JP2020094070A - Skin external preparation - Google Patents

Abstract

To provide a skin external preparation that contains a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer surfactant, and an oil-soluble ultraviolet absorber, and has enhanced ultraviolet protection effect and improved preparation stability.SOLUTION: A skin external preparation contains a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer surfactant, and an oil-soluble ultraviolet absorber.SELECTED DRAWING: Figure 1

Description

The present invention relates to a skin external preparation containing a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer type surfactant, and an oil-soluble UV absorber, which has a high UV protection effect and good formulation stability.

Although the external skin preparation is required to have a good feeling in use, it has been demanded to enhance not only the feeling in use but also the ultraviolet protection effect in view of the recent high awareness of whitening. In order to improve the feeling of use, a silicone elastomer known as a texture improver is used. By making a water-in-oil emulsion containing two types of emulsifying silicone elastomers, it has a highly viscous texture and has excellent texture on the skin. A composition having a good feeling in use, which is spread in the above, is disclosed (Patent Document 1). In addition, in order to enhance the UV protection effect, by combining an oil agent, a triazine-based UV absorber, and a rheology control agent such as a silicone elastomer, formulation stability is good and studies have been conducted to improve the UV protection effect. (Patent Document 2).

Japanese Patent Laid-Open No. 2007-16029 Japanese Patent Laid-Open No. 2011-121947

However, with the compositions described in Patent Document 1 and Patent Document 2, the ultraviolet protection effect is not sufficiently enhanced, and phase separation or liquid discharge may occur over time, and the usability is not satisfactory. It was Further, in the composition described in Patent Document 2, stability may be a problem such as precipitation of a triazine-based ultraviolet absorber.

Therefore, the present invention enhances the excellent ultraviolet protection effect by containing a dimethicone crosspolymer having no emulsifying effect and an alkyl-modified silicone crosspolymer, and further containing a silicone elastomer type surfactant and an oil-soluble ultraviolet absorber, The external preparation for skin has a good preparation stability and a good feeling in use.

That is, the gist of the present invention is as follows.
Item 1. A skin external preparation containing a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer type surfactant, and an oil-soluble ultraviolet absorber.
Item 2. Item 2. The external skin preparation according to Item 1, which contains the alkyl-modified silicone crosspolymer in a proportion of 0.01 to 100 parts by weight with respect to 1 part by weight of dimethicone crosspolymer.
Item 3. Item 3. The external skin preparation according to Item 1 or 2, containing 1 to 15% by weight of the dimethicone crosspolymer.
Item 4. Item 4. The external preparation for skin according to any one of Items 1 to 3, containing 0.1 to 8% by weight of the alkyl-modified silicone crosspolymer.
Item 5. Item 5. The external preparation for skin according to any one of Items 1 to 4, which is substantially anhydrous.
Item 6. Furthermore, the external preparation for skin according to any one of Items 1 to 5, which contains a metal powder.
Item 7. A method for enhancing ultraviolet protection, which comprises a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer type surfactant, and an oil-soluble ultraviolet absorber.
Item 8. A method for improving formulation stability, which comprises a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer-type surfactant, and an oil-soluble ultraviolet absorber.
Item 9. A skin external preparation for covering the skin, comprising a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer type surfactant, and an oil-soluble ultraviolet absorber.
Item 10. A moisturizing skin external preparation comprising a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer type surfactant, and an oil-soluble ultraviolet absorber.

The external preparation for skin of the present invention has an enhanced UV protection effect, has good formulation stability over time, and has a good feeling during use.

FIG. 3 is a view showing the ultraviolet ray protective effect of the external preparations for skin of Example 1, Comparative Example 1 and Comparative Example 2. FIG. 3 is a view showing the results of measuring viscoelasticity of the external preparation for skin of Example 1. FIG. 5 is a view showing the results of viscoelasticity measurement of the external preparation for skin of Comparative Example 1. FIG. 7 is a view showing the results of viscoelasticity measurement of the external preparation for skin of Comparative Example 2.

The present invention relates to a skin external preparation containing a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer type surfactant, and an oil-soluble ultraviolet absorber.

Dimethicone Crosspolymer Dimethicone crosspolymer is a paste or particles obtained by three-dimensionally cross-linking a siloxane skeleton. It has elastic feel unique to an elastic body and sebum absorbability due to being a cross-linked body, and does not have emulsifying ability. , Useful for obtaining a good feel of the formulation.

