JP2019537438A5 - - Google Patents
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- JP2019537438A5 JP2019537438A5 JP2019522850A JP2019522850A JP2019537438A5 JP 2019537438 A5 JP2019537438 A5 JP 2019537438A5 JP 2019522850 A JP2019522850 A JP 2019522850A JP 2019522850 A JP2019522850 A JP 2019522850A JP 2019537438 A5 JP2019537438 A5 JP 2019537438A5
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- 229920001184 polypeptide Polymers 0.000 claims description 68
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 68
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- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 22
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- DENYZIUJOTUUNY-MRXNPFEDSA-N (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one Chemical compound FC=1C=C2C=3C=4C(CN5[C@@](C4NC3C1)(CCC5)C)=NNC2=O DENYZIUJOTUUNY-MRXNPFEDSA-N 0.000 claims description 2
- CTLOSZHDGZLOQE-UHFFFAOYSA-N 14-methoxy-9-[(4-methylpiperazin-1-yl)methyl]-9,19-diazapentacyclo[10.7.0.02,6.07,11.013,18]nonadeca-1(12),2(6),7(11),13(18),14,16-hexaene-8,10-dione Chemical compound O=C1C2=C3C=4C(OC)=CC=CC=4NC3=C3CCCC3=C2C(=O)N1CN1CCN(C)CC1 CTLOSZHDGZLOQE-UHFFFAOYSA-N 0.000 claims description 2
- DNCYBUMDUBHIJZ-UHFFFAOYSA-N 1h-pyrimidin-6-one Chemical compound O=C1C=CN=CN1 DNCYBUMDUBHIJZ-UHFFFAOYSA-N 0.000 claims description 2
- HRYKZAKEAVZGJD-UHFFFAOYSA-N 2-methyl-3,5,7,8-tetrahydro-4h-thiopyrano[4,3-d]pyrimidin-4-one Chemical compound C1CSCC2=C1N=C(C)NC2=O HRYKZAKEAVZGJD-UHFFFAOYSA-N 0.000 claims description 2
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- XJGXCBHXFWBOTN-UHFFFAOYSA-N 4-[[4-fluoro-3-[2-(trifluoromethyl)-6,8-dihydro-5h-[1,2,4]triazolo[1,5-a]pyrazine-7-carbonyl]phenyl]methyl]-2h-phthalazin-1-one Chemical compound C1CN2N=C(C(F)(F)F)N=C2CN1C(=O)C1=CC(CC=2C3=CC=CC=C3C(=O)NN=2)=CC=C1F XJGXCBHXFWBOTN-UHFFFAOYSA-N 0.000 claims description 2
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- HMABYWSNWIZPAG-UHFFFAOYSA-N rucaparib Chemical compound C1=CC(CNC)=CC=C1C(N1)=C2CCNC(=O)C3=C2C1=CC(F)=C3 HMABYWSNWIZPAG-UHFFFAOYSA-N 0.000 claims description 2
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662416131P | 2016-11-01 | 2016-11-01 | |
| US62/416,131 | 2016-11-01 | ||
| US201662427775P | 2016-11-29 | 2016-11-29 | |
| US62/427,775 | 2016-11-29 | ||
| PCT/US2017/059619 WO2018085469A2 (en) | 2016-11-01 | 2017-11-01 | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019537438A JP2019537438A (ja) | 2019-12-26 |
| JP2019537438A5 true JP2019537438A5 (https=) | 2020-12-17 |
Family
ID=62075645
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019522850A Withdrawn JP2019537438A (ja) | 2016-11-01 | 2017-11-01 | Ｔｉｍ−３（ｔ細胞イムノグロブリンおよびムチンタンパク質３）に対する抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20190284280A1 (https=) |
| EP (2) | EP3689419A1 (https=) |
| JP (1) | JP2019537438A (https=) |
| KR (1) | KR20190098741A (https=) |
| CN (1) | CN110062885A (https=) |
| AU (1) | AU2017354071A1 (https=) |
| BR (1) | BR112019008861A2 (https=) |
| CA (1) | CA3041685A1 (https=) |
| IL (1) | IL266230A (https=) |
| MA (2) | MA50677A (https=) |
| MX (1) | MX2019005116A (https=) |
| SG (2) | SG11201903867YA (https=) |
| WO (1) | WO2018085469A2 (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA201792184A1 (ru) | 2015-04-01 | 2018-04-30 | Анаптисбайо, Инк. | Антитела, направленные против т-клеточного иммуноглобулина и белка муцина 3 (tim-3) |
| EA201792573A1 (ru) | 2015-05-21 | 2018-04-30 | Харпун Терапьютикс, Инк. | Триспецифические связанные белки и способы их применения |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| MY200602A (en) | 2016-07-14 | 2024-01-04 | Bristol Myers Squibb Co | Antibodies against tim3 and uses thereof |
| SG11201903867YA (en) | 2016-11-01 | 2019-05-30 | Anaptysbio Inc | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
