JP2019528769A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019528769A5 JP2019528769A5 JP2019518049A JP2019518049A JP2019528769A5 JP 2019528769 A5 JP2019528769 A5 JP 2019528769A5 JP 2019518049 A JP2019518049 A JP 2019518049A JP 2019518049 A JP2019518049 A JP 2019518049A JP 2019528769 A5 JP2019528769 A5 JP 2019528769A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- human
- cell
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108020004707 nucleic acids Proteins 0.000 claims 19
- 150000007523 nucleic acids Chemical class 0.000 claims 19
- 102000039446 nucleic acids Human genes 0.000 claims 19
- 210000001744 T-lymphocyte Anatomy 0.000 claims 13
- 108010019670 Chimeric Antigen Receptors Proteins 0.000 claims 9
- 239000013603 viral vector Substances 0.000 claims 8
- 101710163270 Nuclease Proteins 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 108020004511 Recombinant DNA Proteins 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 238000003776 cleavage reaction Methods 0.000 claims 4
- 230000007017 scission Effects 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 3
- 239000013607 AAV vector Substances 0.000 claims 2
- 108010017070 Zinc Finger Nucleases Proteins 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 208000032839 leukemia Diseases 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 201000009410 rhabdomyosarcoma Diseases 0.000 claims 2
- 102100024222 B-lymphocyte antigen CD19 Human genes 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 108091033409 CRISPR Proteins 0.000 claims 1
- 238000010354 CRISPR gene editing Methods 0.000 claims 1
- 201000009030 Carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 241000702421 Dependoparvovirus Species 0.000 claims 1
- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 206010029260 Neuroblastoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 206010039491 Sarcoma Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 201000000053 blastoma Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 230000000139 costimulatory effect Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 201000008184 embryoma Diseases 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 230000006801 homologous recombination Effects 0.000 claims 1
- 238000002744 homologous recombination Methods 0.000 claims 1
- 230000001024 immunotherapeutic effect Effects 0.000 claims 1
- 230000004068 intracellular signaling Effects 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 201000008968 osteosarcoma Diseases 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 108091006106 transcriptional activators Proteins 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021083808A JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2022112159A JP2022160443A (ja) | 2016-10-04 | 2022-07-13 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2024013162A JP2024059633A (ja) | 2016-10-04 | 2024-01-31 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662403880P | 2016-10-04 | 2016-10-04 | |
| US62/403,880 | 2016-10-04 | ||
| US201762501475P | 2017-05-04 | 2017-05-04 | |
| US62/501,475 | 2017-05-04 | ||
| US201762556199P | 2017-09-08 | 2017-09-08 | |
| US62/556,199 | 2017-09-08 | ||
| PCT/US2017/055133 WO2018067697A1 (en) | 2016-10-04 | 2017-10-04 | Co-stimulatory domains for use in genetically-modified cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021083808A Division JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2019528769A JP2019528769A (ja) | 2019-10-17 |
| JP2019528769A5 true JP2019528769A5 (cg-RX-API-DMAC7.html) | 2020-11-12 |
| JP6887492B2 JP6887492B2 (ja) | 2021-06-16 |
| JP6887492B6 JP6887492B6 (ja) | 2021-07-14 |
Family
ID=60382586
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019518049A Active JP6887492B6 (ja) | 2016-10-04 | 2017-10-04 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2021083808A Active JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2022112159A Pending JP2022160443A (ja) | 2016-10-04 | 2022-07-13 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2024013162A Pending JP2024059633A (ja) | 2016-10-04 | 2024-01-31 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021083808A Active JP7106715B2 (ja) | 2016-10-04 | 2021-05-18 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2022112159A Pending JP2022160443A (ja) | 2016-10-04 | 2022-07-13 | 遺伝子改変細胞で使用するための共刺激ドメイン |
