|
CA1331443C
(en)
|
1987-05-29 |
1994-08-16 |
Charlotte A. Kensil |
Saponin adjuvant
|
|
GB8911525D0
(en)
|
1989-05-19 |
1989-07-05 |
Allied Colloids Ltd |
Polymeric composition
|
|
ATE356869T1
(de)
|
1990-01-12 |
2007-04-15 |
Amgen Fremont Inc |
Bildung von xenogenen antikörpern
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
US5766846A
(en)
|
1992-07-10 |
1998-06-16 |
Athena Neurosciences |
Methods of screening for compounds which inhibit soluble β-amyloid peptide production
|
|
US5562909A
(en)
|
1993-07-12 |
1996-10-08 |
Massachusetts Institute Of Technology |
Phosphazene polyelectrolytes as immunoadjuvants
|
|
WO1995006477A1
(en)
|
1993-08-31 |
1995-03-09 |
Gliatech, Inc. |
Inhibition of beta amyloid binding to glycosaminoglycans for treatment of alzheimer's disease
|
|
GB9326174D0
(en)
|
1993-12-22 |
1994-02-23 |
Biocine Sclavo |
Mucosal adjuvant
|
|
US20030072774A1
(en)
|
1994-06-10 |
2003-04-17 |
Diane M. Gajewczyk |
Proteinaceous adjuvants
|
|
US6019982A
(en)
|
1994-08-26 |
2000-02-01 |
The Administrators Of The Tulane Educational Fund |
Mutant enterotoxin effective as a non-toxic oral adjuvant
|
|
FR2726764B1
(fr)
|
1994-11-14 |
1997-01-31 |
Pasteur Merieux Serums Vacc |
Adjuvant pour composition vaccinale
|
|
US6319498B1
(en)
|
1995-03-14 |
2001-11-20 |
Praecis Pharmaceuticals Incorporated |
Modulators of amyloid aggregation
|
|
WO1997021728A1
(en)
|
1995-12-12 |
1997-06-19 |
Karolinska Innovations Ab |
PEPTIDE BINDING THE KLVFF-SEQUENCE OF AMYLOID $g(b)
|
|
US5735814A
(en)
|
1996-04-30 |
1998-04-07 |
Medtronic, Inc. |
Techniques of treating neurodegenerative disorders by brain infusion
|
|
US6043283A
(en)
|
1996-09-20 |
2000-03-28 |
Baylor College Of Medicine |
Tyramine compounds and their neuronal effects
|
|
US6071493A
(en)
|
1996-09-20 |
2000-06-06 |
Baylor College Of Medicine |
Method of screening for an agent that inhibits mononuclear phagocyte-plaque component complex formation
|
|
US7964192B1
(en)
|
1997-12-02 |
2011-06-21 |
Janssen Alzheimer Immunotherapy |
Prevention and treatment of amyloidgenic disease
|
|
TWI239847B
(en)
|
1997-12-02 |
2005-09-21 |
Elan Pharm Inc |
N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
|
|
US7588766B1
(en)
|
2000-05-26 |
2009-09-15 |
Elan Pharma International Limited |
Treatment of amyloidogenic disease
|
|
US20080050367A1
(en)
|
1998-04-07 |
2008-02-28 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6761888B1
(en)
|
2000-05-26 |
2004-07-13 |
Neuralab Limited |
Passive immunization treatment of Alzheimer's disease
|
|
US7179892B2
(en)
|
2000-12-06 |
2007-02-20 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
US6913745B1
(en)
|
1997-12-02 |
2005-07-05 |
Neuralab Limited |
Passive immunization of Alzheimer's disease
|
|
US7790856B2
(en)
|
1998-04-07 |
2010-09-07 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7012061B1
(en)
|
1998-10-19 |
2006-03-14 |
New York University |
Method for increasing the permeability of the blood brain barrier
|
|
UA81216C2
(en)
|
1999-06-01 |
2007-12-25 |
|
Prevention and treatment of amyloid disease
|
|
US20020094335A1
