|
US5594001A
(en)
|
1993-04-08 |
1997-01-14 |
The Dupont Merck Pharmaceutical Company |
Polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders
|
|
US5654307A
(en)
|
1994-01-25 |
1997-08-05 |
Warner-Lambert Company |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
|
|
IL112248A0
(en)
*
|
1994-01-25 |
1995-03-30 |
Warner Lambert Co |
Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
|
|
US20020168761A1
(en)
|
2000-01-24 |
2002-11-14 |
Gour Barbara J. |
Peptidomimetic modulators of cell adhesion
|
|
US6608053B2
(en)
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
JP2004511435A
(ja)
|
2000-07-27 |
2004-04-15 |
ファルマシア・コーポレーション |
うっ血性心不全の処置のための、エポキシ−ステロイド型アルドステロン拮抗薬とβ−アドレナリン作動性拮抗薬の併用療法
|
|
US7291733B2
(en)
|
2003-10-10 |
2007-11-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Substituted tricyclic heterocycles and their uses
|
|
ES2344007T3
(es)
|
2003-10-14 |
2010-08-16 |
The Arizona Board Of Regents On Behalf Of The University Of Arizona |
Inhibidores proteina quinasa.
|
|
US20090099165A1
(en)
|
2003-10-14 |
2009-04-16 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Protein Kinase Inhibitors
|
|
AR049300A1
(es)
|
2004-06-15 |
2006-07-12 |
Schering Corp |
Compuestos triciclicos antagonistas de mglur1 como agentes terapeuticos
|
|
EP1773840B1
(de)
|
2004-07-23 |
2010-01-20 |
The Medicines Company (Leipzig) GmbH |
Substituierte pyrido[3',2':4,5]thieno[3,2-d]pyrimidine und pyrido[3',2':4,5]furo[3,2-d]-pyrimidine zur verwendung als inhibitoren der pda-4 und/oder tnf-alpha freisetzung
|
|
EP1619196A1
(de)
|
2004-07-23 |
2006-01-25 |
Curacyte Discovery GmbH |
Substituierte Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine und Pyrido[3',2':4,5]furo[3,2-d]-pyrimidine zur Verwendung als Inhibitoren der PDA-4 und/oder TNF-alpha Freisetzung
|
|
CA2583550C
(en)
|
2004-10-25 |
2013-05-14 |
Eli Lily And Company |
Thienopyridines as allosteric potentiators of the m4 muscarinic receptor
|
|
ES2259892B1
(es)
|
2004-11-30 |
2007-11-01 |
Laboratorios Almirall S.A. |
Nuevos derivados de piridotienopirimidina.
|
|
ES2259891B1
(es)
|
2004-11-30 |
2007-11-01 |
Laboratorios Almirall S.A. |
Nuevos derivados de piridotienopirimidina.
|
|
WO2006138418A2
(en)
|
2005-06-14 |
2006-12-28 |
President And Fellows Of Harvard College |
Improvement of cognitive performance with sirtuin activators
|
|
AR059901A1
(es)
|
2006-03-20 |
2008-05-07 |
Bayer Pharmaceuticals Corp |
Compuestos de tetrahidropiridotienopirimidina utiles para tratar o prevenir trastornos proliferativos celulares.
|
|
WO2007146284A2
(en)
*
|
2006-06-12 |
2007-12-21 |
Vertex Pharmaceuticals Incorporated |
Thienopyrimidines useful as modulators of ion channels
|
|
US8153803B2
(en)
*
|
2006-07-18 |
2012-04-10 |
The General Hospital Corporation |
Compositions and methods for modulating sirtuin activity
|
|
US20080021063A1
(en)
|
2006-07-18 |
2008-01-24 |
Kazantsev Aleksey G |
Compositions and methods for modulating sirtuin activity
|
|
US7547781B2
(en)
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
|
JP2010514810A
(ja)
|
2006-12-29 |
2010-05-06 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
Ａｘｌインヒビターとして有用な置換トリアゾール
|
|
US20090105240A1
(en)
|
2007-10-17 |
2009-04-23 |
Tomas Mustelin |
Methods for treating leukemia and myelodysplastic syndrome, and methods for identifying agents for treating same
|
|
US20100009934A1
(en)
|
2008-06-09 |
2010-01-14 |
Combinatorx, Incorporated |
Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders
|
|
JP5746172B2
(ja)
|
2009-08-20 |
2015-07-08 |
カルス セラピューティクス リミテッド |
ホスホイノシチド３−キナーゼ阻害剤としての三環式複素環化合物
|
|
US20110178107A1
(en)
|
2010-01-20 |
2011-07-21 |
Taigen Biotechnology Co., Ltd. |
Hcv protease inhibitors
|
|
WO2012131297A1
(en)
|
2011-03-28 |
2012-10-04 |
Jonathan Bayldon Baell |
Pyrido [3',2' :4,5] thieno [3, 2-d] pyrimidin- 4 - ylamine derivatives and their therapeutical use
|
|
US9056876B2
(en)
|
2011-09-16 |
2015-06-16 |
Vanderbilt University |
Substituted 1H-pyrazolo[3′,4′,4,5]thieno[2,3-b]pyridin-3-amine analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
|
|
US20130116241A1
(en)
|
2011-11-09 |
2013-05-09 |
Abbvie Inc. |
Novel inhibitor compounds of phosphodiesterase type 10a
|
|
JP6473330B2
(ja)
|
2011-12-21 |
2019-02-20 |
ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド，ア ボディ コーポレイト |
ＲａｌＧＴＰアーゼを標的とする抗がん化合物及びその使用方法
|
|
US8697888B2
(en)
|
2012-01-06 |
2014-04-15 |
Vanderbilt University |
Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M1 receptors
|
|
ES2656972T3
(es)
|
2012-02-23 |
2018-03-01 |
Vanderbilt University |
Análogos de 5-aminotieno [2,3-c] piridazin-6-carboxamida como moduladores alostéricos positivos del receptor de acetilcolina muscarínico M4
|
|
EP2872144A4
(en)
|
2012-07-11 |
2015-12-02 |
Nimbus Iris Inc |
IRAQ INHIBITOR AND USES THEREOF
|
|
US9056875B2
(en)
|
2012-08-31 |
2015-06-16 |
Vanderbilt University |
Substituted pyrazolo[3′,4′:4,5]thieno[2,3-C]pyridazin-3-amine analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
|
|
US20160200733A1
(en)
|
2013-08-23 |
2016-07-14 |
Vanderbilt University |
Substituted thieno[2,3-b]pyridine-2-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m4
|
|
WO2015027214A1
(en)
|
2013-08-23 |
2015-02-26 |
Vanderbilt University |
Substituted thieno[2,3-c]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m4
|
|
WO2015200619A1
(en)
|
2014-06-26 |
2015-12-30 |
Rodin Therapeutics, Inc. |
Inhibitors of histone deacetylase
|
|
FI3474846T3
(fi)
|
2016-06-22 |
2023-02-16 |
Univ Vanderbilt |
Muskariinisen asetyylikoliinireseptorin m4 positiiviset allosteeriset modulaattorit
|
|
EP3534901B1
(en)
|
2016-11-07 |
2022-06-22 |
Vanderbilt University |
Positive allosteric modulators of the muscarinic acetylcholine receptor m4
|
|
CN109863139B
(zh)
|
2016-11-07 |
2023-02-17 |
范德比尔特大学 |
毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
|