The dimethicone crosspolymer used in the present invention may have a particle shape or may have a shape of an oil dispersion without a shape, but it has a particle shape and is a silicone elastomer. It is preferable that the primary particle size of the powder is in the range of 0.1 to 50 μm and the shape of the primary particles is spherical. Further, it is preferable that the silicone elastomer having a particle shape is kneaded with an oil agent, finely pulverized by a pulverizer, or incorporated into the formulation in one or more forms selected from an aqueous dispersion. The surface of the silicone elastomer may or may not be surface-treated with a different type of silicone compound. The dimethicone crosspolymer used in the present invention is commercially available or can be produced by a known method.

As a specific example of the dimethicone crosspolymer used in the present invention, those provided as a mixture with an oil agent are preferable. Specifically, 9040 Silicone Elastomer Blend, 9045 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blen, 8041 Silicone Elastomer Blend, 8041 Silicone Elastomer Blend, 8041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 8041 Silicone Elastomer Blend, 8041 Silicone Elastomer Blend, 8041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 8041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 8041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, 8041 Examples include, but are not limited to, Emulsion, 9027 Silicone Elastomer Blend, 9041 Silicone Elastomer Blend, and 9546 Silicone Elastomer Blend. Among them, 9040 Silicone Elastomer Blend and 9045 Silicone Elastomer Blend are preferable. In the present invention, the dimethicone crosspolymer can be used alone or in combination of two or more.

The amount of the dimethicone crosspolymer to be blended is usually 0.1 to 20% by weight, preferably 0.1 to 15% by weight, based on 100% by weight of the skin external preparation, from the viewpoint of stability and usability. , And more preferably 1 to 11% by weight.

Alkyl-modified silicone crosspolymer Alkyl-modified silicone crosspolymer is a component that imparts a smooth and silky feel because it is a fine particle with a tertiary crosslink structure by adding an alkyl group to a three-dimensionally crosslinked siloxane skeleton. Is. Further, it is preferable that an alkyl-modified silicone crosspolymer having a particle shape is kneaded with an oil agent, finely pulverized by a pulverizer, or incorporated in a formulation in one or more forms selected from an aqueous dispersion.
The alkyl-modified silicone crosspolymer used in the invention is commercially available or can be prepared by known methods.

The alkyl-modified silicone crosspolymer used in the present invention is preferably an oil dispersion. As a specific example, Shin-Etsu Silicone Co., Ltd. (vinyl dimethicone/lauryl dimethicone) crosspolymer (trade name; KSG-41, KSG-42, KSG-43, KSG-44), (lauryl polydimethylsiloxyethyl dimethicone/bisvinyl) Dimethicone) Crosspolymer (trade name: KSG-042Z, KSG-045Z), (Cetearyl Dimethicone/Vinyl Dimethicone) crosspolymer (trade name: SILSOFT Silicone Gel), Cetearyl Dimethicone Crosspolymer manufactured by Momentive Performance Materials, Inc. (VELVESIL DM), alkyl (C30-45) cetearyl dimethicone crosspolymer (VELVESIL125, VELVESIL034), and the like, but are not limited thereto. Among them, (vinyl dimethicone/lauryl dimethicone) crosspolymer is preferable. In the present invention, the alkyl-modified silicone crosspolymer may be used alone or in combination of two or more.

The content of the alkyl-modified silicone crosspolymer in the external preparation for skin of the present invention is usually 0 in 100% by weight of the external preparation for skin from the viewpoints of dispersion stability, formulation stability, compatibility with ultraviolet absorbers, and stickiness. It is 0.001 to 20% by weight, preferably 0.01 to 10% by weight, and more preferably 0.1 to 8% by weight.

In the external preparation for skin of the present invention, the amount of the alkyl-modified silicone crosspolymer is 0.01 to 100 parts by weight, preferably 0.05 to 50 parts by weight, based on 1 part by weight of the dimethicone crosspolymer.

Silicone Elastomer-Type Surfactant In the present specification, the silicone elastomer-type surfactant is generally a derivative of a silicone elastomer in which polysiloxane is modified with a functional group such as an alkylene oxide group, and the surfactant (emulsifying agent) is used. Noh and the ability to disperse powder). The silicone elastomer type surfactant used in the present invention is commercially available or can be produced by a known method.

