|
US5594001A
(en)
|
1993-04-08 |
1997-01-14 |
The Dupont Merck Pharmaceutical Company |
Polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders
|
|
CA2160112A1
(en)
*
|
1993-04-08 |
1994-10-27 |
Christopher Allan Teleha |
Novel polycyclic systems, and derivatives thereof, as neurotransmitter release enhancers useful in the treatment of cognitive disorders
|
|
US5654307A
(en)
|
1994-01-25 |
1997-08-05 |
Warner-Lambert Company |
Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family
|
|
IL112248A0
(en)
|
1994-01-25 |
1995-03-30 |
Warner Lambert Co |
Tricyclic heteroaromatic compounds and pharmaceutical compositions containing them
|
|
US20020168761A1
(en)
|
2000-01-24 |
2002-11-14 |
Gour Barbara J. |
Peptidomimetic modulators of cell adhesion
|
|
US6608053B2
(en)
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
|
ATE330633T1
(de)
|
2000-07-27 |
2006-07-15 |
Pharmacia Corp |
Epoxy-steroidaler aldosteronantagonist und beta- adrenergischer antagonist-kombinationstherapie zur behandlung von kongestivem herzversagen
|
|
US7291733B2
(en)
|
2003-10-10 |
2007-11-06 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Substituted tricyclic heterocycles and their uses
|
|
US20090099165A1
(en)
|
2003-10-14 |
2009-04-16 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Protein Kinase Inhibitors
|
|
CA2542076C
(en)
|
2003-10-14 |
2013-02-26 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Substituted tricyclic compounds as protein kinase inhibitors
|
|
PE20060526A1
(es)
|
2004-06-15 |
2006-07-13 |
Schering Corp |
Compuestos triciclicos como antagonistas de mglur1
|
|
EP1619196A1
(de)
|
2004-07-23 |
2006-01-25 |
Curacyte Discovery GmbH |
Substituierte Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine und Pyrido[3',2':4,5]furo[3,2-d]-pyrimidine zur Verwendung als Inhibitoren der PDA-4 und/oder TNF-alpha Freisetzung
|
|
WO2006010567A1
(de)
|
2004-07-23 |
2006-02-02 |
Curacyte Discovery Gmbh |
INHIBITOREN DER PHOSPHODIESTERASE 4 UND TNFα-FREISETZUNG
|
|
MX2007004794A
(es)
*
|
2004-10-25 |
2007-07-09 |
Lilly Co Eli |
Tienopiridinas como potenciadores alostericos del receptor muscarinico m4.
|
|
ES2259892B1
(es)
|
2004-11-30 |
2007-11-01 |
Laboratorios Almirall S.A. |
Nuevos derivados de piridotienopirimidina.
|
|
ES2259891B1
(es)
|
2004-11-30 |
2007-11-01 |
Laboratorios Almirall S.A. |
Nuevos derivados de piridotienopirimidina.
|
|
PL1828199T3
(pl)
*
|
2004-12-17 |
2009-10-30 |
Hoffmann La Roche |
Pochodne tieno-pirydyny jako alosteryczne wzmacniacze gaba-b
|
|
WO2006138418A2
(en)
|
2005-06-14 |
2006-12-28 |
President And Fellows Of Harvard College |
Improvement of cognitive performance with sirtuin activators
|
|
AR059901A1
(es)
|
2006-03-20 |
2008-05-07 |
Bayer Pharmaceuticals Corp |
Compuestos de tetrahidropiridotienopirimidina utiles para tratar o prevenir trastornos proliferativos celulares.
|
|
US7745449B2
(en)
*
|
2006-04-21 |
2010-06-29 |
Amgen Inc. |
Thieno-[2,3-d]pyrimidine and thieno-pyridazine compounds and methods of use
|
|
US20080021063A1
(en)
|
2006-07-18 |
2008-01-24 |
Kazantsev Aleksey G |
Compositions and methods for modulating sirtuin activity
|
|
US7547781B2
(en)
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
|
EP2079736B1
(en)
|
2006-12-29 |
2017-10-18 |
Rigel Pharmaceuticals, Inc. |
Substituted triazoles useful as axl inhibitors
|
|
US20090105240A1
(en)
|
2007-10-17 |
2009-04-23 |
Tomas Mustelin |
Methods for treating leukemia and myelodysplastic syndrome, and methods for identifying agents for treating same
|
|
US20100009934A1
(en)
|
2008-06-09 |
2010-01-14 |
Combinatorx, Incorporated |
Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders
|
|
ES2534326T3
(es)
|
2009-08-20 |
2015-04-21 |
Karus Therapeutics Limited |
Compuestos tricíclicos heterocíclicos como inhibidores de la fosfoinositida 3-cinasa
|
|
US20110178107A1
(en)
|
2010-01-20 |
2011-07-21 |
Taigen Biotechnology Co., Ltd. |
Hcv protease inhibitors
|
|
WO2012131297A1
(en)
*
|
2011-03-28 |
2012-10-04 |
Jonathan Bayldon Baell |
Pyrido [3',2' :4,5] thieno [3, 2-d] pyrimidin- 4 - ylamine derivatives and their therapeutical use
|
|
WO2013040534A1
(en)
|
2011-09-16 |
2013-03-21 |
Vanderbilt University |
Substituted 1h-pyrazolo[3',4',4,5]thieno[2,3-b]pyridin-3-amine analogs as positive allosteric modulatiors of the muscarinic acetycholine receptor m4
|
|
US20130116241A1
(en)
|
2011-11-09 |
2013-05-09 |
Abbvie Inc. |
Novel inhibitor compounds of phosphodiesterase type 10a
|
|
CN104271132B
(zh)
|
2011-12-21 |
2018-01-12 |
科罗拉多大学董事会法人团体 |
靶向Ral GTP酶的抗癌化合物及使用其的方法
|
|
US8697888B2
(en)
|
2012-01-06 |
2014-04-15 |
Vanderbilt University |
Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M1 receptors
|
|
WO2013126856A1
(en)
|
2012-02-23 |
2013-08-29 |
Vanderbilt University |
Substituted 5-aminothieno[2,3-c]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m4
|
|
HK1210696A1
(en)
|
2012-07-11 |
2016-05-06 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
US9056875B2
(en)
|
2012-08-31 |
2015-06-16 |
Vanderbilt University |
Substituted pyrazolo[3′,4′:4,5]thieno[2,3-C]pyridazin-3-amine analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
|
|
US20160200733A1
(en)
*
|
2013-08-23 |
2016-07-14 |
Vanderbilt University |
Substituted thieno[2,3-b]pyridine-2-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m4
|
|
WO2015027214A1
(en)
|
2013-08-23 |
2015-02-26 |
Vanderbilt University |
Substituted thieno[2,3-c]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor m4
|
|
US9981920B2
(en)
|
2014-06-26 |
2018-05-29 |
Rodin Therapeutics, Inc. |
Inhibitors of histone deacetylase
|
|
ES2936827T3
(es)
*
|
2016-06-22 |
2023-03-22 |
Univ Vanderbilt |
Moduladores alostéricos positivos del receptor muscarínico de acetilcolina M4
|
|
WO2018085808A1
(en)
|
2016-11-07 |
2018-05-11 |
Vanderbilt University |
Positive allosteric modulators of the muscarinic acetylcholine receptor m4
|
|
CN109890388B
(zh)
|
2016-11-07 |
2023-03-28 |
范德比尔特大学 |
毒蕈碱型乙酰胆碱受体m4的正向别构调节剂
|