JP2020506395A5 - - Google Patents
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- Publication number
- JP2020506395A5 JP2020506395A5 JP2019543232A JP2019543232A JP2020506395A5 JP 2020506395 A5 JP2020506395 A5 JP 2020506395A5 JP 2019543232 A JP2019543232 A JP 2019543232A JP 2019543232 A JP2019543232 A JP 2019543232A JP 2020506395 A5 JP2020506395 A5 JP 2020506395A5
- Authority
- JP
- Japan
- Prior art keywords
- target
- sample
- label
- labeling
- detectable label
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000003795 chemical substances by application Substances 0.000 claims description 44
- 238000002372 labelling Methods 0.000 claims description 43
- 238000000034 method Methods 0.000 claims description 41
- 238000001514 detection method Methods 0.000 claims description 38
- 239000000126 substance Substances 0.000 claims description 22
- 108090000790 Enzymes Proteins 0.000 claims description 20
- 102000004190 Enzymes Human genes 0.000 claims description 20
- 239000003112 inhibitor Substances 0.000 claims description 19
- 239000002516 radical scavenger Substances 0.000 claims description 18
- 239000012634 fragment Substances 0.000 claims description 11
- 230000000694 effects Effects 0.000 claims description 10
- 238000003018 immunoassay Methods 0.000 claims description 8
- 239000000758 substrate Substances 0.000 claims description 8
- 239000007790 solid phase Substances 0.000 claims description 6
- 239000003153 chemical reaction reagent Substances 0.000 claims description 4
- 239000007850 fluorescent dye Substances 0.000 claims description 4
- 102000034287 fluorescent proteins Human genes 0.000 claims description 4
- 108091006047 fluorescent proteins Proteins 0.000 claims description 4
- 230000007306 turnover Effects 0.000 claims description 4
- 238000004020 luminiscence type Methods 0.000 claims description 3
- 230000001225 therapeutic effect Effects 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 2
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 238000005406 washing Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 3
- 239000012491 analyte Substances 0.000 claims 2
- 230000008685 targeting Effects 0.000 claims 2
- 229960005395 cetuximab Drugs 0.000 description 6
- 108700043045 nanoluc Proteins 0.000 description 5
- 238000003556 assay Methods 0.000 description 2
- 238000003776 cleavage reaction Methods 0.000 description 1
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 description 1
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762456906P | 2017-02-09 | 2017-02-09 | |
| US62/456,906 | 2017-02-09 | ||
| PCT/US2018/017540 WO2018148489A1 (en) | 2017-02-09 | 2018-02-09 | Analyte detection immunoassay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020506395A JP2020506395A (ja) | 2020-02-27 |
| JP2020506395A5 true JP2020506395A5 (https=) | 2021-03-11 |
| JP7141405B2 JP7141405B2 (ja) | 2022-09-22 |
Family
ID=63037133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019543232A Active JP7141405B2 (ja) | 2017-02-09 | 2018-02-09 | 検体検出イムノアッセイ |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US11327072B2 (https=) |
| EP (1) | EP3580563A4 (https=) |
| JP (1) | JP7141405B2 (https=) |
| WO (1) | WO2018148489A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021020354A2 (pt) * | 2019-04-10 | 2021-12-14 | Promega Corp | Composições e métodos para detecção de analito com o uso de bioluminescência |
| JP7380341B2 (ja) * | 2020-03-06 | 2023-11-15 | 横河電機株式会社 | 図面管理装置、図面管理システム、図面管理方法、及びプログラム |
| WO2023250155A1 (en) * | 2022-06-24 | 2023-12-28 | Trustees Of Tufts College | Compositions and assays for opioid detection |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU614935B2 (en) * | 1986-08-06 | 1991-09-19 | Multilyte Limited | Determination of analyte concentration using two labelling markers |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| EP0281604B1 (en) | 1986-09-02 | 1993-03-31 | Enzon Labs Inc. | Single polypeptide chain binding molecules |
| ATE86386T1 (de) * | 1987-04-29 | 1993-03-15 | Celltech Ltd | Vorrichtung fuer bindungstest. |
| US5104793A (en) * | 1988-02-16 | 1992-04-14 | Boehringer Mannheim Corporation | Method for determining an analyte in a liquid sample using a zoned test device and an inhibitor for a label used in said method |
| JP2576910B2 (ja) * | 1990-04-13 | 1997-01-29 | 富士写真フイルム株式会社 | 免疫分析要素および免疫分析方法 |
| GB9326451D0 (en) * | 1993-12-24 | 1994-02-23 | Multilyte Ltd | Binding assay |
| EP1377827A2 (en) * | 2001-04-10 | 2004-01-07 | NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen in Reutlingen Stiftung Bürgerlichen Rechts | Method for determining analyte molecules in a sample |
| AU2002341621A1 (en) | 2001-09-10 | 2003-03-24 | Meso Scale Technologies, Llc | Methods, reagents, kits and apparatus for protein function analysis |
| WO2004034031A2 (en) * | 2002-10-11 | 2004-04-22 | The Regents Of The University Of California | A method for diagnosis and prognosis of multiple sclerosis |
| JP4485470B2 (ja) | 2002-12-23 | 2010-06-23 | プロメガ コーポレイション | ルシフェラーゼ酵素活性を保護するための方法及びキット |
| EP2341134B1 (en) | 2003-01-31 | 2014-08-27 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US20050069958A1 (en) * | 2003-09-26 | 2005-03-31 | Mills Rhonda A. | Method for simultaneous evaluation of a sample containing a cellular target and a soluble analyte |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| US8492098B2 (en) * | 2006-02-21 | 2013-07-23 | The Trustees Of Tufts College | Methods and arrays for target analyte detection and determination of reaction components that affect a reaction |
| SE533515C2 (sv) | 2008-04-16 | 2010-10-12 | Aamic Ab | Analysförfarande för samtidig analys av flera analyter |
| US9157910B2 (en) | 2013-03-15 | 2015-10-13 | Abbott Laboratories | Assay with increased dynamic range |
| US10451615B2 (en) | 2014-12-05 | 2019-10-22 | Mbio Diagnostics, Inc. | Methods and devices for performing high dynamic range immunoassays |
| JP6850254B2 (ja) | 2014-12-18 | 2021-03-31 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 干渉を減少させるための方法 |
| CN107922428B (zh) * | 2015-06-25 | 2021-02-05 | 普洛麦格公司 | 噻吩并吡咯化合物及其作为刺虾源性荧光素酶的抑制剂的用途 |
-
2018
- 2018-02-09 EP EP18751757.8A patent/EP3580563A4/en active Pending
- 2018-02-09 US US15/892,557 patent/US11327072B2/en active Active
- 2018-02-09 WO PCT/US2018/017540 patent/WO2018148489A1/en not_active Ceased
- 2018-02-09 JP JP2019543232A patent/JP7141405B2/ja active Active
-
2022
- 2022-04-26 US US17/729,829 patent/US12596119B2/en active Active
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