JP2019534025A5 - - Google Patents

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Publication number
JP2019534025A5
JP2019534025A5 JP2019524385A JP2019524385A JP2019534025A5 JP 2019534025 A5 JP2019534025 A5 JP 2019534025A5 JP 2019524385 A JP2019524385 A JP 2019524385A JP 2019524385 A JP2019524385 A JP 2019524385A JP 2019534025 A5 JP2019534025 A5 JP 2019534025A5
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JP
Japan
Prior art keywords
nucleoside
oligonucleotide
region
capture probe
modified
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JP2019524385A
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English (en)
Japanese (ja)
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JP7033591B2 (ja
JP2019534025A (ja
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Priority claimed from PCT/EP2017/078695 external-priority patent/WO2018087200A1/en
Publication of JP2019534025A publication Critical patent/JP2019534025A/ja
Publication of JP2019534025A5 publication Critical patent/JP2019534025A5/ja
Application granted granted Critical
Publication of JP7033591B2 publication Critical patent/JP7033591B2/ja
Expired - Fee Related legal-status Critical Current
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JP2019524385A 2016-11-11 2017-11-09 治療用オリゴヌクレオチドの捕捉および検出 Expired - Fee Related JP7033591B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16198340 2016-11-11
EP16198340.8 2016-11-11
PCT/EP2017/078695 WO2018087200A1 (en) 2016-11-11 2017-11-09 Therapeutic oligonucleotides capture and detection

Publications (3)

Publication Number Publication Date
JP2019534025A JP2019534025A (ja) 2019-11-28
JP2019534025A5 true JP2019534025A5 (https=) 2020-01-16
JP7033591B2 JP7033591B2 (ja) 2022-03-10

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ID=60413165

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JP2019524385A Expired - Fee Related JP7033591B2 (ja) 2016-11-11 2017-11-09 治療用オリゴヌクレオチドの捕捉および検出

Country Status (4)

Country Link
US (1) US20190284621A1 (https=)
EP (1) EP3538671A1 (https=)
JP (1) JP7033591B2 (https=)
WO (1) WO2018087200A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017289204A1 (en) 2016-07-01 2019-01-17 F. Hoffmann-La Roche Ag Antisense oligonucleotides for modulating HTRA1 expression
WO2018130585A1 (en) * 2017-01-13 2018-07-19 Roche Innovation Center Copenhagen A/S Antisense oligonucleotides for modulating relb expression
US20190055564A1 (en) * 2017-06-01 2019-02-21 F. Hoffmann-La Roche Ag Antisense oligonucleotides for modulating htra1 expression
US20240175077A1 (en) * 2019-11-14 2024-05-30 Sekisui Medical Co., Ltd. Method for detecting or quantifying oligonucleotide
CN121344163A (zh) * 2020-01-16 2026-01-16 Dnae诊断有限公司 用于分离靶多核苷酸的组合物、试剂盒和方法
US20230407374A1 (en) * 2020-11-09 2023-12-21 Children's Medical Center Corporation Systems and methods for high throughput screening of molecular interactions
GB202217984D0 (en) * 2022-11-30 2023-01-11 Qbiotix Ltd Assays

Family Cites Families (25)

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Publication number Priority date Publication date Assignee Title
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
AU9063398A (en) 1997-09-12 1999-04-05 Exiqon A/S Oligonucleotide analogues
CZ296576B6 (cs) 1999-02-12 2006-04-12 Sankyo Company Limited Nukleosidový analog a oligonukleotidový analog a farmaceutický prostredek, sonda a primer s jeho obsahem
EP1178999B1 (en) 1999-05-04 2007-03-14 Santaris Pharma A/S L-ribo-lna analogues
AU767490B2 (en) 1999-11-12 2003-11-13 Isis Pharmaceuticals, Inc. Method for quantitating oligonucleotides
US9045518B2 (en) 2002-11-18 2015-06-02 Santaris Pharma A/S Amino-LNA, thio-LNA and alpha-L-oxy-LN
EP1896617B1 (en) 2005-05-31 2013-01-02 Life Technologies Corporation Multiplex amplification of short nucleic acids
ATE532878T1 (de) * 2005-08-24 2011-11-15 Life Technologies Corp Verfahren zur quantifizierung von sirnas, mirnas und polymorphen mirnas
EP2458011B1 (en) 2005-10-03 2013-07-24 Life Technologies Corporation Compositions, methods, and kits for amplifying nucleic acids
JP5342881B2 (ja) 2006-01-27 2013-11-13 アイシス ファーマシューティカルズ， インコーポレーテッド ６−修飾された二環式核酸類似体
AU2007249349B2 (en) 2006-05-11 2012-03-08 Isis Pharmaceuticals, Inc. 5'-Modified bicyclic nucleic acid analogs
US7666854B2 (en) 2006-05-11 2010-02-23 Isis Pharmaceuticals, Inc. Bis-modified bicyclic nucleic acid analogs
EP1914317A1 (en) 2006-10-21 2008-04-23 Biolytix AG A method for qualitative and quantitative detection of short nucleic acid sequences of about 8 to 50 nucleotides in length
EP2170917B1 (en) 2007-05-30 2012-06-27 Isis Pharmaceuticals, Inc. N-substituted-aminomethylene bridged bicyclic nucleic acid analogs
EP2173760B2 (en) 2007-06-08 2015-11-04 Isis Pharmaceuticals, Inc. Carbocyclic bicyclic nucleic acid analogs
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EP2462153B1 (en) 2009-08-06 2015-07-29 Isis Pharmaceuticals, Inc. Bicyclic cyclohexose nucleic acid analogs
EP2580228B1 (en) 2010-06-08 2016-03-23 Ionis Pharmaceuticals, Inc. Substituted 2'-amino and 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom
CN104136451A (zh) 2011-09-07 2014-11-05 玛瑞纳生物技术有限公司 具有构象限制的单体的核酸化合物的合成和用途
US10941396B2 (en) 2012-02-27 2021-03-09 Becton, Dickinson And Company Compositions and kits for molecular counting
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WO2013153911A1 (ja) 2012-04-12 2013-10-17 国立大学法人東京大学 核酸の定量方法、検出プローブ、検出プローブセット、及び核酸の検出方法
US9816120B2 (en) 2013-01-09 2017-11-14 The Penn State Research Foundation Low sequence bias single-stranded DNA ligation

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