JP2020019769A5 - - Google Patents

Download PDF

Info

Publication number
JP2020019769A5
JP2020019769A5 JP2019142108A JP2019142108A JP2020019769A5 JP 2020019769 A5 JP2020019769 A5 JP 2020019769A5 JP 2019142108 A JP2019142108 A JP 2019142108A JP 2019142108 A JP2019142108 A JP 2019142108A JP 2020019769 A5 JP2020019769 A5 JP 2020019769A5
Authority
JP
Japan
Prior art keywords
stage
dose
antibody
pharmaceutical composition
interval
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2019142108A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020019769A (ja
JP6672516B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2020019769A publication Critical patent/JP2020019769A/ja
Publication of JP2020019769A5 publication Critical patent/JP2020019769A5/ja
Application granted granted Critical
Publication of JP6672516B2 publication Critical patent/JP6672516B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2019142108A 2018-08-01 2019-08-01 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法 Active JP6672516B2 (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201862713211P 2018-08-01 2018-08-01
US62/713,211 2018-08-01
US201862764952P 2018-08-17 2018-08-17
US62/764,952 2018-08-17
US201862760204P 2018-11-13 2018-11-13
US62/760,204 2018-11-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020025071A Division JP6672533B1 (ja) 2018-08-01 2020-02-18 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法

Publications (3)

Publication Number Publication Date
JP2020019769A JP2020019769A (ja) 2020-02-06
JP2020019769A5 true JP2020019769A5 (https=) 2020-03-19
JP6672516B2 JP6672516B2 (ja) 2020-03-25

Family

ID=67660420

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2019142108A Active JP6672516B2 (ja) 2018-08-01 2019-08-01 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法
JP2020025071A Active JP6672533B1 (ja) 2018-08-01 2020-02-18 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法
JP2020036818A Pending JP2020079331A (ja) 2018-08-01 2020-03-04 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法
JP2025018896A Pending JP2025065367A (ja) 2018-08-01 2025-02-07 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2020025071A Active JP6672533B1 (ja) 2018-08-01 2020-02-18 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法
JP2020036818A Pending JP2020079331A (ja) 2018-08-01 2020-03-04 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法
JP2025018896A Pending JP2025065367A (ja) 2018-08-01 2025-02-07 C5関連疾患の治療または予防用の医薬組成物およびc5関連疾患を治療または予防するための方法

Country Status (23)

Country Link
US (1) US20210301004A1 (https=)
EP (2) EP3829628B1 (https=)
JP (4) JP6672516B2 (https=)
KR (5) KR20210037743A (https=)
CN (1) CN112512563A (https=)
AU (2) AU2019315213B2 (https=)
BR (1) BR112021001655A2 (https=)
CA (1) CA3107618A1 (https=)
CR (1) CR20210103A (https=)
DE (1) DE112019003835T5 (https=)
ES (1) ES2980137T3 (https=)
HR (1) HRP20240823T1 (https=)
HU (1) HUE067057T2 (https=)
IL (2) IL280475B2 (https=)
MX (2) MX2021000516A (https=)
MY (1) MY210523A (https=)
PH (1) PH12021550226A1 (https=)
PL (1) PL3829628T3 (https=)
RS (1) RS65630B1 (https=)
SG (1) SG10202002898RA (https=)
SM (1) SMT202400271T1 (https=)
TW (2) TWI701041B (https=)
WO (1) WO2020027279A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104761637B (zh) 2006-03-31 2021-10-15 中外制药株式会社 调控抗体血液动力学的方法
ES2595638T3 (es) 2007-09-26 2017-01-02 Chugai Seiyaku Kabushiki Kaisha Método para modificar el punto isoeléctrico de un anticuerpo mediante la sustitución de aminoácidos en una CDR
KR102057826B1 (ko) 2008-04-11 2019-12-20 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복 결합하는 항원 결합 분자
EP2647706B1 (en) 2010-11-30 2023-05-17 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
KR101860280B1 (ko) 2014-12-19 2018-05-21 추가이 세이야쿠 가부시키가이샤 항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
BR112017011235A2 (pt) 2014-12-19 2018-02-06 Chugai Pharmaceutical Co Ltd anticorpos anti-c5 e métodos de uso
KR102605798B1 (ko) 2015-02-05 2023-11-23 추가이 세이야쿠 가부시키가이샤 이온 농도 의존적 항원 결합 도메인을 포함하는 항체, Fc 영역 개변체, IL-8에 결합하는 항체, 및 그들의 사용
WO2017110981A1 (en) 2015-12-25 2017-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
EP3494991A4 (en) 2016-08-05 2020-07-29 Chugai Seiyaku Kabushiki Kaisha COMPOSITION FOR THE PROPHYLAXIS OR TREATMENT OF IL-8 RELATED DISEASES

