BR112019000499A2 - radioligantes para imagiologia da enzima ido1 - Google Patents
radioligantes para imagiologia da enzima ido1Info
- Publication number
- BR112019000499A2 BR112019000499A2 BR112019000499-8A BR112019000499A BR112019000499A2 BR 112019000499 A2 BR112019000499 A2 BR 112019000499A2 BR 112019000499 A BR112019000499 A BR 112019000499A BR 112019000499 A2 BR112019000499 A2 BR 112019000499A2
- Authority
- BR
- Brazil
- Prior art keywords
- radioligents
- oxide enzyme
- oxide
- imaging
- enzyme imaging
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/05—Isotopically modified compounds, e.g. labelled
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Quinoline Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662364020P | 2016-07-19 | 2016-07-19 | |
| US62/364,020 | 2016-07-19 | ||
| PCT/US2017/042510 WO2018017529A1 (en) | 2016-07-19 | 2017-07-18 | Radioligands for imaging the ido1 enzyme |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019000499A2 true BR112019000499A2 (pt) | 2019-04-24 |
Family
ID=59416832
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019000499-8A BR112019000499A2 (pt) | 2016-07-19 | 2017-07-18 | radioligantes para imagiologia da enzima ido1 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20190282714A1 (https=) |
| EP (1) | EP3487516A1 (https=) |
| JP (1) | JP6987840B2 (https=) |
| KR (1) | KR102513886B1 (https=) |
| CN (1) | CN109475594A (https=) |
| AU (1) | AU2017298262B2 (https=) |
| BR (1) | BR112019000499A2 (https=) |
| EA (1) | EA039877B1 (https=) |
| IL (1) | IL264187B (https=) |
| MX (1) | MX2019000508A (https=) |
| SG (1) | SG11201900336YA (https=) |
| WO (1) | WO2018017529A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018039518A1 (en) * | 2016-08-26 | 2018-03-01 | Bristol-Myers Squibb Company | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use |
| EP3645008A4 (en) * | 2017-06-30 | 2020-12-09 | Bristol-Myers Squibb Company | SUBSTITUTED QUINOLINYCYCLOHEXYLPROPANAMIDE COMPOUNDS AND IMPROVED METHODS FOR THEIR PRODUCTION |
| EP3993507A1 (en) * | 2017-11-21 | 2022-05-04 | Guangdong Oppo Mobile Telecommunications Corp., Ltd. | Information transmission method, network device, and terminal device |
| BR112020010964A2 (pt) * | 2017-12-05 | 2020-11-17 | Glaxosmithkline Intellectual Property Development Limited | moduladores da indolamina 2,3-dioxigenase |
| CN110357813A (zh) * | 2018-04-09 | 2019-10-22 | 信达生物制药(苏州)有限公司 | 一种新型吲哚胺2,3-双加氧酶抑制剂及其制备方法和用途 |
| AR120935A1 (es) * | 2020-01-02 | 2022-03-30 | Hutchison Medipharma Ltd | Derivados de amida y usos de los mismos |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101182359A (zh) * | 2007-11-09 | 2008-05-21 | 中山大学 | 人吲哚胺2,3-双加氧酶多克隆抗体及其制备方法和应用 |
| AU2011223883B2 (en) * | 2010-03-01 | 2015-10-08 | Cavion, Inc. | Cancer diagnosis and imaging |
| WO2016040458A2 (en) * | 2014-09-09 | 2016-03-17 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Pet probes of radiofluorinated carboximidamides for ido-targeted imaging |
| UY36390A (es) * | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
-
2017
- 2017-07-18 EP EP17745597.9A patent/EP3487516A1/en active Pending
- 2017-07-18 CN CN201780044908.4A patent/CN109475594A/zh active Pending
- 2017-07-18 MX MX2019000508A patent/MX2019000508A/es unknown
- 2017-07-18 SG SG11201900336YA patent/SG11201900336YA/en unknown
- 2017-07-18 WO PCT/US2017/042510 patent/WO2018017529A1/en not_active Ceased
- 2017-07-18 US US16/318,209 patent/US20190282714A1/en not_active Abandoned
- 2017-07-18 JP JP2019503232A patent/JP6987840B2/ja active Active
- 2017-07-18 EA EA201990198A patent/EA039877B1/ru unknown
- 2017-07-18 KR KR1020197004720A patent/KR102513886B1/ko active Active
- 2017-07-18 AU AU2017298262A patent/AU2017298262B2/en active Active
- 2017-07-18 BR BR112019000499-8A patent/BR112019000499A2/pt unknown
-
2019
- 2019-01-10 IL IL264187A patent/IL264187B/en active IP Right Grant
-
2022
- 2022-04-18 US US17/722,628 patent/US20220305144A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017298262B2 (en) | 2024-07-18 |
| MX2019000508A (es) | 2019-03-28 |
| SG11201900336YA (en) | 2019-02-27 |
| EP3487516A1 (en) | 2019-05-29 |
| WO2018017529A1 (en) | 2018-01-25 |
| KR20190030727A (ko) | 2019-03-22 |
| CN109475594A (zh) | 2019-03-15 |
| KR102513886B1 (ko) | 2023-03-27 |
| JP6987840B2 (ja) | 2022-01-05 |
| US20190282714A1 (en) | 2019-09-19 |
| IL264187B (en) | 2021-06-30 |
| US20220305144A1 (en) | 2022-09-29 |
| IL264187A (en) | 2019-02-28 |
| EA201990198A1 (ru) | 2019-06-28 |
| JP2019527225A (ja) | 2019-09-26 |
| CA3031079A1 (en) | 2018-01-25 |
| AU2017298262A1 (en) | 2019-03-07 |
| EA039877B1 (ru) | 2022-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] |