JP2019534025A5 - - Google Patents

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Publication number
JP2019534025A5
JP2019534025A5 JP2019524385A JP2019524385A JP2019534025A5 JP 2019534025 A5 JP2019534025 A5 JP 2019534025A5 JP 2019524385 A JP2019524385 A JP 2019524385A JP 2019524385 A JP2019524385 A JP 2019524385A JP 2019534025 A5 JP2019534025 A5 JP 2019534025A5
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JP
Japan
Prior art keywords
nucleoside
oligonucleotide
region
capture probe
modified
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JP2019524385A
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English (en)
Japanese (ja)
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JP2019534025A (ja
JP7033591B2 (ja
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Priority claimed from PCT/EP2017/078695 external-priority patent/WO2018087200A1/en
Publication of JP2019534025A publication Critical patent/JP2019534025A/ja
Publication of JP2019534025A5 publication Critical patent/JP2019534025A5/ja
Application granted granted Critical
Publication of JP7033591B2 publication Critical patent/JP7033591B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2019524385A 2016-11-11 2017-11-09 治療用オリゴヌクレオチドの捕捉および検出 Expired - Fee Related JP7033591B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16198340.8 2016-11-11
EP16198340 2016-11-11
PCT/EP2017/078695 WO2018087200A1 (en) 2016-11-11 2017-11-09 Therapeutic oligonucleotides capture and detection

Publications (3)

Publication Number Publication Date
JP2019534025A JP2019534025A (ja) 2019-11-28
JP2019534025A5 true JP2019534025A5 (https=) 2020-01-16
JP7033591B2 JP7033591B2 (ja) 2022-03-10

Family

ID=60413165

Family Applications (1)

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JP2019524385A Expired - Fee Related JP7033591B2 (ja) 2016-11-11 2017-11-09 治療用オリゴヌクレオチドの捕捉および検出

Country Status (4)

Country Link
US (1) US20190284621A1 (https=)
EP (1) EP3538671A1 (https=)
JP (1) JP7033591B2 (https=)
WO (1) WO2018087200A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018015722A (es) 2016-07-01 2019-05-27 Hoffmann La Roche Oligonucleotidos antisentido para modular expresion del requisito de alta temperatura a 1 (htra1).
US20190345496A1 (en) * 2017-01-13 2019-11-14 Roche Innovation Center Copenhagen A/S Antisense oligonucleotides for modulating relb expression
US20190055564A1 (en) * 2017-06-01 2019-02-21 F. Hoffmann-La Roche Ag Antisense oligonucleotides for modulating htra1 expression
WO2021095829A1 (ja) * 2019-11-14 2021-05-20 積水メディカル株式会社 オリゴヌクレオチドの検出又は定量方法
ES3036514T3 (en) 2020-01-16 2025-09-19 Dnae Diagnostics Ltd Compositions, kits and methods for isolating target polynucleotides
WO2022099216A1 (en) * 2020-11-09 2022-05-12 Children's Medical Center Corporation Systems and methods for high throughput screening of molecular interactions
GB202217984D0 (en) * 2022-11-30 2023-01-11 Qbiotix Ltd Assays

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Publication number Priority date Publication date Assignee Title
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
JP4236812B2 (ja) 1997-09-12 2009-03-11 エクシコン エ／エス オリゴヌクレオチド類似体
ES2234563T5 (es) 1999-02-12 2018-01-17 Daiichi Sankyo Company, Limited Nuevos análogos de nucleósidos y oligonucleótidos
US7053207B2 (en) 1999-05-04 2006-05-30 Exiqon A/S L-ribo-LNA analogues
AU767490B2 (en) * 1999-11-12 2003-11-13 Isis Pharmaceuticals, Inc. Method for quantitating oligonucleotides
WO2004046160A2 (en) 2002-11-18 2004-06-03 Santaris Pharma A/S Amino-lna, thio-lna and alpha-l-oxy-ln
JP4879975B2 (ja) * 2005-05-31 2012-02-22 アプライド バイオシステムズ リミテッド ライアビリティー カンパニー 短い核酸のマルチプレックス増幅
EP1924713B1 (en) * 2005-08-24 2011-11-09 Life Technologies Corporation A method to quantify sirnas, mirnas and polymorphic mirnas
US20070212704A1 (en) * 2005-10-03 2007-09-13 Applera Corporation Compositions, methods, and kits for amplifying nucleic acids
WO2007090071A2 (en) 2006-01-27 2007-08-09 Isis Pharmaceuticals, Inc. 6-modified bicyclic nucleic acid analogs
US7666854B2 (en) 2006-05-11 2010-02-23 Isis Pharmaceuticals, Inc. Bis-modified bicyclic nucleic acid analogs
AU2007249349B2 (en) 2006-05-11 2012-03-08 Isis Pharmaceuticals, Inc. 5'-Modified bicyclic nucleic acid analogs
EP1914317A1 (en) 2006-10-21 2008-04-23 Biolytix AG A method for qualitative and quantitative detection of short nucleic acid sequences of about 8 to 50 nucleotides in length
CA2688321A1 (en) 2007-05-30 2008-12-11 Isis Pharmaceuticals, Inc. N-substituted-aminomethylene bridged bicyclic nucleic acid analogs
DK2173760T4 (en) 2007-06-08 2016-02-08 Isis Pharmaceuticals Inc Carbocyclic bicyclic nukleinsyreanaloge
AU2008272918B2 (en) 2007-07-05 2012-09-13 Isis Pharmaceuticals, Inc. 6-disubstituted bicyclic nucleic acid analogs
WO2009067647A1 (en) 2007-11-21 2009-05-28 Isis Pharmaceuticals, Inc. Carbocyclic alpha-l-bicyclic nucleic acid analogs
DK2356129T3 (da) 2008-09-24 2013-05-13 Isis Pharmaceuticals Inc Substituerede alpha-L-bicykliske nukleosider
US9012421B2 (en) 2009-08-06 2015-04-21 Isis Pharmaceuticals, Inc. Bicyclic cyclohexose nucleic acid analogs
EP2580228B1 (en) 2010-06-08 2016-03-23 Ionis Pharmaceuticals, Inc. Substituted 2'-amino and 2'-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom
EP2753631A1 (en) 2011-09-07 2014-07-16 Marina Biotech, Inc. Synthesis and uses of nucleic acid compounds with conformationally restricted monomers
CA2865575C (en) * 2012-02-27 2024-01-16 Cellular Research, Inc. Compositions and kits for molecular counting
EP2850092B1 (en) 2012-04-09 2017-03-01 Ionis Pharmaceuticals, Inc. Tricyclic nucleic acid analogs
WO2013153911A1 (ja) * 2012-04-12 2013-10-17 国立大学法人東京大学 核酸の定量方法、検出プローブ、検出プローブセット、及び核酸の検出方法
WO2014110272A1 (en) * 2013-01-09 2014-07-17 The Penn State Research Foundation Low sequence bias single-stranded dna ligation

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