JP2020500909A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020500909A5 JP2020500909A5 JP2019530790A JP2019530790A JP2020500909A5 JP 2020500909 A5 JP2020500909 A5 JP 2020500909A5 JP 2019530790 A JP2019530790 A JP 2019530790A JP 2019530790 A JP2019530790 A JP 2019530790A JP 2020500909 A5 JP2020500909 A5 JP 2020500909A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- heteroaryl
- heterocyclyl
- alkynyl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022070763A JP2022090051A (ja) | 2016-12-07 | 2022-04-22 | ＰＩ３Ｋδ阻害剤としてのイミダゾ［１，５－ａ］ピラジン誘導体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2016/108897 | 2016-12-07 | ||
| CN2016108897 | 2016-12-07 | ||
| PCT/CN2017/114970 WO2018103688A1 (en) | 2016-12-07 | 2017-12-07 | IMIDAZO [1,5-A] PYRAZINE DERIVATIVES AS PI3Kdelta INHIBITORS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022070763A Division JP2022090051A (ja) | 2016-12-07 | 2022-04-22 | ＰＩ３Ｋδ阻害剤としてのイミダゾ［１，５－ａ］ピラジン誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020500909A JP2020500909A (ja) | 2020-01-16 |
| JP2020500909A5 true JP2020500909A5 (enExample) | 2021-01-21 |
| JP7064495B2 JP7064495B2 (ja) | 2022-05-10 |
Family
ID=62491736
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019530790A Expired - Fee Related JP7064495B2 (ja) | 2016-12-07 | 2017-12-07 | ＰＩ３Ｋδ阻害剤としてのイミダゾ［１，５－ａ］ピラジン誘導体 |
| JP2022070763A Pending JP2022090051A (ja) | 2016-12-07 | 2022-04-22 | ＰＩ３Ｋδ阻害剤としてのイミダゾ［１，５－ａ］ピラジン誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022070763A Pending JP2022090051A (ja) | 2016-12-07 | 2022-04-22 | ＰＩ３Ｋδ阻害剤としてのイミダゾ［１，５－ａ］ピラジン誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11136323B2 (enExample) |
| EP (1) | EP3551630A4 (enExample) |
| JP (2) | JP7064495B2 (enExample) |
| KR (1) | KR20190091339A (enExample) |
| CN (2) | CN114805366A (enExample) |
| AU (2) | AU2017372377B2 (enExample) |
| BR (1) | BR112019011847A2 (enExample) |
| CA (1) | CA3045959A1 (enExample) |
| EA (1) | EA201991355A1 (enExample) |
| IL (2) | IL266986B (enExample) |
| MX (1) | MX394882B (enExample) |
| NZ (1) | NZ754944A (enExample) |
| SG (1) | SG10201912192RA (enExample) |
| TW (2) | TWI762534B (enExample) |
| WO (1) | WO2018103688A1 (enExample) |
| ZA (1) | ZA201903286B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3551630A4 (en) | 2016-12-07 | 2020-07-15 | Beigene, Ltd. | IMIDAZO [1,5-A] PYRAZINE DERIVATIVES AS PI3KDELTA INHIBITORS |
| IL272988B (en) | 2017-09-08 | 2022-08-01 | Beigene Ltd | Imidazo-[1,5-a]pyrazine derivatives as pi3k-delta inhibitors |
| US20230011916A1 (en) * | 2019-11-21 | 2023-01-12 | Beigene, Ltd. | Methods of cancer treatment using anti-ox40 antibodies in combination with pi3 kinase delta inhibitors |
| KR102344185B1 (ko) * | 2020-02-26 | 2021-12-27 | 계명대학교 산학협력단 | 신규한 Pim 키나아제 억제제 및 이의 용도 |
| IL308856A (en) * | 2021-05-27 | 2024-01-01 | Beigene Switzerland Gmbh | SALTS OF A PI3Kdelta INHIBITOR, CRYSTALLINE FORMS, METHODS OF PREPARATION, AND USES THEREFORE |
| JP2024535799A (ja) * | 2021-09-14 | 2024-10-02 | ベイジーン スウィッツァーランド ゲーエムベーハー | Ｂｔｋ阻害剤及びｐｉ３キナーゼ阻害剤の組み合わせを使用したがん治療の方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2372694T3 (es) | 2003-10-15 | 2012-01-25 | OSI Pharmaceuticals, LLC | Inhibidores de tirosina cinasa de imidazo[1,5-a]pirazina. |
| NZ596185A (en) | 2009-04-16 | 2013-01-25 | Ct Nac Investigaciones Oncologicas Cnio | Imidazopyrazines for use as kinase inhibitors |
| RU2013138835A (ru) | 2011-02-09 | 2015-03-20 | Ф. Хоффманн-Ля Рош Аг | Гетероциклические соединения в качестве ингибиторов pi3 киназы |
| WO2013104610A1 (en) * | 2012-01-10 | 2013-07-18 | Bayer Intellectual Property Gmbh | Substituted imidazopyrazines as akt kinase inhibitors |
| KR102229478B1 (ko) | 2012-11-01 | 2021-03-18 | 인피니티 파마슈티칼스, 인코포레이티드 | Pi3 키나아제 동형단백질 조절인자를 사용하는 암의 치료 |