| JP2024013162A Pending JP2024059633A (ja) | 2016-10-04 | 2024-01-31 | 遺伝子改変細胞で使用するための共刺激ドメイン |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US11286291B2 (cg-RX-API-DMAC7.html) |
| EP (3) | EP3523326B1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP6887492B6 (cg-RX-API-DMAC7.html) |
| AU (4) | AU2017338846B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3039014A1 (cg-RX-API-DMAC7.html) |
| DK (2) | DK3757120T3 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2811500T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018067697A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ739448A (en) | 2014-04-10 | 2019-10-25 | Seattle Children’S Hospital Dba Seattle Children’S Res Institute | Transgene genetic tags and methods of use |
| WO2017027291A1 (en) | 2015-08-07 | 2017-02-16 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Bispecific car t-cells for solid tumor targeting |
| ES2811500T3 (es) * | 2016-10-04 | 2021-03-12 | Prec Biosciences Inc | Dominios coestimuladores para su uso en células genéticamente modificadas |
| WO2018102785A2 (en) | 2016-12-03 | 2018-06-07 | Juno Therapeutics, Inc. | Methods and compositions for use of therapeutic t cells in combination with kinase inhibitors |
| EP3615662A1 (en) * | 2017-04-28 | 2020-03-04 | Precision Biosciences, Inc. | Methods for reducing dna-induced cytotoxicity and enhancing gene editing in primary cells |
| US11413310B2 (en) | 2017-06-02 | 2022-08-16 | Juno Therapeutics, Inc. | Articles of manufacture and methods for treatment using adoptive cell therapy |
| US11434290B2 (en) * | 2017-06-08 | 2022-09-06 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Chimeric antigen receptors with enhanced NFκB signaling |
| US10869888B2 (en) | 2018-04-17 | 2020-12-22 | Innovative Cellular Therapeutics CO., LTD. | Modified cell expansion and uses thereof |
| US12240915B2 (en) | 2018-08-30 | 2025-03-04 | Innovative Cellular Therapeutics Holdings, Ltd. | Chimeric antigen receptor cells for treating solid tumor |
| US10918667B2 (en) | 2018-11-20 | 2021-02-16 | Innovative Cellular Therapeutics CO., LTD. | Modified cell expressing therapeutic agent and uses thereof |
| KR20240122580A (ko) | 2019-04-03 | 2024-08-12 | 프리시젼 바이오사이언시스 인코포레이티드 | 마이크로RNA-적응 shRNA(shRNAmiR)를 포함하는 유전자-변형 면역 세포 |
| CA3136265A1 (en) | 2019-04-05 | 2020-10-08 | Precision Biosciences, Inc. | Methods of preparing populations of genetically-modified immune cells |
| EP4004216A1 (en) | 2019-07-25 | 2022-06-01 | Precision BioSciences, Inc. | Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus |
| CA3148179A1 (en) | 2019-08-20 | 2021-02-25 | Bruce J. Mccreedy Jr. | Lymphodepletion dosing regimens for cellular immunotherapies |
| US20220411479A1 (en) | 2019-10-30 | 2022-12-29 | Precision Biosciences, Inc. | Cd20 chimeric antigen receptors and methods of use for immunotherapy |
| CA3160096A1 (en) | 2019-12-06 | 2021-06-10 | Bruce J. Mccreedy Jr. | Methods for cancer immunotherapy |
| AU2021219885B2 (en) * | 2020-02-13 | 2025-07-24 | Beijing Immunochina Pharmaceuticals Co., Ltd. | Optimization of chimeric antigen receptor |
| US12076343B2 (en) | 2020-02-19 | 2024-09-03 | Innovative Cellular Therapeutics Holdings, Ltd. | Engineered safety in cell therapy |
| WO2021231954A1 (en) * | 2020-05-15 | 2021-11-18 | Precision Biosciences, Inc. | Methods for immunotherapy |
| US20230192807A1 (en) * | 2020-05-15 | 2023-06-22 | Precision Biosciences, Inc. | Methods for immunotherapy |
| US12043654B2 (en) | 2020-06-02 | 2024-07-23 | Innovative Cellular Therapeutics Holdings, Ltd. | Anti-GCC antibody and CAR thereof for treating digestive system cancer |
| AU2021300615A1 (en) * | 2020-06-30 | 2023-02-02 | The University Court Of The University Of Edinburgh | Transgene expression system |
| WO2022035793A1 (en) | 2020-08-10 | 2022-02-17 | Precision Biosciences, Inc. | Antibodies and fragments specific for b-cell maturation antigen and uses thereof |
| US20230365995A1 (en) | 2020-10-07 | 2023-11-16 | Precision Biosciences, Inc. | Lipid nanoparticle compositions |
| US20250127811A1 (en) | 2021-01-28 | 2025-04-24 | Precision Biosciences, Inc. | Modulation of tgf beta signaling in genetically-modified eukaryotic cells |
