JP2019535286A - 乳がん患者の化学治療の有用性を予測する方法 - Google Patents

乳がん患者の化学治療の有用性を予測する方法 Download PDF

Info

Publication number
JP2019535286A
JP2019535286A JP2019527430A JP2019527430A JP2019535286A JP 2019535286 A JP2019535286 A JP 2019535286A JP 2019527430 A JP2019527430 A JP 2019527430A JP 2019527430 A JP2019527430 A JP 2019527430A JP 2019535286 A JP2019535286 A JP 2019535286A
Authority
JP
Japan
Prior art keywords
chemotherapy
breast cancer
usefulness
genes
expression level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019527430A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019535286A5 (enExample
Inventor
レ チョ、サン
レ チョ、サン
ホ ムン、ユン
ホ ムン、ユン
イル ハン、チン
イル ハン、チン
キ シン、ヨン
キ シン、ヨン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gencurix Inc
Original Assignee
Gencurix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gencurix Inc filed Critical Gencurix Inc
Publication of JP2019535286A publication Critical patent/JP2019535286A/ja
Publication of JP2019535286A5 publication Critical patent/JP2019535286A5/ja
Priority to JP2022106805A priority Critical patent/JP7430415B2/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019527430A 2016-11-23 2017-11-23 乳がん患者の化学治療の有用性を予測する方法 Pending JP2019535286A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022106805A JP7430415B2 (ja) 2016-11-23 2022-07-01 乳がん患者の化学治療の有用性を予測する方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020160156824A KR101950717B1 (ko) 2016-11-23 2016-11-23 유방암 환자의 화학치료 유용성 예측 방법
KR10-2016-0156824 2016-11-23
PCT/KR2017/013404 WO2018097614A2 (ko) 2016-11-23 2017-11-23 유방암 환자의 화학치료 유용성 예측 방법

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022106805A Division JP7430415B2 (ja) 2016-11-23 2022-07-01 乳がん患者の化学治療の有用性を予測する方法

Publications (2)

Publication Number Publication Date
JP2019535286A true JP2019535286A (ja) 2019-12-12
JP2019535286A5 JP2019535286A5 (enExample) 2020-07-30

Family

ID=62196020

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019527430A Pending JP2019535286A (ja) 2016-11-23 2017-11-23 乳がん患者の化学治療の有用性を予測する方法
JP2022106805A Active JP7430415B2 (ja) 2016-11-23 2022-07-01 乳がん患者の化学治療の有用性を予測する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022106805A Active JP7430415B2 (ja) 2016-11-23 2022-07-01 乳がん患者の化学治療の有用性を予測する方法

Country Status (7)

Country Link
US (1) US10718030B2 (enExample)
EP (1) EP3524690B1 (enExample)
JP (2) JP2019535286A (enExample)
KR (1) KR101950717B1 (enExample)
CN (2) CN116377075A (enExample)
ES (1) ES2963390T3 (enExample)
WO (1) WO2018097614A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022141708A (ja) * 2016-11-23 2022-09-29 ジェンキュリクス インク 乳がん患者の化学治療の有用性を予測する方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220221460A1 (en) * 2019-03-08 2022-07-14 Seoul National University R&Db Foundation Method of quantifying her2 in breast cancer sample by mass spectrometry and scoring her2 status using the same
KR102221206B1 (ko) * 2019-03-08 2021-03-02 서울대학교산학협력단 유방암 샘플에서 질량분석법 의한 her2 정량 방법 및 이를 이용한 her2 상태 스코어링
CN111118146B (zh) * 2020-02-10 2020-08-25 山东大学齐鲁医院(青岛) LncRNA在乳腺癌化疗相关心肌损伤患者诊断中的应用
KR102490338B1 (ko) * 2020-03-24 2023-01-19 (의료)길의료재단 질병의 치료 및 예방을 위한 신약 타겟 유전자 예측 방법
KR102422610B1 (ko) * 2020-05-12 2022-07-18 서울대학교 산학협력단 초기 유방암 환자의 예후 예측 방법
JP7446376B1 (ja) 2022-09-06 2024-03-08 株式会社キャタラー パティキュレートフィルタ

