JP2020509072A5 - - Google Patents
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- JP2020509072A5 JP2020509072A5 JP2019548652A JP2019548652A JP2020509072A5 JP 2020509072 A5 JP2020509072 A5 JP 2020509072A5 JP 2019548652 A JP2019548652 A JP 2019548652A JP 2019548652 A JP2019548652 A JP 2019548652A JP 2020509072 A5 JP2020509072 A5 JP 2020509072A5
- Authority
- JP
- Japan
- Prior art keywords
- vitamin
- composition
- use according
- parts
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 description 15
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 14
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 7
- 229930003268 Vitamin C Natural products 0.000 description 7
- 229930003231 vitamin Natural products 0.000 description 7
- 235000013343 vitamin Nutrition 0.000 description 7
- 239000011782 vitamin Substances 0.000 description 7
- 229940088594 vitamin Drugs 0.000 description 7
- 235000019154 vitamin C Nutrition 0.000 description 7
- 239000011718 vitamin C Substances 0.000 description 7
- 235000019156 vitamin B Nutrition 0.000 description 6
- 239000011720 vitamin B Substances 0.000 description 6
- 150000003722 vitamin derivatives Chemical class 0.000 description 6
- 229930003270 Vitamin B Natural products 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 239000000825 pharmaceutical preparation Substances 0.000 description 3
- 229940127557 pharmaceutical product Drugs 0.000 description 3
- 208000024827 Alzheimer disease Diseases 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 1
- QWJSAWXRUVVRLH-LREBCSMRSA-M 2-hydroxyethyl(trimethyl)azanium;(2r,3r)-2,3,4-trihydroxy-4-oxobutanoate Chemical compound C[N+](C)(C)CCO.OC(=O)[C@H](O)[C@@H](O)C([O-])=O QWJSAWXRUVVRLH-LREBCSMRSA-M 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 229930003779 Vitamin B12 Natural products 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 229930003537 Vitamin B3 Natural products 0.000 description 1
- 229930003571 Vitamin B5 Natural products 0.000 description 1
- 229930003756 Vitamin B7 Natural products 0.000 description 1
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 description 1
- 229960002079 calcium pantothenate Drugs 0.000 description 1
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N nicotinic acid amide Natural products NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 1
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000019163 vitamin B12 Nutrition 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019160 vitamin B3 Nutrition 0.000 description 1
- 239000011708 vitamin B3 Substances 0.000 description 1
- 235000009492 vitamin B5 Nutrition 0.000 description 1
- 239000011675 vitamin B5 Substances 0.000 description 1
- 235000019158 vitamin B6 Nutrition 0.000 description 1
- 239000011726 vitamin B6 Substances 0.000 description 1
- 235000011912 vitamin B7 Nutrition 0.000 description 1
- 239000011735 vitamin B7 Substances 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022172956A JP2023011769A (ja) | 2017-03-07 | 2022-10-28 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
| JP2024198677A JP2025024089A (ja) | 2017-03-07 | 2024-11-14 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710131111.X | 2017-03-07 | ||
| CN201710131111.XA CN108567792A (zh) | 2017-03-07 | 2017-03-07 | 一种治疗阿尔茨海默病的复合维生素组合物 |
| PCT/CN2018/077107 WO2018161808A1 (zh) | 2017-03-07 | 2018-02-24 | 维生素组合物在制备用于预防、治疗或延迟阿尔茨海默病的药物中的用途 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022172956A Division JP2023011769A (ja) | 2017-03-07 | 2022-10-28 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020509072A JP2020509072A (ja) | 2020-03-26 |
| JP2020509072A5 true JP2020509072A5 (OSRAM) | 2021-04-08 |
| JP7169285B2 JP7169285B2 (ja) | 2022-11-10 |
Family
ID=63448062
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019548652A Active JP7169285B2 (ja) | 2017-03-07 | 2018-02-24 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
| JP2022172956A Pending JP2023011769A (ja) | 2017-03-07 | 2022-10-28 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
| JP2024198677A Pending JP2025024089A (ja) | 2017-03-07 | 2024-11-14 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022172956A Pending JP2023011769A (ja) | 2017-03-07 | 2022-10-28 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
| JP2024198677A Pending JP2025024089A (ja) | 2017-03-07 | 2024-11-14 | アルツハイマー病を予防し、治療し、又は遅延させるための薬物の調製におけるビタミン組成物の使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US11464797B2 (OSRAM) |
| EP (2) | EP3593805B1 (OSRAM) |
| JP (3) | JP7169285B2 (OSRAM) |
| CN (2) | CN108567792A (OSRAM) |
