JP2020506169A5 - - Google Patents
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- Publication number
- JP2020506169A5 JP2020506169A5 JP2019537351A JP2019537351A JP2020506169A5 JP 2020506169 A5 JP2020506169 A5 JP 2020506169A5 JP 2019537351 A JP2019537351 A JP 2019537351A JP 2019537351 A JP2019537351 A JP 2019537351A JP 2020506169 A5 JP2020506169 A5 JP 2020506169A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- component
- substituted
- unsubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- VFTRKSBEFQDZKX-UHFFFAOYSA-N 3,3'-diindolylmethane Chemical class C1=CC=C2C(CC=3C4=CC=CC=C4NC=3)=CNC2=C1 VFTRKSBEFQDZKX-UHFFFAOYSA-N 0.000 claims 5
- TWJAXIHBWPVMIR-UHFFFAOYSA-N diindolylmethane Natural products C1=CC=C2NC(CC=3NC4=CC=CC=C4C=3)=CC2=C1 TWJAXIHBWPVMIR-UHFFFAOYSA-N 0.000 claims 4
- 239000002253 acid Substances 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims 2
- 208000017520 skin disease Diseases 0.000 claims 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims 1
- 208000002874 Acne Vulgaris Diseases 0.000 claims 1
- 206010061218 Inflammation Diseases 0.000 claims 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 claims 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 claims 1
- 241001303601 Rosacea Species 0.000 claims 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims 1
- 206010000496 acne Diseases 0.000 claims 1
- 230000032683 aging Effects 0.000 claims 1
- 239000002552 dosage form Substances 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims 1
- 229960001285 quercetin Drugs 0.000 claims 1
- 235000005875 quercetin Nutrition 0.000 claims 1
- 201000004700 rosacea Diseases 0.000 claims 1
- 235000019155 vitamin A Nutrition 0.000 claims 1
- 239000011719 vitamin A Substances 0.000 claims 1
- -1 vitamin A compound Chemical class 0.000 claims 1
- 229940045997 vitamin a Drugs 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022127265A JP7481402B2 (ja) | 2017-01-20 | 2022-08-09 | 皮膚疾患の処置のための併用療法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762448808P | 2017-01-20 | 2017-01-20 | |
| US62/448,808 | 2017-01-20 | ||
| PCT/IB2018/000109 WO2018134683A1 (en) | 2017-01-20 | 2018-01-19 | Combination therapy for treatment of skin diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022127265A Division JP7481402B2 (ja) | 2017-01-20 | 2022-08-09 | 皮膚疾患の処置のための併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020506169A JP2020506169A (ja) | 2020-02-27 |
| JP2020506169A5 true JP2020506169A5 (https=) | 2021-03-04 |
| JP7123058B2 JP7123058B2 (ja) | 2022-08-22 |
Family
ID=61731720
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019537351A Active JP7123058B2 (ja) | 2017-01-20 | 2018-01-19 | 皮膚疾患の処置のための併用療法 |
| JP2022127265A Active JP7481402B2 (ja) | 2017-01-20 | 2022-08-09 | 皮膚疾患の処置のための併用療法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022127265A Active JP7481402B2 (ja) | 2017-01-20 | 2022-08-09 | 皮膚疾患の処置のための併用療法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11241467B2 (https=) |
| EP (1) | EP3570889A1 (https=) |
| JP (2) | JP7123058B2 (https=) |
| CN (2) | CN116036290A (https=) |
| AU (1) | AU2018209393B2 (https=) |
| BR (1) | BR112019014942A2 (https=) |
| CA (1) | CA3050208A1 (https=) |
| WO (1) | WO2018134683A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7169591B2 (ja) * | 2016-09-15 | 2022-11-11 | スキンテック ライフ サイエンス リミテッド | 皮膚疾患の処置のためのｄｉｍの舌下又は頬側の投与 |
| US11241467B2 (en) | 2017-01-20 | 2022-02-08 | Skintech Life Science Limited | Composition for treating acne |
| WO2025097063A1 (en) * | 2023-11-01 | 2025-05-08 | Skintech Life Science Limited | Topical dim compositions and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5665367A (en) * | 1996-09-27 | 1997-09-09 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Skin care compositions containing naringenin and/or quercetin and a retinoid |
| US6599913B1 (en) * | 2001-06-29 | 2003-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| US6767563B2 (en) * | 2001-10-30 | 2004-07-27 | Michael D. Farley | Immune functions |
| US20030166583A1 (en) * | 2002-02-22 | 2003-09-04 | Oliver Yoa-Pu Hu | Dermal cytochrome P450 1A inhibitors and enhancers |
| BRPI0717753B1 (pt) * | 2006-10-27 | 2022-04-12 | Bioresponse, Llc | Uso de uma composição compreendendo 50-250 mg de um ou mais indóis relacionados com dim e um ou mais agentes anti-protozoários, e, composição |
| FR2908604B1 (fr) * | 2006-11-16 | 2013-06-28 | Physcience | Complement alimentaire pour la prevention ou la lutte contre la chute des cheveux, l'acne, l'hirsutisme et la secretion sudorale apocrine excessive. |
| RU2419426C1 (ru) * | 2010-04-26 | 2011-05-27 | Всеволод Иванович Киселев | Лекарственное средство на основе дииндолилметана (dim) с повышенной биодоступностью и его использование в лечении гиперпластических и воспалительных заболеваний человека |
| GB201105050D0 (en) * | 2011-03-25 | 2011-05-11 | Iiaa Ltd | Pharmaceutical agent |
| EP2696868A1 (en) * | 2011-04-12 | 2014-02-19 | Nestec S.A. | Nutritional compositions including branched chain fatty acids and methods of using same |
| WO2014168925A1 (en) * | 2013-04-08 | 2014-10-16 | Virginia Commonwealth University | Compositions to alleviate presystemic metabolism of opioids |
| DE102013104441A1 (de) * | 2013-04-30 | 2014-10-16 | Bodo C. Melnik | Akne-Medikament und Verfahren zu seiner Herstellung |
| GB2528482A (en) * | 2014-07-23 | 2016-01-27 | Skintech Life Science Ltd | Pharmaceutical agent |
| JP7169591B2 (ja) * | 2016-09-15 | 2022-11-11 | スキンテック ライフ サイエンス リミテッド | 皮膚疾患の処置のためのｄｉｍの舌下又は頬側の投与 |
| US11241467B2 (en) | 2017-01-20 | 2022-02-08 | Skintech Life Science Limited | Composition for treating acne |
-
2018
- 2018-01-19 US US16/479,158 patent/US11241467B2/en active Active
- 2018-01-19 BR BR112019014942-2A patent/BR112019014942A2/pt not_active Application Discontinuation
- 2018-01-19 AU AU2018209393A patent/AU2018209393B2/en not_active Ceased
- 2018-01-19 EP EP18712449.0A patent/EP3570889A1/en not_active Withdrawn
- 2018-01-19 CN CN202310057791.0A patent/CN116036290A/zh active Pending
- 2018-01-19 WO PCT/IB2018/000109 patent/WO2018134683A1/en not_active Ceased
- 2018-01-19 JP JP2019537351A patent/JP7123058B2/ja active Active
- 2018-01-19 CN CN201880019777.9A patent/CN110446505A/zh active Pending
- 2018-01-19 CA CA3050208A patent/CA3050208A1/en active Pending
-
2021
- 2021-12-29 US US17/565,439 patent/US20220193167A1/en not_active Abandoned
-
2022
- 2022-08-09 JP JP2022127265A patent/JP7481402B2/ja active Active
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