Specific examples of the silicone elastomer type surfactant used in the present invention include (lauryl dimethicone/polyglycerin-3) crosspolymer (trade name: KSG-810, KSG-820, KSG-830, KSG) manufactured by Shin-Etsu Silicone Co., Ltd. -840), (polyglyceryl-3/lauryl polydimethylsiloxyethyl dimethicone) crosspolymer (trade name: KSG-820Z, KSG-850Z), (dimethicone/polyglycerin-3) crosspolymer (trade name: KSG-710), (PEG-15/lauryl dimethicone) cross polymer (trade name: KSG-310, KSG-320, KSG-330, KSG-340), (PEG-15/lauryl polydimethylsiloxyethyl dimethicone) cross polymer (trade name: KSG -320Z, KSG-350Z, KSG-360Z) and the like, but are not limited thereto. Among them, (lauryl dimethicone/polyglycerin-3) crosspolymer is preferable. In the present invention, the silicone elastomer type surfactant may be used alone or in combination of two or more kinds.

From the viewpoint of formulation stability, the content of the silicone elastomer type surfactant used in the present invention is usually 0.01 to 10% by weight in 100% by weight of the composition for external use of the present invention, and preferably 0. It is 1 to 8% by weight, and more preferably 0.1 to 5% by weight.
Further, in the external preparation for skin of the present invention, the silicone elastomer type surfactant is blended in an amount of 0.0001 to 100 parts by weight, preferably 0.001 to 50 parts by weight, relative to 1 part by weight of dimethicone crosspolymer.

Oil-Soluble UV Absorber In the present specification, the oil-soluble UV absorber is a UV absorber that is not dissolved in water and has a UV protection effect. The oil-soluble ultraviolet absorber used in the present invention is commercially available or can be produced by a known method.

Specific examples used in the present invention include 2,4-bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1,3. ,5-Triazine, 2,4,6-tris[4-(2-ethylhexyloxycarbonyl)anilino]-1,3,5-triazine, 2-[4-(diethylamino)-2-hydroxybenzoyl]hexyl benzoate Examples include, but are not limited to, esters, 2-ethylhexyl paramethoxycinnamate, 4-tert-butyl-4′-methoxy-dibenzoylmethane, octocrylene, polysilicone-15, and the like. Among them, 2-ethylhexyl paramethoxycinnamate and polysilicone 15 are preferable. In the present invention, the oil-soluble ultraviolet absorber may be used alone or in combination of two or more.

The content of the oil-soluble ultraviolet absorber used in the present invention is usually 0.1 to 20% by weight in 100% by weight of the composition for external use of the present invention, from the viewpoints of ultraviolet protection effect, feeling of use, and formulation stability. %, preferably 0.1 to 10% by weight, more preferably 0.5 to 10% by weight, but not limited to this.

Further, 0.001 to 200 parts by weight, preferably 0.001 to 150 parts by weight of the oil-soluble ultraviolet absorber is blended with 1 part by weight of dimethicone crosspolymer.

Water Furthermore, the external preparation for skin of the present invention may be anhydrous and substantially free of water. The case of substantially not containing water means that the content of water is 1% by weight or less, and the content of a small amount of water due to addition of an extract or the like is substantially anhydrous.

Metal Powder Further, the external skin preparation of the present invention may contain a metal powder. In the present specification, the metal powder is a fine particle of a metal such as titanium oxide or zinc oxide, and preferably has a UV protection effect. The metal powder used in the present invention is commercially available or can be produced by a known method.

Specific examples used in the present invention include inorganic compounds such as zinc oxide, titanium oxide, iron oxide, cerium oxide, zirconium oxide, titanium silicate, zinc silicate, silicic anhydride, cerium silicate, and hydrous silicic acid. , These inorganic compounds coated with an inorganic powder such as hydrous silicic acid, aluminum hydroxide, mica, or talc, these inorganic compounds composite with resin powder such as polyamide, polyethylene, polyester, polystyrene, or nylon Examples thereof include, but are not limited to, those treated with or coated with silicone oil, fatty acid aluminum salt and the like. In the present invention, the metal powder may be used alone or in combination of two or more.

The content of the metal powder used in the present invention is usually 0.1 to 50% by weight in 100% by weight of the composition for external use of the present invention, from the viewpoints of ultraviolet protection effect, feeling of use, and formulation stability. It is preferably 0.1 to 30% by weight, more preferably 0.5 to 20% by weight.

Further, 0.001 to 200 parts by weight, preferably 0.001 to 150 parts by weight of the metal powder is blended with 1 part by weight of dimethicone crosspolymer.