| CA3041684C (en) * | 2016-11-01 | 2023-09-26 | Anaptysbio, Inc. | Antibodies directed against programmed death- 1 (pd-1) |
| PT3565844T (pt) | 2017-01-09 | 2023-05-02 | Tesaro Inc | Métodos de tratamento de cancro com anticorpos anti-pd-1 |
| MX2019008208A (es) | 2017-01-09 | 2019-12-11 | Tesaro Inc | Métodos para tratar el cáncer con anticuerpos anti-tim-3. |
| TWI879716B (zh) | 2017-05-09 | 2025-04-11 | 美商提薩羅有限公司 | 治療癌症的組合療法 |
| AU2018265856B2 (en) | 2017-05-12 | 2023-04-27 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
| AU2018270112A1 (en) | 2017-05-18 | 2019-12-12 | Tesaro, Inc. | Combination therapies for treating cancer |
| KR20250016494A (ko) | 2017-09-26 | 2025-02-03 | 테사로, 인코포레이티드 | 니라파립 제제 |
| EP3697442A4 (en) | 2017-09-30 | 2021-07-07 | Tesaro, Inc. | COMBINATION THERAPIES FOR TREATMENT OF CANCER |
| SG11202002499TA (en) | 2017-10-06 | 2020-04-29 | Tesaro Inc | Combination therapies and uses thereof |
| HRP20241268T1 (hr) | 2017-10-13 | 2024-12-06 | Harpoon Therapeutics, Inc. | Trispecifični proteini i postupci primjene |
| IL315737A (en) | 2017-10-13 | 2024-11-01 | Harpoon Therapeutics Inc | B-cell maturation antigen-binding proteins |
| US12134645B2 (en) * | 2018-08-21 | 2024-11-05 | Albert Einstein College Of Medicine | Monoclonal antibodies against human tim-3 |
| TWI852940B (zh) | 2018-09-04 | 2024-08-21 | 美商泰沙羅公司 | 治療癌症之方法 |
| WO2020061482A1 (en) | 2018-09-21 | 2020-03-26 | Harpoon Therapeutics, Inc. | Egfr binding proteins and methods of use |
| SG11202103022WA (en) | 2018-09-25 | 2021-04-29 | Harpoon Therapeutics Inc | Dll3 binding proteins and methods of use |
| WO2020072797A1 (en) | 2018-10-03 | 2020-04-09 | Tesaro, Inc. | Niraparib salts |
| US20210347758A1 (en) | 2018-10-03 | 2021-11-11 | Tesaro, Inc. | Crystalline Forms of Niraparib Freebase |
| EP3873612A2 (en) * | 2018-11-01 | 2021-09-08 | Merck Patent GmbH | Methods of administering anti-tim-3 antibodies |
| CN113272017A (zh) * | 2018-11-01 | 2021-08-17 | 默克专利有限公司 | 抗tim-3抗体 |
| CN113614109A (zh) | 2018-12-21 | 2021-11-05 | Ose免疫疗法公司 | 双功能抗pd-1/il-7分子 |
| WO2020165374A1 (en) | 2019-02-14 | 2020-08-20 | Ose Immunotherapeutics | Bifunctional molecule comprising il-15ra |
| AU2020281535A1 (en) | 2019-05-24 | 2022-01-27 | Merck Patent Gmbh | Combination therapies using CDK inhibitors |
| WO2021024020A1 (en) | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
| CN113164601B (zh) * | 2019-09-19 | 2023-09-29 | 上药生物治疗（香港）有限公司 | 一种分离的抗原结合蛋白及其用途 |
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- 2017-11-01 SG SG11201903867YA patent/SG11201903867YA/en unknown
- 2017-11-01 JP JP2019522850A patent/JP2019537438A/ja not_active Withdrawn
- 2017-11-01 SG SG10201913308PA patent/SG10201913308PA/en unknown
- 2017-11-01 CN CN201780075954.0A patent/CN110062885A/zh active Pending
- 2017-11-01 US US16/346,463 patent/US20190284280A1/en not_active Abandoned
- 2017-11-01 EP EP20150611.0A patent/EP3689419A1/en not_active Withdrawn
- 2017-11-01 EP EP17867255.6A patent/EP3535586A4/en not_active Withdrawn
- 2017-11-01 BR BR112019008861-0A patent/BR112019008861A2/pt not_active IP Right Cessation
- 2017-11-01 MA MA050677A patent/MA50677A/fr unknown
- 2017-11-01 WO PCT/US2017/059619 patent/WO2018085469A2/en not_active Ceased
- 2017-11-01 KR KR1020197015227A patent/KR20190098741A/ko not_active Ceased
- 2017-11-01 CA CA3041685A patent/CA3041685A1/en not_active Abandoned
- 2017-11-01 AU AU2017354071A patent/AU2017354071A1/en not_active Abandoned
- 2017-11-01 MA MA046113A patent/MA46113A/fr unknown
- 2017-11-01 MX MX2019005116A patent/MX2019005116A/es unknown
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2019
- 2019-04-24 IL IL266230A patent/IL266230A/en unknown
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2021
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2023
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2025
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