JP2020503267A5 - - Google Patents
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- Publication number
- JP2020503267A5 JP2020503267A5 JP2019528129A JP2019528129A JP2020503267A5 JP 2020503267 A5 JP2020503267 A5 JP 2020503267A5 JP 2019528129 A JP2019528129 A JP 2019528129A JP 2019528129 A JP2019528129 A JP 2019528129A JP 2020503267 A5 JP2020503267 A5 JP 2020503267A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- inhibitor
- composition according
- alkyl
- linear
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 239000003112 inhibitor Substances 0.000 claims 9
- 102000004890 Interleukin-8 Human genes 0.000 claims 7
- 108090001007 Interleukin-8 Proteins 0.000 claims 7
- 150000001875 compounds Chemical class 0.000 claims 5
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 4
- 125000005843 halogen group Chemical group 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 239000001257 hydrogen Substances 0.000 claims 3
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 claims 2
- 102100036166 C-X-C chemokine receptor type 1 Human genes 0.000 claims 2
- 101000947174 Homo sapiens C-X-C chemokine receptor type 1 Proteins 0.000 claims 2
- 208000000450 Pelvic Pain Diseases 0.000 claims 2
- 208000004403 Prostatic Hyperplasia Diseases 0.000 claims 2
- 208000013507 chronic prostatitis Diseases 0.000 claims 2
- 239000013256 coordination polymer Substances 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 235000019260 propionic acid Nutrition 0.000 claims 2
- 201000007094 prostatitis Diseases 0.000 claims 2
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 159000000000 sodium salts Chemical class 0.000 claims 2
- 239000002677 5-alpha reductase inhibitor Substances 0.000 claims 1
- 102100028989 C-X-C chemokine receptor type 2 Human genes 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- 108010018951 Interleukin-8B Receptors Proteins 0.000 claims 1
- 239000002160 alpha blocker Substances 0.000 claims 1
- 229940124308 alpha-adrenoreceptor antagonist Drugs 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 150000003384 small molecules Chemical group 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17150176.0 | 2017-01-03 | ||
| EP17150176.0A EP3342407A1 (en) | 2017-01-03 | 2017-01-03 | Il-8 inihibitors for use in the treatment of some urological disorders |
| PCT/EP2018/050009 WO2018127469A1 (en) | 2017-01-03 | 2018-01-02 | Il-8 inihibitors for use in the treatment of some urological disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020503267A JP2020503267A (ja) | 2020-01-30 |
| JP2020503267A5 true JP2020503267A5 (https=) | 2021-02-04 |
Family
ID=57758480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019528129A Withdrawn JP2020503267A (ja) | 2017-01-03 | 2018-01-02 | 特定の泌尿器系障害の治療における使用のためのｉｌ−８阻害剤 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20190336484A1 (https=) |
| EP (2) | EP3342407A1 (https=) |
| JP (1) | JP2020503267A (https=) |
| KR (1) | KR20190102177A (https=) |
| CN (1) | CN109937037A (https=) |
| AU (1) | AU2018206134A1 (https=) |
| BR (1) | BR112019009588A2 (https=) |
| CA (1) | CA3046531A1 (https=) |
| EA (1) | EA201991357A1 (https=) |
| IL (1) | IL267577A (https=) |
| MA (1) | MA47199A (https=) |
| MX (1) | MX2019007972A (https=) |
| WO (1) | WO2018127469A1 (https=) |
| ZA (1) | ZA201902427B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3868368A1 (en) * | 2020-02-21 | 2021-08-25 | Dompe' Farmaceutici S.P.A. | Cxcl8 (interleukin-8) activity inhibitor and corticosteroid combination and pharmaceutical composition and use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1212051A4 (en) * | 1999-08-27 | 2004-03-31 | Merck & Co Inc | METHOD FOR TREATING OR PREVENTING CHEMICAL PROSTATITIS OR CHRONIC POOL PAIN |
| PL1776336T3 (pl) | 2004-03-23 | 2010-06-30 | Dompe Farm Spa | Pochodne kwasu 2-fenylopropionowego i zawierające je kompozycje farmaceutyczne |
| EP2166006A1 (en) | 2008-09-18 | 2010-03-24 | Dompe' S.P.A. | 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them |
| WO2010078403A2 (en) | 2008-12-30 | 2010-07-08 | Lipella Pharmaceuticals Inc. | Methods and compositions for diagnosing urological disorders |
| US20120076791A1 (en) * | 2010-09-29 | 2012-03-29 | Philip Bosch | Methods Of Treating Chronic Prostatitis/Chronic Pelvic Pain Syndrome |
| CN105582134A (zh) * | 2014-09-12 | 2016-05-18 | 青岛华之草医药科技有限公司 | 一种治疗前列腺炎的中药组合物 |
| EP3117835A1 (en) * | 2015-07-14 | 2017-01-18 | Dompé farmaceutici s.p.a. | Il-8 inhibitors for use in the treatment of certain urological disorders |
-
2017
- 2017-01-03 EP EP17150176.0A patent/EP3342407A1/en not_active Withdrawn
-
2018
- 2018-01-02 WO PCT/EP2018/050009 patent/WO2018127469A1/en not_active Ceased
- 2018-01-02 EP EP18701088.9A patent/EP3565545A1/en not_active Withdrawn
- 2018-01-02 MX MX2019007972A patent/MX2019007972A/es unknown
- 2018-01-02 CA CA3046531A patent/CA3046531A1/en not_active Abandoned
- 2018-01-02 MA MA047199A patent/MA47199A/fr unknown
- 2018-01-02 KR KR1020197013259A patent/KR20190102177A/ko not_active Ceased
- 2018-01-02 CN CN201880003982.6A patent/CN109937037A/zh active Pending
- 2018-01-02 BR BR112019009588A patent/BR112019009588A2/pt not_active Application Discontinuation
- 2018-01-02 JP JP2019528129A patent/JP2020503267A/ja not_active Withdrawn
- 2018-01-02 US US16/475,166 patent/US20190336484A1/en not_active Abandoned
- 2018-01-02 EA EA201991357A patent/EA201991357A1/ru unknown
- 2018-01-02 AU AU2018206134A patent/AU2018206134A1/en not_active Abandoned
-
2019
- 2019-04-16 ZA ZA2019/02427A patent/ZA201902427B/en unknown
- 2019-06-23 IL IL267577A patent/IL267577A/en unknown
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