JP2020506395A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020506395A5 JP2020506395A5 JP2019543232A JP2019543232A JP2020506395A5 JP 2020506395 A5 JP2020506395 A5 JP 2020506395A5 JP 2019543232 A JP2019543232 A JP 2019543232A JP 2019543232 A JP2019543232 A JP 2019543232A JP 2020506395 A5 JP2020506395 A5 JP 2020506395A5
- Authority
- JP
- Japan
- Prior art keywords
- target
- sample
- label
- labeling
- detectable label
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003795 chemical substances by application Substances 0.000 claims description 44
- 238000002372 labelling Methods 0.000 claims description 43
- 238000000034 method Methods 0.000 claims description 41
- 238000001514 detection method Methods 0.000 claims description 38
- 239000000126 substance Substances 0.000 claims description 22
- 108090000790 Enzymes Proteins 0.000 claims description 20
- 102000004190 Enzymes Human genes 0.000 claims description 20
- 239000003112 inhibitor Substances 0.000 claims description 19
- 239000002516 radical scavenger Substances 0.000 claims description 18
- 239000012634 fragment Substances 0.000 claims description 11
- 230000000694 effects Effects 0.000 claims description 10
- 238000003018 immunoassay Methods 0.000 claims description 8
- 239000000758 substrate Substances 0.000 claims description 8
- 239000007790 solid phase Substances 0.000 claims description 6
- 239000003153 chemical reaction reagent Substances 0.000 claims description 4
- 239000007850 fluorescent dye Substances 0.000 claims description 4
- 102000034287 fluorescent proteins Human genes 0.000 claims description 4
- 108091006047 fluorescent proteins Proteins 0.000 claims description 4
- 230000007306 turnover Effects 0.000 claims description 4
- 238000004020 luminiscence type Methods 0.000 claims description 3
- 230000001225 therapeutic effect Effects 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 2
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 3
- 239000012491 analyte Substances 0.000 claims 2
- 230000008685 targeting Effects 0.000 claims 2
- 229960005395 cetuximab Drugs 0.000 description 6
- 108700043045 nanoluc Proteins 0.000 description 5
- 238000003556 assay Methods 0.000 description 2
- 238000003776 cleavage reaction Methods 0.000 description 1
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 description 1
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762456906P | 2017-02-09 | 2017-02-09 | |
| US62/456,906 | 2017-02-09 | ||
| PCT/US2018/017540 WO2018148489A1 (en) | 2017-02-09 | 2018-02-09 | Analyte detection immunoassay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020506395A JP2020506395A (ja) | 2020-02-27 |
| JP2020506395A5 true JP2020506395A5 (https=) | 2021-03-11 |
| JP7141405B2 JP7141405B2 (ja) | 2022-09-22 |
Family
ID=63037133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019543232A Active JP7141405B2 (ja) | 2017-02-09 | 2018-02-09 | 検体検出イムノアッセイ |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US11327072B2 (https=) |
| EP (1) | EP3580563A4 (https=) |
| JP (1) | JP7141405B2 (https=) |
| WO (1) | WO2018148489A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202110773RA (en) * | 2019-04-10 | 2021-10-28 | Promega Corp | Compositions and methods for analyte detection using bioluminescence |
| JP7380341B2 (ja) * | 2020-03-06 | 2023-11-15 | 横河電機株式会社 | 図面管理装置、図面管理システム、図面管理方法、及びプログラム |
| WO2023250155A1 (en) * | 2022-06-24 | 2023-12-28 | Trustees Of Tufts College | Compositions and assays for opioid detection |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988001058A1 (en) * | 1986-08-06 | 1988-02-11 | Roger Philip Ekins | Determination of analyte concentration using two labelling markers |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| ATE87659T1 (de) | 1986-09-02 | 1993-04-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| EP0312565B1 (en) * | 1987-04-29 | 1993-03-03 | Celltech Limited | Binding assay device |
| US5104793A (en) * | 1988-02-16 | 1992-04-14 | Boehringer Mannheim Corporation | Method for determining an analyte in a liquid sample using a zoned test device and an inhibitor for a label used in said method |
