JP2019526595A - 血液癌を治療するための抗ｃｄ２０抗体、ｐｉ３キナーゼ−デルタ阻害剤および抗ｐｄ−１抗体または抗ｐｄ−ｌ１抗体の組み合わせ - Google Patents

血液癌を治療するための抗ｃｄ２０抗体、ｐｉ３キナーゼ−デルタ阻害剤および抗ｐｄ−１抗体または抗ｐｄ−ｌ１抗体の組み合わせ Download PDF

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JP2019526595A
JP2019526595A JP2019512763A JP2019512763A JP2019526595A JP 2019526595 A JP2019526595 A JP 2019526595A JP 2019512763 A JP2019512763 A JP 2019512763A JP 2019512763 A JP2019512763 A JP 2019512763A JP 2019526595 A JP2019526595 A JP 2019526595A
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kinase
delta inhibitor
ubrituximab
antibody
weeks
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エス． ワイス，マイケル
エス． ワイス，マイケル
ピー． ミスキン，ハリ
ピー． ミスキン，ハリ
スポルテリ，ピーター
Original Assignee
ティージー セラピューティクス，インコーポレイテッド
ティージー セラピューティクス，インコーポレイテッド
ルヒゼン ファーマスティカルズ エスエー
ルヒゼン ファーマスティカルズ エスエー
ラボラトワ フランセーズ デュ フラクションメント エ デ バイオテクノロジーズ
ラボラトワ フランセーズ デュ フラクションメント エ デ バイオテクノロジーズ
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    • A—HUMAN NECESSITIES
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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JP2019512763A 2016-09-09 2017-09-08 血液癌を治療するための抗ｃｄ２０抗体、ｐｉ３キナーゼ−デルタ阻害剤および抗ｐｄ−１抗体または抗ｐｄ−ｌ１抗体の組み合わせ Pending JP2019526595A (ja)

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US201662385723P 2016-09-09 2016-09-09
US62/385,723 2016-09-09
PCT/US2017/050825 WO2018049263A1 (en) 2016-09-09 2017-09-08 Combination of an anti-cd20 antibody, pi3 kinase-delta inhibitor, and anti-pd-1 or anti-pd-l1 antibody for treating hematological cancers

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JP2019526595A true JP2019526595A (ja) 2019-09-19
JP2019526595A5 JP2019526595A5 (https=) 2020-10-15

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US (1) US20190247399A1 (https=)
EP (1) EP3509634A1 (https=)
JP (1) JP2019526595A (https=)
KR (1) KR20190068521A (https=)
CN (1) CN110191720A (https=)
AU (1) AU2017322501A1 (https=)
BR (1) BR112019004185A2 (https=)
CA (1) CA3035976A1 (https=)
CL (1) CL2019000585A1 (https=)
EA (1) EA201990374A1 (https=)
IL (1) IL265194A (https=)
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ES2989438T3 (es) 2018-09-19 2024-11-26 Novo Nordisk Healthcare Ag Activación de la piruvato cinasa R
US12053458B2 (en) 2018-09-19 2024-08-06 Novo Nordisk Health Care Ag Treating sickle cell disease with a pyruvate kinase R activating compound
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JP2022540466A (ja) * 2019-07-15 2022-09-15 ジョンソン、マッセイ、パブリック、リミテッド、カンパニー 非晶質ウムブラリシブモノトシレート
US20220378756A1 (en) 2019-09-19 2022-12-01 Forma Therapeutics, Inc. Activating pyruvate kinase r
WO2022171121A1 (zh) * 2021-02-10 2022-08-18 同润生物医药(上海)有限公司 治疗肿瘤的方法和组合
US12128035B2 (en) 2021-03-19 2024-10-29 Novo Nordisk Health Care Ag Activating pyruvate kinase R
CN118922208A (zh) * 2022-02-28 2024-11-08 贾斯帕医疗公司 用于消耗患病造血干细胞的组合物和方法
CN115141092A (zh) * 2022-07-27 2022-10-04 诚达药业股份有限公司 一种抗淋巴瘤药物相关化合物的合成方法

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WO2018049263A1 (en) 2018-03-15
CL2019000585A1 (es) 2020-05-29
CN110191720A (zh) 2019-08-30
US20190247399A1 (en) 2019-08-15
EP3509634A1 (en) 2019-07-17
EA201990374A1 (ru) 2019-09-30
MX2019002728A (es) 2019-08-16
BR112019004185A2 (pt) 2019-09-03
AU2017322501A1 (en) 2019-03-28
IL265194A (en) 2019-05-30
KR20190068521A (ko) 2019-06-18

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