(en)
|
1999-11-29 |
2002-07-18 |
Robert Chalifour |
Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
|
|
KR20080059676A
(ko)
|
1999-11-29 |
2008-06-30 |
뉴로겜 인터내셔널 리미티드 |
알츠하이머 및 아밀로이드 관련 질병의 예방 및 치료용백신
|
|
SI1257584T2
(sl)
|
2000-02-24 |
2013-07-31 |
Washington University St. Louis |
Humanizirana protitelesa, ki veĹľejo amiloidni peptid beta
|
|
AU2007234495A1
(en)
|
2000-09-08 |
2007-12-06 |
Board Of Regents, The University Of Texas System |
Biopanning and rapid analysis of selective interactive ligands (BRASIL)
|
|
TWI255272B
(en)
|
2000-12-06 |
2006-05-21 |
Guriq Basi |
Humanized antibodies that recognize beta amyloid peptide
|
|
US7700751B2
(en)
|
2000-12-06 |
2010-04-20 |
Janssen Alzheimer Immunotherapy |
Humanized antibodies that recognize β-amyloid peptide
|
|
CA2436789A1
(en)
|
2000-12-19 |
2002-08-22 |
Palatin Technologies, Inc. |
Identification of target-specific folding sites in peptides and proteins
|
|
AR038568A1
(es)
|
2002-02-20 |
2005-01-19 |
Hoffmann La Roche |
Anticuerpos anti-a beta y su uso
|
|
MY139983A
(en)
|
2002-03-12 |
2009-11-30 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
AU2003250102B2
(en)
|
2002-07-24 |
2009-09-17 |
Innogenetics N.V. |
Fragments of beta-amyloid as targets for vaccination against alzheimer disease
|
|
US9535076B2
(en)
|
2002-09-12 |
2017-01-03 |
The Regents Of The University Of California |
Methods and compositions for eliciting an amyloid-selective immune response
|
|
WO2004029629A1
(en)
|
2002-09-27 |
2004-04-08 |
Janssen Pharmaceutica N.V. |
N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
|
|
EA012325B1
(ru)
|
2002-12-24 |
2009-08-28 |
Беллус Хелс (Интернэшнл) Лимитед |
Терапевтические составы для лечения болезней, связанных с наличием бета-амилоида
|
|
WO2004071408A2
(en)
|
2003-02-10 |
2004-08-26 |
Applied Molecular Evolution, Inc. |
Aβ BINDING MOLECULES
|
|
CN101367874A
(zh)
*
|
2003-03-28 |
2009-02-18 |
森托科尔公司 |
抗淀粉状蛋白抗体、组合物、方法和用途
|
|
TWI374893B
(en)
|
2003-05-30 |
2012-10-21 |
Janssen Alzheimer Immunotherap |
Humanized antibodies that recognize beta amyloid peptide
|
|
JP2007527865A
(ja)
|
2003-09-12 |
2007-10-04 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
種々の配列を有するタンパク質から形成されたアミロイドに共通の高分子量凝集中間体に特異的なモノクローナル抗体
|
|
CN1562050A
(zh)
|
2004-03-24 |
2005-01-12 |
中国海洋大学 |
褐藻酸寡糖在抗痴呆、抗糖尿病中的应用
|
|
WO2005095633A1
(en)
|
2004-04-02 |
2005-10-13 |
Queen's University At Kingston |
A cell culture system for modelling serum amyloid a amyloidogenesis and identifying amyloid modulating compounds
|
|
TW200635607A
(en)
|
2004-12-15 |
2006-10-16 |
Elan Pharm Inc |
Humanized Aβ antibodies for use in improving cognition
|
|
WO2006066049A2
(en)
|
2004-12-15 |
2006-06-22 |
Neuralab Limited |
Humanized antibodies that recognize beta amyloid peptide
|
|
EP1676859A1
(en)
|
2004-12-30 |
2006-07-05 |
Pevion Biotech Ltd. |
Immunogenic compositions of cyclic peptides derived from the beta-amyloid peptide
|
|
ES2259270B1
(es)
|
2005-03-09 |
2007-11-01 |
Consejo Superior De Investigaciones Cientificas |
Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal.