| ES2834638T3 (es) * | 2013-05-30 | 2021-06-18 | Infinity Pharmaceuticals Inc | Tratamiento de cánceres usando moduladores de isoforma de PI3 cinasa |
| CA2922058A1 (en) * | 2013-10-18 | 2015-04-23 | Medivation Technologies, Inc. | Heterocyclic compounds and methods of use |
| RS62713B1 (sr) | 2014-08-11 | 2022-01-31 | Acerta Pharma Bv | Terapeutske kombinacije btk inhibitora i bcl-2 inhibitora |
| EP3551630A4 (en) * | 2016-12-07 | 2020-07-15 | Beigene, Ltd. | IMIDAZO [1,5-A] PYRAZINE DERIVATIVES AS PI3KDELTA INHIBITORS |
| IL272988B (en) | 2017-09-08 | 2022-08-01 | Beigene Ltd | Imidazo-[1,5-a]pyrazine derivatives as pi3k-delta inhibitors |
-
2017
- 2017-12-07 EP EP17877406.3A patent/EP3551630A4/en not_active Withdrawn
- 2017-12-07 US US16/466,621 patent/US11136323B2/en active Active
- 2017-12-07 TW TW106143023A patent/TWI762534B/zh not_active IP Right Cessation
- 2017-12-07 EA EA201991355A patent/EA201991355A1/ru unknown
- 2017-12-07 TW TW111114434A patent/TW202233190A/zh unknown
- 2017-12-07 CA CA3045959A patent/CA3045959A1/en active Pending
- 2017-12-07 BR BR112019011847-0A patent/BR112019011847A2/pt not_active IP Right Cessation
- 2017-12-07 NZ NZ754944A patent/NZ754944A/en not_active IP Right Cessation
- 2017-12-07 CN CN202210507333.8A patent/CN114805366A/zh active Pending
- 2017-12-07 WO PCT/CN2017/114970 patent/WO2018103688A1/en not_active Ceased
- 2017-12-07 SG SG10201912192RA patent/SG10201912192RA/en unknown
- 2017-12-07 AU AU2017372377A patent/AU2017372377B2/en not_active Ceased
- 2017-12-07 MX MX2019006612A patent/MX394882B/es unknown
- 2017-12-07 CN CN201780076039.3A patent/CN110267959B/zh not_active Expired - Fee Related
- 2017-12-07 JP JP2019530790A patent/JP7064495B2/ja not_active Expired - Fee Related
- 2017-12-07 KR KR1020197019710A patent/KR20190091339A/ko not_active Ceased
-
2019
- 2019-05-24 ZA ZA2019/03286A patent/ZA201903286B/en unknown
- 2019-05-29 IL IL266986A patent/IL266986B/en unknown
-
2021
- 2021-07-08 US US17/370,728 patent/US11725012B2/en active Active
-
2022
- 2022-02-07 IL IL290419A patent/IL290419B2/en unknown
- 2022-04-22 JP JP2022070763A patent/JP2022090051A/ja active Pending
- 2022-05-31 AU AU2022203737A patent/AU2022203737A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020534259A5 (enExample) | ||
| JP2014514317A5 (enExample) | ||
| MX2021009763A (es) | Derivados de 3-(1-oxo-5-(piperidin-4-il)isoindolin-2-il)piperidina -2,6-diona y usos de los mismos. | |
| HRP20230400T1 (hr) | Benzilamino supstituirani piridopirimidinoni i derivati kao inhibitori sos1 | |
| JP2018516917A5 (enExample) | ||
| ES2855732T3 (es) | Compuestos y composiciones para tratar afecciones asociadas con la actividad de NLRP | |
| JP2015531773A5 (enExample) | ||
| JP2018507877A5 (enExample) | ||
| JP2017509586A5 (enExample) | ||
| JP2018511587A5 (enExample) | ||
| CN110582489A (zh) | Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途 | |
| JP2016503779A5 (enExample) | ||
| NZ721617A (en) | Heterocyclic compounds | |
| HRP20171453T1 (hr) | Derivati imidazotiadiazola i imidazopirazina kao inhibitori proteazom aktiviranog receptora 4 (par4) za liječenje agregacije trombocita | |
| JP2018529739A5 (enExample) | ||
| HRP20201469T1 (hr) | Derivati tetrahidroizokinolina | |
| JP2017500338A5 (enExample) | ||
| JP2016513660A5 (enExample) | ||
| JP2016525075A5 (enExample) | ||
| MX2016011992A (es) | Derivados de piperidina-diona. | |
| HRP20211392T1 (hr) | INHIBITOR EGFR -a, I NJEGOVA PRIPREMA I PRIMJENA | |
| RU2016102036A (ru) | Производное хинолина | |
| JP2013523802A5 (enExample) | ||
| JP2017530185A5 (enExample) | ||
| EA201401063A1 (ru) | Алкил 2-{[(2r,3s,5r)-5-(4-амино-2-оксо-2h-пиримидин-1-ил)-3-гидрокситетрагидрофуран-2-илметокси]феноксифосфориламино}пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения |