JP2019535240A5 - - Google Patents
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- Publication number
- JP2019535240A5 JP2019535240A5 JP2019520527A JP2019520527A JP2019535240A5 JP 2019535240 A5 JP2019535240 A5 JP 2019535240A5 JP 2019520527 A JP2019520527 A JP 2019520527A JP 2019520527 A JP2019520527 A JP 2019520527A JP 2019535240 A5 JP2019535240 A5 JP 2019535240A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- polypeptide
- cell
- cells
- onui
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022066868A JP2022103174A (ja) | 2016-10-17 | 2022-04-14 | ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662409163P | 2016-10-17 | 2016-10-17 | |
| US62/409,163 | 2016-10-17 | ||
| US201662414260P | 2016-10-28 | 2016-10-28 | |
| US62/414,260 | 2016-10-28 | ||
| PCT/US2017/057014 WO2018075541A1 (en) | 2016-10-17 | 2017-10-17 | TGFβR2 ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022066868A Division JP2022103174A (ja) | 2016-10-17 | 2022-04-14 | ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019535240A JP2019535240A (ja) | 2019-12-12 |
| JP2019535240A5 true JP2019535240A5 (enExample) | 2020-11-19 |
| JP7060591B2 JP7060591B2 (ja) | 2022-04-26 |
Family
ID=62018976
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019520527A Active JP7060591B2 (ja) | 2016-10-17 | 2017-10-17 | ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 |
| JP2022066868A Withdrawn JP2022103174A (ja) | 2016-10-17 | 2022-04-14 | ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022066868A Withdrawn JP2022103174A (ja) | 2016-10-17 | 2022-04-14 | ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11530395B2 (enExample) |
| EP (1) | EP3526334A4 (enExample) |
| JP (2) | JP7060591B2 (enExample) |
| CN (1) | CN110050066A (enExample) |
| AU (1) | AU2017346683B2 (enExample) |
| CA (1) | CA3040157A1 (enExample) |
| MA (1) | MA46543A (enExample) |
| WO (1) | WO2018075541A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| SG11201901757YA (en) | 2016-09-08 | 2019-03-28 | Bluebird Bio Inc | Pd-1 homing endonuclease variants, compositions, and methods of use |
| EP3765094A4 (en) | 2018-03-15 | 2021-12-22 | KSQ Therapeutics, Inc. | GENE REGULATORY COMPOSITIONS AND PROCEDURES FOR IMPROVED IMMUNOTHERAPY |
| CN110904045A (zh) * | 2018-09-17 | 2020-03-24 | 中国科学院动物研究所 | 经修饰的t细胞、其制备方法及用途 |
| CA3122094A1 (en) | 2018-12-10 | 2020-06-18 | Bluebird Bio, Inc. | Pdcd-1 homing endonuclease variants |
| JP2022513750A (ja) * | 2018-12-10 | 2022-02-09 | ２セブンティ バイオ インコーポレイテッド | ホーミングエンドヌクレアーゼバリアント |
| SG11202111372VA (en) * | 2019-05-01 | 2021-11-29 | Juno Therapeutics Inc | Cells expressing a chimeric receptor from a modified cd247 locus, related polynucleotides and methods |
| CA3136737A1 (en) * | 2019-05-01 | 2020-11-05 | Juno Therapeutics, Inc. | Cells expressing a recombinant receptor from a modified tgfbr2 locus, related polynucleotides and methods |
| WO2023081900A1 (en) * | 2021-11-08 | 2023-05-11 | Juno Therapeutics, Inc. | Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
| US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| GB8918616D0 (en) | 1989-08-15 | 1989-09-27 | Univ Glasgow | Herpes simplex virus type 1 mutant |
| US5804413A (en) | 1992-07-31 | 1998-09-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Herpes simplex virus strains for gene transfer |
| GB9415319D0 (en) | 1994-07-29 | 1994-09-21 | Medical Res Council | HSV viral vector |
| US5846782A (en) | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US6093570A (en) | 1995-06-07 | 2000-07-25 | The University Of North Carolina At Chapel Hill | Helper virus-free AAV production |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| EP1002119A1 (en) | 1997-07-31 | 2000-05-24 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Targeted hsv vectors |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| FR2777909B1 (fr) | 1998-04-24 | 2002-08-02 | Pasteur Institut | Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex |
| US6692736B2 (en) | 2000-03-24 | 2004-02-17 | Cell Genesys, Inc. | Cell-specific adenovirus vectors comprising an internal ribosome entry site |
