MX2019008922A - Mutantes de la caja tata y de la caja caat selectivas de tumor. - Google Patents

Mutantes de la caja tata y de la caja caat selectivas de tumor.

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Publication number
MX2019008922A
MX2019008922A MX2019008922A MX2019008922A MX2019008922A MX 2019008922 A MX2019008922 A MX 2019008922A MX 2019008922 A MX2019008922 A MX 2019008922A MX 2019008922 A MX2019008922 A MX 2019008922A MX 2019008922 A MX2019008922 A MX 2019008922A
Authority
MX
Mexico
Prior art keywords
box
caat
mutants
tumor
selective
Prior art date
Application number
MX2019008922A
Other languages
English (en)
Spanish (es)
Inventor
T Oronsky Bryan
Larson Christopher
R Reid Tony
Hedjran Farah
Original Assignee
Epicentrx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epicentrx Inc filed Critical Epicentrx Inc
Publication of MX2019008922A publication Critical patent/MX2019008922A/es

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    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10321Viruses as such, e.g. new isolates, mutants or their genomic sequences
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10332Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
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MX2019008922A 2017-01-30 2018-01-30 Mutantes de la caja tata y de la caja caat selectivas de tumor. MX2019008922A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762452075P 2017-01-30 2017-01-30
PCT/US2018/016025 WO2018140970A1 (en) 2017-01-30 2018-01-30 Tumor selective tata-box and caat-box mutants

Publications (1)

Publication Number Publication Date
MX2019008922A true MX2019008922A (es) 2020-01-20

Family

ID=62978967

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019008922A MX2019008922A (es) 2017-01-30 2018-01-30 Mutantes de la caja tata y de la caja caat selectivas de tumor.

Country Status (14)

Country Link
US (2) US20190352669A1 (https=)
EP (1) EP3573632B1 (https=)
JP (1) JP7242534B2 (https=)
KR (2) KR102880548B1 (https=)
CN (1) CN110741081B (https=)
AU (1) AU2018212017B2 (https=)
BR (1) BR112019015514A2 (https=)
CA (1) CA3052086A1 (https=)
EA (1) EA201991806A1 (https=)
IL (1) IL268289B2 (https=)
MX (1) MX2019008922A (https=)
SG (1) SG11201906976YA (https=)
WO (1) WO2018140970A1 (https=)
ZA (1) ZA201905070B (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201507393TA (en) 2013-03-14 2015-10-29 Salk Inst For Biological Studi Oncolytic adenovirus compositions
KR102608590B1 (ko) 2014-09-24 2023-12-01 솔크 인스티튜트 포 바이올로지칼 스터디즈 종양 살상 바이러스 및 이의 사용방법
WO2017147269A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
WO2017147265A1 (en) 2016-02-23 2017-08-31 Salk Institute For Biological Studies High throughput assay for measuring adenovirus replication kinetics
EP3532082A4 (en) 2016-12-12 2020-08-26 Salk Institute for Biological Studies SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES
JP7229173B2 (ja) 2017-04-10 2023-02-27 エピセントアールエックス,インコーポレイテッド 組み換えウイルスを産生するための方法
CN112292449A (zh) 2018-04-09 2021-01-29 萨克生物研究学院 具有增强的复制特性的溶瘤腺病毒组合物
WO2024015876A1 (en) 2022-07-13 2024-01-18 Epicentrx, Inc. Adenoviral vectors encapsulated in cationic liposomes, and preparation and use thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1190901A (en) * 1999-09-30 2001-04-30 Trustees Of The University Of Pennsylvania, The Replication selective adenoviruses for use in cancer therapy
WO2002082904A2 (en) * 2001-04-13 2002-10-24 The Trustees Of The University Of Pennsylvania Method of treating or retarding the development of blindness
CN1597939A (zh) * 2001-11-15 2005-03-23 杭州中肽生化有限公司 多功能抗癌重组腺病毒
CN101319215B (zh) * 2008-07-01 2010-12-22 郑骏年 人肿瘤特异性Ki67基因启动子
FI20090030A0 (fi) * 2009-02-02 2009-02-02 Akseli Eetu Hemminki Onkolyyttiset virukset
HUE026386T2 (en) * 2009-03-02 2016-06-28 Univ California Tumor-selective adenovirus e1a and e1b mutants
KR101427200B1 (ko) * 2011-11-24 2014-08-07 주식회사 바이로메드 아데노바이러스 생산 신규 세포주 및 그의 용도
FI123955B (en) * 2011-11-25 2014-01-15 Oncos Therapeutics Ltd Oncolytic adenovirus
US20140350087A9 (en) * 2012-03-22 2014-11-27 Halozyme, Inc. Oncovector Nucleic Acid Molecules and Methods of Use
RU2696312C2 (ru) * 2014-07-16 2019-08-01 Трансген Са Онколитический вирус для экспрессии модуляторов иммунологических контрольных точек
JP7216668B2 (ja) * 2017-05-26 2023-02-01 エピセントアールエックス,インコーポレイテッド 導入遺伝子を保持する組換えアデノウイルス

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Publication number Publication date
CN110741081A (zh) 2020-01-31
KR102880548B1 (ko) 2025-11-05
CA3052086A1 (en) 2018-08-02
AU2018212017B2 (en) 2024-11-28
EP3573632A1 (en) 2019-12-04
EP3573632A4 (en) 2020-09-23
IL268289B2 (en) 2025-09-01
US20190352669A1 (en) 2019-11-21
US20250388930A1 (en) 2025-12-25
SG11201906976YA (en) 2019-08-27
EP3573632B1 (en) 2024-08-07
BR112019015514A2 (pt) 2020-04-07
IL268289B1 (en) 2025-05-01
CN110741081B (zh) 2024-07-23
EP3573632C0 (en) 2024-08-07
WO2018140970A1 (en) 2018-08-02
EA201991806A1 (ru) 2020-02-13
JP2020505046A (ja) 2020-02-20
JP7242534B2 (ja) 2023-03-20
KR20230164231A (ko) 2023-12-01
KR102607220B1 (ko) 2023-12-01
ZA201905070B (en) 2024-12-18
KR20190128633A (ko) 2019-11-18
IL268289A (en) 2019-09-26
AU2018212017A1 (en) 2019-08-15

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