JP2020505046A5 - - Google Patents

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Publication number
JP2020505046A5
JP2020505046A5 JP2019541082A JP2019541082A JP2020505046A5 JP 2020505046 A5 JP2020505046 A5 JP 2020505046A5 JP 2019541082 A JP2019541082 A JP 2019541082A JP 2019541082 A JP2019541082 A JP 2019541082A JP 2020505046 A5 JP2020505046 A5 JP 2020505046A5
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JP
Japan
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cancer
virus
promoter
seq
recombinant virus
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JP2019541082A
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English (en)
Japanese (ja)
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JP2020505046A (ja
JP7242534B2 (ja
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Priority claimed from PCT/US2018/016025 external-priority patent/WO2018140970A1/en
Publication of JP2020505046A publication Critical patent/JP2020505046A/ja
Publication of JP2020505046A5 publication Critical patent/JP2020505046A5/ja
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Publication of JP7242534B2 publication Critical patent/JP7242534B2/ja
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JP2019541082A 2017-01-30 2018-01-30 腫瘍選択的なtataボックスおよびcaatボックスの変異体 Active JP7242534B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762452075P 2017-01-30 2017-01-30
US62/452,075 2017-01-30
PCT/US2018/016025 WO2018140970A1 (en) 2017-01-30 2018-01-30 Tumor selective tata-box and caat-box mutants

Publications (3)

Publication Number Publication Date
JP2020505046A JP2020505046A (ja) 2020-02-20
JP2020505046A5 true JP2020505046A5 (https=) 2021-03-11
JP7242534B2 JP7242534B2 (ja) 2023-03-20

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ID=62978967

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019541082A Active JP7242534B2 (ja) 2017-01-30 2018-01-30 腫瘍選択的なtataボックスおよびcaatボックスの変異体

Country Status (14)

Country Link
US (2) US20190352669A1 (https=)
EP (1) EP3573632B1 (https=)
JP (1) JP7242534B2 (https=)
KR (2) KR102880548B1 (https=)
CN (1) CN110741081B (https=)
AU (1) AU2018212017B2 (https=)
BR (1) BR112019015514A2 (https=)
CA (1) CA3052086A1 (https=)
EA (1) EA201991806A1 (https=)
IL (1) IL268289B2 (https=)
MX (1) MX2019008922A (https=)
SG (1) SG11201906976YA (https=)
WO (1) WO2018140970A1 (https=)
ZA (1) ZA201905070B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
KR102608590B1 (ko) 2014-09-24 2023-12-01 솔크 인스티튜트 포 바이올로지칼 스터디즈 종양 살상 바이러스 및 이의 사용방법
WO2017147269A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3532082A4 (en) 2016-12-12 2020-08-26 Salk Institute for Biological Studies SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES
JP7229173B2 (ja) 2017-04-10 2023-02-27 エピセントアールエックス,インコーポレイテッド 組み換えウイルスを産生するための方法
CN112292449A (zh) 2018-04-09 2021-01-29 萨克生物研究学院 具有增强的复制特性的溶瘤腺病毒组合物
WO2024015876A1 (en) 2022-07-13 2024-01-18 Epicentrx, Inc. Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1190901A (en) * 1999-09-30 2001-04-30 Trustees Of The University Of Pennsylvania, The Replication selective adenoviruses for use in cancer therapy
WO2002082904A2 (en) * 2001-04-13 2002-10-24 The Trustees Of The University Of Pennsylvania Method of treating or retarding the development of blindness
CN1597939A (zh) * 2001-11-15 2005-03-23 杭州中肽生化有限公司 多功能抗癌重组腺病毒
CN101319215B (zh) * 2008-07-01 2010-12-22 郑骏年 人肿瘤特异性Ki67基因启动子
FI20090030A0 (fi) * 2009-02-02 2009-02-02 Akseli Eetu Hemminki Onkolyyttiset virukset
HUE026386T2 (en) * 2009-03-02 2016-06-28 Univ California Tumor-selective adenovirus e1a and e1b mutants
KR101427200B1 (ko) * 2011-11-24 2014-08-07 주식회사 바이로메드 아데노바이러스 생산 신규 세포주 및 그의 용도
FI123955B (en) * 2011-11-25 2014-01-15 Oncos Therapeutics Ltd Oncolytic adenovirus
US20140350087A9 (en) * 2012-03-22 2014-11-27 Halozyme, Inc. Oncovector Nucleic Acid Molecules and Methods of Use
RU2696312C2 (ru) * 2014-07-16 2019-08-01 Трансген Са Онколитический вирус для экспрессии модуляторов иммунологических контрольных точек
JP7216668B2 (ja) * 2017-05-26 2023-02-01 エピセントアールエックス,インコーポレイテッド 導入遺伝子を保持する組換えアデノウイルス

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