AU2003303222A1 - Mutant proteins showing increased secretion - Google Patents

Mutant proteins showing increased secretion

Info

Publication number
AU2003303222A1
AU2003303222A1 AU2003303222A AU2003303222A AU2003303222A1 AU 2003303222 A1 AU2003303222 A1 AU 2003303222A1 AU 2003303222 A AU2003303222 A AU 2003303222A AU 2003303222 A AU2003303222 A AU 2003303222A AU 2003303222 A1 AU2003303222 A1 AU 2003303222A1
Authority
AU
Australia
Prior art keywords
mutant proteins
increased secretion
showing increased
proteins showing
secretion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003303222A
Other versions
AU2003303222A8 (en
Inventor
Sabine Neirynck
Lothar Steidler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Gent
Vlaams Instituut voor Biotechnologie VIB
Original Assignee
Vlaams Instituut voor Biotechnologie VIB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vlaams Instituut voor Biotechnologie VIB filed Critical Vlaams Instituut voor Biotechnologie VIB
Publication of AU2003303222A8 publication Critical patent/AU2003303222A8/en
Publication of AU2003303222A1 publication Critical patent/AU2003303222A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5428—IL-10
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2003303222A 2002-12-19 2003-12-18 Mutant proteins showing increased secretion Abandoned AU2003303222A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02080625 2002-12-19
EP02080625.3 2002-12-19
PCT/EP2003/051050 WO2004056850A2 (en) 2002-12-19 2003-12-18 Mutant proteins showing increased secretion

Publications (2)

Publication Number Publication Date
AU2003303222A8 AU2003303222A8 (en) 2004-07-14
AU2003303222A1 true AU2003303222A1 (en) 2004-07-14

Family

ID=32668874

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003303222A Abandoned AU2003303222A1 (en) 2002-12-19 2003-12-18 Mutant proteins showing increased secretion

Country Status (2)

Country Link
AU (1) AU2003303222A1 (en)
WO (1) WO2004056850A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016519108A (en) 2013-04-18 2016-06-30 アルモ・バイオサイエンシーズ・インコーポレイテッド Method for using interleukin-10 for the treatment of diseases and disorders
US20160068583A1 (en) * 2013-04-24 2016-03-10 Armo Biosciences, Inc. Interleukin-10 Compositions and Uses Thereof
WO2014204816A2 (en) 2013-06-17 2014-12-24 Armo Biosciences, Inc. Method for assessing protein identity and stability
US10010588B2 (en) 2013-08-30 2018-07-03 Armo Biosciences, Inc. Methods of using pegylated interleukin-10 for treating hyperlipidemia
KR20160079114A (en) 2013-11-11 2016-07-05 아르모 바이오사이언시스 인코포레이티드 Methods of using interleukin-10 for treating diseases and disorders
WO2015187295A2 (en) 2014-06-02 2015-12-10 Armo Biosciences, Inc. Methods of lowering serum cholesterol
JP2017536098A (en) 2014-10-14 2017-12-07 アルモ・バイオサイエンシーズ・インコーポレイテッド Interleukin-15 composition and use thereof
WO2016064817A1 (en) 2014-10-22 2016-04-28 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
US10618970B2 (en) 2015-02-03 2020-04-14 Armo Biosciences, Inc. Method of treating cancer with IL-10 and antibodies that induce ADCC
AU2016268403A1 (en) 2015-05-28 2017-12-07 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
JP7053453B2 (en) 2015-08-25 2022-04-12 アルモ・バイオサイエンシーズ・インコーポレイテッド How to use interleukin 10 to treat diseases and disorders
JP7016865B2 (en) * 2016-09-02 2022-03-03 イントレクソン・アクトバイオテイクス・エヌブイ Gene-modified bacteria that stably express IL-10 and insulin
CN113811549A (en) 2019-02-21 2021-12-17 Xencor股份有限公司 Non-targeted and targeted IL-10 FC fusion proteins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1383897T3 (en) * 2001-05-03 2006-10-30 Vlaams Interuniv Inst Biotech Self-containing Lactococcus strain

Also Published As

Publication number Publication date
AU2003303222A8 (en) 2004-07-14
WO2004056850A2 (en) 2004-07-08
WO2004056850A3 (en) 2004-09-30

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Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL 18, NO 32, PAGE(S) 8486 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME VIB VZW, APPLICATION NO. 2003303222, UNDER INID (71) CORRECT THE NAME TO READ UNIVERSITEIT GENT; VIB VZW

MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase