JP2019526262A5 - - Google Patents
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- JP2019526262A5 JP2019526262A5 JP2019512264A JP2019512264A JP2019526262A5 JP 2019526262 A5 JP2019526262 A5 JP 2019526262A5 JP 2019512264 A JP2019512264 A JP 2019512264A JP 2019512264 A JP2019512264 A JP 2019512264A JP 2019526262 A5 JP2019526262 A5 JP 2019526262A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- recombinant
- lab
- pharmaceutical composition
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022010063A JP2022061035A (ja) | 2016-09-02 | 2022-01-26 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
| JP2024009123A JP2024047590A (ja) | 2016-09-02 | 2024-01-25 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662383079P | 2016-09-02 | 2016-09-02 | |
| US62/383,079 | 2016-09-02 | ||
| PCT/IB2017/055287 WO2018042390A1 (en) | 2016-09-02 | 2017-09-02 | Genetically modified bacteria stably expressing il-10 and insulin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022010063A Division JP2022061035A (ja) | 2016-09-02 | 2022-01-26 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019526262A JP2019526262A (ja) | 2019-09-19 |
| JP2019526262A5 true JP2019526262A5 (https=) | 2020-10-15 |
| JP7016865B2 JP7016865B2 (ja) | 2022-03-03 |
Family
ID=60120085
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019512264A Expired - Fee Related JP7016865B2 (ja) | 2016-09-02 | 2017-09-02 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
| JP2022010063A Pending JP2022061035A (ja) | 2016-09-02 | 2022-01-26 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
| JP2024009123A Pending JP2024047590A (ja) | 2016-09-02 | 2024-01-25 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022010063A Pending JP2022061035A (ja) | 2016-09-02 | 2022-01-26 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
| JP2024009123A Pending JP2024047590A (ja) | 2016-09-02 | 2024-01-25 | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10858663B2 (https=) |
| EP (1) | EP3506932B1 (https=) |
| JP (3) | JP7016865B2 (https=) |
| CN (2) | CN118813511A (https=) |
| AU (1) | AU2017319707B2 (https=) |
| CA (1) | CA3035151A1 (https=) |
| RU (1) | RU2768027C2 (https=) |
| WO (1) | WO2018042390A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118813511A (zh) * | 2016-09-02 | 2024-10-22 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 稳定表达il-10和胰岛素的遗传修饰的细菌 |
| RU2021135949A (ru) | 2016-09-13 | 2022-04-14 | Интрексон Актобиотикс Н.В. | Мукоадгезивный микроорганизм |
| WO2020132595A1 (en) * | 2018-12-21 | 2020-06-25 | The Regents Of The University Of California | Il-10-containing vaccines and uses thereof |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | １型糖尿病を治療するための方法 |
| EP4647489A1 (en) * | 2023-01-03 | 2025-11-12 | Shenzhen Synthetica Pioneering Co., Ltd. | Bacteria secreting interleukin-10 |
| CN116726158A (zh) * | 2023-04-24 | 2023-09-12 | 中国医学科学院医学生物学研究所 | 一种多表位1型糖尿病疫苗及其制备方法 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB227835A (en) | 1924-01-15 | 1925-04-09 | Harry Odell | Improvements in feeding mechanism for embossing and other printing presses |
| US4919918A (en) | 1988-03-14 | 1990-04-24 | Spectrum Consumer Products Co., Inc. | Non-alcoholic mouthwash |
| US5972685A (en) | 1988-07-21 | 1999-10-26 | Iowa State University Research Foundation, Inc. | Oral administration of coprostanol producing microorganisms to humans to decrease plasma cholesterol concentration |
| GB9126306D0 (en) | 1991-12-11 | 1992-02-12 | Unilever Plc | Mouthwash compositions |
| WO1993017117A1 (en) | 1992-02-27 | 1993-09-02 | Lynxvale Limited | Heterologous gene expression in lactococcus, and the expression products therefrom |
| US5223285A (en) | 1992-03-31 | 1993-06-29 | Abbott Laboratories | Nutritional product for pulmonary patients |
| US5700782A (en) | 1993-05-28 | 1997-12-23 | Abbott Laboratories | Enteral nutritional product |