|
|
AU2006251832A1
(en)
|
2005-05-27 |
2006-11-30 |
Queen's University At Kingston |
Treatment of protein folding disorders
|
|
KR20080095836A
(ko)
|
2005-11-10 |
2008-10-29 |
로스캄프 리서치 엘엘씨 |
Ａ―베타 펩티드 단편에 의한 혈관형성의 조정
|
|
AR057233A1
(es)
|
2005-12-12 |
2007-11-21 |
Hoffmann La Roche |
Glicosilacion en la region variable
|
|
US8784810B2
(en)
|
2006-04-18 |
2014-07-22 |
Janssen Alzheimer Immunotherapy |
Treatment of amyloidogenic diseases
|
|
SI2074145T1
(sl)
|
2006-10-02 |
2017-12-29 |
Ac Immune S.A. |
Humanizirano protitelo proti amiloid beta
|
|
KR101160385B1
(ko)
|
2007-01-18 |
2012-07-10 |
일라이 릴리 앤드 캄파니 |
페길화된 Ａβ ＦＡＢ
|
|
US8003097B2
(en)
|
2007-04-18 |
2011-08-23 |
Janssen Alzheimer Immunotherapy |
Treatment of cerebral amyloid angiopathy
|
|
PL2170389T3
(pl)
|
2007-06-12 |
2015-03-31 |
Ac Immune Sa |
Humanizowane przeciwciało przeciw amyloidowi beta
|
|
AR066987A1
(es)
|
2007-06-12 |
2009-09-23 |
Ac Immune Sa |
Anticuerpo monoclonal contra proteina beta-amiloide
|
|
DK2182983T3
(da)
|
2007-07-27 |
2014-07-14 |
Janssen Alzheimer Immunotherap |
Behandling af amyloidogene sygdomme med humaniserede anti-abeta antistoffer
|
|
RU2571859C2
(ru)
|
2007-10-05 |
2015-12-20 |
Дженентек, Инк. |
Применение антитела против амилоида-бета при глазных заболеваниях
|
|
CN105169388A
(zh)
|
2007-10-05 |
2015-12-23 |
基因技术公司 |
人源化抗体
|
|
US20090246191A1
(en)
|
2007-10-11 |
2009-10-01 |
University Of Tennessee Research Foundation |
Preparation of Purified Covalently Cross-linked Abeta Oligomers and Uses Thereof
|
|
JO3076B1
(ar)
|
2007-10-17 |
2017-03-15 |
Janssen Alzheimer Immunotherap |
نظم العلاج المناعي المعتمد على حالة apoe
|
|
MX2010004660A
(es)
|
2007-10-29 |
2010-07-30 |
Inserm Inst Nat De La Sante De |
NUEVOS ANTICUERPOS ESPECIFICOS DE LOS PEPTIDOS ß-AMILOIDES Y SUS USOS COMO AGENTES DE DIAGNOSTICO Y DROGAS.
|
|
KR101581733B1
(ko)
|
2007-11-16 |
2015-12-31 |
더 락커펠러 유니버시티 |
원섬유 형태의 베타아밀로이드 단백질에 대해 특이적인 항체
|
|
MX384227B
(es)
|
2007-12-28 |
2025-03-14 |
Univ Tennessee Res Found |
Anticuerpos y fragmentos de unión a antígenos para usarse en el tratamiento y la profilaxis de amiloidosis.