| WO2022266192A1 (en) * | 2021-06-16 | 2022-12-22 | Instil Bio, Inc. | Receptors providing targeted costimulation for adoptive cell therapy |
| WO2023064872A1 (en) | 2021-10-14 | 2023-04-20 | Precision Biosciences, Inc. | Combinations of anti-bcma car t cells and gamma secretase inhibitors |
| WO2023081767A1 (en) | 2021-11-05 | 2023-05-11 | Precision Biosciences, Inc. | Methods for immunotherapy |
| US20250009800A1 (en) | 2021-11-16 | 2025-01-09 | Precision Biosciences, Inc. | Methods for cancer immunotherapy |
| US20250041417A1 (en) | 2021-12-10 | 2025-02-06 | Precision Biosciences, Inc. | Methods for cancer immunotherapy |
| JP2025503546A (ja) | 2021-12-30 | 2025-02-04 | ティーアール１エックス，インコーポレーテッド | Ｉｌ－１０およびキメラ抗原受容体を発現するｃｄ４＋ｔ細胞およびその使用 |
| EP4646223A1 (en) | 2023-01-05 | 2025-11-12 | Precision Biosciences, Inc. | Optimized engineered meganucleases having specificity for the human t cell receptor alpha constant region gene |
Family Cites Families (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873192A (en) | 1987-02-17 | 1989-10-10 | The United States Of America As Represented By The Department Of Health And Human Services | Process for site specific mutagenesis without phenotypic selection |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| AU704601B2 (en) | 1994-01-18 | 1999-04-29 | Scripps Research Institute, The | Zinc finger protein derivatives and methods therefor |
| US6140466A (en) | 1994-01-18 | 2000-10-31 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
| USRE39229E1 (en) | 1994-08-20 | 2006-08-08 | Gendaq Limited | Binding proteins for recognition of DNA |
| GB9824544D0 (en) | 1998-11-09 | 1999-01-06 | Medical Res Council | Screening system |
| US5789538A (en) | 1995-02-03 | 1998-08-04 | Massachusetts Institute Of Technology | Zinc finger proteins with high affinity new DNA binding specificities |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| US5925523A (en) | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| US6015832A (en) | 1997-12-31 | 2000-01-18 | The Regents Of The University Of Michigan | Methods of inactivating bacteria including bacterial spores |
| US6559189B2 (en) | 1999-04-28 | 2003-05-06 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
| US6506803B1 (en) | 1999-04-28 | 2003-01-14 | Regents Of The University Of Michigan | Methods of preventing and treating microbial infections |
| US7767216B2 (en) | 1999-04-28 | 2010-08-03 | The Regents Of The University Of Michigan | Antimicrobial compositions and methods of use |
| US6635676B2 (en) | 1999-04-28 | 2003-10-21 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
| JP2003516124A (ja) | 1999-10-15 | 2003-05-13 | ユニバーシティー オブ マサチューセッツ | 標的とした遺伝的干渉の手段としてのｒｎａ干渉経路遺伝子 |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| US20020061512A1 (en) | 2000-02-18 | 2002-05-23 | Kim Jin-Soo | Zinc finger domains and methods of identifying same |
| WO2001088197A2 (en) | 2000-05-16 | 2001-11-22 | Massachusetts Institute Of Technology | Methods and compositions for interaction trap assays |
| AU2001275474A1 (en) | 2000-06-12 | 2001-12-24 | Akkadix Corporation | Materials and methods for the control of nematodes |
| US6555674B2 (en) | 2000-08-09 | 2003-04-29 | Nsgene A/S | JeT promoter |
| GB0108491D0 (en) | 2001-04-04 | 2001-05-23 | Gendaq Ltd | Engineering zinc fingers |
| JP4968498B2 (ja) | 2002-01-23 | 2012-07-04 | ユニバーシティ オブ ユタ リサーチ ファウンデーション | ジンクフィンガーヌクレアーゼを用いる、標的化された染色体変異誘発 |
| EP2368982A3 (en) | 2002-03-21 | 2011-10-12 | Sangamo BioSciences, Inc. | Methods and compositions for using zinc finger endonucleases to enhance homologous recombination |
| US9447434B2 (en) | 2002-09-05 | 2016-09-20 | California Institute Of Technology | Use of chimeric nucleases to stimulate gene targeting |
| US8409861B2 (en) | 2003-08-08 | 2013-04-02 | Sangamo Biosciences, Inc. | Targeted deletion of cellular DNA sequences |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7435596B2 (en) | 2004-11-04 | 2008-10-14 | St. Jude Children's Research Hospital, Inc. | Modified cell line and method for expansion of NK cell |
| US20130266551A1 (en) | 2003-11-05 | 2013-10-10 | St. Jude Children's Research Hospital, Inc. | Chimeric receptors with 4-1bb stimulatory signaling domain |
| SG10201508995QA (en) | 2005-07-26 | 2015-11-27 | Sangamo Biosciences Inc | Targeted integration and expression of exogenous nucleic acid sequences |
| ES2533370T3 (es) | 2005-10-18 | 2015-04-09 | Precision Biosciences | Meganucleasas diseñadas racionalmente con especificidad de secuencia y afinidad de unión a ADN alteradas |
| EP2660317B1 (en) | 2007-10-31 | 2016-04-06 | Precision Biosciences, Inc. | Rationally-designed single-chain meganucleases with non-palindromic recognition sequences |
| EP2206723A1 (en) | 2009-01-12 | 2010-07-14 | Bonas, Ulla | Modular DNA-binding domains |
| US8465743B2 (en) * | 2009-10-01 | 2013-06-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer |
| WO2011072246A2 (en) | 2009-12-10 | 2011-06-16 | Regents Of The University Of Minnesota | Tal effector-mediated dna modification |
| EP3320910A1 (en) | 2011-04-05 | 2018-05-16 | Cellectis | Method for the generation of compact tale-nucleases and uses thereof |
| US9272002B2 (en) * | 2011-10-28 | 2016-03-01 | The Trustees Of The University Of Pennsylvania | Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| PL3300745T3 (pl) * | 2013-02-15 | 2020-03-31 | The Regents Of The University Of California | Chimeryczny receptor antygenowy i sposoby jego zastosowania |
| CN106132423B (zh) | 2014-02-14 | 2020-07-31 | 贝里坤制药股份有限公司 | 用诱导型嵌合多肽活化t细胞的方法 |
| CA2949325A1 (en) | 2014-06-17 | 2015-12-23 | Cellectis | Cd123 specific multi-chain chimeric antigen receptor |
| EP3171882A1 (en) * | 2014-07-21 | 2017-05-31 | Novartis AG | Treatment of cancer using a cll-1 chimeric antigen receptor |
| JP2017522884A (ja) * | 2014-07-29 | 2017-08-17 | ファイザー・インク | がん免疫療法のためのＥＧＦＲｖＩＩＩ特異的キメラ抗原受容体 |
| EP3189148A4 (en) | 2014-09-02 | 2018-05-02 | Bellicum Pharmaceuticals, Inc. | Costimulation of chimeric antigen receptors by myd88 and cd40 polypeptides |
| CA2963327A1 (en) | 2014-10-07 | 2016-04-14 | Cellectis | Method for modulating car-induced immune cells activity |
| WO2016090190A1 (en) * | 2014-12-03 | 2016-06-09 | Juno Therapeutics, Inc. | Methods and compositions for adoptive cell therapy |
| IL252295B2 (en) | 2014-12-19 | 2023-10-01 | Dana Farber Cancer Inst Inc | Chimeric antigen receptors and methods of using them |
| CA2973529A1 (en) * | 2015-01-26 | 2016-08-04 | Cellectis | Cll1-specific multi-chain chimeric antigen receptor |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| ES2811500T3 (es) * | 2016-10-04 | 2021-03-12 | Prec Biosciences Inc | Dominios coestimuladores para su uso en células genéticamente modificadas |
| KR20240122580A (ko) * | 2019-04-03 | 2024-08-12 | 프리시젼 바이오사이언시스 인코포레이티드 | 마이크로RNA-적응 shRNA(shRNAmiR)를 포함하는 유전자-변형 면역 세포 |
| US20220411479A1 (en) * | 2019-10-30 | 2022-12-29 | Precision Biosciences, Inc. | Cd20 chimeric antigen receptors and methods of use for immunotherapy |
| CA3160096A1 (en) * | 2019-12-06 | 2021-06-10 | Bruce J. Mccreedy Jr. | Methods for cancer immunotherapy |
-
2017
- 2017-10-04 ES ES17800638T patent/ES2811500T3/es active Active
- 2017-10-04 US US16/339,699 patent/US11286291B2/en active Active
- 2017-10-04 DK DK20176441.2T patent/DK3757120T3/da active
- 2017-10-04 ES ES20176441T patent/ES2925644T3/es active Active
- 2017-10-04 JP JP2019518049A patent/JP6887492B6/ja active Active
- 2017-10-04 EP EP17800638.3A patent/EP3523326B1/en active Active
- 2017-10-04 WO PCT/US2017/055133 patent/WO2018067697A1/en not_active Ceased
- 2017-10-04 CA CA3039014A patent/CA3039014A1/en active Pending
- 2017-10-04 EP EP22172338.0A patent/EP4115951A1/en active Pending
- 2017-10-04 DK DK17800638.3T patent/DK3523326T3/da active
- 2017-10-04 EP EP20176441.2A patent/EP3757120B8/en active Active
- 2017-10-04 AU AU2017338846A patent/AU2017338846B2/en active Active
-
2019
- 2019-10-11 US US16/600,074 patent/US10800833B2/en active Active
-
2020
- 2020-09-09 US US17/016,016 patent/US20200399346A1/en not_active Abandoned
- 2020-12-11 AU AU2020286323A patent/AU2020286323B2/en active Active
-
2021
- 2021-05-18 JP JP2021083808A patent/JP7106715B2/ja active Active
-
2022
- 2022-07-13 JP JP2022112159A patent/JP2022160443A/ja active Pending
-
2023
- 2023-05-10 AU AU2023202905A patent/AU2023202905A1/en not_active Abandoned
- 2023-08-21 US US18/453,022 patent/US20240018215A1/en active Pending
-
2024
- 2024-01-31 JP JP2024013162A patent/JP2024059633A/ja active Pending
-
2025
- 2025-02-03 AU AU2025200717A patent/AU2025200717A1/en active Pending