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006129880A (ja) * 2002-03-13 2006-05-25 Genomic Health Inc 生検腫瘍組織での遺伝子発現プロファイリング
US20090215054A1 (en) * 2005-12-13 2009-08-27 Carter Scott L Prognosis indicators for solid human tumors
US20090311700A1 (en) * 2006-09-27 2009-12-17 Siemens Healthcare Diagnositcs Inc. Methods for Breast Cancer Prognosis
JP2011526487A (ja) * 2008-07-02 2011-10-13 セントロ・デ・インベステイガイシオネス・エネルゲテイカス，メデイオアムビエンタレス・イ・テクノロヒカス・（セ．イ．エ．エメ．ア．テ．） 乳癌のゲノムフィンガープリント
JP2015518724A (ja) * 2012-05-22 2015-07-06 ナノストリング テクノロジーズ，インコーポレイティド Ｎａｎｏ４６遺伝子、及び乳癌転帰を予測する方法
JP2016516426A (ja) * 2013-04-18 2016-06-09 ジェンキュリクス インクＧｅｎｃｕｒｉｘ Ｉｎｃ． 早期乳癌の予後予測診断用遺伝子マーカーおよびその用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2624086A1 (en) * 2005-09-28 2007-04-05 H. Lee Moffitt Cancer Center Individualized cancer treatments
KR101421326B1 (ko) * 2010-03-30 2014-07-21 서울대학교산학협력단 유방암 예후 예측을 위한 조성물 및 이를 포함하는 키트
MX2012011167A (es) * 2010-03-31 2013-02-07 Sividon Diagnostics Gmbh Metodo para prediccion de recurrencia de cancer de mama bajo tratamiento endocrino.
KR101287600B1 (ko) * 2011-01-04 2013-07-18 주식회사 젠큐릭스 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법
US9670549B2 (en) * 2011-11-10 2017-06-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Gene expression signatures of neoplasm responsiveness to therapy
KR101725985B1 (ko) * 2013-01-28 2017-04-13 주식회사 젠큐릭스 초기유방암의 예후 예측용 유전자 및 이를 이용한 초기유방암의 예후예측 방법
KR101748867B1 (ko) 2013-04-19 2017-06-20 주식회사 젠큐릭스 조기 유방암 예후 예측 진단용 자동화 시스템
KR101632628B1 (ko) * 2014-03-31 2016-06-23 제이더블유중외제약 주식회사 유방암 재발 또는 전이 억제용 제제의 스크리닝 방법
US10174382B2 (en) * 2015-05-13 2019-01-08 University Of Notre Dame Breast cancer prognostication and screening kits and methods of using same
KR101950717B1 (ko) * 2016-11-23 2019-02-21 주식회사 젠큐릭스 유방암 환자의 화학치료 유용성 예측 방법
KR101896545B1 (ko) * 2016-11-25 2018-09-07 주식회사 젠큐릭스 유방암 환자의 예후 예측 방법

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006129880A (ja) * 2002-03-13 2006-05-25 Genomic Health Inc 生検腫瘍組織での遺伝子発現プロファイリング
US20090215054A1 (en) * 2005-12-13 2009-08-27 Carter Scott L Prognosis indicators for solid human tumors
US20090311700A1 (en) * 2006-09-27 2009-12-17 Siemens Healthcare Diagnositcs Inc. Methods for Breast Cancer Prognosis
JP2011526487A (ja) * 2008-07-02 2011-10-13 セントロ・デ・インベステイガイシオネス・エネルゲテイカス，メデイオアムビエンタレス・イ・テクノロヒカス・（セ．イ．エ．エメ．ア．テ．） 乳癌のゲノムフィンガープリント
JP2015518724A (ja) * 2012-05-22 2015-07-06 ナノストリング テクノロジーズ，インコーポレイティド Ｎａｎｏ４６遺伝子、及び乳癌転帰を予測する方法
JP2016516426A (ja) * 2013-04-18 2016-06-09 ジェンキュリクス インクＧｅｎｃｕｒｉｘ Ｉｎｃ． 早期乳癌の予後予測診断用遺伝子マーカーおよびその用途

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022141708A (ja) * 2016-11-23 2022-09-29 ジェンキュリクス インク 乳がん患者の化学治療の有用性を予測する方法

Also Published As

Publication number Publication date
EP3524690A4 (en) 2020-06-17
EP3524690C0 (en) 2023-08-30
WO2018097614A2 (ko) 2018-05-31
US20180216198A1 (en) 2018-08-02
US10718030B2 (en) 2020-07-21
WO2018097614A3 (ko) 2018-08-09
KR20180058118A (ko) 2018-05-31
ES2963390T3 (es) 2024-03-26
CN116377075A (zh) 2023-07-04
EP3524690B1 (en) 2023-08-30
EP3524690A2 (en) 2019-08-14
JP2022141708A (ja) 2022-09-29
KR101950717B1 (ko) 2019-02-21
JP7430415B2 (ja) 2024-02-13
CN110023512A (zh) 2019-07-16

Similar Documents

Publication Publication Date Title
JP7228896B2 (ja) 乳がん患者の予後の予測方法
JP7430415B2 (ja) 乳がん患者の化学治療の有用性を予測する方法
JP7042784B2 (ja) 遺伝子発現を用いた前立腺癌の予後を定量化する方法
JP6351112B2 (ja) 前立腺癌の予後を定量化するための遺伝子発現プロフィールアルゴリズムおよび試験
CN105339797B (zh) 早期乳腺癌的预后预测诊断用基因标记物及其用途
MX2013013746A (es) Biomarcadores para cancer de pulmon.
US11840733B2 (en) Method for predicting prognosis of breast cancer patient
CA2889276A1 (en) Method for identifying a target molecular profile associated with a target cell population
US11845993B2 (en) Methods for identifying prostate cancer
KR101504818B1 (ko) 위암에 대한 예후 예측 시스템
CN115472294A (zh) 预测小细胞转化肺腺癌患者转化速度的模型及其构建方法

Legal Events

Date Code Title Description
A80 Written request to apply exceptions to lack of novelty of invention

Free format text: JAPANESE INTERMEDIATE CODE: A80

Effective date: 20190729

Free format text: JAPANESE INTERMEDIATE CODE: A801

Effective date: 20190729

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200617

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20200617

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210706

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20211006

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20211125

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20220301