| WO1996032486A1 (en) | 1995-04-11 | 1996-10-17 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Method for the construction of vectors for lactic acid bacteria like lactobacillus such that the bacteria can efficiently express, secrete and display proteins at the surface |
| US5695746A (en) | 1995-07-28 | 1997-12-09 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Liquid dentifrice with mouthwash fresh taste |
| WO1997026855A1 (en) | 1996-01-24 | 1997-07-31 | Warner-Lambert Company | Peroxide/essential oils containing mouthwash compositions and two-part mouthwash systems |
| GB9611364D0 (en) | 1996-05-31 | 1996-08-07 | Smithkline Beecham Plc | Composition |
| US5993785A (en) | 1996-09-18 | 1999-11-30 | Erling Johansen | Mouthwash compositions |
| US5869118A (en) | 1996-11-13 | 1999-02-09 | Abbott Laboratories | Gellan gum to improve physical stability of liquid nutritional products |
| US6171611B1 (en) | 1997-11-12 | 2001-01-09 | Dante J. Picciano | Iodine-containing nasal moisturizing saline and mouthwash solutions |
| US5897872A (en) | 1997-11-12 | 1999-04-27 | Picciano; Dante J. | Iodine-containing nasal moisturizing saline solution |
| MXPA01003197A (es) | 1998-09-28 | 2004-04-21 | Warner Lambert Co | Suministro enterico y colonico utilizando capsulas de chpm. |
| WO2000022909A2 (en) | 1998-10-19 | 2000-04-27 | Biotech Australia Pty. Limited | Systems for oral delivery |
| DK1383897T3 (da) | 2001-05-03 | 2006-10-30 | Vlaams Interuniv Inst Biotech | Selv-containing Lactococcus-stamme |
| US20040043003A1 (en) * | 2002-01-31 | 2004-03-04 | Wei Chen | Clinical grade vectors based on natural microflora for use in delivering therapeutic compositions |
| EP1536749A2 (en) | 2002-07-08 | 2005-06-08 | Joe S. Wilkins, Jr. | Antibacterial formulations |
| AU2003303222A1 (en) * | 2002-12-19 | 2004-07-14 | Universiteit Gent | Mutant proteins showing increased secretion |
| ES2405552T3 (es) * | 2005-11-29 | 2013-05-31 | Actogenix N.V. | Inducción de tolerancia mucosa a antiantígenos de células beta de islotes pancreáticos |
| AU2008204442B2 (en) * | 2007-01-12 | 2013-03-14 | Intrexon Actobiotics Nv | Lactococcus promoters and uses thereof |
| WO2008090223A2 (en) | 2007-01-25 | 2008-07-31 | Actogenix N.V. | Treatment of immune disease by mucosal delivery of antigens using genetically modified lactobacillus |
| BRPI0809448A2 (pt) * | 2007-03-28 | 2014-09-09 | Alimentary Health Ltd | Cepas de bifidobacterium probióticas |
| JP5572972B2 (ja) * | 2009-03-16 | 2014-08-20 | Ｊｎｃ株式会社 | インスリン分泌促進剤などの薬物のスクリーニング方法 |
| CA2760248C (en) | 2009-04-30 | 2019-05-28 | Actogenix Nv | Cryoprotectants for freeze drying of lactic acid bacteria |
| WO2012164083A1 (en) * | 2011-06-01 | 2012-12-06 | Actogenix N.V. | Polycistronic expression system for bacteria |
| JP6117212B2 (ja) * | 2011-09-23 | 2017-04-19 | イントレクソン・アクトバイオテイクス・エヌブイＩｎｔｒｅｘｏｎ Ａｃｔｏｂｉｏｔｉｃｓ ＮＶ | 改変されたグラム陽性菌及びその使用 |
| HUE038336T2 (hu) * | 2011-09-23 | 2018-10-29 | Intrexon Actobiotics Nv | Módosított gram-pozitív baktériumok és alkalmazásaik |
| CN118813511A (zh) * | 2016-09-02 | 2024-10-22 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 稳定表达il-10和胰岛素的遗传修饰的细菌 |
-
2017
- 2017-09-02 CN CN202410943767.1A patent/CN118813511A/zh not_active Withdrawn
- 2017-09-02 US US16/329,321 patent/US10858663B2/en active Active
- 2017-09-02 AU AU2017319707A patent/AU2017319707B2/en active Active
- 2017-09-02 CN CN201780054190.7A patent/CN109843320A/zh active Pending
- 2017-09-02 RU RU2019104948A patent/RU2768027C2/ru active
- 2017-09-02 CA CA3035151A patent/CA3035151A1/en active Pending
- 2017-09-02 EP EP17784999.9A patent/EP3506932B1/en active Active
- 2017-09-02 WO PCT/IB2017/055287 patent/WO2018042390A1/en not_active Ceased
- 2017-09-02 JP JP2019512264A patent/JP7016865B2/ja not_active Expired - Fee Related
-
2020
- 2020-11-09 US US17/092,624 patent/US11549118B2/en active Active
-
2022
- 2022-01-26 JP JP2022010063A patent/JP2022061035A/ja active Pending
- 2022-11-29 US US18/059,689 patent/US12359210B2/en active Active
-
2024
- 2024-01-25 JP JP2024009123A patent/JP2024047590A/ja active Pending
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