오텍코리아 | 확장된 자연 살해 세포를 이용한 알츠하이머병 치료 방법 |
| EP4735585A1 (en) | 2023-06-30 | 2026-05-06 | Novo Nordisk A/S | Enhancing neuronal differentiation of neural progenitor cells |
| WO2025096757A1 (en) | 2023-11-01 | 2025-05-08 | Sana Biotechnology, Inc. | Hypoimmunogenic cd22-targeted car t cells for the treatment of relapsed and/or refractory b cell lymphomas |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5573940A (en) * | 1989-06-12 | 1996-11-12 | Oklahoma Medical Research Foundation | Cells expressing high levels of CD59 |
| IL162130A0 (en) * | 2001-12-07 | 2005-11-20 | Robarts Res Inst | Hematopoietic cells from human embryonic stem cells |
| GB2398783A (en) * | 2003-02-26 | 2004-09-01 | Antonio Lanzavecchia | A method for producing immortalised human B memory lymphocytes |
| EP2289534B1 (en) * | 2004-04-05 | 2017-08-30 | The Regents of The University of California | NKG2D antibodies for use in the treatment of rheumatoid arthritis or Crohn's disease |
| EP2147594B1 (en) * | 2008-06-27 | 2013-11-13 | Merus B.V. | Antibody producing non-human mammals |
| WO2013086029A1 (en) * | 2011-12-05 | 2013-06-13 | Primorigen Biosciences Inc. | Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof |
| FI2838548T3 (fi) * | 2012-04-17 | 2023-10-02 | Univ Washington Through Its Center For Commercialization | HLA:n luokan II puutteelliset solut, HLA:n luokan II puutteelliset solut, jotka kykenevät ilmentämään HLA:n luokan II proteiineja, ja niiden käytöt |
| CN104046593A (zh) * | 2013-03-14 | 2014-09-17 | 浙江大学 | 一种低免疫原性的人细胞及其制备方法 |
| US10034463B2 (en) * | 2014-01-24 | 2018-07-31 | Children's Medical Center Corporation | High-throughput mouse model for optimizing antibody affinities |
| CN116059378A (zh) * | 2014-12-10 | 2023-05-05 | 明尼苏达大学董事会 | 用于治疗疾病的遗传修饰的细胞、组织和器官 |
| CN107921148A (zh) * | 2015-05-08 | 2018-04-17 | 哈佛学院校长同事会 | 通用供体干细胞和相关方法 |
| KR20250141836A (ko) * | 2015-11-04 | 2025-09-29 | 페이트 세러퓨틱스, 인코포레이티드 | 만능 세포의 유전자 조작 |
| JP2020505025A (ja) * | 2017-01-13 | 2020-02-20 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 免疫工学的な改変をした多能性細胞 |
| US20190381157A1 (en) * | 2017-01-29 | 2019-12-19 | Zequn Tang | Methods of immune modulation against foreign and/or auto antigens |
-
2018
- 2018-03-20 CA CA3094322A patent/CA3094322A1/en active Pending
- 2018-03-20 EP EP18771866.3A patent/EP3601528A4/en active Pending
- 2018-03-20 WO PCT/US2018/023288 patent/WO2018175390A1/en not_active Ceased
- 2018-03-20 CN CN202411279640.0A patent/CN119120363A/zh active Pending
- 2018-03-20 CN CN201880032723.6A patent/CN110637083A/zh active Pending
- 2018-03-20 JP JP2019552206A patent/JP2020509780A/ja active Pending
- 2018-03-20 AU AU2018239320A patent/AU2018239320B2/en active Active
- 2018-03-30 US US16/495,318 patent/US20200095543A1/en not_active Abandoned
-
2022
- 2022-10-05 JP JP2022160907A patent/JP7731579B2/ja active Active
-
2023
- 2023-02-03 US US18/164,502 patent/US20230313131A1/en active Pending
-
2025
- 2025-01-23 AU AU2025200450A patent/AU2025200450A1/en active Pending
- 2025-08-13 JP JP2025134751A patent/JP2025169335A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020509780A5 (https=) | ||
| JP2022188202A (ja) | 細胞並びにその使用方法及び製造方法 | |
| JP7649258B2 (ja) | 癌を治療するための組成物および方法 | |
| JP6866988B2 (ja) | 誘導された樹状細胞およびその使用 | |
| US10059923B2 (en) | Methods for off-the-shelf tumor immunotherapy using allogeneic T-cell precursors | |
| JP2021530999A5 (https=) | ||
| JP2020108398A (ja) | Car発現ベクター及びcar発現t細胞 | |
| KR20160068960A (ko) | 면역요법을 위한 다클론성 감마 델타 t 세포 | |
| US20050238626A1 (en) | Antigen specific T cell therapy | |
| JP2023501388A5 (https=) | ||
| WO2017220704A1 (en) | Genetically modified t lymphocytes | |
| WO2019154313A1 (zh) | 一种分离的嵌合抗原受体以及包含其的修饰t细胞及用途 | |
| CN116348496A (zh) | Bcma嵌合抗原受体 | |
| JP2023532917A (ja) | B細胞のb2m遺伝子座を編集するための方法および組成物 | |
| Brehm et al. | Humanized mice in translational immunology | |
| CN117106061B (zh) | 靶向巨细胞病毒抗原的tcr和表达其的t细胞及应用 | |
| CN117987435A (zh) | 氧依赖性嵌合抗原受体表达及其应用 | |
| US20190307800A1 (en) | Methods for off-the-shelf-tumor immunotherapy using allogeneic t-cell precursors | |
| CN111499766B (zh) | 针对慢性淋巴细胞白血病的免疫效应细胞、其制备方法和应用 | |
| Arjomandnejad et al. | CAR-T regulatory (CAR-Treg) cells: engineering and applications. Biomedicines 2022; 10: 287 | |
| CN117736300A (zh) | 靶向巨细胞病毒pp65的T细胞受体和表达其的T细胞及应用 | |
| US20230272431A1 (en) | Methods and compositions for editing the b2m locus in b cells | |
| US20250025499A1 (en) | T cell immunotherapy for hematologic malignancies having an sf3b1 mutation | |
| EP2953644B1 (en) | Induced dendritic cells and uses thereof | |
| WO2025232819A1 (en) | Immunotherapies using engineered cells for enhanced bone marrow homing |