The skin external preparation of the present invention contains the dimethicone crosspolymer described above, an alkyl-modified silicone crosspolymer, a silicone elastomer-type surfactant and an oil-soluble ultraviolet absorber, whereby the ultraviolet protection effect is enhanced and the formulation is stable. Sex is improved.
Furthermore, the composition for external use of the present invention has an excellent soft focus property in which stickiness and shine are suppressed, pores and fine wrinkles are hard to see, and the skin has a transparent feeling, and is excellent in the feeling of use and light in use. Is.

Other components The external composition of the present invention contains the dimethicone crosspolymer described above, an alkyl-modified silicone crosspolymer, a silicone elastomer-type surfactant and an oil-soluble ultraviolet absorber, and other various purposes. , Moisturizing component, polyhydric alcohol, scrubbing agent, ultraviolet absorbing component, anti-inflammatory agent, astringent component, vitamins, peptide or derivative thereof, amino acid or derivative thereof, cleaning component, antibacterial component, keratin softening component, cell activating component, Other components such as an antiaging component, a blood circulation promoting component, and a whitening component may be contained within a range that does not impair the effects of the present invention. In addition, these other components may be used individually by 1 type, or may be used in combination of 2 or more type.

Examples of the moisturizing component include diglycerin trehalose; high molecular compounds such as sodium hyaluronate, heparin analogues, sodium chondroitin sulfate, collagen, elastin, keratin, chitin and chitosan; amino acids such as glycine, aspartic acid and arginine; lactic acid Natural moisturizing factors such as sodium, urea and sodium pyrrolidonecarboxylate; lipids such as ceramide, cholesterol and phospholipid; plant extract extracts such as chamomile extract, hamamelis extract, tea extract and perilla extract.

The polyhydric alcohol preferably has 2 to 10 carbon atoms, and for example, glycerin, diglycerin, triglycerin, propylene glycol, dipropylene glycol, ethylene glycol, diethylene glycol, isoprene glycol, 1,3-butylene glycol, sorbitol. , Xylitol, erythritol, mannitol, pentanediol, hexanediol, octanediol, decanediol, neopentyl glycol and the like.

Among these, glycerin, diglycerin, triglycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, ethylene glycol, diethylene glycol, isoprene glycol, sorbitol, xylitol, erythritol, mannitol, pentanediol, hexanediol, octanediol. Are preferred, and glycerin, diglycerin, propylene glycol, dipropylene glycol, 1,3-butylene glycol, diethylene glycol, isoprene glycol, sorbitol, xylitol, erythritol, mannitol, pentanediol, and hexanediol are more preferred.

Examples of the scrubbing agent include apricot kernel powder, almond shell powder, apricot kernel powder, sodium chloride particles, olive kernel powder, seawater dried product particles, candelilla wax, walnut shell powder, cherry kernel powder, coral powder, charcoal powder. , Powdered hazelnut shells, polyethylene powder, silicic acid anhydride and the like.

Examples of the ultraviolet absorbing component include phenylbenzimidazole sulfonic acid, ferulic acid, sodium dihydroxydimethoxydibenzophenone disulfonate, hydroxymethoxybenzophenone sulfonic acid, sodium hydroxymethoxybenzophenone sulfonate, and the like.

Examples of the anti-inflammatory agent include glycyrrhetinic acid, glycyrrhizic acid derivative, azulene, components derived from plants (for example, comfrey), zinc oxide, tocopherol acetate, allantoin, aminocaproic acid and hydrocortisone.

Examples of the astringent component include zinc oxide, zinc sulfate, aluminum chloride, zinc sulfocarbonate and tannic acid.