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
JP3101690B2 (ja) 1987-03-18 2000-10-23 エス・ビィ・2・インコーポレイテッド 変性抗体の、または変性抗体に関する改良
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
US6074642A (en) 1994-05-02 2000-06-13 Alexion Pharmaceuticals, Inc. Use of antibodies specific to human complement component C5 for the treatment of glomerulonephritis
US6194551B1 (en) 1998-04-02 2001-02-27 Genentech, Inc. Polypeptide variants
ATE375365T1 (de) 1998-04-02 2007-10-15 Genentech Inc Antikörper varianten und fragmente davon
PL209392B1 (pl) 1999-01-15 2011-08-31 Genentech Inc Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała
US6737056B1 (en) 1999-01-15 2004-05-18 Genentech, Inc. Polypeptide variants with altered effector function
EP2896631A1 (en) 2000-10-10 2015-07-22 Genentech, Inc. Inhibition of complement C5 activation for the treatment and prevention of delayed xenograft or acute vascular rejection
ES2283594T5 (es) 2001-08-17 2016-03-15 Genentech, Inc. Inhibidores de la ruta del complemento que se unen a C5 y C5a sin impedir la formación de C5b
ITMI20021527A1 (it) 2002-07-11 2004-01-12 Consiglio Nazionale Ricerche Anticorpi anti componente c5 del complemento e loro uso
US7361740B2 (en) 2002-10-15 2008-04-22 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
TWI335821B (en) 2002-12-16 2011-01-11 Genentech Inc Immunoglobulin variants and uses thereof
US20050169921A1 (en) 2004-02-03 2005-08-04 Leonard Bell Method of treating hemolytic disease
US20070116710A1 (en) 2004-02-03 2007-05-24 Leonard Bell Methods of treating hemolytic anemia
PT1737891E (pt) 2004-04-13 2013-04-16 Hoffmann La Roche Anticorpos anti p-selectina
TWI380996B (zh) 2004-09-17 2013-01-01 Hoffmann La Roche 抗ox40l抗體
US20090220508A1 (en) 2006-03-15 2009-09-03 Alexion Pharmaceuticals, Inc. Treatment Of Paroxysmal Nocturnal Hemoglobinuria Patients By An Inhibitor Of Complement
KR102057826B1 (ko) 2008-04-11 2019-12-20 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복 결합하는 항원 결합 분자
PY09026846A (es) 2008-08-05 2015-09-01 Novartis Ag Composiciones y métodos para anticuerpos que se dirigen a la proteína de complemento c5
CA2742802C (en) 2008-11-10 2019-11-26 Alexion Pharmaceuticals, Inc. Methods and compositions for treating complement-associated disorders
JP5932670B2 (ja) 2010-03-11 2016-06-08 ライナット ニューロサイエンス コーポレイション pH依存性の抗原結合を有する抗体
TWI667257B (zh) 2010-03-30 2019-08-01 中外製藥股份有限公司 促進抗原消失之具有經修飾的FcRn親和力之抗體
WO2014119969A1 (ko) * 2013-01-31 2014-08-07 서울대학교 산학협력단 보체 관련 질환의 예방 및 치료를 위한 c5 항체 및 방법
BR112017011235A2 (pt) * 2014-12-19 2018-02-06 Chugai Pharmaceutical Co Ltd anticorpos anti-c5 e métodos de uso
CA2972393A1 (en) * 2015-02-27 2016-09-01 Chugai Seiyaku Kabushiki Kaisha Composition for treating il-6-related diseases
EP3402816A1 (en) 2016-01-11 2018-11-21 Alexion Pharmaceuticals, Inc. Dosage and administration of anti-c5 antibodies for treatment
WO2017132259A1 (en) 2016-01-25 2017-08-03 Shire Human Genetic Therapies, Inc. Anti-c5 antibodies with enhanced ph switch
CN118512588A (zh) * 2017-10-26 2024-08-20 亚力兄制药公司 用于治疗阵发性夜间性血红蛋白尿(pnh)和非典型溶血性尿毒症综合征(ahus)的抗c5抗体的剂量和施用
CN111683672A (zh) * 2017-12-04 2020-09-18 Ra制药公司 补体活性调节剂

Similar Documents

Publication Publication Date Title
JP2020019769A5 (https=)
HRP20240823T1 (hr) Farmaceutski pripravak, namijenjen upotrebi u liječenju ili sprječavanju bolesti povezane s c5 i postupak liječenja ili sprječavanja bolesti povezane s c5
Kohn et al. Anti-tumour necrosis factor alpha (infliximab) in the treatment of severe ulcerative colitis: result of an open study on 13 patients
JP2013533858A5 (https=)
JP2025004195A5 (https=)
JP2017523187A5 (https=)
JP2018522851A5 (https=)
CN109985237B (zh) 一种治疗结直肠癌的药物组合物及其应用
JP2022532356A5 (https=)
JP2022504468A5 (https=)
JP2022501332A5 (https=)
US20210346319A1 (en) Pharmaceutical Compositions of R-(+)-Propranolol in Enantiomeric Excess and Therapeutic Uses Related Thereto
Marik et al. Delayed hypersensitivity reaction to vancomycin
JP2023545084A5 (https=)
CN108939074B (zh) 治疗再生障碍性贫血的方法和药物组合物
Weiner et al. Mogamulizumab Multimodality Therapy with Systemic Retinoids, Interferon, or Extracorporeal Photopheresis for Advanced Cutaneous T‐Cell Lymphoma
NO344366B1 (no) Anvendelse av et radiomerket anti-CD20-antistoff for fremstilling av et medikament for behandling av en pasient med B-celle-lymfom.
CN119326902A (zh) 癌症联合治疗的组合物与方法
JP2022104920A5 (https=)
Girish et al. Infliximab treatment in refractory Kawasaki syndrome
CN121511095A (zh) 治疗表达cd20的b细胞癌症的方法
JP2020531480A5 (https=)
JP2024515879A5 (https=)
Vahdat et al. Rapidly cycled courses of high-dose alkylating agents supported by filgrastim and peripheral blood progenitor cells in patients with metastatic breast cancer.
RU2021104477A (ru) Фармацевтическая композиция, предназначенная для применения для лечения или предупреждения связанного с с5 заболевания, и способ лечения или предупреждения связанного с с5 заболевания