|
|
WO2009143489A2
(en)
|
2008-05-22 |
2009-11-26 |
Archer Pharmaceuticals, Inc. |
Modulation of angiogenesis by a-beta peptide fragments
|
|
AT509611B1
(de)
|
2008-06-12 |
2012-04-15 |
Affiris Forschungs-Und Entwicklungs Gmbh |
Vakzin
|
|
CA2723995A1
(en)
|
2008-06-12 |
2009-12-17 |
Affiris Ag |
Compounds for treating symptoms associated with parkinson's disease
|
|
AT506819B1
(de)
|
2008-06-12 |
2011-06-15 |
Affiris Forschungs Und Entwicklungs Gmbh |
Vakzin zur behandlung von alzheimer-krankheit
|
|
AU2009266552B2
(en)
|
2008-07-01 |
2014-01-23 |
De Staat Der Nederlanden, Vert. Door De Minister Van Vws |
Vaccine against amyloid folding intermediate
|
|
US9801865B2
(en)
|
2008-09-24 |
2017-10-31 |
The United States Of America As Represented By The Department Of Veteran Affairs |
Materials and methods for diagnosis, prevention and/or treatment of stress disorders and conditions associated with abeta peptide aggregation
|
|
EP2342220B1
(en)
|
2008-10-06 |
2021-05-12 |
The University Of British Columbia |
Methods and systems for predicting misfolded protein epitopes
|
|
US9067981B1
(en)
|
2008-10-30 |
2015-06-30 |
Janssen Sciences Ireland Uc |
Hybrid amyloid-beta antibodies
|
|
US9090679B2
(en)
*
|
2009-04-17 |
2015-07-28 |
Immunas Pharma, Inc. |
Antibodies that specifically bind to A beta oligomers and use thereof
|
|
WO2010128139A1
(en)
|
2009-05-08 |
2010-11-11 |
Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin |
Biomarkers and methods for diagnosing alzheimer's disease and/ or mild cognitive impairment
|
|
DK2462161T3
(en)
|
2009-08-06 |
2017-06-06 |
Immunas Pharma Inc |
Antibodies specifically binding to A-beta oligomers and their use
|
|
WO2011016568A1
(ja)
*
|
2009-08-07 |
2011-02-10 |
協和発酵キリン株式会社 |
抗アミロイドβオリゴマーヒト化抗体
|
|
JP2013505438A
(ja)
|
2009-09-18 |
2013-02-14 |
プロビオドルグ エージー |
アミロイドβペプチドの検出のための新規アッセイ
|
|
RU2555526C2
(ru)
|
2010-02-26 |
2015-07-10 |
Байоарктик Ньюросайенс Аб |
Антитела, связывающиеся с протофибриллами, и их применение в методах терапии и диагностики болезни паркинсона, деменции, ассоциированной с образованием диффузных телец леви, и других альфа-синуклеинопатий
|
|
US9216217B2
(en)
|
2010-03-03 |
2015-12-22 |
The University Of British Columbia |
Oligomer-specific amyloid beta epitope and antibodies
|
|
EP2377860A1
(en)
|
2010-04-16 |
2011-10-19 |
AC Immune S.A. |
Novel compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
|
|
DK2558446T5
(da)
|
2010-04-16 |
2019-12-09 |
Ac Immune Sa |
Nye forbindelser til behandling af sygdomme associerede med amyloid- eller amyloidlignende proteiner
|
|
EP3533803B1
(en)
*
|
2010-08-14 |
2021-10-27 |
AbbVie Inc. |
Anti-amyloid-beta antibodies
|
|
WO2012051498A2
(en)
|
2010-10-15 |
2012-04-19 |
The Board Of Regents Of The University Of Texas System |
Antibodies that bind amyloid oligomers
|
|
FR2966827B1
(fr)
|
2010-10-27 |
2014-08-22 |
Kimonella Ventures Ltd |
Compose peptidique utile pour l'inhibition de la formation de plaques amyloides