Examples of the vitamins include vitamin Es such as dl-α-tocopherol, dl-α-tocopherol acetate, dl-α-tocopherol succinate, and dl-α-tocopherol succinate calcium; riboflavin, flavin mononucleotide, flavin adenine diamine. Vitamin B2s such as nucleotides, riboflavin butyrate, riboflavin tetrabutyrate, riboflavin 5'-phosphate sodium salt, riboflavin tetranicotinate; nicotinic acid, dl-α-tocopherol nicotinate, benzyl nicotinate, methyl nicotinate, Nicotinic acid such as β-butoxyethyl nicotinate, 1-(4-methylphenyl)ethyl nicotinate, and nicotinic acid amide; ascorbogen-A, ascorbyl stearate, ascorbyl palmitate, dipalmitate L-ascorbyl, etc. C vitamins; methyl hesperidin, ergocalciferol, cholecalciferol, and other vitamin Ds; phylloquinone, farnoquinone, and other vitamin Ks; γ-oryzanol, dibenzoylthiamine, dibenzoylthiamine hydrochloride; thiamine hydrochloride, thiaminecetyl Hydrochloride, thiamine thiocyanate, thiamine lauryl hydrochloride, thiamine nitrate, thiamine monophosphate, thiamine lysine salt, thiamine triphosphate, thiamine monophosphate ester, thiamin monophosphate ester, thiamine diphosphate ester, thiamine diline Vitamin B1s such as acid ester hydrochloride, thiamine triphosphate, thiamine triphosphate monophosphate; vitamin B6s such as pyridoxine hydrochloride, pyridoxine acetate, pyridoxal hydrochloride, 5'-phosphate pyridoxal hydrochloride, pyridoxamine hydrochloride; cyanocobalamin, hydroxo Vitamin B12s such as cobalamin and deoxyadenosylcobalamin; folic acids such as folic acid and pteroylglutamic acid; pantothenic acid, calcium pantothenate, pantothenyl alcohol (panthenol), D-pantethein, D-pantethine, coenzyme A, Pantothenic acids such as pantothenyl ethyl ether; Biotins such as biotin and biocytin; Vitamin C which is an ascorbic acid derivative such as ascorbic acid, sodium ascorbate, dehydroascorbic acid, sodium ascorbate phosphate, magnesium ascorbate phosphate Kinds; carnitine, ferulic acid, α-lipoic acid, orot Examples thereof include vitamin-like action factors such as acids.

As the peptide or its derivative, keratin-degrading peptide, hydrolyzed keratin, collagen, fish-derived collagen, atelocollagen, gelatin, elastin, elastin-degrading peptide, collagen-degrading peptide, hydrolyzed collagen, hydroxypropylammonium chloride hydrolyzed collagen, elastin-degrading Peptide, conchiolin degrading peptide, hydrolyzed conchiolin, silk proteolytic peptide, hydrolyzed silk, lauroyl hydrolyzed silk sodium, soybean proteolytic peptide, hydrolyzed soybean protein, wheat protein, wheat proteolytic peptide, hydrolyzed wheat protein, casein degradation Examples thereof include peptides and acylated peptides (palmitoyl oligopeptide, palmitoyl pentapeptide, palmitoyl tetrapeptide, etc.).

As the amino acid or a derivative thereof, betaine (trimethylglycine), proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, β-alanine, threonine, glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, Methionine, leucine, isoleucine, valine, histidine, taurine, γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid, carnitine, carnosine, creatine and the like can be mentioned.

As the cleaning component, soaps selected from alkali metal salts such as potassium laurate, potassium myristate, potassium palmitate or potassium stearate, alkanolamide salts or amino acid salts; cocoyl glutamate Na, cocoyl methyl taurine Na, etc. Amino acid surfactants; ether sulfate salts such as Na laureth sulfate; ether carboxylates such as Na lauryl ether acetate; sulfosuccinate salts such as alkyl sulfosuccinate Na; coconut oil fatty acid monoethanolamide, coconut oil fatty acid diethanolami Fatty acid alkanolamides such as sodium lauryl phosphate, sodium polyoxyethylene lauryl ether phosphate, and other monoalkyl phosphate ester salts; coconut oil fatty acid amide propyldimethylaminoacetic acid betaine, lauryldimethylaminoacetic acid betaine, 2-alkyl-N -Betaine-type amphoteric surfactants such as carboxymethyl-N-hydroxyethyl imidazolinium betaine, lauryl hydroxysulfobetaine and lauroylamidoethyl hydroxyethyl carboxymethyl betaine hydroxypropyl sodium phosphate; amino acid type amphoteric amphoteric such as sodium lauryl aminopropionate Examples thereof include surfactants.

Examples of the antibacterial component include chlorhexidine, salicylic acid, benzalkonium chloride, acrinol, ethanol, benzethonium chloride, cresol, gluconic acid and its derivatives, povidone iodine, potassium iodide, iodine, isopropylmethylphenol, triclocarban, triclosan, and photosensitizer 101. No. 1, Photosensitizer No. 201, paraben, phenoxyethanol, 1,2-pentanediol, alkyldiaminoglycine hydrochloride, pyroctoolamine, miconazole and the like.

Examples of the keratin softening component include lactic acid, salicylic acid, glycolic acid salicylate, gluconic acid, citric acid, malic acid, fruit acid, phytic acid, urea and sulfur.

