JP7060591B2 - ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 - Google Patents

ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 Download PDF

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JP7060591B2
JP7060591B2 JP2019520527A JP2019520527A JP7060591B2 JP 7060591 B2 JP7060591 B2 JP 7060591B2 JP 2019520527 A JP2019520527 A JP 2019520527A JP 2019520527 A JP2019520527 A JP 2019520527A JP 7060591 B2 JP7060591 B2 JP 7060591B2
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polypeptide
tgfβr2
cells
certain embodiments
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JP2019535240A (ja
JP2019535240A5 (enExample
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ジョーダン ジャージョル，
カイル ヘイヴンズ，
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２セブンティ バイオ インコーポレイテッド
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    • A61P35/00—Antineoplastic agents
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
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JP2019520527A 2016-10-17 2017-10-17 ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法 Active JP7060591B2 (ja)

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JP2022066868A JP2022103174A (ja) 2016-10-17 2022-04-14 ＴＧＦβＲ２エンドヌクレアーゼバリアント、組成物、および使用方法

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US201662409163P 2016-10-17 2016-10-17
US62/409,163 2016-10-17
US201662414260P 2016-10-28 2016-10-28
US62/414,260 2016-10-28
PCT/US2017/057014 WO2018075541A1 (en) 2016-10-17 2017-10-17 TGFβR2 ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE

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CN110904045A (zh) * 2018-09-17 2020-03-24 中国科学院动物研究所 经修饰的t细胞、其制备方法及用途
CA3122094A1 (en) 2018-12-10 2020-06-18 Bluebird Bio, Inc. Pdcd-1 homing endonuclease variants
JP2022513750A (ja) * 2018-12-10 2022-02-09 ２セブンティ バイオ インコーポレイテッド ホーミングエンドヌクレアーゼバリアント
SG11202111372VA (en) * 2019-05-01 2021-11-29 Juno Therapeutics Inc Cells expressing a chimeric receptor from a modified cd247 locus, related polynucleotides and methods
CA3136737A1 (en) * 2019-05-01 2020-11-05 Juno Therapeutics, Inc. Cells expressing a recombinant receptor from a modified tgfbr2 locus, related polynucleotides and methods
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AU2017346683B2 (en) 2024-04-18
JP2019535240A (ja) 2019-12-12
CN110050066A (zh) 2019-07-23
EP3526334A4 (en) 2020-09-30
WO2018075541A1 (en) 2018-04-26
JP2022103174A (ja) 2022-07-07
US20200123515A1 (en) 2020-04-23
AU2017346683A1 (en) 2019-05-09
MA46543A (fr) 2019-08-21
US11530395B2 (en) 2022-12-20
CA3040157A1 (en) 2018-04-26
EP3526334A1 (en) 2019-08-21

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