JP7141405B2 - 検体検出イムノアッセイ - Google Patents

検体検出イムノアッセイ Download PDF

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Publication number
JP7141405B2
JP7141405B2 JP2019543232A JP2019543232A JP7141405B2 JP 7141405 B2 JP7141405 B2 JP 7141405B2 JP 2019543232 A JP2019543232 A JP 2019543232A JP 2019543232 A JP2019543232 A JP 2019543232A JP 7141405 B2 JP7141405 B2 JP 7141405B2
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competitor
antibody
labeled
binding
signal
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Japanese (ja)
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JP2020506395A5 (https=
JP2020506395A (ja
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ニディー ナス
ロッド フレミング
マルジェタ ウラー
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Promega Corp
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Promega Corp
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/534Production of labelled immunochemicals with radioactive label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
JP2019543232A 2017-02-09 2018-02-09 検体検出イムノアッセイ Active JP7141405B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762456906P 2017-02-09 2017-02-09
US62/456,906 2017-02-09
PCT/US2018/017540 WO2018148489A1 (en) 2017-02-09 2018-02-09 Analyte detection immunoassay

Publications (3)

Publication Number Publication Date
JP2020506395A JP2020506395A (ja) 2020-02-27
JP2020506395A5 JP2020506395A5 (https=) 2021-03-11
JP7141405B2 true JP7141405B2 (ja) 2022-09-22

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019543232A Active JP7141405B2 (ja) 2017-02-09 2018-02-09 検体検出イムノアッセイ

Country Status (4)

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US (2) US11327072B2 (https=)
EP (1) EP3580563A4 (https=)
JP (1) JP7141405B2 (https=)
WO (1) WO2018148489A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202110773RA (en) * 2019-04-10 2021-10-28 Promega Corp Compositions and methods for analyte detection using bioluminescence
JP7380341B2 (ja) * 2020-03-06 2023-11-15 横河電機株式会社 図面管理装置、図面管理システム、図面管理方法、及びプログラム
WO2023250155A1 (en) * 2022-06-24 2023-12-28 Trustees Of Tufts College Compositions and assays for opioid detection

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142392A1 (en) 2001-04-10 2004-07-22 Markus Templin Method for determining analyte molecules in a sample
US20050009096A1 (en) 2002-10-11 2005-01-13 The Regents Of The University Of California Method for diagnosis and prognosis of multiple sclerosis

Family Cites Families (19)

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WO1988001058A1 (en) * 1986-08-06 1988-02-11 Roger Philip Ekins Determination of analyte concentration using two labelling markers
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
ATE87659T1 (de) 1986-09-02 1993-04-15 Enzon Lab Inc Bindungsmolekuele mit einzelpolypeptidkette.
EP0312565B1 (en) * 1987-04-29 1993-03-03 Celltech Limited Binding assay device
US5104793A (en) * 1988-02-16 1992-04-14 Boehringer Mannheim Corporation Method for determining an analyte in a liquid sample using a zoned test device and an inhibitor for a label used in said method
JP2576910B2 (ja) * 1990-04-13 1997-01-29 富士写真フイルム株式会社 免疫分析要素および免疫分析方法
GB9326451D0 (en) * 1993-12-24 1994-02-23 Multilyte Ltd Binding assay
WO2003023360A2 (en) 2001-09-10 2003-03-20 Meso Scale Technologies, Llc Methods and apparatus for conducting multiple measurements on a sample
JP4485470B2 (ja) 2002-12-23 2010-06-23 プロメガ コーポレイション ルシフェラーゼ酵素活性を保護するための方法及びキット
EP1594962B1 (en) 2003-01-31 2014-08-27 Promega Corporation Covalent tethering of functional groups to proteins
US20050069958A1 (en) * 2003-09-26 2005-03-31 Mills Rhonda A. Method for simultaneous evaluation of a sample containing a cellular target and a soluble analyte
US7425436B2 (en) 2004-07-30 2008-09-16 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor
US8492098B2 (en) * 2006-02-21 2013-07-23 The Trustees Of Tufts College Methods and arrays for target analyte detection and determination of reaction components that affect a reaction
SE533515C2 (sv) * 2008-04-16 2010-10-12 Aamic Ab Analysförfarande för samtidig analys av flera analyter
US9157910B2 (en) 2013-03-15 2015-10-13 Abbott Laboratories Assay with increased dynamic range
WO2016090244A2 (en) 2014-12-05 2016-06-09 Mbio Diagnostics, Inc. Methods and devices for performing high dynamic range immunoassays
ES2761427T3 (es) * 2014-12-18 2020-05-19 Hoffmann La Roche Procedimientos para reducir interferencias
WO2016210294A1 (en) 2015-06-25 2016-12-29 Promega Corporation Thienopyrrole compounds and uses thereof as inhibitors of oplophorus-derived luciferases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142392A1 (en) 2001-04-10 2004-07-22 Markus Templin Method for determining analyte molecules in a sample
US20050009096A1 (en) 2002-10-11 2005-01-13 The Regents Of The University Of California Method for diagnosis and prognosis of multiple sclerosis

Also Published As

Publication number Publication date
US11327072B2 (en) 2022-05-10
WO2018148489A1 (en) 2018-08-16
US12596119B2 (en) 2026-04-07
US20180224441A1 (en) 2018-08-09
EP3580563A1 (en) 2019-12-18
EP3580563A4 (en) 2020-11-18
US20220252585A1 (en) 2022-08-11
JP2020506395A (ja) 2020-02-27

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