Examples of the cell-activating component include amino acids such as γ-aminobutyric acid and ε-aminocaproic acid; vitamins such as retinol, thiamine, riboflavin, pyridoxine hydrochloride and pantothenic acids; α-hydroxy acids such as glycolic acid and lactic acid; tannin. , Flavonoid, saponin, and Photosensitizer No. 301.

Examples of the antiaging component include pangamamic acid, kinetin, ursolic acid, turmeric extract, sphingosine derivative, silicon, silicic acid, N-methyl-L-serine, mevalonolactone and the like.

Examples of the blood circulation promoting component include plants (for example, Panax ginseng, ashitaba, arnica, ginkgo, fennel, ginkgo, Dutch oak, chamomile, Roman chamomile, carrot, gentian, burdock, rice, hawthorn, shiitake mushroom, ginger, hawthorn, hazelnut. , Senkyu, senburi, thyme, clove, chimp, chili pepper, touki, tounin, spruce, carrot, garlic, butcher bloom, grapes, buttons, marronnier, melissa, yuzu, yokinin, ryokcha, rosemary, rosehip, chinpi, touki, Components derived from spruce, peach, apricots, walnuts, corn); acetylcholine, ictamol, cantharisin tincture, gamma-oryzanol, cepharanthin, trazoline, tocopherol nicotinate, glucosyl hesperidin, and the like.

The whitening ingredients include tocopherol, ascorbic acid and/or salts thereof, tranexamic acid, ascorbic acid derivatives, arbutin, 4-alkylresorcinol and/or salts thereof, 4-methoxysalicylic acid, hydroquinone, kojic acid. , A placenta extract and the like, and a plant component having a whitening effect (for example, an extract of psyllium, Yukinoshita, aloe, etc.) and the like.

Sunscreen composition The external preparation for skin of the present invention can be used as a sunscreen composition. The sunscreen composition can be suitably used as an external preparation for protection of skin and hair from ultraviolet rays, prevention of sunburn, and the like. The amount and usage of the sunscreen composition of the present invention applied to the skin are not particularly limited, and usually, an appropriate amount can be applied to the skin or the like several times a day, for example, applied. It can also have a function as a makeup base.

Foundation composition The external preparation for skin of the present invention can be used as a foundation composition. The foundation composition can be used as a skin external preparation for covering skin spots, freckles, fine wrinkles, pores and downy hair, evenly adjusting the skin color, and making the skin look beautiful. The amount and usage of the foundation composition of the present invention applied to the skin are not particularly limited, and usually, an appropriate amount can be applied to the skin several times a day, for example, applied. It can also have a function as a makeup base.

Method for producing external preparation for skin The method for producing external preparation for skin of the present invention is not particularly limited, and includes dimethicone crosspolymer which is an essential component, an alkyl-modified silicone crosspolymer, a silicone elastomer type surfactant and an oil-soluble ultraviolet absorber. In addition, various components (the above-mentioned other components, water, etc.) necessary for producing an ordinary external preparation for skin can be appropriately selected and blended and produced by a conventional method.

Formulation form
Examples of the dosage form of the external preparation for skin of the present invention include pharmaceuticals, quasi drugs and cosmetics.In this case, the essential components and other components described above are used as pharmaceuticals, quasi drugs or cosmetics. These formulations may be mixed with a commonly used base or carrier and, if necessary, additives to be described later according to a conventional method.

The external preparation for skin may be either an Si/O type emulsion or an O/Si type emulsion, and the emulsion may further contain water. For example, depending on the feeling of use and the performance to be imparted, these You can choose which one to use.

Further, the form of the external preparation for skin of the above quasi drug or cosmetic preparation is not particularly limited, and examples thereof include basic cosmetics such as lotion, emulsion, cream, beauty essence, pack, hand cream, body lotion, and body cream. Cosmetics for cleaning such as face wash, makeup remover, body shampoo; makeup cosmetics such as foundation, makeup base, lip balm, lipstick, blush, and bath salts. These preparations can be manufactured according to a conventional method.