| US7465583B2 (en) | 2000-06-01 | 2008-12-16 | The University Of North Carolina At Chapel Hill | Duplexed parvovirus vectors |
| FR2872170B1 (fr) | 2004-06-25 | 2006-11-10 | Centre Nat Rech Scient Cnrse | Lentivirus non interactif et non replicatif, preparation et utilisations |
| EP1828390B1 (en) | 2004-12-15 | 2012-06-13 | The University Of North Carolina At Chapel Hill | Chimeric vectors |
| AU2007347328B2 (en) * | 2007-02-19 | 2013-03-07 | Cellectis | LAGLIDADG homing endonuclease variants having novel substrate specificity and use thereof |
| ES2422291T3 (es) * | 2007-10-31 | 2013-09-10 | Prec Biosciences Inc | Meganucleasas monocatenarias diseñadas racionalmente con secuencias de reconocimiento no palindrómicas |
| US20110239315A1 (en) | 2009-01-12 | 2011-09-29 | Ulla Bonas | Modular dna-binding domains and methods of use |
| EP2396343B1 (en) | 2009-02-11 | 2017-05-17 | The University of North Carolina At Chapel Hill | Modified virus vectors and methods of making and using the same |
| WO2010093966A2 (en) | 2009-02-12 | 2010-08-19 | Fred Hutchinson Cancer Research Center | Generation of a dna nicking enzyme that stimulates site-specific gene conversion from a homing endonuclease |
| US9169494B2 (en) | 2010-01-12 | 2015-10-27 | The University Of North Carolina At Chapel Hill | Restrictive inverted terminal repeats for viral vectors |
| WO2011097456A2 (en) | 2010-02-05 | 2011-08-11 | The University Of North Carolina At Chapel Hill | Compositions and methods for enhanced parvovirus transduction |
| WO2011156430A2 (en) * | 2010-06-07 | 2011-12-15 | Fred Hutchinson Cancer Research Center | Generation and expression of engineered i-onui endonuclease and its homologues and uses thereof |
| US8673557B2 (en) | 2011-02-28 | 2014-03-18 | Seattle Children's Research Institute | Coupling endonucleases with end-processing enzymes drives high efficiency gene disruption |
| US8450107B1 (en) | 2011-11-30 | 2013-05-28 | The Broad Institute Inc. | Nucleotide-specific recognition sequences for designer TAL effectors |
| WO2014172584A1 (en) * | 2013-04-17 | 2014-10-23 | Baylor College Of Medicine | IMMUNOSUPPRESSIVE TGF-β SIGNAL CONVERTER |
| JP6608807B2 (ja) * | 2013-05-29 | 2019-11-20 | セレクティス | Ｒｎａガイドｃａｓヌクレアーゼ系を用いることによって免疫療法のためにｔ細胞を操作するための方法 |
| CA2913871C (en) * | 2013-05-31 | 2021-07-13 | Cellectis | A laglidadg homing endonuclease cleaving the c-c chemokine receptor type-5 (ccr5) gene and uses thereof |
| CA2913872C (en) * | 2013-05-31 | 2022-01-18 | Cellectis | A laglidadg homing endonuclease cleaving the t-cell receptor alpha gene and uses thereof |
| EP3027204B1 (en) | 2013-07-29 | 2022-01-05 | 2seventy bio, Inc. | Multipartite signaling proteins and uses thereof |
| CA3031785A1 (en) | 2016-07-25 | 2018-02-01 | Bluebird Bio, Inc. | Bcl11a homing endonuclease variants, compositions, and methods of use |
| EP3500696A4 (en) | 2016-08-16 | 2020-04-08 | Bluebird Bio, Inc. | VARIANTS OF IL-10 ALPHA RECEPTOR HOMING ENDONUCLEASE, COMPOSITIONS AND METHODS OF USE |
| US20190262398A1 (en) | 2016-08-23 | 2019-08-29 | Bluebird Bio, Inc. | Tim3 homing endonuclease variants, compositions, and methods of use |
| SG11201901757YA (en) | 2016-09-08 | 2019-03-28 | Bluebird Bio Inc | Pd-1 homing endonuclease variants, compositions, and methods of use |
| SG11201903230QA (en) | 2016-10-11 | 2019-05-30 | Bluebird Bio Inc | TCRa HOMING ENDONUCLEASE VARIANTS |
-
2017
- 2017-10-17 US US16/341,228 patent/US11530395B2/en active Active
- 2017-10-17 JP JP2019520527A patent/JP7060591B2/ja active Active
- 2017-10-17 WO PCT/US2017/057014 patent/WO2018075541A1/en not_active Ceased
- 2017-10-17 CN CN201780076229.5A patent/CN110050066A/zh active Pending
- 2017-10-17 MA MA046543A patent/MA46543A/fr unknown
- 2017-10-17 AU AU2017346683A patent/AU2017346683B2/en active Active
- 2017-10-17 CA CA3040157A patent/CA3040157A1/en active Pending
- 2017-10-17 EP EP17861537.3A patent/EP3526334A4/en not_active Withdrawn
-
2022
- 2022-04-14 JP JP2022066868A patent/JP2022103174A/ja not_active Withdrawn
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