JP7141405B2 - 検体検出イムノアッセイ - Google Patents
検体検出イムノアッセイ Download PDFInfo
- Publication number
- JP7141405B2 JP7141405B2 JP2019543232A JP2019543232A JP7141405B2 JP 7141405 B2 JP7141405 B2 JP 7141405B2 JP 2019543232 A JP2019543232 A JP 2019543232A JP 2019543232 A JP2019543232 A JP 2019543232A JP 7141405 B2 JP7141405 B2 JP 7141405B2
- Authority
- JP
- Japan
- Prior art keywords
- competitor
- antibody
- labeled
- binding
- signal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/534—Production of labelled immunochemicals with radioactive label
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762456906P | 2017-02-09 | 2017-02-09 | |
| US62/456,906 | 2017-02-09 | ||
| PCT/US2018/017540 WO2018148489A1 (en) | 2017-02-09 | 2018-02-09 | Analyte detection immunoassay |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020506395A JP2020506395A (ja) | 2020-02-27 |
| JP2020506395A5 JP2020506395A5 (https=) | 2021-03-11 |
| JP7141405B2 true JP7141405B2 (ja) | 2022-09-22 |
Family
ID=63037133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019543232A Active JP7141405B2 (ja) | 2017-02-09 | 2018-02-09 | 検体検出イムノアッセイ |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US11327072B2 (https=) |
| EP (1) | EP3580563A4 (https=) |
| JP (1) | JP7141405B2 (https=) |
| WO (1) | WO2018148489A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202110773RA (en) * | 2019-04-10 | 2021-10-28 | Promega Corp | Compositions and methods for analyte detection using bioluminescence |
| JP7380341B2 (ja) * | 2020-03-06 | 2023-11-15 | 横河電機株式会社 | 図面管理装置、図面管理システム、図面管理方法、及びプログラム |
| WO2023250155A1 (en) * | 2022-06-24 | 2023-12-28 | Trustees Of Tufts College | Compositions and assays for opioid detection |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040142392A1 (en) | 2001-04-10 | 2004-07-22 | Markus Templin | Method for determining analyte molecules in a sample |
| US20050009096A1 (en) | 2002-10-11 | 2005-01-13 | The Regents Of The University Of California | Method for diagnosis and prognosis of multiple sclerosis |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1988001058A1 (en) * | 1986-08-06 | 1988-02-11 | Roger Philip Ekins | Determination of analyte concentration using two labelling markers |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| ATE87659T1 (de) | 1986-09-02 | 1993-04-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| EP0312565B1 (en) * | 1987-04-29 | 1993-03-03 | Celltech Limited | Binding assay device |
| US5104793A (en) * | 1988-02-16 | 1992-04-14 | Boehringer Mannheim Corporation | Method for determining an analyte in a liquid sample using a zoned test device and an inhibitor for a label used in said method |
| JP2576910B2 (ja) * | 1990-04-13 | 1997-01-29 | 富士写真フイルム株式会社 | 免疫分析要素および免疫分析方法 |
| GB9326451D0 (en) * | 1993-12-24 | 1994-02-23 | Multilyte Ltd | Binding assay |
| WO2003023360A2 (en) | 2001-09-10 | 2003-03-20 | Meso Scale Technologies, Llc | Methods and apparatus for conducting multiple measurements on a sample |
| JP4485470B2 (ja) | 2002-12-23 | 2010-06-23 | プロメガ コーポレイション | ルシフェラーゼ酵素活性を保護するための方法及びキット |
| EP1594962B1 (en) | 2003-01-31 | 2014-08-27 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US20050069958A1 (en) * | 2003-09-26 | 2005-03-31 | Mills Rhonda A. | Method for simultaneous evaluation of a sample containing a cellular target and a soluble analyte |
| US7425436B2 (en) | 2004-07-30 | 2008-09-16 | Promega Corporation | Covalent tethering of functional groups to proteins and substrates therefor |
| US8492098B2 (en) * | 2006-02-21 | 2013-07-23 | The Trustees Of Tufts College | Methods and arrays for target analyte detection and determination of reaction components that affect a reaction |
| SE533515C2 (sv) * | 2008-04-16 | 2010-10-12 | Aamic Ab | Analysförfarande för samtidig analys av flera analyter |
| US9157910B2 (en) | 2013-03-15 | 2015-10-13 | Abbott Laboratories | Assay with increased dynamic range |
| WO2016090244A2 (en) | 2014-12-05 | 2016-06-09 | Mbio Diagnostics, Inc. | Methods and devices for performing high dynamic range immunoassays |
| ES2761427T3 (es) * | 2014-12-18 | 2020-05-19 | Hoffmann La Roche | Procedimientos para reducir interferencias |
| WO2016210294A1 (en) | 2015-06-25 | 2016-12-29 | Promega Corporation | Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases |
-
2018
- 2018-02-09 US US15/892,557 patent/US11327072B2/en active Active
- 2018-02-09 EP EP18751757.8A patent/EP3580563A4/en active Pending
- 2018-02-09 WO PCT/US2018/017540 patent/WO2018148489A1/en not_active Ceased
- 2018-02-09 JP JP2019543232A patent/JP7141405B2/ja active Active
-
2022
- 2022-04-26 US US17/729,829 patent/US12596119B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040142392A1 (en) | 2001-04-10 | 2004-07-22 | Markus Templin | Method for determining analyte molecules in a sample |
| US20050009096A1 (en) | 2002-10-11 | 2005-01-13 | The Regents Of The University Of California | Method for diagnosis and prognosis of multiple sclerosis |
Also Published As
| Publication number | Publication date |
|---|---|
| US11327072B2 (en) | 2022-05-10 |
| WO2018148489A1 (en) | 2018-08-16 |
| US12596119B2 (en) | 2026-04-07 |
| US20180224441A1 (en) | 2018-08-09 |
| EP3580563A1 (en) | 2019-12-18 |
| EP3580563A4 (en) | 2020-11-18 |
| US20220252585A1 (en) | 2022-08-11 |
| JP2020506395A (ja) | 2020-02-27 |
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