Further, as the above-mentioned base or carrier, oils and fats such as coconut oil, olive oil, rice bran oil and shea butter; hydrocarbons such as petrolatum and liquid paraffin; waxes such as jojoba oil, miuro, candelilla wax and lanolin; cetanol , Higher alcohols such as cetostearyl alcohol, stearyl alcohol, behenyl alcohol, octyldodecanol, isostearyl alcohol, phytosterol and cholesterol; silicones such as dimethicone, cyclic silicones and modified silicones; celluloses such as ethyl cellulose, hydroxypropyl cellulose and hydroxypropyl methyl cellulose Derivatives; polyvinylpyrrolidone; carrageenan; polyvinyl butyrate; polyethylene glycol; dioxane; butylene glycol adipic acid polyester; diisopropyl adipate, isopropyl myristate, octyldodecyl myristate, isopropyl palmitate, cetyl palmitate, isononyl isononanoate, tetra-2- Esters such as pentahexyl ethylhexanoate; polysaccharides such as dextrin and maltodextrin; vinyl-based polymers such as carboxyvinyl polymer and alkyl-modified carboxyvinyl polymer; lower alcohols such as ethanol and isopropanol; and diethylene glycol monoethyl ether Glycol ether; water and the like can be mentioned. When the sunscreen composition of the present invention comprises a polyhydric alcohol, the polyhydric alcohol may also serve as a base or carrier.

The above-mentioned bases or carriers can be used alone or in combination of two or more, and the amount thereof is appropriately selected from the range known to those skilled in the art.

Additives The topical composition for external use of the present invention contains known additives, such as surfactants, stabilizers, and antioxidants, which are added to pharmaceuticals, quasi drugs or cosmetics, as long as the effects of the present invention are not impaired. , A colorant, a pearly luster imparting agent, a dispersant, a chelating agent, a pH adjusting agent, a preservative, a thickener, an irritation reducing agent, and a fragrance can be added. These additives may be used alone or in combination of two or more.

Examples of the surfactant include sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monostearate, penta-2-ethylhexyl diglycerol sorbitan, and tetra-2-ethylhexyl diglycerol sorbitan. Sorbitan fatty acid esters; propylene glycol fatty acid esters such as propylene glycol monostearate; polyoxyethylene hydrogenated castor oil 40 (HCO-40), polyoxyethylene hydrogenated castor oil 50 (HCO-50), polyoxyethylene hydrogenated castor Oil 60 (HCO-60), hydrogenated castor oil derivatives such as polyoxyethylene hydrogenated castor oil 80; polyoxyethylene (20) sorbitan monolaurate (polysorbate 20), polyoxyethylene (20) sorbitan monostearate (polysorbate 60) ), polyoxyethylene (20) sorbitan monooleate (polysorbate 80), polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene (20) sorbitan isostearate; polyoxyethylene monococonut oil fatty acid glyceryl; glycerin alkyl ether; alkyl Glucosides; polyoxyalkylene alkyl ethers such as polyoxyethylene cetyl ether; amines such as stearylamine and oleylamine.

Examples of the stabilizer include sodium polyacrylate, dibutylhydroxytoluene, butylhydroxyanisole and the like.

Examples of the antioxidant include dibutylhydroxytoluene, butylhydroxyanisole, sorbic acid, sodium sulfite, ascorbic acid, erythorbic acid, and L-cysteine hydrochloride.

Examples of the colorant include inorganic pigments and natural pigments.

Examples of the pearlescent agent include ethylene glycol distearate, ethylene glycol monostearate, and triethylene glycol distearate.

Examples of the dispersant include sodium pyrophosphate, sodium hexametaphosphate, polyvinyl alcohol, polyvinylpyrrolidone, methyl vinyl ether/maleic anhydride cross-linked copolymer, organic acid and the like.

Examples of the chelating agent include EDTA.disodium salt and citric acid.

Examples of the pH adjuster include inorganic acids (hydrochloric acid, sulfuric acid, etc.), organic acids (lactic acid, sodium lactate, citric acid, sodium citrate, succinic acid, sodium succinate, etc.), inorganic bases (potassium hydroxide, water). Sodium oxide) and organic bases (triethanolamine, diisopropanolamine, triisopropanolamine, etc.) and the like.

Examples of the preservatives include benzoic acid, sodium benzoate, dehydroacetic acid, sodium dehydroacetate, parabens and phenoxyethanol.

Examples of the thickeners include cellulosic thickeners such as methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxymethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, carboxymethylcellulose and carboxyethylcellulose, guar gum, pectin, pullulan, gelatin, locust bean. Gum, carrageenan, agar, xanthan gum, polyvinyl alcohol, polyvinylpyrrolidone, carboxyvinyl polymer, acrylic acid alkyl methacrylate copolymer, polyethylene glycol, bentonite, alginic acid, propylene glycol alginate, macrogol, sodium chondroitin sulfate, hyaluronic acid, hyaluronic acid Sodium, (hydroxyethyl acrylate/acryloyl dimethyl taurine Na) copolymer, (acryloyl dimethyl taurine ammonium/vinyl pyrrolidone) copolymer and the like can be mentioned.