| AU (2) | AU2018229920B2 (OSRAM) |
| BR (1) | BR112019018652A2 (OSRAM) |
| CA (1) | CA3054972A1 (OSRAM) |
| ES (1) | ES2989651T3 (OSRAM) |
| WO (1) | WO2018161808A1 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20220041179A (ko) * | 2019-08-02 | 2022-03-31 | 상하이 레이징 파마수티컬 씨오., 엘티디. | 알츠하이머병의 표적으로 tpk 적용 |
| KR102275981B1 (ko) * | 2020-03-31 | 2021-07-13 | 고려은단주식회사 | 섬쑥부쟁이 추출물과 비타민 b 복합체의 혼합물을 포함하는 인지기능 개선용 조성물 |
| AU2022464309A1 (en) * | 2022-06-22 | 2025-01-23 | Biomedical Research Group Inc. | Prophylactic drug and therapeutic drug for diabetes-associated dementia |
| CN119055674B (zh) * | 2024-11-06 | 2025-02-18 | 中国医学科学院北京协和医院 | 一种可改善认知的组合物及其在阿尔茨海默病防治中的应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5626884A (en) | 1995-08-18 | 1997-05-06 | Lockett; Curtis G. | Treatment of sickle cell disease |
| JP2002517454A (ja) | 1998-06-10 | 2002-06-18 | アルバート ビー クラム | 健康保護性腸管ミクロフローラの創造／維持及び免疫系の増強のための予防的及び治療的栄養サプリメント |
| AU2003218319A1 (en) | 2002-03-22 | 2003-10-13 | Doc's Guide, Inc. | Multivitamin and mineral nutritional supplement |
| CA2583972A1 (en) | 2004-10-14 | 2006-10-19 | Adventures Plus Pty Ltd | A method for the treatment of gastrointestinal and other disorders with an admixture of vitamins and minerals |
| US20060148727A1 (en) | 2004-12-01 | 2006-07-06 | Curt Hendrix | Folate based composition for neurological and cognitive applications |
| US20110275591A1 (en) * | 2004-12-01 | 2011-11-10 | Concourse Health Sciences Llc | Cocktail for modulation of alzheimer's disease |
| CN101765427A (zh) | 2007-06-26 | 2010-06-30 | N.V.努特里奇亚 | 在简易精神状态检查值为24-26的受试者中改善记忆 |
| US9763989B2 (en) * | 2007-08-03 | 2017-09-19 | Shaklee Corporation | Nutritional supplement system |
| JP4206428B1 (ja) | 2008-06-09 | 2009-01-14 | 正樹 今川 | 認知症を処置するための組成物及びその利用 |
| KR20110004691A (ko) * | 2009-07-08 | 2011-01-14 | 대한민국(농촌진흥청장) | 뇌기능 개선효과를 가지는 붉나무 추출물을 포함하는 약학조성물 및 건강식품조성물 |
| US20130136800A1 (en) * | 2010-03-31 | 2013-05-30 | Vegenat, S.A. | Enteral Or Oral Food Product Intended, In Particular, For nutrition And For The Prevention And Improvement Of Neurological Alterations, Neurodegenerative Alterations or Cognitive Disorders |
| CN102843922B (zh) * | 2010-05-13 | 2015-12-16 | 尼特罗米加公司 | 硝基脂肪酸–认知减退的神经保护和/或抑制 |
| CN103327986B (zh) | 2010-07-22 | 2018-05-25 | 雷文制药有限公司 | 包含使用磁偶极子稳定化溶液的治疗或改善疾病并增强表现的方法 |
| KR20130015932A (ko) | 2011-08-05 | 2013-02-14 | 연세대학교 산학협력단 | 저용량의 치아졸리딘다이온을 포함하는 알츠하이머 병 치료용 약학조성물 |
| WO2013066151A1 (en) | 2011-10-31 | 2013-05-10 | N.V. Nutricia | Improving recognition |
| EP2819681A1 (en) * | 2012-03-02 | 2015-01-07 | N.V. Nutricia | Method for improving functional synaptic connectivity |
| JP2015524477A (ja) | 2012-08-07 | 2015-08-24 | バック・インスティテュート・フォー・リサーチ・オン・エイジング | 神経機能を改善するための多成分製剤 |
| US10894062B2 (en) * | 2012-08-10 | 2021-01-19 | Aquavit Pharmaceuticals, Inc. | Vitamin supplement compositions for injection |
| CN110840895A (zh) | 2013-07-23 | 2020-02-28 | 上海泽生科技开发股份有限公司 | 使用维生素b组合物促进胃肠系统动力的方法 |
| CN104256652A (zh) | 2014-10-08 | 2015-01-07 | 李明刚 | 一种口服复合维生素纳米脂质体 |
| CN104922164B (zh) | 2014-12-12 | 2020-06-02 | 中国医科大学 | 一种治疗阿尔茨海默病的药物复合制剂 |
| CN106265696A (zh) * | 2015-06-12 | 2017-01-04 | 上海泽生科技开发有限公司 | 使用复合维生素b、c组合物促进胃肠系统动力的方法 |
| CN104856048A (zh) | 2015-06-18 | 2015-08-26 | 安徽医联大成医药科技有限公司 | 一种促进肠胃蠕动的食品配方及其制备方法 |
| CN108079008A (zh) * | 2016-11-23 | 2018-05-29 | 上海泽生科技开发股份有限公司 | 促进胃肠系统动力的复合维生素组合物 |
-
2017
- 2017-03-07 CN CN201710131111.XA patent/CN108567792A/zh active Pending
-
2018
- 2018-02-24 EP EP18763903.4A patent/EP3593805B1/en active Active
- 2018-02-24 EP EP24189913.7A patent/EP4461361A3/en not_active Withdrawn
- 2018-02-24 AU AU2018229920A patent/AU2018229920B2/en active Active
- 2018-02-24 CA CA3054972A patent/CA3054972A1/en not_active Abandoned
- 2018-02-24 US US16/491,560 patent/US11464797B2/en active Active
- 2018-02-24 BR BR112019018652A patent/BR112019018652A2/pt not_active Application Discontinuation
- 2018-02-24 JP JP2019548652A patent/JP7169285B2/ja active Active
- 2018-02-24 CN CN201880015481.XA patent/CN110520135A/zh active Pending
- 2018-02-24 WO PCT/CN2018/077107 patent/WO2018161808A1/zh not_active Ceased
- 2018-02-24 ES ES18763903T patent/ES2989651T3/es active Active
-
2022
- 2022-09-15 US US17/945,684 patent/US20230248756A1/en not_active Abandoned
- 2022-10-28 JP JP2022172956A patent/JP2023011769A/ja active Pending
-
2024
- 2024-04-24 AU AU2024202678A patent/AU2024202678A1/en active Pending
- 2024-11-14 JP JP2024198677A patent/JP2025024089A/ja active Pending
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