| JP2576910B2 (ja) * | 1990-04-13 | 1997-01-29 | 富士写真フイルム株式会社 | 免疫分析要素および免疫分析方法 |
| GB9326451D0 (en) * | 1993-12-24 | 1994-02-23 | Multilyte Ltd | Binding assay |
| WO2002084283A2 (en) * | 2001-04-10 | 2002-10-24 | Nmi Naturwissenschaftliches Und Medizinisches Institut An Der Universität Tübingen In Reutlingen Stiftung Bürgerlichen Rechts | Method for determining analyte molecules in a sample |
| WO2003023360A2 (en) | 2001-09-10 | 2003-03-20 | Meso Scale Technologies, Llc | Methods and apparatus for conducting multiple measurements on a sample |
| CA2501873A1 (en) * | 2002-10-11 | 2004-04-22 | The Regents Of The University Of California | A method for diagnosis and prognosis of multiple sclerosis |
| JP4485470B2 (ja) | 2002-12-23 | 2010-06-23 | プロメガ コーポレイション | ルシフェラーゼ酵素活性を保護するための方法及びキット |
| EP1594962B1 (en) | 2003-01-31 | 2014-08-27 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US20050069958A1 (en) * | 2003-09-26 | 2005-03-31 | Mills Rhonda A. | Method for simultaneous evaluation of a sample containing a cellular target and a soluble analyte |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| US8492098B2 (en) * | 2006-02-21 | 2013-07-23 | The Trustees Of Tufts College | Methods and arrays for target analyte detection and determination of reaction components that affect a reaction |
| SE533515C2 (sv) * | 2008-04-16 | 2010-10-12 | Aamic Ab | Analysförfarande för samtidig analys av flera analyter |
| US9157910B2 (en) | 2013-03-15 | 2015-10-13 | Abbott Laboratories | Assay with increased dynamic range |
| WO2016090244A2 (en) | 2014-12-05 | 2016-06-09 | Mbio Diagnostics, Inc. | Methods and devices for performing high dynamic range immunoassays |
| ES2761427T3 (es) * | 2014-12-18 | 2020-05-19 | Hoffmann La Roche | Procedimientos para reducir interferencias |
| WO2016210294A1 (en) | 2015-06-25 | 2016-12-29 | Promega Corporation | Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases |
-
2018
- 2018-02-09 US US15/892,557 patent/US11327072B2/en active Active
- 2018-02-09 EP EP18751757.8A patent/EP3580563A4/en active Pending
- 2018-02-09 WO PCT/US2018/017540 patent/WO2018148489A1/en not_active Ceased
- 2018-02-09 JP JP2019543232A patent/JP7141405B2/ja active Active
-
2022
- 2022-04-26 US US17/729,829 patent/US12596119B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US12566186B2 (en) | Assays for detecting the presence or amount of an anti-drug antibody | |
| Hayrapetyan et al. | Enzyme-linked immunosorbent assay: types and applications | |
| JP6452718B2 (ja) | 食物アレルギーを検出するためのペプチド、試薬及び方法 | |
| JP5675597B2 (ja) | 大麻の使用の検出 | |
| CN113474657B (zh) | 使用微粒去除非特异性结合信号的方法 | |
| CN100420947C (zh) | 用单一捕获剂定量检测特异性分析物的方法及其试剂盒 | |
| JP6810055B2 (ja) | イムノアッセイにおける試験プローブおよび試薬の再利用方法 | |
| EP3111218B1 (en) | Protein l based bioassay method for determining presence of soluble antibodies in a sample and kit therefor | |
| Gao et al. | Rolling circle amplification integrated with suspension bead array for ultrasensitive multiplex immunodetection of tumor markers | |
| US20170138937A1 (en) | Detection of analytes | |
| US12596119B2 (en) | Analyte detection immunoassay | |
| JP2020506395A5 (https=) | ||
| CN111351924B (zh) | 一种基于酶诱导磷酸根离子激活的近红外荧光免疫分析试剂盒及检测方法 | |
| CN109781972B (zh) | 一种免疫定量检测方法和应用 | |
| JP2019138777A5 (https=) | ||
| KR102047978B1 (ko) | 측방유동 면역 분석 기반의 항ccp 항체 및 류마티스인자를 이용한 류마티스 관절염 진단 방법 | |
| Son et al. | Strategies for the optimization of bead-immunoassays for the effective detection of target biomolecules | |
| CN106771189B (zh) | 一种油佐剂疫苗的快速定性定量检测方法 | |
| CN104995512A (zh) | 用于可溶性成纤维细胞生长因子受体的灵敏的多重免疫测定 | |
| Bürgler | Strategy to follow-up and validate hits from phenotypic screening by cellular thermal shift assay coupled with mass spectrometry (CETSA-MS) | |
| AU2024283078A1 (en) | Antigen detection | |
| KR20180023563A (ko) | 측방유동 면역 분석 기반의 항ccp 항체 및 류마티스인자를 이용한 류마티스 관절염 진단 방법 | |
| WO2025035371A1 (zh) | 检测大尺寸cTnITC的组合物、试剂盒和方法、及其应用 | |
| HK40089494A (en) | Assays for detecting the presence or amount of an anti-drug antibody | |
| HK40089494B (en) | Assays for detecting the presence or amount of an anti-drug antibody |