AU2003303222A8 - Mutant proteins with increased secretion - Google Patents

Mutant proteins with increased secretion

Info

Publication number
AU2003303222A8
AU2003303222A8 AU2003303222A AU2003303222A AU2003303222A8 AU 2003303222 A8 AU2003303222 A8 AU 2003303222A8 AU 2003303222 A AU2003303222 A AU 2003303222A AU 2003303222 A AU2003303222 A AU 2003303222A AU 2003303222 A8 AU2003303222 A8 AU 2003303222A8
Authority
AU
Australia
Prior art keywords
mutant proteins
increased secretion
secretion
increased
mutant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003303222A
Other versions
AU2003303222A1 (en
Inventor
Lothar Steidler
Sabine Neirynck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Gent
Vlaams Instituut voor Biotechnologie VIB
Original Assignee
Universiteit Gent
Vlaams Instituut voor Biotechnologie VIB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universiteit Gent, Vlaams Instituut voor Biotechnologie VIB filed Critical Universiteit Gent
Publication of AU2003303222A1 publication Critical patent/AU2003303222A1/en
Publication of AU2003303222A8 publication Critical patent/AU2003303222A8/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5428—IL-10
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
AU2003303222A 2002-12-19 2003-12-18 Mutant proteins showing increased secretion Abandoned AU2003303222A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02080625.3 2002-12-19
EP02080625 2002-12-19
PCT/EP2003/051050 WO2004056850A2 (en) 2002-12-19 2003-12-18 Mutant proteins showing increased secretion

Publications (2)

Publication Number Publication Date
AU2003303222A1 AU2003303222A1 (en) 2004-07-14
AU2003303222A8 true AU2003303222A8 (en) 2004-07-14

Family

ID=32668874

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003303222A Abandoned AU2003303222A1 (en) 2002-12-19 2003-12-18 Mutant proteins showing increased secretion

Country Status (2)

Country Link
AU (1) AU2003303222A1 (en)
WO (1) WO2004056850A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2679889C2 (en) 2013-04-18 2019-02-14 Армо Байосайенсиз, Инк. Methods of using interleukin-10 for treating diseases and disorders
JP2016526014A (en) * 2013-04-24 2016-09-01 アルモ・バイオサイエンシーズ・インコーポレイテッド Interleukin-10 composition and use thereof
CA2914837A1 (en) 2013-06-17 2014-12-24 Armo Biosciences, Inc. Method for assessing protein identity and stability
US10010588B2 (en) 2013-08-30 2018-07-03 Armo Biosciences, Inc. Methods of using pegylated interleukin-10 for treating hyperlipidemia
WO2015070060A1 (en) 2013-11-11 2015-05-14 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
CN106573072A (en) 2014-06-02 2017-04-19 阿尔莫生物科技股份有限公司 Methods of lowering serum cholesterol
EP3206713A4 (en) 2014-10-14 2018-06-27 Armo Biosciences, Inc. Interleukin-15 compositions and uses thereof
CN107106655A (en) 2014-10-22 2017-08-29 阿尔莫生物科技股份有限公司 The method that disease and illness are treated using interleukin 10
WO2016126615A1 (en) 2015-02-03 2016-08-11 Armo Biosciences, Inc. Methods of using interleukin-10 for treating diseases and disorders
EP3302547A1 (en) 2015-05-28 2018-04-11 Armo Biosciences, Inc. Pegylated interleukin-10 for use in treating cancer
AU2016312510A1 (en) 2015-08-25 2018-03-08 Armo Biosciences, Inc. Methods of using Interleukin-10 for treating diseases and disorders
CN109843320A (en) * 2016-09-02 2019-06-04 英特瑞克斯顿阿克图比奥帝克斯有限公司 Stablize the bacterium of the genetic modification of expression IL-10 and insulin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002090551A2 (en) * 2001-05-03 2002-11-14 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Self-containing lactococcus strain

Also Published As

Publication number Publication date
AU2003303222A1 (en) 2004-07-14
WO2004056850A2 (en) 2004-07-08
WO2004056850A3 (en) 2004-09-30

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Legal Events

Date Code Title Description
TH Corrigenda

Free format text: IN VOL 18, NO 32, PAGE(S) 8486 UNDER THE HEADING APPLICATIONS OPI - NAME INDEX UNDER THE NAME VIB VZW, APPLICATION NO. 2003303222, UNDER INID (71) CORRECT THE NAME TO READ UNIVERSITEIT GENT; VIB VZW

MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase