JP2019527225A5 - - Google Patents
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- Publication number
- JP2019527225A5 JP2019527225A5 JP2019503232A JP2019503232A JP2019527225A5 JP 2019527225 A5 JP2019527225 A5 JP 2019527225A5 JP 2019503232 A JP2019503232 A JP 2019503232A JP 2019503232 A JP2019503232 A JP 2019503232A JP 2019527225 A5 JP2019527225 A5 JP 2019527225A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- radiolabeled compound
- composition
- ido1
- radiolabeled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 23
- 239000000203 mixture Substances 0.000 claims 12
- 101001037256 Homo sapiens Indoleamine 2,3-dioxygenase 1 Proteins 0.000 claims 11
- 102100040061 Indoleamine 2,3-dioxygenase 1 Human genes 0.000 claims 11
- 239000012216 imaging agent Substances 0.000 claims 6
- 238000002600 positron emission tomography Methods 0.000 claims 6
- 238000001727 in vivo Methods 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 238000003384 imaging method Methods 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229940043367 IDO1 inhibitor Drugs 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000011503 in vivo imaging Methods 0.000 claims 1
- 230000004807 localization Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662364020P | 2016-07-19 | 2016-07-19 | |
| US62/364,020 | 2016-07-19 | ||
| PCT/US2017/042510 WO2018017529A1 (en) | 2016-07-19 | 2017-07-18 | Radioligands for imaging the ido1 enzyme |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019527225A JP2019527225A (ja) | 2019-09-26 |
| JP2019527225A5 true JP2019527225A5 (https=) | 2020-08-20 |
| JP6987840B2 JP6987840B2 (ja) | 2022-01-05 |
Family
ID=59416832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503232A Active JP6987840B2 (ja) | 2016-07-19 | 2017-07-18 | Ｉｄｏ１酵素イメージングのための放射性リガンド |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20190282714A1 (https=) |
| EP (1) | EP3487516A1 (https=) |
| JP (1) | JP6987840B2 (https=) |
| KR (1) | KR102513886B1 (https=) |
| CN (1) | CN109475594A (https=) |
| AU (1) | AU2017298262B2 (https=) |
| BR (1) | BR112019000499A2 (https=) |
| EA (1) | EA039877B1 (https=) |
| IL (1) | IL264187B (https=) |
| MX (1) | MX2019000508A (https=) |
| SG (1) | SG11201900336YA (https=) |
| WO (1) | WO2018017529A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018039518A1 (en) * | 2016-08-26 | 2018-03-01 | Bristol-Myers Squibb Company | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use |
| EP3645008A4 (en) * | 2017-06-30 | 2020-12-09 | Bristol-Myers Squibb Company | SUBSTITUTED QUINOLINYCYCLOHEXYLPROPANAMIDE COMPOUNDS AND IMPROVED METHODS FOR THEIR PRODUCTION |
| EP3993507A1 (en) * | 2017-11-21 | 2022-05-04 | Guangdong Oppo Mobile Telecommunications Corp., Ltd. | Information transmission method, network device, and terminal device |
| BR112020010964A2 (pt) * | 2017-12-05 | 2020-11-17 | Glaxosmithkline Intellectual Property Development Limited | moduladores da indolamina 2,3-dioxigenase |
| CN110357813A (zh) * | 2018-04-09 | 2019-10-22 | 信达生物制药(苏州)有限公司 | 一种新型吲哚胺2,3-双加氧酶抑制剂及其制备方法和用途 |
| AR120935A1 (es) * | 2020-01-02 | 2022-03-30 | Hutchison Medipharma Ltd | Derivados de amida y usos de los mismos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101182359A (zh) * | 2007-11-09 | 2008-05-21 | 中山大学 | 人吲哚胺2,3-双加氧酶多克隆抗体及其制备方法和应用 |
| AU2011223883B2 (en) * | 2010-03-01 | 2015-10-08 | Cavion, Inc. | Cancer diagnosis and imaging |
| WO2016040458A2 (en) * | 2014-09-09 | 2016-03-17 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Pet probes of radiofluorinated carboximidamides for ido-targeted imaging |
| UY36390A (es) * | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
-
2017
- 2017-07-18 EP EP17745597.9A patent/EP3487516A1/en active Pending
- 2017-07-18 CN CN201780044908.4A patent/CN109475594A/zh active Pending
- 2017-07-18 MX MX2019000508A patent/MX2019000508A/es unknown
- 2017-07-18 SG SG11201900336YA patent/SG11201900336YA/en unknown
- 2017-07-18 WO PCT/US2017/042510 patent/WO2018017529A1/en not_active Ceased
- 2017-07-18 US US16/318,209 patent/US20190282714A1/en not_active Abandoned
- 2017-07-18 JP JP2019503232A patent/JP6987840B2/ja active Active
- 2017-07-18 EA EA201990198A patent/EA039877B1/ru unknown
- 2017-07-18 KR KR1020197004720A patent/KR102513886B1/ko active Active
- 2017-07-18 AU AU2017298262A patent/AU2017298262B2/en active Active
- 2017-07-18 BR BR112019000499-8A patent/BR112019000499A2/pt unknown
-
2019
- 2019-01-10 IL IL264187A patent/IL264187B/en active IP Right Grant
-
2022
- 2022-04-18 US US17/722,628 patent/US20220305144A1/en not_active Abandoned
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