Examples of the irritation reducing agent include licorice extract, sodium alginate, gum arabic, polyvinylpyrrolidone, licorice extract, sodium alginate and the like.

Hereinafter, the present invention will be described in more detail with reference to Examples, but the present invention is not limited thereto.

Test example 1
Preparation of Test Formulation The components shown in Table 1 were uniformly mixed at room temperature, and then these were stirred with a homomixer to be sufficiently homogeneously mixed to obtain a target formulation. The test was carried out using the obtained test formulation.

UV protection effect test
Each external preparation for skin shown in Table 1 was uniformly applied to a plate made of polymethylmethacrylate so as to have a concentration of 1.3 mg/cm ² , and naturally dried, and then the ultraviolet absorption spectrum was measured by an ultraviolet spectrophotometer (Japan It was measured using a spectrophotometer, V-650).
The results are shown in Figure 1. The skin external preparation of Example 1 of the present application is a skin external preparation of Comparative Example 1 containing a silicone type surfactant which is not an elastomer type instead of the silicone elastomer type surfactant and Comparative Example 2 containing a sorbitan type surfactant. In comparison, a high ultraviolet absorption effect was exhibited in a wide wavelength range covering UVA waves (about 320 to 400 nm) and UVB waves (about 280 to 320 nm).

Test example 2
The test was carried out using the same test preparation as in Test Example 1.

Formulation stability test
Each skin external preparation shown in Table 1 was measured for viscoelasticity by using a Bolin viscometer (product number: MCR302: Anton Pearl Japan Co.) to observe formulation stability. It is known that the long-term dispersion stability of a formulation sample can be evaluated by measuring viscoelasticity. , It can be predicted that the formulation will maintain stability for a long period of time (COSMETIC STAGE Vol. 6 No. 6 2012). About 5 g of each external preparation for skin shown in Table 1 was placed, a jig was installed, and then excess preparation was removed, and measurement conditions (temperature control method: plate type Peltier temperature control system, angular frequency: 0.1 to 10 Hz) , Strain amount: 0.12%, measurement temperature 25° C., measurement jig: cone plate type, 40 mm, cone angle 4° C.).
The results are shown in Figure 2. In Example 1, the storage elastic modulus curve and the loss elastic modulus curve are parallel without intersecting each other, but in Comparative Example 1 and Comparative Example 2, two curves intersect with each other, and the skin external preparation of Example 1 has formulation stability. However, in Comparative Examples 1 and 2, the formulation stability was poor.

Test example 3
The test was performed using Example 1 of Test Example 1 and Comparative Example 1.

Usability test For the two preparations of Example 1 and Comparative Example 1, three in-house monitors compared the usability and evaluated the moist feeling and the feeling of skin coverage.
In all three persons, Example 1 had a moist feeling and a result that a skin covering feeling was obtained.

According to a conventional method, each component was uniformly mixed to obtain a skin external preparation. All of them had high ultraviolet absorption ability, excellent stability, and good usability.

Claims (7)

A skin external preparation containing a dimethicone crosspolymer, an alkyl-modified silicone crosspolymer, a silicone elastomer-type surfactant, and an oil-soluble ultraviolet absorber and being substantially anhydrous. The external preparation for skin according to claim 1, which contains the dimethicone crosspolymer in an amount of 1 to 15% by weight. The external preparation for skin according to claim 1, which contains 0.1 to 8% by weight of the alkyl-modified silicone crosspolymer. The external preparation for skin according to any one of claims 1 to 3, which contains 0.01 to 100 parts by weight of the alkyl-modified silicone crosspolymer with respect to 1 part by weight of the dimethicone crosspolymer. The external preparation for skin according to any one of claims 1 to 4, further comprising a metal powder. The external preparation for skin according to claim 5, which contains 0.001 to 200 parts by weight of the metal powder with respect to 1 part by weight of the dimethicone crosspolymer. The above-mentioned silicone elastomer type surfactants are (lauryl dimethicone/polyglycerin-3) crosspolymer, (polyglyceryl-3/lauryl polydimethylsiloxyethyl dimethicone) crosspolymer, (dimethicone/polyglycerin-3) crosspolymer, (PEG -15/lauryl dimethicone) crosspolymer, and (PEG-15/lauryl polydimethylsiloxyethyl dimethicone) crosspolymer, at least one selected from the group consisting of the external preparations for skin according to any one of claims 1 to 6. ..