|
|
US20120321694A1
(en)
|
2010-10-27 |
2012-12-20 |
Daniel Larocque |
Compositions and uses
|
|
WO2012104824A1
(en)
|
2011-02-04 |
2012-08-09 |
Ecole polytechnique fédérale de Lausanne (EPFL) |
Therapeutic antibodies targeting app-c99
|
|
EP2511296A1
(en)
|
2011-04-12 |
2012-10-17 |
Araclón Biotech, S. L. |
Antibody, kit and method for determination of amyloid peptides
|
|
GB201113570D0
(en)
|
2011-08-05 |
2011-09-21 |
Glaxosmithkline Biolog Sa |
Vaccine
|
|
AU2012335014A1
(en)
|
2011-11-10 |
2014-06-19 |
Cangene U.S., Incorporated |
Compositions and methods for treating Alzheimer's disease
|
|
EP2659908A1
(en)
|
2012-05-01 |
2013-11-06 |
Affiris AG |
Compositions
|
|
WO2014031697A2
(en)
|
2012-08-21 |
2014-02-27 |
The Institute Of Molecular Medicine |
COMPOSITIONS AND METHODS RELATED TO DISEASES ASSOCIATED WITH DEPOSITS OF AMYLOID, TAU, AND α-SYNUCLEIN
|
|
EP2787347A1
(en)
|
2013-04-03 |
2014-10-08 |
Affiris AG |
Method for detecting Aß-specific antibodies in a biological sample
|
|
AU2014305658A1
(en)
|
2013-08-05 |
2016-02-11 |
St. Vincent's Institute Of Medical Research |
An antibody therapy for amyloid beta disease
|
|
BR112016004242A8
(pt)
*
|
2013-08-28 |
2018-06-12 |
Stemcentrx Inc |
Métodos para conjugação sítio-específica de anticorpos e composições
|
|
EP3102611A4
(en)
|
2014-02-03 |
2017-08-23 |
Cangene Corporation |
Humanized beta-amyloid binding molecules and uses thereof
|
|
WO2016138525A1
(en)
*
|
2015-02-27 |
2016-09-01 |
University Of Washington |
Polypeptide assemblies and methods for the production thereof
|
|
US20170021020A1
(en)
|
2015-07-23 |
2017-01-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Monoclonal antibody and vaccine targeting filamentous bacteriophage
|
|
SG10202111808WA
(en)
|
2015-08-11 |
2021-11-29 |
Novartis Ag |
5-bromo-2,6-di-(1h-pyrazol-1-yl)pyrimidin-4-amine for use in the treatment of cancer
|
|
AU2016354688B2
(en)
*
|
2015-11-09 |
2021-12-16 |
The University Of British Columbia |
Epitopes in Amyloid beta mid-region and conformationally-selective antibodies thereto
|
|
JP2019507581A
(ja)
|
2015-11-09 |
2019-03-22 |
ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア |
アミロイドベータのエピトープおよびそれに対する立体配座選択的抗体
|
|
EP3374379A4
(en)
|
2015-11-09 |
2019-05-15 |
The University Of British Columbia |
N-TERMINAL EPITOPES IN AMYLOID BETA AND CONFORMATION-SELECTIVE ANTIBODIES
|
|
HK1259324A1
(zh)
|
2015-11-09 |
2019-11-29 |
英属哥伦比亚大学 |
淀粉样蛋白β表位及其抗体
|
|
US11756650B2
(en)
*
|
2015-11-09 |
2023-09-12 |
The University Of British Columbia |
Systems and methods for predicting misfolded protein epitopes by collective coordinate biasing
|
|
CN108368160A
(zh)
|
2015-11-09 |
2018-08-03 |
英属哥伦比亚大学 |
淀粉样蛋白β中的C-末端表位及其构象选择性抗体
|
|
KR102550991B1
(ko)
|
2016-07-18 |
2023-07-04 |
더 유니버시티 오브 브리티쉬 콜롬비아 |
아밀로이드 베타에 대한 항체
|
|
US20180125920A1
(en)
*
|
2016-11-09 |
2018-05-10 |
The University Of British Columbia |
Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions
|