JP2019527225A5 - - Google Patents
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- Publication number
- JP2019527225A5 JP2019527225A5 JP2019503232A JP2019503232A JP2019527225A5 JP 2019527225 A5 JP2019527225 A5 JP 2019527225A5 JP 2019503232 A JP2019503232 A JP 2019503232A JP 2019503232 A JP2019503232 A JP 2019503232A JP 2019527225 A5 JP2019527225 A5 JP 2019527225A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- radiolabeled compound
- composition
- ido1
- radiolabeled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 23
- 239000000203 mixture Substances 0.000 claims 12
- 101001037256 Homo sapiens Indoleamine 2,3-dioxygenase 1 Proteins 0.000 claims 11
- 102100040061 Indoleamine 2,3-dioxygenase 1 Human genes 0.000 claims 11
- 239000012216 imaging agent Substances 0.000 claims 6
- 238000002600 positron emission tomography Methods 0.000 claims 6
- 238000001727 in vivo Methods 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 238000003384 imaging method Methods 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 229940043367 IDO1 inhibitor Drugs 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000011503 in vivo imaging Methods 0.000 claims 1
- 230000004807 localization Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662364020P | 2016-07-19 | 2016-07-19 | |
| US62/364,020 | 2016-07-19 | ||
| PCT/US2017/042510 WO2018017529A1 (en) | 2016-07-19 | 2017-07-18 | Radioligands for imaging the ido1 enzyme |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019527225A JP2019527225A (ja) | 2019-09-26 |
| JP2019527225A5 true JP2019527225A5 (https=) | 2020-08-20 |
| JP6987840B2 JP6987840B2 (ja) | 2022-01-05 |
Family
ID=59416832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019503232A Active JP6987840B2 (ja) | 2016-07-19 | 2017-07-18 | Ｉｄｏ１酵素イメージングのための放射性リガンド |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20190282714A1 (https=) |
| EP (1) | EP3487516A1 (https=) |
| JP (1) | JP6987840B2 (https=) |
| KR (1) | KR102513886B1 (https=) |
| CN (1) | CN109475594A (https=) |
| AU (1) | AU2017298262B2 (https=) |
| BR (1) | BR112019000499A2 (https=) |
| EA (1) | EA039877B1 (https=) |
| IL (1) | IL264187B (https=) |
| MX (1) | MX2019000508A (https=) |
| SG (1) | SG11201900336YA (https=) |
| WO (1) | WO2018017529A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11351164B2 (en) * | 2016-08-26 | 2022-06-07 | Bristol-Myers Squibb Company | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use |
| JP7315483B2 (ja) * | 2017-06-30 | 2023-07-26 | ブリストル－マイヤーズ スクイブ カンパニー | 置換キノリニルシクロヘキシルプロパンアミド化合物および改良されたその製造方法 |
| WO2019100213A1 (zh) * | 2017-11-21 | 2019-05-31 | Oppo广东移动通信有限公司 | 传输信息的方法、网络设备和终端设备 |
| EP3720843A1 (en) * | 2017-12-05 | 2020-10-14 | GlaxoSmithKline Intellectual Property Development Limited | Modulators of indoleamine 2,3-dioxygenase |
| CN110357813A (zh) * | 2018-04-09 | 2019-10-22 | 信达生物制药(苏州)有限公司 | 一种新型吲哚胺2,3-双加氧酶抑制剂及其制备方法和用途 |
| AR120935A1 (es) * | 2020-01-02 | 2022-03-30 | Hutchison Medipharma Ltd | Derivados de amida y usos de los mismos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101182359A (zh) * | 2007-11-09 | 2008-05-21 | 中山大学 | 人吲哚胺2,3-双加氧酶多克隆抗体及其制备方法和应用 |
| EP2542155B1 (en) * | 2010-03-01 | 2015-11-04 | TAU Therapeutics LLC | Method for imaging a disease |
| WO2016040458A2 (en) * | 2014-09-09 | 2016-03-17 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Pet probes of radiofluorinated carboximidamides for ido-targeted imaging |
| UY36390A (es) * | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
-
2017
- 2017-07-18 EP EP17745597.9A patent/EP3487516A1/en active Pending
- 2017-07-18 JP JP2019503232A patent/JP6987840B2/ja active Active
- 2017-07-18 MX MX2019000508A patent/MX2019000508A/es unknown
- 2017-07-18 WO PCT/US2017/042510 patent/WO2018017529A1/en not_active Ceased
- 2017-07-18 SG SG11201900336YA patent/SG11201900336YA/en unknown
- 2017-07-18 KR KR1020197004720A patent/KR102513886B1/ko active Active
- 2017-07-18 BR BR112019000499-8A patent/BR112019000499A2/pt unknown
- 2017-07-18 US US16/318,209 patent/US20190282714A1/en not_active Abandoned
- 2017-07-18 CN CN201780044908.4A patent/CN109475594A/zh active Pending
- 2017-07-18 AU AU2017298262A patent/AU2017298262B2/en active Active
- 2017-07-18 EA EA201990198A patent/EA039877B1/ru unknown
-
2019
- 2019-01-10 IL IL264187A patent/IL264187B/en active IP Right Grant
-
2022
- 2022-04-18 US US17/722,628 patent/US20220305144A1/en not_active Abandoned
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